Phase 2, Randomized, Double-Blind Study of the Efficacy and Safety of Two Dose Regimens of Eravacycline versus Ertapenem for Adult Community-Acquired Complicated Intra-Abdominal Infections
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Published in Antimicrobial agents and chemotherapy (01.04.2014)
Published in Antimicrobial agents and chemotherapy (01.04.2014)
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Target- and Resistance-Based Mechanistic Studies with TP-434, a Novel Fluorocycline Antibiotic
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Fluorocyclines. 2. Optimization of the C-9 Side-Chain for Antibacterial Activity and Oral Efficacy
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Published in Journal of medicinal chemistry (26.01.2012)
Published in Journal of medicinal chemistry (26.01.2012)
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Assessing the Efficacy and Safety of Eravacycline vs Ertapenem in Complicated Intra-abdominal Infections in the Investigating Gram-Negative Infections Treated With Eravacycline (IGNITE 1) Trial: A Randomized Clinical Trial
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Published in JAMA surgery (01.03.2017)
Published in JAMA surgery (01.03.2017)
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Fluorocycline TP-271 Is Potent against Complicated Community-Acquired Bacterial Pneumonia Pathogens
Grossman, Trudy H, Fyfe, Corey, O'Brien, William, Hackel, Meredith, Minyard, Mary Beth, Waites, Ken B, Dubois, Jacques, Murphy, Timothy M, Slee, Andrew M, Weiss, William J, Sutcliffe, Joyce A
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Evaluation of the In Vitro Activity of Eravacycline against a Broad Spectrum of Recent Clinical Anaerobic Isolates
Snydman, David R, McDermott, Laura A, Jacobus, Nilda V, Kerstein, Kathryn, Grossman, Trudy H, Sutcliffe, Joyce A
Published in Antimicrobial agents and chemotherapy (01.05.2018)
Published in Antimicrobial agents and chemotherapy (01.05.2018)
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Eravacycline (TP-434) is efficacious in animal models of infection
Grossman, Trudy H, Murphy, Timothy M, Slee, Andrew M, Lofland, Denene, Sutcliffe, Joyce A
Published in Antimicrobial agents and chemotherapy (01.05.2015)
Published in Antimicrobial agents and chemotherapy (01.05.2015)
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Fluorocyclines. 1. 7-Fluoro-9-pyrrolidinoacetamido-6-demethyl-6-deoxytetracycline: A Potent, Broad Spectrum Antibacterial Agent
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Published in Journal of medicinal chemistry (26.01.2012)
Published in Journal of medicinal chemistry (26.01.2012)
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Heterocyclyl Tetracyclines. 1. 7‑Trifluoromethyl-8-Pyrrolidinyltetracyclines: Potent, Broad Spectrum Antibacterial Agents with Enhanced Activity against Pseudomonas aeruginosa
Deng, Yonghong, Sun, Cuixiang, Hunt, Diana K, Fyfe, Corey, Chen, Chi-Li, Grossman, Trudy H, Sutcliffe, Joyce A, Xiao, Xiao-Yi
Published in Journal of medicinal chemistry (23.03.2017)
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Clonal Relatedness of Erythromycin-Resistant Streptococcus pyogenes Isolates in Germany
Reinert, Ralf R, Lütticken, Rudolf, Sutcliffe, Joyce A, Tait-Kamradt, Amelia, Cil, Murat Y, Schorn, Holger M, Bryskier, André, Al-Lahham, Adnan
Published in Antimicrobial Agents and Chemotherapy (01.04.2004)
Published in Antimicrobial Agents and Chemotherapy (01.04.2004)
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Susceptibility of tetracyclines to Tet(a) resistance is independent of interdomain loop sequence
Fyfe, Corey, Sutcliffe, Joyce A, Grossman, Trudy H
Published in Antimicrobial agents and chemotherapy (01.05.2013)
Published in Antimicrobial agents and chemotherapy (01.05.2013)
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The Fluorocycline TP-271 Is Efficacious in Models of Aerosolized Francisella tularensis SCHU S4 Infection in BALB/c Mice and Cynomolgus Macaques
Grossman, Trudy H, Anderson, Michael S, Christ, David, Gooldy, Melanie, Henning, Lisa N, Heine, Henry S, Kindt, M Victoria, Lin, Winston, Siefkas-Patterson, Kaylyn, Radcliff, Anne K, Tam, Vincent H, Sutcliffe, Joyce A
Published in Antimicrobial agents and chemotherapy (01.08.2017)
Published in Antimicrobial agents and chemotherapy (01.08.2017)
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The Fluorocycline TP-271 Is Efficacious in Models of Aerosolized Bacillus anthracis Infection in BALB/c Mice and Cynomolgus Macaques
Grossman, Trudy H, Anderson, Michael S, Drabek, Lindsay, Gooldy, Melanie, Heine, Henry S, Henning, Lisa N, Lin, Winston, Newman, Joseph V, Nevarez, Rene, Siefkas-Patterson, Kaylyn, Radcliff, Anne K, Sutcliffe, Joyce A
Published in Antimicrobial agents and chemotherapy (01.10.2017)
Published in Antimicrobial agents and chemotherapy (01.10.2017)
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