Integrated Metabolic and Epigenomic Reprograming by H3K27M Mutations in Diffuse Intrinsic Pontine Gliomas
Chung, Chan, Sweha, Stefan R., Pratt, Drew, Tamrazi, Benita, Panwalkar, Pooja, Banda, Adam, Bayliss, Jill, Hawes, Debra, Yang, Fusheng, Lee, Ho-Joon, Shan, Mengrou, Cieslik, Marcin, Qin, Tingting, Werner, Christian K., Wahl, Daniel R., Lyssiotis, Costas A., Bian, Zhiguo, Shotwell, J. Brad, Yadav, Viveka Nand, Koschmann, Carl, Chinnaiyan, Arul M., Blüml, Stefan, Judkins, Alexander R., Venneti, Sriram
Published in Cancer cell (14.09.2020)
Published in Cancer cell (14.09.2020)
Get full text
Journal Article
Targeting SWI/SNF ATPases in H3.3K27M diffuse intrinsic pontine gliomas
Mota, Mateus, Sweha, Stefan R, Pun, Matt, Natarajan, Siva Kumar, Ding, Yujie, Chung, Chan, Hawes, Debra, Yang, Fusheng, Judkins, Alexander R, Samajdar, Susanta, Cao, Xuhong, Xiao, Lanbo, Parolia, Abhijit, Chinnaiyan, Arul M, Venneti, Sriram
Published in Proceedings of the National Academy of Sciences - PNAS (02.05.2023)
Published in Proceedings of the National Academy of Sciences - PNAS (02.05.2023)
Get full text
Journal Article
Therapeutic targeting of differentiation-state dependent metabolic vulnerabilities in diffuse midline glioma
Mbah, Nneka E., Myers, Amy L., Sajjakulnukit, Peter, Chung, Chan, Thompson, Joyce K., Hong, Hanna S., Giza, Heather, Dang, Derek, Nwosu, Zeribe C., Shan, Mengrou, Sweha, Stefan R., Maydan, Daniella D., Chen, Brandon, Zhang, Li, Magnuson, Brian, Zhu, Zirui, Radyk, Megan, Lavoie, Brooke, Yadav, Viveka Nand, Koo, Imhoi, Patterson, Andrew D., Wahl, Daniel R., Franchi, Luigi, Agnihotri, Sameer, Koschmann, Carl J., Venneti, Sriram, Lyssiotis, Costas A.
Published in Nature communications (17.10.2024)
Published in Nature communications (17.10.2024)
Get full text
Journal Article
Epigenetically defined therapeutic targeting in H3.3G34R/V high-grade gliomas
Sweha, Stefan R, Chung, Chan, Natarajan, Siva Kumar, Panwalkar, Pooja, Pun, Matthew, Ghali, Amer, Bayliss, Jill, Pratt, Drew, Shankar, Anand, Ravikumar, Visweswaran, Rao, Arvind, Cieslik, Marcin, Wilder-Romans, Kari, Scott, Andrew J, Wahl, Daniel R, Jessa, Selin, Kleinman, Claudia L, Jabado, Nada, Mackay, Alan, Jones, Chris, Martinez, Daniel, Santi, Mariarita, Judkins, Alexander R, Yadav, Viveka Nand, Qin, Tingting, Phoenix, Timothy N, Koschmann, Carl J, Baker, Suzanne J, Chinnaiyan, Arul M, Venneti, Sriram
Published in Science translational medicine (13.10.2021)
Published in Science translational medicine (13.10.2021)
Get more information
Journal Article
Molecular biomarkers predictive of sertraline treatment response in young children with fragile X syndrome
AlOlaby, Reem Rafik, Sweha, Stefan R, Silva, Marisol, Durbin-Johnson, Blythe, Yrigollen, Carolyn M, Pretto, Dalyir, Hagerman, Randi J, Tassone, Flora
Published in Brain & development (Tokyo. 1979) (01.06.2017)
Published in Brain & development (Tokyo. 1979) (01.06.2017)
Get full text
Journal Article
Clinical and molecular correlates in fragile X premutation females
Jiraanont, Poonnada, Sweha, Stefan R., AlOlaby, Reem R., Silva, Marisol, Tang, Hiu-Tung, Durbin-Johnson, Blythe, Schneider, Andrea, Espinal, Glenda M., Hagerman, Paul J., Rivera, Susan M., Hessl, David, Hagerman, Randi J., Chutabhakdikul, Nuanchan, Tassone, Flora
Published in eNeurologicalSci (01.06.2017)
Published in eNeurologicalSci (01.06.2017)
Get full text
Journal Article
Therapeutic targeting of prenatal pontine ID1 signaling in diffuse midline glioma
Messinger, Dana, Harris, Micah K, Cummings, Jessica R, Thomas, Chase, Yang, Tao, Sweha, Stefan R, Woo, Rinette, Siddaway, Robert, Burkert, Martin, Stallard, Stefanie, Qin, Tingting, Mullan, Brendan, Siada, Ruby, Ravindran, Ramya, Niculcea, Michael, Dowling, Abigail R, Bradin, Joshua, Ginn, Kevin F, Gener, Melissa A H, Dorris, Kathleen, Vitanza, Nicholas A, Schmidt, Susanne V, Spitzer, Jasper, Li, Jiang, Filbin, Mariella G, Cao, Xuhong, Castro, Maria G, Lowenstein, Pedro R, Mody, Rajen, Chinnaiyan, Arul, Desprez, Pierre-Yves, McAllister, Sean, Dun, Matthew D, Hawkins, Cynthia, Waszak, Sebastian M, Venneti, Sriram, Koschmann, Carl, Yadav, Viveka Nand
Published in Neuro-oncology (Charlottesville, Va.) (05.01.2023)
Published in Neuro-oncology (Charlottesville, Va.) (05.01.2023)
Get full text
Journal Article
Clinical Efficacy of ONC201 in H3K27M-Mutant Diffuse Midline Gliomas Is Driven by Disruption of Integrated Metabolic and Epigenetic Pathways
Venneti, Sriram, Kawakibi, Abed Rahman, Ji, Sunjong, Waszak, Sebastian M, Sweha, Stefan R, Mota, Mateus, Pun, Matthew, Deogharkar, Akash, Chung, Chan, Tarapore, Rohinton S, Ramage, Samuel, Chi, Andrew, Wen, Patrick Y, Arrillaga-Romany, Isabel, Batchelor, Tracy T, Butowski, Nicholas A, Sumrall, Ashley, Shonka, Nicole, Harrison, Rebecca A, de Groot, John, Mehta, Minesh, Hall, Matthew D, Daghistani, Doured, Cloughesy, Timothy F, Ellingson, Benjamin M, Beccaria, Kevin, Varlet, Pascale, Kim, Michelle M, Umemura, Yoshie, Garton, Hugh, Franson, Andrea, Schwartz, Jonathan, Jain, Rajan, Kachman, Maureen, Baum, Heidi, Burant, Charles F, Mottl, Sophie L, Cartaxo, Rodrigo T, John, Vishal, Messinger, Dana, Qin, Tingting, Peterson, Erik, Sajjakulnukit, Peter, Ravi, Karthik, Waugh, Alyssa, Walling, Dustin, Ding, Yujie, Xia, Ziyun, Schwendeman, Anna, Hawes, Debra, Yang, Fusheng, Judkins, Alexander R, Wahl, Daniel, Lyssiotis, Costas A, de la Nava, Daniel, Alonso, Marta M, Eze, Augustine, Spitzer, Jasper, Schmidt, Susanne V, Duchatel, Ryan J, Dun, Matthew D, Cain, Jason E, Jiang, Li, Stopka, Sylwia A, Baquer, Gerard, Regan, Michael S, Filbin, Mariella G, Agar, Nathalie Y R, Zhao, Lili, Kumar-Sinha, Chandan, Mody, Rajen, Chinnaiyan, Arul, Kurokawa, Ryo, Pratt, Drew, Yadav, Viveka N, Grill, Jacques, Kline, Cassie, Mueller, Sabine, Resnick, Adam, Nazarian, Javad, Allen, Joshua E, Odia, Yazmin, Gardner, Sharon L, Koschmann, Carl
Published in Cancer discovery (01.11.2023)
Published in Cancer discovery (01.11.2023)
Get full text
Journal Article