Induced and pre-existing anti-polyethylene glycol antibody in a trial of every 3-week dosing of pegloticase for refractory gout, including in organ transplant recipients
Hershfield, Michael S, Ganson, Nancy J, Kelly, Susan J, Scarlett, Edna L, Jaggers, Denise A, Sundy, John S
Published in Arthritis research & therapy (07.03.2014)
Published in Arthritis research & therapy (07.03.2014)
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Extending the Clinical Phenotype of Adenosine Deaminase 2 Deficiency
Ben-Ami, Tal, MD, Revel-Vilk, Shoshana, MD, MSc, Brooks, Rebecca, MD, Shaag, Avraham, PhD, Hershfield, Michael S., MD, Kelly, Susan J., PhD, Ganson, Nancy J., PhD, Kfir-Erenfeld, Shlomit, PhD, Weintraub, Michael, MD, Elpeleg, Orly, MD, Berkun, Yackov, MD, Stepensky, Polina, MD
Published in The Journal of pediatrics (01.10.2016)
Published in The Journal of pediatrics (01.10.2016)
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Uric acid is a danger signal of increasing risk for osteoarthritis through inflammasome activation
Denoble, Anna E, Huffman, Kim M, Stabler, Thomas V, Kelly, Susan J, Hershfield, Michael S, McDaniel, Gary E, Coleman, R. Edward, Kraus, Virginia B
Published in Proceedings of the National Academy of Sciences - PNAS (01.02.2011)
Published in Proceedings of the National Academy of Sciences - PNAS (01.02.2011)
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Hematopoietic stem cell transplantation rescues the immunologic phenotype and prevents vasculopathy in patients with adenosine deaminase 2 deficiency
Van Eyck, Lien, MD, Hershfield, Michael S., MD, Pombal, Diana, MSc, Kelly, Susan J., PhD, Ganson, Nancy J., PhD, Moens, Leen, PhD, Frans, Glynis, MPharm, Schaballie, Heidi, MD, De Hertogh, Gert, MD, PhD, Dooley, James, MSc, Bossuyt, Xavier, MD, PhD, Wouters, Carine, MD, PhD, Liston, Adrian, PhD, Meyts, Isabelle, MD, PhD
Published in Journal of allergy and clinical immunology (01.01.2015)
Published in Journal of allergy and clinical immunology (01.01.2015)
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Journal Article
Treating gout with pegloticase, a PEGylated urate oxidase, provides insight into the importance of uric acid as an antioxidant in vivo
Hershfield, Michael S., Roberts, L. Jackson, Ganson, Nancy J., Kelly, Susan J., Santisteban, Ines, Scarlett, Edna, Jaggers, Denise, Sundy, John S., Fridovich, Irwin
Published in Proceedings of the National Academy of Sciences - PNAS (10.08.2010)
Published in Proceedings of the National Academy of Sciences - PNAS (10.08.2010)
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Journal Article
Adenosine deaminase type 2 deficiency masquerading as GATA2 deficiency: Successful hematopoietic stem cell transplantation
Hsu, Amy P., BA, West, Robert R., PhD, Calvo, Katherine R., MD, PhD, Cuellar-Rodriguez, Jennifer, MD, Parta, Mark, MD, Kelly, Susan J., PhD, Ganson, Nancy J., PhD, Hershfield, Michael S., MD, Holland, Steven M., MD, Hickstein, Dennis D., MD
Published in Journal of allergy and clinical immunology (01.08.2016)
Published in Journal of allergy and clinical immunology (01.08.2016)
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Journal Article
Sequence‐Based Screening of Patients With Idiopathic Polyarteritis Nodosa, Granulomatosis With Polyangiitis, and Microscopic Polyangiitis for Deleterious Genetic Variants in ADA2
Schnappauf, Oskar, Sampaio Moura, Natalia, Aksentijevich, Ivona, Stoffels, Monique, Ombrello, Amanda K., Hoffmann, Patrycja, Barron, Karyl, Remmers, Elaine F., Hershfield, Michael, Kelly, Susan J., Cuthbertson, David, Carette, Simon, Chung, Sharon A., Forbess, Lindsy, Khalidi, Nader A., Koening, Curry L., Langford, Carol A., McAlear, Carol A., Monach, Paul A., Moreland, Larry, Pagnoux, Christian, Seo, Philip, Springer, Jason M., Sreih, Antoine G., Warrington, Kenneth J., Ytterberg, Steven R., Kastner, Daniel L., Grayson, Peter C., Merkel, Peter A.
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.03.2021)
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.03.2021)
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Journal Article
Control of hyperuricemia in subjects with refractory gout, and induction of antibody against poly(ethylene glycol) (PEG), in a phase I trial of subcutaneous PEGylated urate oxidase
Ganson, Nancy J, Kelly, Susan J, Scarlett, Edna, Sundy, John S, Hershfield, Michael S
Published in Arthritis research & therapy (01.01.2006)
Published in Arthritis research & therapy (01.01.2006)
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Journal Article
Diabetes insipidus in uricase-deficient mice: A model for evaluating therapy with poly(ethylene glycol)-modified uricase
KELLY, Susan J, DELNOMDEDIEU, Marielle, OLIVERIO, Michael I, WILLIAMS, L. David, SAIFER, Mark G. P, SHERMAN, Merry R, COFFMAN, Thomas M, JOHNSON, G. Allan, HERSHFIELD, Michael S
Published in Journal of the American Society of Nephrology (01.05.2001)
Published in Journal of the American Society of Nephrology (01.05.2001)
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Early-Onset Stroke and Vasculopathy Associated with Mutations in ADA2
Zhou, Qing, Yang, Dan, Ombrello, Amanda K, Zavialov, Andrey V, Toro, Camilo, Zavialov, Anton V, Stone, Deborah L, Chae, Jae Jin, Rosenzweig, Sergio D, Bishop, Kevin, Barron, Karyl S, Kuehn, Hye Sun, Hoffmann, Patrycja, Negro, Alejandra, Tsai, Wanxia L, Cowen, Edward W, Pei, Wuhong, Milner, Joshua D, Silvin, Christopher, Heller, Theo, Chin, David T, Patronas, Nicholas J, Barber, John S, Lee, Chyi-Chia R, Wood, Geryl M, Ling, Alexander, Kelly, Susan J, Kleiner, David E, Mullikin, James C, Ganson, Nancy J, Kong, Heidi H, Hambleton, Sophie, Candotti, Fabio, Quezado, Martha M, Calvo, Katherine R, Alao, Hawwa, Barham, Beverly K, Jones, Anne, Meschia, James F, Worrall, Bradford B, Kasner, Scott E, Rich, Stephen S, Goldbach-Mansky, Raphaela, Abinun, Mario, Chalom, Elizabeth, Gotte, Alisa C, Punaro, Marilynn, Pascual, Virginia, Verbsky, James W, Torgerson, Troy R, Singer, Nora G, Gershon, Timothy R, Ozen, Seza, Karadag, Omer, Fleisher, Thomas A, Remmers, Elaine F, Burgess, Shawn M, Moir, Susan L, Gadina, Massimo, Sood, Raman, Hershfield, Michael S, Boehm, Manfred, Kastner, Daniel L, Aksentijevich, Ivona
Published in The New England journal of medicine (06.03.2014)
Published in The New England journal of medicine (06.03.2014)
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Journal Article
Pharmacokinetics and pharmacodynamics of intravenous PEGylated recombinant mammalian urate oxidase in patients with refractory gout
Sundy, John S., Ganson, Nancy J., Kelly, Susan J., Scarlett, Edna L., Rehrig, Claudia D., Huang, William, Hershfield, Michael S.
Published in Arthritis and rheumatism (01.03.2007)
Published in Arthritis and rheumatism (01.03.2007)
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Journal Article
Elucidating the pathogenesis of adenosine deaminase 2 deficiency: current status and unmet needs
Tarrant, Teresa K, Kelly, Susan J., Hershfield, Michael S
Published in Expert opinion on orphan drugs (02.12.2021)
Published in Expert opinion on orphan drugs (02.12.2021)
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Case 8—2000 Intraoperative bispectral index monitoring and early extubation after cardiac surgery in patients with a history of awareness under anesthesia
Kelly, Susan J., Myles, Paul S., Bain, David, Rosow, Carl, Ramsay, James
Published in Journal of cardiothoracic and vascular anesthesia (01.12.2000)
Published in Journal of cardiothoracic and vascular anesthesia (01.12.2000)
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