An ensemble machine learning model generates a focused screening library for the identification of CDK8 inhibitors
Lin, Tony Eight, Yen, Dyan, HuangFu, Wei‐Chun, Wu, Yi‐Wen, Hsu, Jui‐Yi, Yen, Shih‐Chung, Sung, Tzu‐Ying, Hsieh, Jui‐Hua, Pan, Shiow‐Lin, Yang, Chia‐Ron, Huang, Wei‐Jan, Hsu, Kai‐Cheng
Published in Protein science (01.06.2024)
Published in Protein science (01.06.2024)
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Journal Article
Establishment of extensive artificial intelligence models for kinase inhibitor prediction: Identification of novel PDGFRB inhibitors
Lien, Ssu-Ting, Lin, Tony Eight, Hsieh, Jui-Hua, Sung, Tzu-Ying, Chen, Jun-Hong, Hsu, Kai-Cheng
Published in Computers in biology and medicine (01.04.2023)
Published in Computers in biology and medicine (01.04.2023)
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Journal Article
Novel Class IIa-Selective Histone Deacetylase Inhibitors Discovered Using an in Silico Virtual Screening Approach
Hsu, Kai-Cheng, Liu, Chang-Yi, Lin, Tony Eight, Hsieh, Jui-Hua, Sung, Tzu-Ying, Tseng, Hui-Ju, Yang, Jinn-Moon, Huang, Wei-Jan
Published in Scientific reports (12.06.2017)
Published in Scientific reports (12.06.2017)
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Journal Article
Design, synthesis, and biological evaluation of indolin-2-one derivatives as novel cyclin-dependent protein kinase 8 (CDK8) inhibitors
Hsu, Jui-Yi, Hsu, Kai-Cheng, Sun, Ching, Chou, Ching-Hsuan, Lin, Tony Eight, Sung, Tzu-Ying, Tseng, Hui-Ju, Yen, Shih-Chung, Yang, Chia-Ron, Huang, Wei-Jan
Published in Biomedicine & pharmacotherapy (01.03.2023)
Published in Biomedicine & pharmacotherapy (01.03.2023)
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Journal Article
Discovery of a novel cyclin-dependent kinase 8 inhibitor with an oxindole core for anti-inflammatory treatment
Lin, Tony Eight, Yang, Chia-Ron, Chou, Ching-Hsuan, Hsu, Jui-Yi, Chao, Min-Wu, Sung, Tzu-Ying, Hsieh, Jui-Hua, Huang, Wei-Jan, Hsu, Kai-Cheng
Published in Biomedicine & pharmacotherapy (01.02.2022)
Published in Biomedicine & pharmacotherapy (01.02.2022)
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Journal Article
ACR11 modulates levels of reactive oxygen species and salicylic acid-associated defense response in Arabidopsis
Singh, Shashi Kant, Sung, Tzu-Ying, Chung, Tsui-Yun, Lin, Shao-Yu, Lin, Sang-Chu, Liao, Jo-Chien, Hsieh, Wei-Yu, Hsieh, Ming-Hsiun
Published in Scientific reports (07.08.2018)
Published in Scientific reports (07.08.2018)
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Journal Article
Identification and analysis of a selective DYRK1A inhibitor
Lin, Tony Eight, Chao, Min-Wu, HuangFu, Wei-Chun, Tu, Huang-Ju, Peng, Zhao-Xiang, Su, Chih-Jou, Sung, Tzu-Ying, Hsieh, Jui-Hua, Lee, Cheng-Chung, Yang, Chia-Ron, Pan, Shiow-Lin, Hsu, Kai-Cheng
Published in Biomedicine & pharmacotherapy (01.02.2022)
Published in Biomedicine & pharmacotherapy (01.02.2022)
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Journal Article
Structure-based virtual screening and biological evaluation of novel small-molecule BTK inhibitors
Lin, Tony Eight, Sung, Li-Chin, Chao, Min-Wu, Li, Min, Zheng, Jia-Huei, Sung, Tzu-Ying, Hsieh, Jui-Hua, Yang, Chia-Ron, Lee, Hsueh-Yun, Cho, Er-Chieh, Hsu, Kai-Cheng
Published in Journal of enzyme inhibition and medicinal chemistry (01.12.2022)
Published in Journal of enzyme inhibition and medicinal chemistry (01.12.2022)
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Journal Article
In silico identification and biological evaluation of a selective MAP4K4 inhibitor against pancreatic cancer
Chang, Chao-Di, Chao, Min-Wu, Lee, Hsueh-Yun, Liu, Yi-Ting, Tu, Huang-Ju, Lien, Ssu-Ting, Lin, Tony Eight, Sung, Tzu-Ying, Yen, Shih-Chung, Huang, Sing-Han, Hsu, Kai-Cheng, Pan, Shiow-Lin
Published in Journal of enzyme inhibition and medicinal chemistry (01.12.2023)
Published in Journal of enzyme inhibition and medicinal chemistry (01.12.2023)
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Journal Article
A site-moiety map and virtual screening approach for discovery of novel 5-LOX inhibitors
Hsu, Kai-Cheng, HuangFu, Wei-Chun, Lin, Tony Eight, Chao, Min-Wu, Sung, Tzu-Ying, Chen, Yi-Ying, Pan, Shiow-Lin, Lee, Jih-Chin, Tzou, Shey-Cherng, Sun, Chung-Ming, Yang, Jinn-Moon
Published in Scientific reports (29.06.2020)
Published in Scientific reports (29.06.2020)
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Journal Article
Identification of a dual TAOK1 and MAP4K5 inhibitor using a structure-based virtual screening approach
Chao, Min-Wu, Lin, Tony Eight, HuangFu, Wei-Chun, Chang, Chao-Di, Tu, Huang-Ju, Chen, Liang-Chieh, Yen, Shih-Chung, Sung, Tzu-Ying, Huang, Wei-Jan, Yang, Chia-Ron, Pan, Shiow-Lin, Hsu, Kai-Cheng
Published in Journal of enzyme inhibition and medicinal chemistry (01.01.2021)
Published in Journal of enzyme inhibition and medicinal chemistry (01.01.2021)
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Journal Article
A Novel Selective JAK2 Inhibitor Identified Using Pharmacological Interactions
Lin, Tony Eight, HuangFu, Wei-Chun, Chao, Min-Wu, Sung, Tzu-Ying, Chang, Chao-Di, Chen, Yi-Ying, Hsieh, Jui-Hua, Tu, Huang-Ju, Huang, Han-Li, Pan, Shiow-Lin, Hsu, Kai-Cheng
Published in Frontiers in pharmacology (04.12.2018)
Published in Frontiers in pharmacology (04.12.2018)
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Journal Article
Identification of neuraminidase inhibitors against dual H274Y/I222R mutant strains
Hsu, Kai-Cheng, Hung, Hui-Chen, HuangFu, Wei-Chun, Sung, Tzu-Ying, Eight Lin, Tony, Fang, Ming-Yu, Chen, I-Jung, Pathak, Nikhil, Hsu, John T.-A., Yang, Jinn-Moon
Published in Scientific reports (26.09.2017)
Published in Scientific reports (26.09.2017)
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Journal Article
Supercritical fluid extracts of rosemary [Rosemarinus officinalis] leaves exhibit potent anti-inflammation and anti-tumor effects
Peng, C.H.(Hungkuang Univ., Taichung (Taiwan)), Su, J.D, Chyau, C.C, Sung, T.Y, Ho, S.S, Peng, C.C, Peng, R.Y
Published in Bioscience, biotechnology, and biochemistry (01.09.2007)
Published in Bioscience, biotechnology, and biochemistry (01.09.2007)
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Journal Article
Anchor-based classification and type-C inhibitors for tyrosine kinases
Hsu, Kai-Cheng, Sung, Tzu-Ying, Lin, Chih-Ta, Chiu, Yi-Yuan, Hsu, John T.-A., Hung, Hui-Chen, Sun, Chung-Ming, Barve, Indrajeet, Chen, Wen-Liang, Huang, Wen-Chien, Huang, Chin-Ting, Chen, Chun-Hwa, Yang, Jinn-Moon
Published in Scientific reports (16.06.2015)
Published in Scientific reports (16.06.2015)
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Journal Article
Identification of selective dual-specificity tyrosine phosphorylation-regulated kinase 1A (DYRK1A) inhibitors and their effects on tau and microtubule
Wu, Yi-Wen, HuangFu, Wei-Chun, Lin, Tony Eight, Peng, Chao-Hsiang, Tu, Huang-Ju, Sung, Ting-Yi, Sung, Tzu-Ying, Yen, Shih-Chung, Pan, Shiow-Lin, Hsu, Kai-Cheng
Published in International journal of biological macromolecules (01.02.2024)
Published in International journal of biological macromolecules (01.02.2024)
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