Comparison of toxicogenomics and traditional approaches to inform mode of action and points of departure in human health risk assessment of benzo[a]pyrene in drinking water
Moffat, Ivy, Chepelev, Nikolai L., Labib, Sarah, Bourdon-Lacombe, Julie, Kuo, Byron, Buick, Julie K., Lemieux, France, Williams, Andrew, Halappanavar, Sabina, Malik, Amal I, Luijten, Mirjam, Aubrecht, Jiri, Hyduke, Daniel R., Fornace, Albert J., Swartz, Carol D., Recio, Leslie, Yauk, Carole L.
Published in Critical reviews in toxicology (01.01.2015)
Published in Critical reviews in toxicology (01.01.2015)
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Flow cytometric micronucleus assay and TGx-DDI transcriptomic biomarker analysis of ten genotoxic and non-genotoxic chemicals in human HepaRG™ cells
Buick, Julie K, Williams, Andrew, Gagné, Rémi, Swartz, Carol D, Recio, Leslie, Ferguson, Stephen S, Yauk, Carole L
Published in Genes and environment (04.02.2020)
Published in Genes and environment (04.02.2020)
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Application of the TGx-28.65 transcriptomic biomarker to classify genotoxic and non-genotoxic chemicals in human TK6 cells in the presence of rat liver S9
Yauk, Carole L., Buick, Julie K., Williams, Andrew, Swartz, Carol D., Recio, Leslie, Li, Heng-Hong, Fornace Jr, Albert J., Thomson, Errol M., Aubrecht, Jiri
Published in Environmental and molecular mutagenesis (01.05.2016)
Published in Environmental and molecular mutagenesis (01.05.2016)
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A Modern Genotoxicity Testing Paradigm: Integration of the High-Throughput CometChip® and the TGx-DDI Transcriptomic Biomarker in Human HepaRG™ Cell Cultures
Buick, Julie K., Williams, Andrew, Meier, Matthew J., Swartz, Carol D., Recio, Leslie, Gagné, Rémi, Ferguson, Stephen S., Engelward, Bevin P., Yauk, Carole L.
Published in Frontiers in public health (18.08.2021)
Published in Frontiers in public health (18.08.2021)
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A predictive toxicogenomics signature to classify genotoxic versus non-genotoxic chemicals in human TK6 cells
Williams, Andrew, Buick, Julie K., Moffat, Ivy, Swartz, Carol D., Recio, Leslie, Hyduke, Daniel R., Li, Heng-Hong, Fornace, Albert J., Aubrecht, Jiri, Yauk, Carole L.
Published in Data in brief (01.12.2015)
Published in Data in brief (01.12.2015)
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Human uterine leiomyoma-derived fibroblasts stimulate uterine leiomyoma cell proliferation and collagen type I production, and activate RTKs and TGF beta receptor signaling in coculture
Moore, Alicia B, Yu, Linda, Swartz, Carol D, Zheng, Xaiolin, Wang, Lu, Castro, Lysandra, Kissling, Grace E, Walmer, David K, Robboy, Stanley J, Dixon, Darlene
Published in Cell communication and signaling (10.06.2010)
Published in Cell communication and signaling (10.06.2010)
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Immortalization of Human Uterine Leiomyoma and Myometrial Cell Lines After Induction of Telomerase Activity: Molecular and Phenotypic Characteristics
Carney, Sara A, Tahara, Hidetoshi, Swartz, Carol D, Risinger, John I, He, Hong, Moore, Alicia B, Haseman, Joseph K, Barrett, J Carl, Dixon, Darlene
Published in Laboratory investigation (01.06.2002)
Published in Laboratory investigation (01.06.2002)
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Error-corrected duplex sequencing enables direct detection and quantification of mutations in human TK6 cells with strong inter-laboratory consistency
Cho, Eunnara, Swartz, Carol D., Williams, Andrew, V. Rivas, Miriam, Recio, Leslie, Witt, Kristine L., Schmidt, Elizabeth K., Yaplee, Jeffry, Smith, Thomas H., Van, Phu, Lo, Fang Yin, Valentine, Charles C., Salk, Jesse J., Marchetti, Francesco, Smith-Roe, Stephanie L., Yauk, Carole L.
Published in Mutation research. Genetic toxicology and environmental mutagenesis (01.07.2023)
Published in Mutation research. Genetic toxicology and environmental mutagenesis (01.07.2023)
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Evaluation of the herbicide glyphosate, (aminomethyl)phosphonic acid, and glyphosate‐based formulations for genotoxic activity using in vitro assays
Smith‐Roe, Stephanie L., Swartz, Carol D., Rashid, Asma, Christy, Nicholas C., Sly, Jamie E., Chang, Xiaoqing, Sipes, Nisha S., Shockley, Keith R., Harris, Shawn F., McBride, Sandra J., Larson, Gary J., Collins, Bradley J., Mutlu, Esra, Witt, Kristine L.
Published in Environmental and molecular mutagenesis (01.04.2023)
Published in Environmental and molecular mutagenesis (01.04.2023)
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Toxicogenomic analysis incorporating operon-transcriptional coupling and toxicant concentration-expression response: analysis of MX-treated Salmonella
Ward, William O, Swartz, Carol D, Porwollik, Steffen, Warren, Sarah H, Hanley, Nancy M, Knapp, Geremy W, McClelland, Michael, DeMarini, David M
Published in BMC bioinformatics (09.10.2007)
Published in BMC bioinformatics (09.10.2007)
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Integration of metabolic activation with a predictive toxicogenomics signature to classify genotoxic versus nongenotoxic chemicals in human TK6 cells
Buick, Julie K., Moffat, Ivy, Williams, Andrew, Swartz, Carol D., Recio, Leslie, Hyduke, Daniel R., Li, Heng-Hong, Fornace Jr, Albert J., Aubrecht, Jiri, Yauk, Carole L.
Published in Environmental and molecular mutagenesis (01.07.2015)
Published in Environmental and molecular mutagenesis (01.07.2015)
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Integrated in silico and in vitro genotoxicity assessment of thirteen data-poor substances
Tran, Yen K., Buick, Julie K., Keir, Jennifer L.A., Williams, Andrew, Swartz, Carol D., Recio, Leslie, White, Paul A., Lambert, Iain B., Yauk, Carole L.
Published in Regulatory toxicology and pharmacology (01.10.2019)
Published in Regulatory toxicology and pharmacology (01.10.2019)
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Black cohosh extracts and powders induce micronuclei, a biomarker of genetic damage, in human cells
Smith‐Roe, Stephanie L., Swartz, Carol D., Shepard, Kim G., Bryce, Steven M., Dertinger, Stephen D., Waidyanatha, Suramya, Kissling, Grace E., Auerbach, Scott S., Witt, Kristine L., Zeiger, E.
Published in Environmental and molecular mutagenesis (01.06.2018)
Published in Environmental and molecular mutagenesis (01.06.2018)
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Journal Article
Using the HepaCometChip Assay for Broad‐Spectrum DNA Damage Analysis
Owiti, Norah A., Kaushal, Simran, Martin, Lincoln, Sly, Jamie, Swartz, Carol D., Fowler, Jasmine, Corrigan, Joshua J., Recio, Les, Engelward, Bevin P.
Published in Current protocols (01.09.2022)
Published in Current protocols (01.09.2022)
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Differential expression of receptor tyrosine kinases (RTKs) and IGF-I pathway activation in human uterine leiomyomas
Yu, Linda, Saile, Katrin, Swartz, Carol D, He, Hong, Zheng, Xiaolin, Kissling, Grace E, Di, Xudong, Lucas, Shantelle, Robboy, Stanley J, Dixon, Darlene
Published in Molecular medicine (Cambridge, Mass.) (01.05.2008)
Published in Molecular medicine (Cambridge, Mass.) (01.05.2008)
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Journal Article
Integration of the TGx-28.65 genomic biomarker with the flow cytometry micronucleus test to assess the genotoxicity of disperse orange and 1,2,4-benzenetriol in human TK6 cells
Buick, Julie K, Williams, Andrew, Kuo, Byron, Wills, John W, Swartz, Carol D, Recio, Leslie, Li, Heng-Hong, Fornace, Jr, Albert J, Aubrecht, Jiri, Yauk, Carole L
Published in Mutation research (01.12.2017)
Published in Mutation research (01.12.2017)
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Mutagenicity, stable DNA adducts, and abasic sites induced in Salmonella by phenanthro[3,4-b]- and phenanthro[4,3-b]thiophenes, sulfur analogs of benzo[c]phenanthrene
Swartz, Carol D, King, Leon C, Nesnow, Stephen, Umbach, David M, Kumar, Subodh, Sikka, Harish, Demarini, David M
Published in Mutation research (10.02.2009)
Published in Mutation research (10.02.2009)
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Association of race, age and body mass index with gross pathology of uterine fibroids
Moore, Alicia B, Flake, Gordon P, Swartz, Carol D, Heartwell, Glenn, Cousins, Deborah, Haseman, Joseph K, Kissling, Grace E, Sidawy, Mary K, Dixon, Darlene
Published in Journal of reproductive medicine (01.02.2008)
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Published in Journal of reproductive medicine (01.02.2008)
Journal Article
Mutagen structure and transcriptional response: Induction of distinct transcriptional profiles in Salmonella TA100 by the drinking-water mutagen MX and its homologues
Ward, William O, Swartz, Carol D, Hanley, Nancy M, Whitaker, John W, Franzén, Robert, DeMarini, David M
Published in Environmental and molecular mutagenesis (2010)
Published in Environmental and molecular mutagenesis (2010)
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