Haploinsufficiency of RREB1 causes a Noonan-like RASopathy via epigenetic reprogramming of RAS-MAPK pathway genes
Kent, Oliver A., Saha, Manipa, Coyaud, Etienne, Burston, Helen E., Law, Napoleon, Dadson, Keith, Chen, Sujun, Laurent, Estelle M., St-Germain, Jonathan, Sun, Ren X., Matsumoto, Yoshinori, Cowen, Justin, Montgomery-Song, Aaryn, Brown, Kevin R., Ishak, Charles, Rose, Jose La, De Carvalho, Daniel D., He, Housheng Hansen, Raught, Brian, Billia, Filio, Kannu, Peter, Rottapel, Robert
Published in Nature communications (16.09.2020)
Published in Nature communications (16.09.2020)
Get full text
Journal Article
Human colorectal cancer-on-chip model to study the microenvironmental influence on early metastatic spread
Strelez, Carly, Chilakala, Sujatha, Ghaffarian, Kimya, Lau, Roy, Spiller, Erin, Ung, Nolan, Hixon, Danielle, Yoon, Ah Young, Sun, Ren X., Lenz, Heinz-Josef, Katz, Jonathan E., Mumenthaler, Shannon M.
Published in iScience (21.05.2021)
Published in iScience (21.05.2021)
Get full text
Journal Article
Inhibition of relaxin autocrine signaling confers therapeutic vulnerability in ovarian cancer
Burston, Helen E, Kent, Oliver A, Communal, Laudine, Udaskin, Molly L, Sun, Ren X, Brown, Kevin R, Jung, Euihye, Francis, Kyle E, La Rose, Jose, Lowitz, Joshua, Drapkin, Ronny, Mes-Masson, Anne-Marie, Rottapel, Robert
Published in The Journal of clinical investigation (01.04.2021)
Published in The Journal of clinical investigation (01.04.2021)
Get full text
Journal Article
Anti-EGFR Therapy Induces EGF Secretion by Cancer-Associated Fibroblasts to Confer Colorectal Cancer Chemoresistance
Garvey, Colleen M., Lau, Roy, Sanchez, Alyssa, Sun, Ren X., Fong, Emma J., Doche, Michael E., Chen, Oscar, Jusuf, Anthony, Lenz, Heinz-Josef, Larson, Brent, Mumenthaler, Shannon M.
Published in Cancers (28.05.2020)
Published in Cancers (28.05.2020)
Get full text
Journal Article
A controlled trial of HNSCC patient‐derived xenografts reveals broad efficacy of PI3Kα inhibition in controlling tumor growth
Ruicci, Kara M., Meens, Jalna, Sun, Ren X., Rizzo, Giananthony, Pinto, Nicole, Yoo, John, Fung, Kevin, MacNeil, Danielle, Mymryk, Joe S., Barrett, John W., Boutros, Paul C., Ailles, Laurie, Nichols, Anthony C.
Published in International journal of cancer (15.10.2019)
Published in International journal of cancer (15.10.2019)
Get full text
Journal Article
Paradoxical androgen receptor regulation by small molecule enantiomers
Patsch, Katherin, Liu, Chao, Zapotoczny, Grzegorz, Sun, Yuanye, Sura, Harish, Ung, Nolan, Sun, Ren X., Haliday, Bethany, Yu, Chen, Aljehani, Mayada, Lee, Jerry S. H., Kashemirov, Boris A., Agus, David B., McKenna, Charles E., Ruderman, Daniel
Published in Proceedings of the National Academy of Sciences - PNAS (23.03.2021)
Published in Proceedings of the National Academy of Sciences - PNAS (23.03.2021)
Get full text
Journal Article
Comparison of Cell and Organoid-Level Analysis of Patient-Derived 3D Organoids to Evaluate Tumor Cell Growth Dynamics and Drug Response
Kim, Seungil, Choung, Sarah, Sun, Ren X., Ung, Nolan, Hashemi, Natasha, Fong, Emma J., Lau, Roy, Spiller, Erin, Gasho, Jordan, Foo, Jasmine, Mumenthaler, Shannon M.
Published in SLAS discovery (01.08.2020)
Published in SLAS discovery (01.08.2020)
Get full text
Journal Article
PI3K/AKT/mTOR inhibition in combination with doxorubicin is an effective therapy for leiomyosarcoma
Babichev, Yael, Kabaroff, Leah, Datti, Alessandro, Uehling, David, Isaac, Methvin, Al-Awar, Rima, Prakesch, Michael, Sun, Ren X, Boutros, Paul C, Venier, Rosemarie, Dickson, Brendan C, Gladdy, Rebecca A
Published in Journal of translational medicine (08.03.2016)
Published in Journal of translational medicine (08.03.2016)
Get full text
Journal Article
Spleen tyrosine kinase expression is correlated with human papillomavirus in head and neck cancer
Black, Morgan, Ghasemi, Farhad, Sun, Ren X., Stecho, William, Datti, Alessandro, Meens, Jalna, Pinto, Nicole, Ruicci, Kara M., Khan, M. Imran, Han, Myung Woul, Shaikh, Mushfiq, Yoo, John, Fung, Kevin, MacNeil, Danielle, Palma, David A., Winquist, Eric, Howlett, Christopher J., Mymryk, Joe S., Ailles, Laurie, Boutros, Paul C., Barrett, John W., Nichols, Anthony C.
Published in Oral oncology (01.02.2020)
Published in Oral oncology (01.02.2020)
Get full text
Journal Article
High-throughput testing in head and neck squamous cell carcinoma identifies agents with preferential activity in human papillomavirus-positive or negative cell lines
Ghasemi, Farhad, Black, Morgan, Sun, Ren X, Vizeacoumar, Frederick, Pinto, Nicole, Ruicci, Kara M, Yoo, John, Fung, Kevin, MacNeil, Danielle, Palma, David A, Winquist, Eric, Mymryk, Joe S, Ailles, Laurie A, Datti, Alessandro, Barrett, John W, Boutros, Paul C, Nichols, Anthony C
Published in Oncotarget (25.05.2018)
Published in Oncotarget (25.05.2018)
Get full text
Journal Article
Comparative toxicoproteogenomics of mouse and rat liver identifies TCDD-resistance genes
Prokopec, Stephenie D., Lu, Aileen, Lee, Sandy Che-Eun S., Yao, Cindy Q., Sun, Ren X., Watson, John D., Soliymani, Rabah, de Borja, Richard, Wong, Ada, Sam, Michelle, Zuzarte, Philip, McPherson, John D., Okey, Allan B., Pohjanvirta, Raimo, Boutros, Paul C.
Published in Archives of toxicology (01.10.2019)
Published in Archives of toxicology (01.10.2019)
Get full text
Journal Article
Compendium of TCDD-mediated transcriptomic response datasets in mammalian model systems
Prokopec, Stephenie D, Houlahan, Kathleen E, Sun, Ren X, Watson, John D, Yao, Cindy Q, Lee, Jamie, P'ng, Christine, Pang, Renee, Wu, Alexander H, Chong, Lauren C, Smith, Ashley B, Harding, Nicholas J, Moffat, Ivy D, Lindén, Jere, Lensu, Sanna, Okey, Allan B, Pohjanvirta, Raimo, Boutros, Paul C
Published in BMC genomics (13.01.2017)
Published in BMC genomics (13.01.2017)
Get full text
Journal Article
Transcriptional profiling of rat white adipose tissue response to 2,3,7,8-tetrachlorodibenzo-ρ-dioxin
Houlahan, Kathleen E., Prokopec, Stephenie D., Sun, Ren X., Moffat, Ivy D., Lindén, Jere, Lensu, Sanna, Okey, Allan B., Pohjanvirta, Raimo, Boutros, Paul C.
Published in Toxicology and applied pharmacology (15.10.2015)
Published in Toxicology and applied pharmacology (15.10.2015)
Get full text
Journal Article
Cross-species transcriptomic analysis elucidates constitutive aryl hydrocarbon receptor activity
Sun, Ren X, Chong, Lauren C, Simmons, Trent T, Houlahan, Kathleen E, Prokopec, Stephenie D, Watson, John D, Moffat, Ivy D, Lensu, Sanna, Lindén, Jere, P'ng, Christine, Okey, Allan B, Pohjanvirta, Raimo, Boutros, Paul C
Published in BMC genomics (03.12.2014)
Published in BMC genomics (03.12.2014)
Get full text
Journal Article
Integration of Patient-Derived Organoids and Organ-on-Chip Systems: Investigating Colorectal Cancer Invasion within the Mechanical and GABAergic Tumor Microenvironment
Strelez, Carly, Perez, Rachel, Chlystek, John S, Cherry, Christopher, Yoon, Ah Young, Haliday, Bethany, Shah, Curran, Ghaffarian, Kimya, Sun, Ren X, Jiang, Hannah, Lau, Roy, Schatz, Aaron, Lenz, Heinz-Josef, Katz, Jonathan E, Mumenthaler, Shannon M
Published in bioRxiv (17.09.2023)
Published in bioRxiv (17.09.2023)
Get full text
Journal Article
BPG: Seamless, automated and interactive visualization of scientific data
P'ng, Christine, Green, Jeffrey, Chong, Lauren C, Waggott, Daryl, Prokopec, Stephenie D, Shamsi, Mehrdad, Nguyen, Francis, Mak, Denise Y F, Lam, Felix, Albuquerque, Marco A, Wu, Ying, Jung, Esther H, Starmans, Maud H W, Chan-Seng-Yue, Michelle A, Yao, Cindy Q, Liang, Bianca, Lalonde, Emilie, Haider, Syed, Simone, Nicole A, Sendorek, Dorota, Chu, Kenneth C, Moon, Nathalie C, Fox, Natalie S, Grzadkowski, Michal R, Harding, Nicholas J, Fung, Clement, Murdoch, Amanda R, Houlahan, Kathleen E, Wang, Jianxin, Garcia, David R, de Borja, Richard, Sun, Ren X, Lin, Xihui, Chen, Gregory M, Lu, Aileen, Shiah, Yu-Jia, Zia, Amin, Kearns, Ryan, Boutros, Paul C
Published in BMC bioinformatics (21.01.2019)
Published in BMC bioinformatics (21.01.2019)
Get full text
Journal Article
Abstract 5339: Paradoxical androgen receptor regulation by small molecule enantiomers
Patsch, Katherin, Liu, Chao, Kashemirov, Boris, Sura, Harish, Zapotoczny, Grzegorz, Sun, Yuanye, Shah, Pavan P., Katz, Jonathan E., Chilakala, Sujatha, Joo, Ah Young, Ung, Nolan, Aljehani, Maya, Sun, Ren X., Agus, David B., Ruderman, Daniel, McKenna, Charles E.
Published in Cancer research (Chicago, Ill.) (15.08.2020)
Published in Cancer research (Chicago, Ill.) (15.08.2020)
Get full text
Journal Article
Abstract 1507: Involvement of GABAergic signaling in enhanced tumor cell invasion in a mechanically dynamic tumor microenvironment
Strelez, Carly, Perez, Rachel, Chlystek, John S., Cherry, Christopher, Haliday, Bethany, Yoon, Ah Young, Shah, Curran, Sun, Ren X., Lau, Roy, Schatz, Aaron, Neman, Josh, Josef-Lenz, Heinz, Katz, Jonathan, Mumenthaler, Shannon M.
Published in Cancer research (Chicago, Ill.) (22.03.2024)
Published in Cancer research (Chicago, Ill.) (22.03.2024)
Get full text
Journal Article
Identifying TCDD-resistance genes via murine and rat comparative genomics and transcriptomics
Prokopec, Stephenie D, Lu, Aileen, Lee, Sandy Che-Eun S, Yao, Cindy Q, Sun, Ren X, Watson, John D, De Borja, Richard, Wong, Ada, Sam, Michelle, Zuzarte, Philip, Mcpherson, John D, Okey, Allan B, Pohjanvirta, Raimo, Boutros, Paul C
Published in bioRxiv (08.04.2019)
Published in bioRxiv (08.04.2019)
Get full text
Paper