Genome-Wide Association Study of Type 2 Diabetes in Finns Detects Multiple Susceptibility Variants
Scott, Laura J, Mohlke, Karen L, Bonnycastle, Lori L, Willer, Cristen J, Li, Yun, Duren, William L, Erdos, Michael R, Stringham, Heather M, Chines, Peter S, Jackson, Anne U, Prokunina-Olsson, Ludmila, Ding, Chia-Jen, Swift, Amy J, Narisu, Narisu, Hu, Tianle, Pruim, Randall, Xiao, Rui, Li, Xiao-Yi, Conneely, Karen N, Riebow, Nancy L, Sprau, Andrew G, Tong, Maurine, White, Peggy P, Hetrick, Kurt N, Barnhart, Michael W, Bark, Craig W, Goldstein, Janet L, Watkins, Lee, Xiang, Fang, Saramies, Jouko, Buchanan, Thomas A, Watanabe, Richard M, Valle, Timo T, Kinnunen, Leena, Abecasis, Gonçalo R, Pugh, Elizabeth W, Doheny, Kimberly F, Bergman, Richard N, Tuomilehto, Jaakko, Collins, Francis S, Boehnke, Michael
Published in Science (American Association for the Advancement of Science) (01.06.2007)
Published in Science (American Association for the Advancement of Science) (01.06.2007)
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Systematic comparison of three genomic enrichment methods for massively parallel DNA sequencing
Teer, Jamie K, Bonnycastle, Lori L, Chines, Peter S, Hansen, Nancy F, Aoyama, Natsuyo, Swift, Amy J, Abaan, Hatice Ozel, Albert, Thomas J, Margulies, Elliott H, Green, Eric D, Collins, Francis S, Mullikin, James C, Biesecker, Leslie G
Published in Genome research (01.10.2010)
Published in Genome research (01.10.2010)
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Autosomal Dominant Diabetes Arising From a Wolfram Syndrome 1 Mutation
BONNYCASTLE, Lori L, CHINES, Peter S, NARISU, Narisu, GOLDFEDER, Rachel L, STITZEL, Michael L, SIMIN LU, BOEHNKE, Michael, URANO, Fumihiko, COLLINS, Francis S, LAAKSO, Markku, HARA, Takashi, HUYGHE, Jeroen R, SWIFT, Amy J, HEIKINHEIMO, Pirkko, MAHADEVAN, Jana, PELTONEN, Sirkku, HUOPIO, Hanna, NUUTILA, Pirjo
Published in Diabetes (New York, N.Y.) (01.11.2013)
Published in Diabetes (New York, N.Y.) (01.11.2013)
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Use of microarray hybrid capture and next-generation sequencing to identify the anatomy of a transgene
Dubose, Amanda J, Lichtenstein, Stephen T, Narisu, Narisu, Bonnycastle, Lori L, Swift, Amy J, Chines, Peter S, Collins, Francis S
Published in Nucleic acids research (01.04.2013)
Published in Nucleic acids research (01.04.2013)
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Screening of 134 Single Nucleotide Polymorphisms (SNPs) Previously Associated With Type 2 Diabetes Replicates Association With 12 SNPs in Nine Genes
WILIER, Cristen J, BONNYCASTLE, Lori L, PETRIE, John, ERDOS, Michael R, SWIFT, Amy J, ENLOE, Sareena T, SPRAU, Andrew G, SMITH, Eboni, TONG, Maurine, DOHENY, Kimberly F, PUGH, Elizabeth W, WATANABE, Richard M, CONNEELY, Karen N, BUCHANAN, Thomas A, VALLE, Timo T, BERGMAN, Richard N, TUOMILEHTO, Jaakko, MOHLKE, Karen L, COLLINS, Francis S, BOEHNKE, Michael, DUREN, William L, JACKSON, Anne U, SCOTT, Laura J, NARISU, Narisu, CHINES, Peter S, SKOL, Andrew, STRINGHAM, Heather M
Published in Diabetes (New York, N.Y.) (01.01.2007)
Published in Diabetes (New York, N.Y.) (01.01.2007)
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Additive Effects of Genetic Variation in GCK and G6PC2 on Insulin Secretion and Fasting Glucose
XIA LI, SHU, Yu-Hsiang, LAWRENCE, Jean M, LAAKSO, Markku, ALLAYEE, Hooman, BUCHANAN, Thomas A, WATANABE, Richard M, XIANG, Anny H, TRIGO, Enrique, KUUSISTO, Johanna, HARTIALA, Jaana, SWIFT, Amy J, KAWAKUBO, Miwa, STRINGHAM, Heather M, BONNYCASTLE, Lori L
Published in Diabetes (New York, N.Y.) (01.12.2009)
Published in Diabetes (New York, N.Y.) (01.12.2009)
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Journal Article
Common Variants in Maturity-Onset Diabetes of the Young Genes Contribute to Risk of Type 2 Diabetes in Finns
BONNYCASTLE, Lori L, WILIER, Cristen J, SWIFT, Amy J, DUREN, William L, STRINGHAM, Heather M, ERDOS, Michael R, RIEBOW, Nancy L, BUCHANAN, Thomas A, VALLE, Timo T, TUOMILEHTO, Jaakko, BERGMAN, Richard N, MOHLKE, Karen L, CONNEELY, Karen N, BOEHNKE, Michael, COLLINS, Francis S, JACKSON, Anne U, BURRILL, Cecily P, WATANABE, Richard M, CHINES, Peter S, NARISU, Narisu, SCOTT, Laura J, ENLOE, Sareena T
Published in Diabetes (New York, N.Y.) (01.09.2006)
Published in Diabetes (New York, N.Y.) (01.09.2006)
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Human pancreatic islet microRNAs implicated in diabetes and related traits by large-scale genetic analysis
Taylor, Henry J, Hung, Yu-Han, Narisu, Narisu, Erdos, Michael R, Kanke, Matthew, Yan, Tingfen, Grenko, Caleb M, Swift, Amy J, Bonnycastle, Lori L, Sethupathy, Praveen, Collins, Francis S, Taylor, D Leland
Published in Proceedings of the National Academy of Sciences - PNAS (14.02.2023)
Published in Proceedings of the National Academy of Sciences - PNAS (14.02.2023)
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Functional interrogation of twenty type 2 diabetes-associated genes using isogenic human embryonic stem cell-derived β-like cells
Xue, Dongxiang, Narisu, Narisu, Taylor, D Leland, Zhang, Meili, Grenko, Caleb, Taylor, Henry J, Yan, Tingfen, Tang, Xuming, Sinha, Neelam, Zhu, Jiajun, Vandana, J Jeya, Nok Chong, Angie Chi, Lee, Angela, Mansell, Erin C, Swift, Amy J, Erdos, Michael R, Zhong, Aaron, Bonnycastle, Lori L, Zhou, Ting, Chen, Shuibing, Collins, Francis S
Published in Cell metabolism (07.11.2023)
Published in Cell metabolism (07.11.2023)
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Modeling islet enhancers using deep learning identifies candidate causal variants at loci associated with T2D and glycemic traits
Hudaiberdiev, Sanjarbek, Taylor, D Leland, Song, Wei, Narisu, Narisu, Bhuiyan, Redwan M, Taylor, Henry J, Tang, Xuming, Yan, Tingfen, Swift, Amy J, Bonnycastle, Lori L, Consortium, Diamante, Chen, Shuibing, Stitzel, Michael L, Erdos, Michael R, Ovcharenko, Ivan, Collins, Francis S
Published in Proceedings of the National Academy of Sciences - PNAS (29.08.2023)
Published in Proceedings of the National Academy of Sciences - PNAS (29.08.2023)
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Hydroa vacciniforme–like lymphoproliferative disorder: an EBV disease with a low risk of systemic illness in whites
Cohen, Jeffrey I., Manoli, Irini, Dowdell, Kennichi, Krogmann, Tammy A., Tamura, Deborah, Radecki, Pierce, Bu, Wei, Turk, Siu-Ping, Liepshutz, Kelly, Hornung, Ronald L., Fassihi, Hiva, Sarkany, Robert P., Bonnycastle, Lori L., Chines, Peter S., Swift, Amy J., Myers, Timothy G., Levoska, Melissa A., DiGiovanna, John J., Collins, Francis S., Kraemer, Kenneth H., Pittaluga, Stefania, Jaffe, Elaine S.
Published in Blood (27.06.2019)
Published in Blood (27.06.2019)
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Common variants at 30 loci contribute to polygenic dyslipidemia
Kooner, Jaspal S, Mohlke, Karen L, Groop, Leif, Schadt, Eric E, O'Donnell, Christopher J, Zelenika, Diana, Sanna, Serena, Bonnycastle, Lori L, Yang, Qiong, Hercberg, Serge, Schlessinger, David, Chambers, John C, Laakso, Markku, Li, Yun, Ordovas, Jose M, Ferrucci, Luigi, Orho-Melander, Marju, Surti, Aarti, de Bakker, Paul I W, Clarke, Robert, Kathiresan, Sekar, Tanaka, Toshiko, Stringham, Heather M, Salomaa, Veikko, Willer, Cristen J, Scott, Laura J, Tuomilehto, Jaakko, Swift, Amy J, Lathrop, G Mark, Melander, Olle, Collins, Rory, Dupuis, Josée, Collins, Francis S, Lunetta, Kathryn L, Jackson, Anne U, Galan, Pilar, Peltonen, Leena, Peloso, Gina M, Musunuru, Kiran, Kuusisto, Johanna, Sundvall, Jouko, Crawford, Gabriel, Guiducci, Candace, Meneton, Pierre, Lakatta, Edward G, Altshuler, David, Scheet, Paul, Burtt, Noel P, Kaplan, Lee, Abecasis, Gonçalo R, Parish, Sarah, Uda, Manuela, Kubalanza, Kari A, Scuteri, Angelo, Boehnke, Michael, Voight, Benjamin F, Cupples, L Adrienne, Demissie, Serkalem, Bennett, Derrick, Bergman, Richard N, Morken, Mario A
Published in Nature genetics (01.01.2009)
Published in Nature genetics (01.01.2009)
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Single-cell transcriptomic profiling of human pancreatic islets reveals genes responsive to glucose exposure over 24 h
Grenko, Caleb M., Taylor, Henry J., Bonnycastle, Lori L., Xue, Dongxiang, Lee, Brian N., Weiss, Zoe, Yan, Tingfen, Swift, Amy J., Mansell, Erin C., Lee, Angela, Robertson, Catherine C., Narisu, Narisu, Erdos, Michael R., Chen, Shuibing, Collins, Francis S., Taylor, D. Leland
Published in Diabetologia (05.07.2024)
Published in Diabetologia (05.07.2024)
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Newly identified loci that influence lipid concentrations and risk of coronary artery disease
Narisu, Narisu, Lakatta, Edward, Mohlke, Karen L, Willer, Cristen J, Shuldiner, Alan R, Najjar, Samer S, Davey-Smith, George, Scuteri, Angelo, Zelenika, Diana, Li, Yun, Galan, Pilar, Shen, Haiqing, Schlessinger, David, Lawlor, Debbie A, Collins, Francis S, Strait, James, Meneton, Pierre, Duren, William L, Clarke, Robert, Watanabe, Richard M, Ebrahim, Shah, Mulas, Antonella, Uda, Manuela, Swift, Amy J, Albai, Giuseppe, Bergman, Richard N, Maschio, Andrea, Collins, Rory, Tuomilehto, Jaakko, Scott, Laura J, Bonnycastle, Lori L, Hercberg, Serge, Busonero, Fabio, Boehnke, Michael, Nagaraja, Ramaiah, Jackson, Anne U, Ben-Shlomo, Yoav, Morken, Mario A, Heath, Simon C, Stringham, Heather M, Abecasis, Gonçalo R, Cao, Antonio, Scheet, Paul A, Lathrop, G Mark, Parish, Sarah, Bennett, Derrick, Chen, Wei-Min, Sundvall, Jouko, Timpson, Nicholas J, Sanna, Serena
Published in Nature genetics (01.02.2008)
Published in Nature genetics (01.02.2008)
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Generation of Human Isogenic Induced Pluripotent Stem Cell Lines with CRISPR Prime Editing
Bonnycastle, Lori L, Swift, Amy J, Mansell, Erin C, Lee, Angela, Winnicki, Elizabeth, Li, Elizabeth S, Robertson, Catherine C, Parsons, Victoria A, Huynh, Trung, Krilow, Chad, Mohlke, Karen L, Erdos, Michael R, Narisu, Narisu, Collins, Francis S
Published in CRISPR journal (01.02.2024)
Published in CRISPR journal (01.02.2024)
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Journal Article
Variations in the G6PC2/ABCB11 genomic region are associated with fasting glucose levels
Chen, Wei-Min, Erdos, Michael R, Jackson, Anne U, Saxena, Richa, Sanna, Serena, Silver, Kristi D, Timpson, Nicholas J, Hansen, Torben, Orrù, Marco, Grazia Piras, Maria, Bonnycastle, Lori L, Willer, Cristen J, Lyssenko, Valeriya, Shen, Haiqing, Kuusisto, Johanna, Ebrahim, Shah, Sestu, Natascia, Duren, William L, Spada, Maria Cristina, Stringham, Heather M, Scott, Laura J, Olla, Nazario, Swift, Amy J, Najjar, Samer, Mitchell, Braxton D, Lawlor, Debbie A, Smith, George Davey, Ben-Shlomo, Yoav, Andersen, Gitte, Borch-Johnsen, Knut, Jørgensen, Torben, Saramies, Jouko, Valle, Timo T, Buchanan, Thomas A, Shuldiner, Alan R, Lakatta, Edward, Bergman, Richard N, Uda, Manuela, Tuomilehto, Jaakko, Pedersen, Oluf, Cao, Antonio, Groop, Leif, Mohlke, Karen L, Laakso, Markku, Schlessinger, David, Collins, Francis S, Altshuler, David, Abecasis, Gonçalo R, Boehnke, Michael, Scuteri, Angelo, Watanabe, Richard M
Published in The Journal of clinical investigation (01.07.2008)
Published in The Journal of clinical investigation (01.07.2008)
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Single-cell transcriptomics from human pancreatic islets: sample preparation matters
Bonnycastle, Lori L, Gildea, Derek E, Yan, Tingfen, Narisu, Narisu, Swift, Amy J, Wolfsberg, Tyra G, Erdos, Michael R, Collins, Francis S
Published in Biology methods and protocols (2020)
Published in Biology methods and protocols (2020)
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Correlation of rare coding variants in the gene encoding human glucokinase regulatory protein with phenotypic, cellular, and kinetic outcomes
Rees, Matthew G, Ng, David, Ruppert, Sarah, Turner, Clesson, Beer, Nicola L, Swift, Amy J, Morken, Mario A, Below, Jennifer E, Blech, Ilana, Mullikin, James C, McCarthy, Mark I, Biesecker, Leslie G, Gloyn, Anna L, Collins, Francis S
Published in The Journal of clinical investigation (01.01.2012)
Published in The Journal of clinical investigation (01.01.2012)
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Journal Article
Human longevity and common variations in the LMNA gene: a meta‐analysis
Conneely, Karen N., Capell, Brian C., Erdos, Michael R., Sebastiani, Paola, Solovieff, Nadia, Swift, Amy J., Baldwin, Clinton T., Budagov, Temuri, Barzilai, Nir, Atzmon, Gil, Puca, Annibale A., Perls, Thomas T., Geesaman, Bard J., Boehnke, Michael, Collins, Francis S.
Published in Aging cell (01.06.2012)
Published in Aging cell (01.06.2012)
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Journal Article
Single-cell transcriptomic profiling of human pancreatic islets reveals genes responsive to glucose exposure over 24 hours
Grenko, Caleb M, Bonnycastle, Lori L, Taylor, Henry J, Yan, Tingfen, Swift, Amy J, Robertson, Catherine C, Narisu, Narisu, Erdos, Michael R, Collins, Francis S, Taylor, D Leland
Published in bioRxiv (17.07.2023)
Published in bioRxiv (17.07.2023)
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