Triculamin: An Unusual Lasso Peptide with Potent Antimycobacterial Activity
Andersen, Frederikke D., Pedersen, Katja D., Wilkens Juhl, Dennis, Mygind, Tobias, Chopin, Paul, B. Svenningsen, Esben, Poulsen, Thomas B., Braad Lund, Marie, Schramm, Andreas, Gotfredsen, Charlotte H., Tørring, Thomas
Published in Journal of natural products (Washington, D.C.) (24.06.2022)
Published in Journal of natural products (Washington, D.C.) (24.06.2022)
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Journal Article
Expanding the antibacterial selectivity of polyether ionophore antibiotics through diversity-focused semisynthesis
Lin, Shaoquan, Liu, Han, Svenningsen, Esben B., Wollesen, Malene, Jacobsen, Kristian M., Andersen, Frederikke D., Moyano-Villameriel, Jaime, Pedersen, Christine N., Nørby, Peter, Tørring, Thomas, Poulsen, Thomas B.
Published in Nature chemistry (01.01.2021)
Published in Nature chemistry (01.01.2021)
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Journal Article
Ionophore antibiotic X-206 is a potent inhibitor of SARS-CoV-2 infection in vitro
Svenningsen, Esben B., Thyrsted, Jacob, Blay-Cadanet, Julia, Liu, Han, Lin, Shaoquan, Moyano-Villameriel, Jaime, Olagnier, David, Idorn, Manja, Paludan, Søren R., Holm, Christian K., Poulsen, Thomas B.
Published in Antiviral research (01.01.2021)
Published in Antiviral research (01.01.2021)
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The synthetic triterpenoids CDDO-TFEA and CDDO-Me, but not CDDO, promote nuclear exclusion of BACH1 impairing its activity
Casares, Laura, Moreno, Rita, Ali, Kevin X., Higgins, Maureen, Dayalan Naidu, Sharadha, Neill, Graham, Cassin, Lena, Kiib, Anders E., Svenningsen, Esben B., Minassi, Alberto, Honda, Tadashi, Poulsen, Thomas B., Wiel, Clotilde, Sayin, Volkan I., Dinkova-Kostova, Albena T., Olagnier, David, de la Vega, Laureano
Published in Redox biology (01.05.2022)
Published in Redox biology (01.05.2022)
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Establishing cell painting in a smaller chemical biology lab – A report from the frontier
Svenningsen, Esben B., Poulsen, Thomas B.
Published in Bioorganic & medicinal chemistry (15.06.2019)
Published in Bioorganic & medicinal chemistry (15.06.2019)
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Journal Article
α‐Lactam Electrophiles for Covalent Chemical Biology
Mahía, Alejandro, Kiib, Anders E., Nisavic, Marija, Svenningsen, Esben B., Palmfeldt, Johan, Poulsen, Thomas B.
Published in Angewandte Chemie International Edition (26.06.2023)
Published in Angewandte Chemie International Edition (26.06.2023)
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Journal Article
Enantioselective Synthesis of α‐Quaternary Isochromanes by Oxidative Aminocatalysis and Gold Catalysis
Waser, Philipp, Faghtmann, Jonas, Gil‐Ordóñez, Marta, Kristensen, Anne, Svenningsen, Esben B., Poulsen, Thomas B., Jørgensen, Karl Anker
Published in Chemistry : a European journal (05.07.2024)
Published in Chemistry : a European journal (05.07.2024)
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Journal Article
Organocatalytic Asymmetric Multicomponent Cascade Reaction for the Synthesis of Contiguously Substituted Tetrahydronaphthols
Liu, Yidong, Izzo, Joseph A, McLeod, David, Ričko, Sebastijan, Svenningsen, Esben B, Poulsen, Thomas B, Jørgensen, Karl Anker
Published in Journal of the American Chemical Society (02.06.2021)
Published in Journal of the American Chemical Society (02.06.2021)
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Journal Article
Macrodiolide Diversification Reveals Broad Immunosuppressive Activity That Impairs the cGAS‐STING Pathway
Liu, Han, Ottosen, Rasmus N., Jennet, Kira M., Svenningsen, Esben B., Kristensen, Tobias F., Biltoft, Mette, Jakobsen, Martin R., Poulsen, Thomas B.
Published in Angewandte Chemie International Edition (16.08.2021)
Published in Angewandte Chemie International Edition (16.08.2021)
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Journal Article
The Biological Activities of Polyether Ionophore Antibiotic Routiennocin is Independent of Absolute Stereochemistry
Borcher Møller, Søren Lau, Rasmussen, Michelle H., Li, Jun, Svenningsen, Esben B., Wørmer, Gustav J., Tørring, Thomas, Poulsen, Thomas B.
Published in Chembiochem : a European journal of chemical biology (02.04.2024)
Published in Chembiochem : a European journal of chemical biology (02.04.2024)
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Journal Article
Stendomycin and Pantomycin Are Identical Natural Products: Preparation of a Functionalized Bioactive Analogue
Villadsen, Nikolaj L, Hansen, Bente K, Svenningsen, Esben B, Jørgensen, Katrine H, Tørring, Thomas, Poulsen, Thomas B
Published in Journal of organic chemistry (06.07.2018)
Published in Journal of organic chemistry (06.07.2018)
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Journal Article
α‐Lactam Electrophiles for Covalent Chemical Biology
Mahía, Alejandro, Kiib, Anders E., Nisavic, Marija, Svenningsen, Esben B., Palmfeldt, Johan, Poulsen, Thomas B.
Published in Angewandte Chemie (26.06.2023)
Published in Angewandte Chemie (26.06.2023)
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Journal Article
Structure and Function of the Bacterial Protein Toxin Phenomycin
Hansen, Bente K., Larsen, Camilla K., Nielsen, Jakob T., Svenningsen, Esben B., Van, Lan B., Jacobsen, Kristian M., Bjerring, Morten, Flygaard, Rasmus K., Jenner, Lasse B., Nejsum, Lene N., Brodersen, Ditlev E., Mulder, Frans A.A., Tørring, Thomas, Poulsen, Thomas B.
Published in Structure (London) (05.05.2020)
Published in Structure (London) (05.05.2020)
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Journal Article
The covalent reactivity of functionalized 5-hydroxy-butyrolactams is the basis for targeting of fatty acid binding protein 5 (FABP5) by the neurotrophic agent MT-21
Svenningsen, Esben B., Ottosen, Rasmus N., Jørgensen, Katrine H., Nisavic, Marija, Larsen, Camilla K., Hansen, Bente K., Wang, Yong, Lindorff-Larsen, Kresten, Tørring, Thomas, Hacker, Stephan M., Palmfeldt, Johan, Poulsen, Thomas B.
Published in RSC chemical biology (05.10.2022)
Published in RSC chemical biology (05.10.2022)
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Journal Article
Macrodiolide Diversification Reveals Broad Immunosuppressive Activity That Impairs the cGAS‐STING Pathway
Liu, Han, Ottosen, Rasmus N., Jennet, Kira M., Svenningsen, Esben B., Kristensen, Tobias F., Biltoft, Mette, Jakobsen, Martin R., Poulsen, Thomas B.
Published in Angewandte Chemie (16.08.2021)
Published in Angewandte Chemie (16.08.2021)
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Journal Article
SARS-CoV2-mediated suppression of NRF2-signaling reveals potent antiviral and anti-inflammatory activity of 4-octyl-itaconate and dimethyl fumarate
Olagnier, David, Farahani, Ensieh, Thyrsted, Jacob, Blay-Cadanet, Julia, Herengt, Angela, Idorn, Manja, Hait, Alon, Hernaez, Bruno, Knudsen, Alice, Iversen, Marie Beck, Schilling, Mirjam, Jørgensen, Sofie E., Thomsen, Michelle, Reinert, Line S., Lappe, Michael, Hoang, Huy-Dung, Gilchrist, Victoria H., Hansen, Anne Louise, Ottosen, Rasmus, Nielsen, Camilla G., Møller, Charlotte, van der Horst, Demi, Peri, Suraj, Balachandran, Siddharth, Huang, Jinrong, Jakobsen, Martin, Svenningsen, Esben B., Poulsen, Thomas B., Bartsch, Lydia, Thielke, Anne L., Luo, Yonglun, Alain, Tommy, Rehwinkel, Jan, Alcamí, Antonio, Hiscott, John, Mogensen, Trine H., Paludan, Søren R., Holm, Christian K.
Published in Nature communications (02.10.2020)
Published in Nature communications (02.10.2020)
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Journal Article
Expanding the antibacterial selectivity of polyether ionophore antibiotics through diversity focused semi-synthesis
Lin, Shaoquan, Liu, Han, Svenningsen, Esben B., Wollesen, Malene, Jacobsen, Kristian M., Andersen, Frederikke D., Villameriel, Jaime M., Pedersen, Christine N., Nørby, Peter, Tørring, Thomas, Poulsen, Thomas B.
Published in Nature chemistry (22.12.2020)
Published in Nature chemistry (22.12.2020)
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Journal Article
Octyl itaconate enhances VSVΔ51 oncolytic virotherapy by multitarget inhibition of antiviral and inflammatory pathways
Kurmasheva, Naziia, Said, Aida, Wong, Boaz, Kinderman, Priscilla, Han, Xiaoying, Rahimic, Anna H. F., Kress, Alena, Carter-Timofte, Madalina E., Holm, Emilia, van der Horst, Demi, Kollmann, Christoph F., Liu, Zhenlong, Wang, Chen, Hoang, Huy-Dung, Kovalenko, Elina, Chrysopoulou, Maria, Twayana, Krishna Sundar, Ottosen, Rasmus N., Svenningsen, Esben B., Begnini, Fabio, Kiib, Anders E., Kromm, Florian E. H., Weiss, Hauke J., Di Carlo, Daniele, Muscolini, Michela, Higgins, Maureen, van der Heijden, Mirte, Bardoul, Angelina, Tong, Tong, Ozsvar, Attila, Hou, Wen-Hsien, Schack, Vivien R., Holm, Christian K., Zheng, Yunan, Ruzek, Melanie, Kalucka, Joanna, de la Vega, Laureano, Elgaher, Walid A. M., Korshoej, Anders R., Lin, Rongtuan, Hiscott, John, Poulsen, Thomas B., O’Neill, Luke A., Roy, Dominic G., Rinschen, Markus M., van Montfoort, Nadine, Diallo, Jean-Simon, Farin, Henner F., Alain, Tommy, Olagnier, David
Published in Nature communications (15.05.2024)
Published in Nature communications (15.05.2024)
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Journal Article
Author Correction: SARS-CoV2-mediated suppression of NRF2-signaling reveals potent antiviral and anti-inflammatory activity of 4-octyl-itaconate and dimethyl fumarate
Olagnier, David, Farahani, Ensieh, Thyrsted, Jacob, Blay-Cadanet, Julia, Herengt, Angela, Idorn, Manja, Hait, Alon, Hernaez, Bruno, Knudsen, Alice, Iversen, Marie Beck, Schilling, Mirjam, Jørgensen, Sofie E., Thomsen, Michelle, Reinert, Line S., Lappe, Michael, Hoang, Huy-Dung, Gilchrist, Victoria H., Hansen, Anne Louise, Ottosen, Rasmus, Nielsen, Camilla G., Møller, Charlotte, van der Horst, Demi, Peri, Suraj, Balachandran, Siddharth, Huang, Jinrong, Jakobsen, Martin, Svenningsen, Esben B., Poulsen, Thomas B., Bartsch, Lydia, Thielke, Anne L., Luo, Yonglun, Alain, Tommy, Rehwinkel, Jan, Alcamí, Antonio, Hiscott, John, Mogensen, Trine H., Paludan, Søren R., Holm, Christian K.
Published in Nature communications (21.10.2020)
Published in Nature communications (21.10.2020)
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Journal Article
The covalent reactivity of functionalized 5-hydroxy-butyrolactams is the basis for targeting of fatty acid binding protein 5 (FABP5) by the neurotrophic agent
Svenningsen, Esben B, Ottosen, Rasmus N, Jørgensen, Katrine H, Nisavic, Marija, Larsen, Camilla K, Hansen, Bente K, Wang, Yong, Lindorff-Larsen, Kresten, Tørring, Thomas, Hacker, Stephan M, Palmfeldt, Johan, Poulsen, Thomas B
Published in RSC chemical biology (05.10.2022)
Published in RSC chemical biology (05.10.2022)
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Journal Article