Automated Structure- and Sequence-Based Design of Proteins for High Bacterial Expression and Stability
Goldenzweig, Adi, Goldsmith, Moshe, Hill, Shannon E., Gertman, Or, Laurino, Paola, Ashani, Yacov, Dym, Orly, Unger, Tamar, Albeck, Shira, Prilusky, Jaime, Lieberman, Raquel L., Aharoni, Amir, Silman, Israel, Sussman, Joel L., Tawfik, Dan S., Fleishman, Sarel J.
Published in Molecular cell (21.07.2016)
Published in Molecular cell (21.07.2016)
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Acetylcholinesterase: From 3D structure to function
Dvir, Hay, Silman, Israel, Harel, Michal, Rosenberry, Terrone L., Sussman, Joel L.
Published in Chemico-biological interactions (06.09.2010)
Published in Chemico-biological interactions (06.09.2010)
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Computational Studies on Acetylcholinesterases
Xu, Yechun, Cheng, Shanmei, Sussman, Joel L, Silman, Israel, Jiang, Hualiang
Published in Molecules (Basel, Switzerland) (10.08.2017)
Published in Molecules (Basel, Switzerland) (10.08.2017)
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Function and structure of inherently disordered proteins
Dunker, A Keith, Silman, Israel, Uversky, Vladimir N, Sussman, Joel L
Published in Current opinion in structural biology (01.12.2008)
Published in Current opinion in structural biology (01.12.2008)
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A fish herpesvirus highlights functional diversities among Zα domains related to phase separation induction and A-to-Z conversion
Diallo, Mamadou Amadou, Pirotte, Sébastien, Hu, Yunlong, Morvan, Léa, Rakus, Krzysztof, Suárez, Nicolás M, PoTsang, Lee, Saneyoshi, Hisao, Xu, Yan, Davison, Andrew J, Tompa, Peter, Sussman, Joel L, Vanderplasschen, Alain
Published in Nucleic acids research (25.01.2023)
Published in Nucleic acids research (25.01.2023)
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A Second Look at the Crystal Structures of Drosophila melanogaster Acetylcholinesterase in Complex with Tacrine Derivatives Provides Insights Concerning Catalytic Intermediates and the Design of Specific Insecticides
Nachon, Florian, Rosenberry, Terrone L, Silman, Israel, Sussman, Joel L
Published in Molecules (Basel, Switzerland) (06.03.2020)
Published in Molecules (Basel, Switzerland) (06.03.2020)
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Design of a stable human acid‐β‐glucosidase: towards improved Gaucher disease therapy and mutation classification
Pokorna, Sarka, Khersonsky, Olga, Lipsh‐Sokolik, Rosalie, Goldenzweig, Adi, Nielsen, Rebekka, Ashani, Yacov, Peleg, Yoav, Unger, Tamar, Albeck, Shira, Dym, Orly, Tirosh, Asa, Tarayra, Rana, Hocquemiller, Michaël, Laufer, Ralph, Ben‐Dor, Shifra, Silman, Israel, Sussman, Joel L., Fleishman, Sarel J., Futerman, Anthony H.
Published in The FEBS journal (01.07.2023)
Published in The FEBS journal (01.07.2023)
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Directed evolution of hydrolases for prevention of G-type nerve agent intoxication
Tawfik, Dan S, Gupta, Rinkoo D, Goldsmith, Moshe, Ashani, Yacov, Simo, Yair, Mullokandov, Gavriel, Bar, Hagit, Ben-David, Moshe, Leader, Haim, Margalit, Raanan, Silman, Israel, Sussman, Joel L
Published in Nature chemical biology (01.02.2011)
Published in Nature chemical biology (01.02.2011)
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Computational redesign of a mononuclear zinc metalloenzyme for organophosphate hydrolysis
Khare, Sagar D, Kipnis, Yakov, Greisen, Jr, Per, Takeuchi, Ryo, Ashani, Yacov, Goldsmith, Moshe, Song, Yifan, Gallaher, Jasmine L, Silman, Israel, Leader, Haim, Sussman, Joel L, Stoddard, Barry L, Tawfik, Dan S, Baker, David
Published in Nature chemical biology (05.02.2012)
Published in Nature chemical biology (05.02.2012)
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Flexible regions govern promiscuous binding of IL‐24 to receptors IL‐20R1 and IL‐22R1
Zahradník, Jiří, Kolářová, Lucie, Peleg, Yoav, Kolenko, Petr, Svidenská, Silvie, Charnavets, Tatsiana, Unger, Tamar, Sussman, Joel L., Schneider, Bohdan
Published in The FEBS journal (01.10.2019)
Published in The FEBS journal (01.10.2019)
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Journal Article
Torpedo californica acetylcholinesterase is stabilized by binding of a divalent metal ion to a novel and versatile 4D motif
Silman, Israel, Shnyrov, Valery L., Ashani, Yacov, Roth, Esther, Nicolas, Anne, Sussman, Joel L., Weiner, Lev
Published in Protein science (01.05.2021)
Published in Protein science (01.05.2021)
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Enzyme Evolution: An Epistatic Ratchet versus a Smooth Reversible Transition
Ben-David, Moshe, Soskine, Misha, Dubovetskyi, Artem, Cherukuri, Kesava-Phaneendra, Dym, Orly, Sussman, Joel L, Liao, Qinghua, Szeler, Klaudia, Kamerlin, Shina Caroline Lynn, Tawfik, Dan S
Published in Molecular biology and evolution (01.04.2020)
Published in Molecular biology and evolution (01.04.2020)
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