Prediction of the in vivo OATP1B1-mediated drug–drug interaction potential of an investigational drug against a range of statins
Sharma, Pradeep, Butters, Caroline J., Smith, Veronica, Elsby, Robert, Surry, Dominic
Published in European journal of pharmaceutical sciences (30.08.2012)
Published in European journal of pharmaceutical sciences (30.08.2012)
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Journal Article
The Utility of In Vitro Data in Making Accurate Predictions of Human P-Glycoprotein-Mediated Drug-Drug Interactions: A Case Study for AZD5672
ELSBY, Robert, GILLEN, Michael, BUTTERS, Caroline, IMISSON, Gemma, SHARMA, Pradeep, SMITH, Veronica, SURRY, Dominic D
Published in Drug metabolism and disposition (01.02.2011)
Published in Drug metabolism and disposition (01.02.2011)
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Journal Article
Validation of membrane vesicle-based breast cancer resistance protein and multidrug resistance protein 2 assays to assess drug transport and the potential for drug-drug interaction to support regulatory submissions
Elsby, Robert, Smith, Veronica, Fox, Lisa, Stresser, David, Butters, Caroline, Sharma, Pradeep, Surry, Dominic D.
Published in Xenobiotica (01.09.2011)
Published in Xenobiotica (01.09.2011)
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Journal Article
Effects of Fostamatinib on the Pharmacokinetics of the CYP2C8 Substrate Pioglitazone: Results From In Vitro and Phase 1 Clinical Studies
Martin, Paul, Gillen, Michael, Millson, David, Oliver, Stuart, Brealey, Clive, Surry, Dominic, Sweeny, David, Lau, David, Leese, Philip
Published in Clinical pharmacology in drug development (01.05.2016)
Published in Clinical pharmacology in drug development (01.05.2016)
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Journal Article
Gene expression profiling of drug metabolism and toxicology markers using a low-density DNA microarray
de Longueville, Françoise, Surry, Dominic, Meneses-Lorente, Georgina, Bertholet, Vincent, Talbot, Valérie, Evrard, Stephanie, Chandelier, Nathalie, Pike, Andrew, Worboys, Phil, Rasson, Jean-Paul, Le Bourdellès, Béatrice, Remacle, José
Published in Biochemical pharmacology (01.07.2002)
Published in Biochemical pharmacology (01.07.2002)
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Journal Article
Solitary Inhibition of the Breast Cancer Resistance Protein Efflux Transporter Results in a Clinically Significant Drug-Drug Interaction with Rosuvastatin by Causing up to a 2-Fold Increase in Statin Exposure
Elsby, Robert, Martin, Paul, Surry, Dominic, Sharma, Pradeep, Fenner, Katherine
Published in Drug metabolism and disposition (01.03.2016)
Published in Drug metabolism and disposition (01.03.2016)
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Journal Article
Comparison of the effects of some CYP3A and other enzyme inducers on replicative DNA synthesis and cytochrome P450 isoforms in rat liver
Lake, Brian G., Renwick, Anthony B., Cunninghame, Morag E., Price, Roger J., Surry, Dominic, Evans, David C.
Published in Toxicology (Amsterdam) (02.11.1998)
Published in Toxicology (Amsterdam) (02.11.1998)
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Journal Article
The use of bioreactors as in vitro models in pharmaceutical research
Ginai, Maaria, Elsby, Robert, Hewitt, Christopher J., Surry, Dominic, Fenner, Katherine, Coopman, Karen
Published in Drug discovery today (01.10.2013)
Published in Drug discovery today (01.10.2013)
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Journal Article
Quantification of proteins by flow cytometry: Quantification of human hepatic transporter P-gp and OATP1B1 using flow cytometry and mass spectrometry
Hogg, Karen, Thomas, Jerry, Ashford, David, Cartwright, Jared, Coldwell, Ruth, Weston, Daniel J., Pillmoor, John, Surry, Dominic, O’Toole, Peter
Published in Methods (San Diego, Calif.) (01.07.2015)
Published in Methods (San Diego, Calif.) (01.07.2015)
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Journal Article
In vitro risk assessment of AZD9056 perpetrating a transporter-mediated drug–drug interaction with methotrexate
Elsby, Robert, Fox, Lisa, Stresser, David, Layton, Mark, Butters, Caroline, Sharma, Pradeep, Smith, Veronica, Surry, Dominic
Published in European journal of pharmaceutical sciences (18.05.2011)
Published in European journal of pharmaceutical sciences (18.05.2011)
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Journal Article
Antagonists of the Human A2A Adenosine Receptor. 4. Design, Synthesis, and Preclinical Evaluation of 7-Aryltriazolo[4,5-d]pyrimidines
Gillespie, Roger J, Bamford, Samantha J, Botting, Ruth, Comer, Mike, Denny, Sarah, Gaur, Suneel, Griffin, Michael, Jordan, Allan M, Knight, Anthony R, Lerpiniere, Joanne, Leonardi, Stefania, Lightowler, Sean, McAteer, Steven, Merrett, Angela, Misra, Anil, Padfield, Antony, Reece, Mark, Saadi, Mona, Selwood, Daniel L, Stratton, Gemma C, Surry, Dominic, Todd, Richard, Tong, Xin, Ruston, Vicki, Upton, Rebecca, Weiss, Scott M
Published in Journal of medicinal chemistry (08.01.2009)
Published in Journal of medicinal chemistry (08.01.2009)
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Journal Article
Antagonists of the Human A(2A) Adenosine Receptor. 4. Design, Synthesis, and Preclinical Evaluation of 7-Aryltriazolo[4,5-d]pyrimidines
Gillespie, Roger J., Bamford, Samantha J., Botting, Ruth, Comer, Mike, Denny, Sarah, Gaur, Suneel, Griffin, Michael, Jordan, Allan M., Knight, Anthony R., Lerpiniere, Joanne, Leonardi, Stefania, Lightowler, Sean, McAteer, Steven, Merrett, Angela, Misra, Anil, Padfield, Antony, Reece, Mark, Saadi, Mona, Selwood, Daniel L., Stratton, Gemma C., Surry, Dominic, Todd, Richard, Tong, Xin, Ruston, Vicki, Upton, Rebecca, Weiss, Scott M.
Published in Journal of medicinal chemistry (08.01.2009)
Published in Journal of medicinal chemistry (08.01.2009)
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Journal Article
Antagonists of the Human A 2A Adenosine Receptor. 4. Design, Synthesis, and Preclinical Evaluation of 7-Aryltriazolo[4,5- d ]pyrimidines
Gillespie, Roger J., Bamford, Samantha J., Botting, Ruth, Comer, Mike, Denny, Sarah, Gaur, Suneel, Griffin, Michael, Jordan, Allan M., Knight, Anthony R., Lerpiniere, Joanne, Leonardi, Stefania, Lightowler, Sean, McAteer, Steven, Merrett, Angela, Misra, Anil, Padfield, Antony, Reece, Mark, Saadi, Mona, Selwood, Daniel L., Stratton, Gemma C., Surry, Dominic, Todd, Richard, Tong, Xin, Ruston, Vicki, Upton, Rebecca, Weiss, Scott M.
Published in Journal of medicinal chemistry (08.01.2009)
Published in Journal of medicinal chemistry (08.01.2009)
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Journal Article