Eeyarestatin Compounds Selectively Enhance Sec61-Mediated Ca2+ Leakage from the Endoplasmic Reticulum
Gamayun, Igor, O'Keefe, Sarah, Pick, Tillman, Klein, Marie-Christine, Nguyen, Duy, McKibbin, Craig, Piacenti, Michela, Williams, Helen M., Flitsch, Sabine L., Whitehead, Roger C., Swanton, Eileithyia, Helms, Volkhard, High, Stephen, Zimmermann, Richard, Cavalié, Adolfo
Published in Cell chemical biology (18.04.2019)
Published in Cell chemical biology (18.04.2019)
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Increased intracellular proteolysis reduces disease severity in an ER stress-associated dwarfism
Mullan, Lorna A, Mularczyk, Ewa J, Kung, Louise H, Forouhan, Mitra, Wragg, Jordan Ma, Goodacre, Royston, Bateman, John F, Swanton, Eileithyia, Briggs, Michael D, Boot-Handford, Raymond P
Published in The Journal of clinical investigation (01.10.2017)
Published in The Journal of clinical investigation (01.10.2017)
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The Plasma Membrane Calcium Pump in Pancreatic Cancer Cells Exhibiting the Warburg Effect Relies on Glycolytic ATP
James, Andrew D., Patel, Waseema, Butt, Zohra, Adiamah, Magretta, Dakhel, Raga, Latif, Ayse, Uggenti, Carolina, Swanton, Eileithyia, Imamura, Hiromi, Siriwardena, Ajith K., Bruce, Jason I.E.
Published in The Journal of biological chemistry (09.10.2015)
Published in The Journal of biological chemistry (09.10.2015)
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Journal Article
Eeyarestatin I inhibits Sec61-mediated protein translocation at the endoplasmic reticulum
Cross, Benedict C.S, McKibbin, Craig, Callan, Anna C, Roboti, Peristera, Piacenti, Michela, Rabu, Catherine, Wilson, Cornelia M, Whitehead, Roger, Flitsch, Sabine L, Pool, Martin R, High, Stephen, Swanton, Eileithyia
Published in Journal of cell science (01.12.2009)
Published in Journal of cell science (01.12.2009)
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Restoration of mutant bestrophin-1 expression, localisation and function in a polarised epithelial cell model
Uggenti, Carolina, Briant, Kit, Streit, Anne-Kathrin, Thomson, Steven, Koay, Yee Hui, Baines, Richard A, Swanton, Eileithyia, Manson, Forbes D
Published in Disease models & mechanisms (01.11.2016)
Published in Disease models & mechanisms (01.11.2016)
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Paracrine signal emanating from stressed cardiomyocytes aggravates inflammatory microenvironment in diabetic cardiomyopathy
Kaur, Namrita, Ruiz-Velasco, Andrea, Raja, Rida, Howell, Gareth, Miller, Jessica M., Abouleisa, Riham R.E., Ou, Qinghui, Mace, Kimberly, Hille, Susanne S., Frey, Norbert, Binder, Pablo, Smith, Craig P., Fachim, Helene, Soran, Handrean, Swanton, Eileithyia, Mohamed, Tamer M.A., Müller, Oliver J., Wang, Xin, Chernoff, Jonathan, Cartwright, Elizabeth J., Liu, Wei
Published in iScience (18.03.2022)
Published in iScience (18.03.2022)
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Eeyarestatin 1 interferes with both retrograde and anterograde intracellular trafficking pathways
Aletrari, Mina-Olga, McKibbin, Craig, Williams, Helen, Pawar, Vidya, Pietroni, Paola, Lord, J Michael, Flitsch, Sabine L, Whitehead, Roger, Swanton, Eileithyia, High, Stephen, Spooner, Robert A
Published in PloS one (25.07.2011)
Published in PloS one (25.07.2011)
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Elevation of proteasomal substrate levels sensitizes cells to apoptosis induced by inhibition of proteasomal deubiquitinases
Sun, Chao, Roboti, Peristera, Puumalainen, Marjo-Riitta, Fryknäs, Mårten, Wang, Xin, D'Arcy, Padraig, Hult, Malin, High, Stephen, Linder, Stig, Swanton, Eileithyia
Published in PloS one (2014)
Published in PloS one (2014)
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Biosynthesis of the dystonia-associated AAA+ ATPase torsinA at the endoplasmic reticulum
Callan, Anna C, Bunning, Sandra, Jones, Owen T, High, Stephen, Swanton, Eileithyia
Published in Biochemical journal (15.01.2007)
Published in Biochemical journal (15.01.2007)
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Disease-Associated Mutations Cause Premature Oligomerization of Myelin Proteolipid Protein in the Endoplasmic Reticulum
Swanton, Eileithyia, Holland, Andrew, High, Stephen, Woodman, Philip, Schekman, Randy
Published in Proceedings of the National Academy of Sciences - PNAS (22.03.2005)
Published in Proceedings of the National Academy of Sciences - PNAS (22.03.2005)
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Deubiquitinases Regulate the Activity of Caspase-1 and Interleukin-1β Secretion via Assembly of the Inflammasome
Lopez-Castejon, Gloria, Luheshi, Nadia M., Compan, Vincent, High, Stephen, Whitehead, Roger C., Flitsch, Sabine, Kirov, Aleksandr, Prudovsky, Igor, Swanton, Eileithyia, Brough, David
Published in The Journal of biological chemistry (25.01.2013)
Published in The Journal of biological chemistry (25.01.2013)
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Pak2 as a Novel Therapeutic Target for Cardioprotective Endoplasmic Reticulum Stress Response
Binder, Pablo, Wang, Shunyao, Radu, Maria, Zin, Min, Collins, Lucy, Khan, Saba, Li, Yatong, Sekeres, Karolina, Humphreys, Neil, Swanton, Eileithyia, Reid, Adam, Pu, Fay, Oceandy, Delvac, Guan, Kaomei, Hille, Susanne S, Frey, Norbert, Müller, Oliver J, Cartwright, Elizabeth J, Chernoff, Jonathan, Wang, Xin, Liu, Wei
Published in Circulation research (01.03.2019)
Published in Circulation research (01.03.2019)
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Eeyarestatin 24 impairs SecYEG‐dependent protein trafficking and inhibits growth of clinically relevant pathogens
Steenhuis, Maurice, Koningstein, Gregory M., Oswald, Julia, Pick, Tillman, O’Keefe, Sarah, Koch, Hans‐Georg, Cavalié, Adolfo, Whitehead, Roger C., Swanton, Eileithyia, High, Stephen, Luirink, Joen
Published in Molecular microbiology (01.01.2021)
Published in Molecular microbiology (01.01.2021)
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