Discovery of {4-[4,9-bis(ethyloxy)-1-oxo-1,3-dihydro-2H-benzo[f]isoindol-2-yl]-2-fluorophenyl}acetic acid (GSK726701A), a novel EP4 receptor partial agonist for the treatment of pain
Healy, Mark P., Allan, Amanda C., Bailey, Kristin, Billinton, Andy, Chessell, Iain P., Clayton, Nicholas M., Giblin, Gerard M.P., Kay, Melanie A., Khaznadar, Tarik, Michel, Anton D., Naylor, Alan, Price, Helen, Spalding, David J., Stevens, David A., Swarbrick, Martin E., Wilson, Alexander W.
Published in Bioorganic & medicinal chemistry letters (01.06.2018)
Published in Bioorganic & medicinal chemistry letters (01.06.2018)
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Journal Article
Probabilistic longevity estimate for the Lusi mud volcano, East Java
Davies, Richard J, Mathias, Simon A, Swarbrick, Richard E, Tingay, Mark J
Published in Journal of the Geological Society (01.03.2011)
Published in Journal of the Geological Society (01.03.2011)
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Further observations on LKB1/STK11 status and cancer risk in Peutz-Jeghers syndrome
Lim, W, Hearle, N, Shah, B, Murday, V, Hodgson, S V, Lucassen, A, Eccles, D, Talbot, I, Neale, K, Lim, A G, O'Donohue, J, Donaldson, A, Macdonald, R C, Young, I D, Robinson, M H, Lee, P W R, Stoodley, B J, Tomlinson, I, Alderson, D, Holbrook, A G, Vyas, S, Swarbrick, E T, Lewis, A A M, Phillips, R K S, Houlston, R S
Published in British journal of cancer (21.07.2003)
Published in British journal of cancer (21.07.2003)
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Downstaging of colorectal cancer by the national bowel cancer screening programme in England: first round data from the first centre
Ellul, P., Fogden, E., Simpson, C. L., Nickerson, C. L. R., Mckaig, B. C., Swarbrick, E. T., Veitch, A. M.
Published in Colorectal disease (01.05.2010)
Published in Colorectal disease (01.05.2010)
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Inflammatory bowel disease and domestic hygiene in infancy
Gent, A.E., Hellier, M.D., Grace, R.H., Swarbrick, E.T., Coggon, D.
Published in The Lancet (British edition) (26.03.1994)
Published in The Lancet (British edition) (26.03.1994)
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Identifying and managing patients at low risk of bowel cancer in general practice
Thompson, M R, Heath, I, Ellis, B G, Swarbrick, E T, Wood, L Faulds, Atkin, W S
Published in BMJ (02.08.2003)
Published in BMJ (02.08.2003)
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Randomised controlled trial of azathioprine withdrawal in ulcerative colitis
Hawthorne, A. B., Logan, R. F., Hawkey, C. J., Foster, P. N., Axon, A. T., Swarbrick, E. T., Scott, B. B., Lennard-Jones, J. E.
Published in BMJ (04.07.1992)
Published in BMJ (04.07.1992)
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Once daily Asacol
Hawthorne, A B, Stenson, R, Gillespie, D, Swarbrick, E T, Dhar, A, Kapur, K C, Hood, K, Probert, C S
Published in Gut (01.04.2011)
Published in Gut (01.04.2011)
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Fragment-based hit identification: thinking in 3D
Morley, Andrew D., Pugliese, Angelo, Birchall, Kristian, Bower, Justin, Brennan, Paul, Brown, Nathan, Chapman, Tim, Drysdale, Martin, Gilbert, Ian H., Hoelder, Swen, Jordan, Allan, Ley, Steven V., Merritt, Andy, Miller, David, Swarbrick, Martin E., Wyatt, Paul G.
Published in Drug discovery today (01.12.2013)
Published in Drug discovery today (01.12.2013)
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MNK Inhibition Sensitizes KRAS -Mutant Colorectal Cancer to mTORC1 Inhibition by Reducing eIF4E Phosphorylation and c-MYC Expression
Knight, John R P, Alexandrou, Constantinos, Skalka, George L, Vlahov, Nikola, Pennel, Kathryn, Officer, Leah, Teodosio, Ana, Kanellos, Georgios, Gay, David M, May-Wilson, Sebastian, Smith, Ewan M, Najumudeen, Arafath K, Gilroy, Kathryn, Ridgway, Rachel A, Flanagan, Dustin J, Smith, Rachael C L, McDonald, Laura, MacKay, Craig, Cheasty, Anne, McArthur, Kerri, Stanway, Emma, Leach, Joshua D, Jackstadt, Rene, Waldron, Joseph A, Campbell, Andrew D, Vlachogiannis, Georgios, Valeri, Nicola, Haigis, Kevin M, Sonenberg, Nahum, Proud, Christopher G, Jones, Neil P, Swarbrick, Martin E, McKinnon, Heather J, Faller, William J, Le Quesne, John, Edwards, Joanne, Willis, Anne E, Bushell, Martin, Sansom, Owen J
Published in Cancer discovery (01.05.2021)
Published in Cancer discovery (01.05.2021)
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Discovery, Characterization, and Structure-Based Optimization of Small-Molecule In Vitro and In Vivo Probes for Human DNA Polymerase Theta
Stockley, Martin L., Ferdinand, Amanda, Benedetti, Giovanni, Blencowe, Peter, Boyd, Susan M., Calder, Mat, Charles, Mark D., Edwardes, Lucy V., Ekwuru, Tennyson, Finch, Harry, Galbiati, Alessandro, Geo, Lerin, Grande, Diego, Grinkevich, Vera, Holliday, Nicholas D., Krajewski, Wojciech W., MacDonald, Ellen, Majithiya, Jayesh B., McCarron, Hollie, McWhirter, Claire L., Patel, Viral, Pedder, Chris, Rajendra, Eeson, Ranzani, Marco, Rigoreau, Laurent J. M., Robinson, Helen M. R., Schaedler, Theresia, Sirina, Julija, Smith, Graeme C. M., Swarbrick, Martin E., Turnbull, Andrew P., Willis, Simon, Heald, Robert A.
Published in Journal of medicinal chemistry (27.10.2022)
Published in Journal of medicinal chemistry (27.10.2022)
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