Selecting instruments for Mendelian randomization in the wake of genome-wide association studies
Swerdlow, Daniel I, Kuchenbaecker, Karoline B, Shah, Sonia, Sofat, Reecha, Holmes, Michael V, White, Jon, Mindell, Jennifer S, Kivimaki, Mika, Brunner, Eric J, Whittaker, John C, Casas, Juan P, Hingorani, Aroon D
Published in International journal of epidemiology (01.10.2016)
Published in International journal of epidemiology (01.10.2016)
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Journal Article
Single Ascending Dose Study of a Short Interfering RNA Targeting Lipoprotein(a) Production in Individuals With Elevated Plasma Lipoprotein(a) Levels
Nissen, Steven E, Wolski, Kathy, Balog, Craig, Swerdlow, Daniel I, Scrimgeour, Alison C, Rambaran, Curtis, Wilson, Rosamund J, Boyce, Malcom, Ray, Kausik K, Cho, Leslie, Watts, Gerald F, Koren, Michael, Turner, Traci, Stroes, Erik S, Melgaard, Carrie, Campion, Giles V
Published in JAMA : the journal of the American Medical Association (03.05.2022)
Published in JAMA : the journal of the American Medical Association (03.05.2022)
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Journal Article
Treatment and prevention of lipoprotein(a)-mediated cardiovascular disease: the emerging potential of RNA interference therapeutics
Swerdlow, Daniel I, Rider, David A, Yavari, Arash, Wikström Lindholm, Marie, Campion, Giles V, Nissen, Steven E
Published in Cardiovascular research (25.03.2022)
Published in Cardiovascular research (25.03.2022)
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Journal Article
Pre-clinical assessment of SLN360, a novel siRNA targeting LPA, developed to address elevated lipoprotein (a) in cardiovascular disease
Rider, David A., Eisermann, Mona, Löffler, Kathrin, Aleku, Manuela, Swerdlow, Daniel I., Dames, Sibylle, Hauptmann, Judith, Morrison, Eliot, Lindholm, Marie Wikström, Schubert, Steffen, Campion, Giles
Published in Atherosclerosis (01.05.2022)
Published in Atherosclerosis (01.05.2022)
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Journal Article
Association of Lipid Fractions With Risks for Coronary Artery Disease and Diabetes
White, Jon, Swerdlow, Daniel I, Preiss, David, Fairhurst-Hunter, Zammy, Keating, Brendan J, Asselbergs, Folkert W, Sattar, Naveed, Humphries, Steve E, Hingorani, Aroon D, Holmes, Michael V
Published in JAMA cardiology (01.09.2016)
Published in JAMA cardiology (01.09.2016)
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Journal Article
Causal Effects of Body Mass Index on Cardiometabolic Traits and Events: A Mendelian Randomization Analysis
Holmes, Michael V., Lange, Leslie A., Palmer, Tom, Lanktree, Matthew B., North, Kari E., Almoguera, Berta, Buxbaum, Sarah, Chandrupatla, Hareesh R., Elbers, Clara C., Guo, Yiran, Hoogeveen, Ron C., Li, Jin, Li, Yun R., Swerdlow, Daniel I., Cushman, Mary, Price, Tom S., Curtis, Sean P., Fornage, Myriam, Hakonarson, Hakon, Patel, Sanjay R., Redline, Susan, Siscovick, David S., Tsai, Michael Y., Wilson, James G., van der Schouw, Yvonne T., FitzGerald, Garret A., Hingorani, Aroon D., Casas, Juan P., de Bakker, Paul I.W., Rich, Stephen S., Schadt, Eric E., Asselbergs, Folkert W., Reiner, Alex P., Keating, Brendan J.
Published in American journal of human genetics (06.02.2014)
Published in American journal of human genetics (06.02.2014)
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Journal Article
Mendelian randomization for studying the effects of perturbing drug targets
Gill, Dipender, Georgakis, Marios K., Walker, Venexia M., Schmidt, A. Floriaan, Gkatzionis, Apostolos, Freitag, Daniel F., Finan, Chris, Hingorani, Aroon D., Howson, Joanna M.M., Burgess, Stephen, Swerdlow, Daniel I., Davey Smith, George, Holmes, Michael V., Dichgans, Martin, Scott, Robert A, Zheng, Jie, Psaty, Bruce M., Davies, Neil M.
Published in Wellcome open research (2021)
Published in Wellcome open research (2021)
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Journal Article
Mendelian randomisation study for statin treatment – Authors' reply
Swerdlow, Daniel I, Preiss, David, Hingorani, Aroon D, Sattar, Naveed
Published in The Lancet (British edition) (16.05.2015)
Published in The Lancet (British edition) (16.05.2015)
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Journal Article
Mendelian randomization for studying the effects of perturbing drug targets
Gill, Dipender, Georgakis, Marios K, Walker, Venexia M, Schmidt, A Floriaan, Gkatzionis, Apostolos, Freitag, Daniel F, Finan, Chris, Hingorani, Aroon D, Howson, Joanna M M, Burgess, Stephen, Swerdlow, Daniel I, Davey Smith, George, Holmes, Michael V, Dichgans, Martin, Scott, Robert A, Zheng, Jie, Psaty, Bruce M, Davies, Neil M
Published in Wellcome open research (2021)
Published in Wellcome open research (2021)
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Journal Article
Genetic Association of Lipids and Lipid Drug Targets With Abdominal Aortic Aneurysm: A Meta-analysis
Harrison, Seamus C, Holmes, Michael V, Burgess, Stephen, Asselbergs, Folkert W, Jones, Gregory T, Baas, Annette F, van 't Hof, F N, de Bakker, Paul I W, Blankensteijn, Jan D, Powell, Janet T, Saratzis, Athanasios, de Borst, Gert J, Swerdlow, Daniel I, van der Graaf, Yolanda, van Rij, Andre M, Carey, David J, Elmore, James R, Tromp, Gerard, Kuivaniemi, Helena, Sayers, Robert D, Samani, Nilesh J, Bown, Matthew J, Humphries, Steve E
Published in JAMA cardiology (01.01.2018)
Published in JAMA cardiology (01.01.2018)
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Harnessing publicly available genetic data to prioritize lipid modifying therapeutic targets for prevention of coronary heart disease based on dysglycemic risk
Tragante, Vinicius, Asselbergs, Folkert W., Swerdlow, Daniel I., Palmer, Tom M., Moore, Jason H., de Bakker, Paul I. W., Keating, Brendan J., Holmes, Michael V.
Published in Human genetics (01.05.2016)
Published in Human genetics (01.05.2016)
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Journal Article
Influence of common genetic variation on blood lipid levels, cardiovascular risk, and coronary events in two British prospective cohort studies
Shah, Sonia, Casas, Juan P, Gaunt, Tom R, Cooper, Jackie, Drenos, Fotios, Zabaneh, Delilah, Swerdlow, Daniel I, Shah, Tina, Sofat, Reecha, Palmen, Jutta, Kumari, Meena, Kivimaki, Mika, Ebrahim, Shah, Smith, George Davey, Lawlor, Debbie A, Talmud, Philippa J, Whittaker, John, Day, Ian N M, Hingorani, Aroon D, Humphries, Steve E
Published in European heart journal (01.04.2013)
Published in European heart journal (01.04.2013)
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Journal Article
Genetic Risk Factors and Mendelian Randomization in Cardiovascular Disease
Swerdlow, Daniel I., Hingorani, Aroon D., Humphries, Steve E.
Published in Current cardiology reports (01.05.2015)
Published in Current cardiology reports (01.05.2015)
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Journal Article
The genetics of coronary heart disease
SWERDLOW, Daniel I, HOLMES, Michael V, HARRISON, Seamus, HUMPHRIES, Steve E
Published in British medical bulletin (01.06.2012)
Published in British medical bulletin (01.06.2012)
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