Bridging of DNA breaks activates PARP2–HPF1 to modify chromatin
Bilokapic, Silvija, Suskiewicz, Marcin J., Ahel, Ivan, Halic, Mario
Published in Nature (London) (24.09.2020)
Published in Nature (London) (24.09.2020)
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Journal Article
Serine ADP-ribosylation in DNA-damage response regulation
Palazzo, Luca, Suskiewicz, Marcin J, Ahel, Ivan
Published in Current opinion in genetics & development (01.12.2021)
Published in Current opinion in genetics & development (01.12.2021)
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Journal Article
Arginine phosphorylation marks proteins for degradation by a Clp protease
Trentini, Débora Broch, Suskiewicz, Marcin Józef, Heuck, Alexander, Kurzbauer, Robert, Deszcz, Luiza, Mechtler, Karl, Clausen, Tim
Published in Nature (London) (03.11.2016)
Published in Nature (London) (03.11.2016)
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Journal Article
Progress and outlook in studying the substrate specificities of PARPs and related enzymes
Suskiewicz, Marcin J., Palazzo, Luca, Hughes, Rebecca, Ahel, Ivan
Published in The FEBS journal (01.04.2021)
Published in The FEBS journal (01.04.2021)
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Journal Article
Structural insights into the regulation of the human E2∼SUMO conjugate through analysis of its stable mimetic
Goffinont, Stéphane, Coste, Franck, Prieu-Serandon, Pierre, Mance, Lucija, Gaudon, Virginie, Garnier, Norbert, Castaing, Bertrand, Suskiewicz, Marcin Józef
Published in The Journal of biological chemistry (01.07.2023)
Published in The Journal of biological chemistry (01.07.2023)
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Journal Article
ADP-ribosylation from molecular mechanisms to therapeutic implications
Suskiewicz, Marcin J., Prokhorova, Evgeniia, Rack, Johannes G.M., Ahel, Ivan
Published in Cell (12.10.2023)
Published in Cell (12.10.2023)
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Journal Article
HPF1 completes the PARP active site for DNA damage-induced ADP-ribosylation
Suskiewicz, Marcin J., Zobel, Florian, Ogden, Tom E. H., Fontana, Pietro, Ariza, Antonio, Yang, Ji-Chun, Zhu, Kang, Bracken, Lily, Hawthorne, William J., Ahel, Dragana, Neuhaus, David, Ahel, Ivan
Published in Nature (London) (01.03.2020)
Published in Nature (London) (01.03.2020)
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Journal Article
Serine-linked PARP1 auto-modification controls PARP inhibitor response
Prokhorova, Evgeniia, Zobel, Florian, Smith, Rebecca, Zentout, Siham, Gibbs-Seymour, Ian, Schützenhofer, Kira, Peters, Alessandra, Groslambert, Joséphine, Zorzini, Valentina, Agnew, Thomas, Brognard, John, Nielsen, Michael L., Ahel, Dragana, Huet, Sébastien, Suskiewicz, Marcin J., Ahel, Ivan
Published in Nature communications (01.07.2021)
Published in Nature communications (01.07.2021)
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Journal Article
Unrestrained poly-ADP-ribosylation provides insights into chromatin regulation and human disease
Prokhorova, Evgeniia, Agnew, Thomas, Wondisford, Anne R., Tellier, Michael, Kaminski, Nicole, Beijer, Danique, Holder, James, Groslambert, Josephine, Suskiewicz, Marcin J., Zhu, Kang, Reber, Julia M., Krassnig, Sarah C., Palazzo, Luca, Murphy, Shona, Nielsen, Michael L., Mangerich, Aswin, Ahel, Dragana, Baets, Jonathan, O’Sullivan, Roderick J., Ahel, Ivan
Published in Molecular cell (17.06.2021)
Published in Molecular cell (17.06.2021)
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Journal Article
Serine ADP-ribosylation in Drosophila provides insights into the evolution of reversible ADP-ribosylation signalling
Fontana, Pietro, Buch-Larsen, Sara C., Suyari, Osamu, Smith, Rebecca, Suskiewicz, Marcin J., Schützenhofer, Kira, Ariza, Antonio, Rack, Johannes Gregor Matthias, Nielsen, Michael L., Ahel, Ivan
Published in Nature communications (02.06.2023)
Published in Nature communications (02.06.2023)
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Journal Article
Ubiquitylation of nucleic acids by DELTEX ubiquitin E3 ligase DTX3L
Zhu, Kang, Chatrin, Chatrin, Suskiewicz, Marcin J, Aucagne, Vincent, Foster, Benjamin, Kessler, Benedikt M, Gibbs-Seymour, Ian, Ahel, Dragana, Ahel, Ivan
Published in EMBO reports (10.10.2024)
Published in EMBO reports (10.10.2024)
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Journal Article
DELTEX E3 ligases ubiquitylate ADP-ribosyl modification on protein substrates
Zhu, Kang, Suskiewicz, Marcin J, Hloušek-Kasun, Andrea, Meudal, Hervé, Mikoč, Andreja, Aucagne, Vincent, Ahel, Dragana, Ahel, Ivan
Published in Science advances (07.10.2022)
Published in Science advances (07.10.2022)
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Journal Article
DELTEX E3 ligases ubiquitylate ADP-ribosyl modification on nucleic acids
Zhu, Kang, Suskiewicz, Marcin J, Chatrin, Chatrin, Strømland, Øyvind, Dorsey, Bryan W, Aucagne, Vincent, Ahel, Dragana, Ahel, Ivan
Published in Nucleic acids research (25.01.2024)
Published in Nucleic acids research (25.01.2024)
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Journal Article
Structural basis for the disaggregase activity and regulation of Hsp104
Heuck, Alexander, Schitter-Sollner, Sonja, Suskiewicz, Marcin Józef, Kurzbauer, Robert, Kley, Juliane, Schleiffer, Alexander, Rombaut, Pascaline, Herzog, Franz, Clausen, Tim
Published in eLife (30.11.2016)
Published in eLife (30.11.2016)
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Journal Article
Updated protein domain annotation of the PARP protein family sheds new light on biological function
Suskiewicz, Marcin J, Munnur, Deeksha, Strømland, Øyvind, Yang, Ji-Chun, Easton, Laura E, Chatrin, Chatrin, Zhu, Kang, Baretić, Domagoj, Goffinont, Stéphane, Schuller, Marion, Wu, Wing-Fung, Elkins, Jonathan M, Ahel, Dragana, Sanyal, Sumana, Neuhaus, David, Ahel, Ivan
Published in Nucleic acids research (25.08.2023)
Published in Nucleic acids research (25.08.2023)
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Journal Article
An Atypical Mechanism of SUMOylation of Neurofibromin SecPH Domain Provides New Insights into SUMOylation Site Selection
Bergoug, Mohammed, Mosrin, Christine, Serrano, Amandine, Godin, Fabienne, Doudeau, Michel, Dundović, Iva, Goffinont, Stephane, Normand, Thierry, Suskiewicz, Marcin J., Vallée, Béatrice, Bénédetti, Hélène
Published in Journal of molecular biology (15.11.2024)
Published in Journal of molecular biology (15.11.2024)
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Journal Article
The potential of PARP inhibitors in targeted cancer therapy and immunotherapy
Hunia, Jaromir, Gawalski, Karol, Szredzka, Aleksandra, Suskiewicz, Marcin J, Nowis, Dominika
Published in Frontiers in molecular biosciences (01.12.2022)
Published in Frontiers in molecular biosciences (01.12.2022)
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Journal Article
Structural and functional determinants of the archaeal 8-oxoguanine-DNA glycosylase AGOG for DNA damage recognition and processing
Franck, Coste, Stéphane, Goffinont, Julien, Cros, Virginie, Gaudon, Martine, Guérin, Norbert, Garnier, Fabrice, Confalonieri, Didier, Flament, Josef, Suskiewicz Marcin, Bertrand, Castaing
Published in Nucleic acids research (28.10.2022)
Published in Nucleic acids research (28.10.2022)
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Journal Article