Discovery of a Novel Shp2 Protein Tyrosine Phosphatase Inhibitor
Chen, Liwei, Sung, Shen-Shu, Yip, M L Richard, Lawrence, Harshani R, Ren, Yuan, Guida, Wayne C, Sebti, Said M, Lawrence, Nicholas J, Wu, Jie
Published in Molecular pharmacology (01.08.2006)
Published in Molecular pharmacology (01.08.2006)
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Journal Article
A novel dual inhibitor of microtubule and Bruton’s Tyrosine Kinase inhibits survival of multiple myeloma and osteoclastogenesis
Pandey, Manoj K, Gowda, Krishne, Sung, Shen-shu, Abraham, Thomas, Budak-Alpdogan, Tulin, Talamo, Giampolo, Dovat, Sinisa, Amin, Shantu
Published in Experimental hematology (01.09.2017)
Published in Experimental hematology (01.09.2017)
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Journal Article
Gambogic acid inhibits multiple myeloma mediated osteoclastogenesis through suppression of chemokine receptor CXCR4 signaling pathways
Pandey, Manoj K, Kale, Vijay P, Song, Chunhua, Sung, Shen-shu, Sharma, Arun K, Talamo, Giampaolo, Dovat, Sinisa, Amin, Shantu G
Published in Experimental hematology (01.10.2014)
Published in Experimental hematology (01.10.2014)
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Journal Article
Characterization of a novel anti-cancer compound for astrocytomas
Lee, Sang Y, Slagle-Webb, Becky, Rizk, Elias, Patel, Akshal, Miller, Patti A, Sung, Shen-Shu, Connor, James R
Published in PloS one (25.09.2014)
Published in PloS one (25.09.2014)
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Journal Article
A small-molecule E2F inhibitor blocks growth in a melanoma culture model
Ma, Yihong, Kurtyka, Courtney A, Boyapalle, Sandhya, Sung, Shen-Shu, Lawrence, Harshani, Guida, Wayne, Cress, W Douglas
Published in Cancer research (Chicago, Ill.) (01.08.2008)
Published in Cancer research (Chicago, Ill.) (01.08.2008)
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Journal Article
A novel selective multikinase inhibitor of ROCK and MRCK effectively blocks cancer cell migration and invasion
Kale, Vijay Pralhad, Hengst, Jeremy A, Desai, Dhimant H, Dick, Taryn E, Choe, Katherine N, Colledge, Ashley L, Takahashi, Yoshinori, Sung, Shen-Shu, Amin, Shantu G, Yun, Jong K
Published in Cancer letters (28.11.2014)
Published in Cancer letters (28.11.2014)
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Journal Article
Fragment-Based and Structure-Guided Discovery and Optimization of Rho Kinase Inhibitors
Li, Rongshi, Martin, Mathew P, Liu, Yan, Wang, Binglin, Patel, Ronil A, Zhu, Jin-Yi, Sun, Nan, Pireddu, Roberta, Lawrence, Nicholas J, Li, Jiannong, Haura, Eric B, Sung, Shen-Shu, Guida, Wayne C, Schonbrunn, Ernst, Sebti, Said M
Published in Journal of medicinal chemistry (08.03.2012)
Published in Journal of medicinal chemistry (08.03.2012)
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Journal Article
Inhibitors of Src Homology-2 Domain Containing Protein Tyrosine Phosphatase-2 (Shp2) Based on Oxindole Scaffolds
Lawrence, Harshani R, Pireddu, Roberta, Chen, Liwei, Luo, Yunting, Sung, Shen-Shu, Szymanski, Ann Marie, Yip, M. L. Richard, Guida, Wayne C, Sebti, Saïd M, Wu, Jie, Lawrence, Nicholas J
Published in Journal of medicinal chemistry (28.08.2008)
Published in Journal of medicinal chemistry (28.08.2008)
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Journal Article
Inhibition of cellular Shp2 activity by a methyl ester analog of SPI-112
Chen, Liwei, Pernazza, Daniele, Scott, Latanya M., Lawrence, Harshani R., Ren, Yuan, Luo, Yunting, Wu, Xin, Sung, Shen-Shu, Guida, Wayne C., Sebti, Said M., Lawrence, Nicholas J., Wu, Jie
Published in Biochemical pharmacology (15.09.2010)
Published in Biochemical pharmacology (15.09.2010)
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Journal Article
Targeting sphingosine-1-phosphate receptors in cancer
Watters, Rebecca J, Wang, Hong-Gang, Sung, Shen-Shu, Loughran, Thomas P, Liu, Xin
Published in Anti-cancer agents in medicinal chemistry (01.11.2011)
Published in Anti-cancer agents in medicinal chemistry (01.11.2011)
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Journal Article
Pyridylthiazole-based ureas as inhibitors of Rho associated protein kinases (ROCK1 and 2)
Pireddu, Roberta, Forinash, Kara D, Sun, Nan N, Martin, Mathew P, Sung, Shen-Shu, Alexander, Brian, Zhu, Jin-Yi, Guida, Wayne C, Schönbrunn, Ernst, Sebti, Saïd M, Lawrence, Nicholas J
Published in MedChemComm (01.06.2012)
Published in MedChemComm (01.06.2012)
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Journal Article
Discovery of Marinopyrrole A (Maritoclax) as a Selective Mcl-1 Antagonist that Overcomes ABT-737 Resistance by Binding to and Targeting Mcl-1 for Proteasomal Degradation
Doi, Kenichiro, Li, Rongshi, Sung, Shen-Shu, Wu, Hongwei, Liu, Yan, Manieri, Wanda, Krishnegowda, Gowdahalli, Awwad, Andy, Dewey, Alden, Liu, Xin, Amin, Shantu, Cheng, Chunwei, Qin, Yong, Schonbrunn, Ernst, Daughdrill, Gary, Loughran, Thomas P., Sebti, Said, Wang, Hong-Gang
Published in The Journal of biological chemistry (23.03.2012)
Published in The Journal of biological chemistry (23.03.2012)
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Journal Article
The BH3 α-Helical Mimic BH3-M6 Disrupts Bcl-XL, Bcl-2, and MCL-1 Protein-Protein Interactions with Bax, Bak, Bad, or Bim and Induces Apoptosis in a Bax- and Bim-dependent Manner
Kazi, Aslamuzzaman, Sun, Jiazhi, Doi, Kenichiro, Sung, Shen-Shu, Takahashi, Yoshinori, Yin, Hang, Rodriguez, Johanna M., Becerril, Jorge, Berndt, Norbert, Hamilton, Andrew D., Wang, Hong-Gang, Sebti, Saïd M.
Published in The Journal of biological chemistry (18.03.2011)
Published in The Journal of biological chemistry (18.03.2011)
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Journal Article
The apoptotic mechanism of action of the sphingosine kinase 1 selective inhibitor SKI-178 in human acute myeloid leukemia cell lines
Dick, Taryn E, Hengst, Jeremy A, Fox, Todd E, Colledge, Ashley L, Kale, Vijay P, Sung, Shen-Shu, Sharma, Arun, Amin, Shantu, Loughran, Jr, Thomas P, Kester, Mark, Wang, Hong-Gang, Yun, Jong K
Published in The Journal of pharmacology and experimental therapeutics (01.03.2015)
Published in The Journal of pharmacology and experimental therapeutics (01.03.2015)
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Journal Article
The Nature of the Catalytic Domain of 2′-5′-Oligoadenylate Synthetases
Sarkar, Saumendra N., Ghosh, Arundhati, Wang, Hong-Wu, Sung, Shen-Shu, Sen, Ganes C.
Published in The Journal of biological chemistry (03.09.1999)
Published in The Journal of biological chemistry (03.09.1999)
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Journal Article
Molecular dynamics simulations of β-hairpin folding
Wang, Hongwu, Varady, Judith, Ng, Lily, Sung, Shen-Shu
Published in Proteins, structure, function, and bioinformatics (15.11.1999)
Published in Proteins, structure, function, and bioinformatics (15.11.1999)
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