Development of a Scalable Synthetic Process for DG-051B, A First-in-Class Inhibitior of LTA4H
Enache, Livia A, Kennedy, Isaac, Sullins, David W, Chen, Wei, Ristic, Dragan, Stahl, Glenn L, Dzekhtser, Sergey, Erickson, Robert A, Yan, Changren, Muellner, Frank W, Krohn, Michael D, Winger, Jennifer, Sandanayaka, Vincent, Singh, Jasbir, Zembower, David E, Kiselyov, Alex S
Published in Organic process research & development (20.11.2009)
Published in Organic process research & development (20.11.2009)
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Journal Article
Synthesis and structural assignment of two major metabolites of the LTA4H inhibitor DG-051
Enache, Livia A., Zhang, Jun, Sullins, David W., Kennedy, Isaac, Onua, Emmanuel, Zembower, David E., Muellner, Frank W., Singh, Jasbir, Kiselyov, Alex S.
Published in Bioorganic & medicinal chemistry letters (15.11.2009)
Published in Bioorganic & medicinal chemistry letters (15.11.2009)
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Journal Article
Seven new didemnins from the marine tunicate Trididemnum solidum
Sakai, Ryuichi, Stroh, Justin G, Sullins, David W, Rinehart, Kenneth L
Published in Journal of the American Chemical Society (01.04.1995)
Published in Journal of the American Chemical Society (01.04.1995)
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Journal Article
Synthesis and properties of the eight isostatine stereoisomers
Rinehart, Kenneth L, Sakai, Ryuichi, Kishore, Vimal, Sullins, David W, Li, Kai Ming
Published in Journal of organic chemistry (01.05.1992)
Published in Journal of organic chemistry (01.05.1992)
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Journal Article
Discovery of 4-[(2S)-2-{[4-(4-Chlorophenoxy)phenoxy]methyl}-1-pyrrolidinyl]butanoic Acid (DG-051) as a Novel Leukotriene A4 Hydrolase Inhibitor of Leukotriene B4 Biosynthesis
Sandanayaka, Vincent, Mamat, Bjorn, Mishra, Rama K, Winger, Jennifer, Krohn, Michael, Zhou, Li-Ming, Keyvan, Monica, Enache, Livia, Sullins, David, Onua, Emmanuel, Zhang, Jun, Halldorsdottir, Gudrun, Sigthorsdottir, Heida, Thorlaksdottir, Audur, Sigthorsson, Gudmundur, Thorsteinnsdottir, Margret, Davies, Douglas R, Stewart, Lance J, Zembower, David E, Andresson, Thorkell, Kiselyov, Alex S, Singh, Jasbir, Gurney, Mark E
Published in Journal of medicinal chemistry (28.01.2010)
Published in Journal of medicinal chemistry (28.01.2010)
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Journal Article
Total synthesis of the methanogenic cofactors methanofuran and methanofuran b
Sullins, David W, Bobik, Thomas A, Wolfe, Ralph S, Rinehart, Kenneth L
Published in Journal of the American Chemical Society (01.07.1993)
Published in Journal of the American Chemical Society (01.07.1993)
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Journal Article
(4aS,7S,7aR)-Nepetalactam and (4aS,7S,7aR)-2-[(3R,4R,4aR,7S,7aR)-octahydro-4,7-dimethyl-1-oxocyclopenta[c]pyran-3-yl]nepetalactam. Nitrogen analogs of nepetalactone and nepetalic .psi.-anhydride
Eisenbraun, Edmund J, Sullins, David W, Browne, Clinton E, Shoolery, James N
Published in Journal of organic chemistry (01.08.1988)
Published in Journal of organic chemistry (01.08.1988)
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Journal Article
Erratum - " Didemnins and Tunichlorin: Novel Natural Products from the Marine Tunicate Trididemnum solidum
Rinehart, Kenneth L, Kishore, Vimal, Bible, Keith C, Sakai, Ryuichi, Sullins, David W, Li, Kai-Ming
Published in Journal of natural products (Washington, D.C.) (01.05.1988)
Published in Journal of natural products (Washington, D.C.) (01.05.1988)
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Journal Article
Certification revisited : American optometric association
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Conference Proceeding
Journal Article
Total synthesis of didemnins A, B, and C
Rinehart, Kenneth L, Kishore, Vimal, Nagarajan, Srinivasan, Lake, Robin J, Gloer, James B, Bozich, Frank A, Li, Kai Ming, Maleczka, Robert E, Todsen, William L
Published in Journal of the American Chemical Society (01.10.1987)
Published in Journal of the American Chemical Society (01.10.1987)
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Journal Article