Population Differences in Major Functional Polymorphisms of Pharmacokinetics/pharmacodynamics-related Genes in Eastern Asians and Europeans: Implications in the Clinical Trials for Novel Drug Development
Kurose, Kouichi, Sugiyama, Emiko, Saito, Yoshiro
Published in DRUG METABOLISM AND PHARMACOKINETICS (2012)
Published in DRUG METABOLISM AND PHARMACOKINETICS (2012)
Get full text
Journal Article
Pharmacokinetics of Gemcitabine in Japanese Cancer Patients: The Impact of a Cytidine Deaminase Polymorphism
SUGIYAMA, Emiko, KANIWA, Nahoko, FURUSE, Junji, ISHII, Hiroshi, YOSHIDA, Teruhiko, UENO, Hideki, OKUSAKA, Takuji, SAIJO, Nagahiro, KIM, Su-Ryang, KIKURA-HANAJIRI, Ruri, HASEGAWA, Ryuichi, MAEKAWA, Keiko, SAITO, Yoshiro, OZAWA, Shogo, SAWADA, Jun-Ichi, KAMATANI, Naoyuki
Published in Journal of clinical oncology (01.01.2007)
Published in Journal of clinical oncology (01.01.2007)
Get full text
Journal Article
Development of a Rapid and Inexpensive Assay for Detecting a Surrogate Genetic Polymorphism of HLA-B58:01: A Partially Predictive but Useful Biomarker for Allopurinol-related Stevens-Johnson Syndrome/toxic Epidermal Necrolysis in Japanese
Maekawa, Keiko, Nishikawa, Jun, Kaniwa, Nahoko, Sugiyama, Emiko, Koizumi, Tomoko, Kurose, Kouichi, Tohkin, Masahiro, Saito, Yoshiro
Published in DRUG METABOLISM AND PHARMACOKINETICS (2012)
Published in DRUG METABOLISM AND PHARMACOKINETICS (2012)
Get full text
Journal Article
Drugs causing severe ocular surface involvements in Japanese patients with Stevens–Johnson syndrome/toxic epidermal necrolysis
Kaniwa, Nahoko, Ueta, Mayumi, Nakamura, Ryosuke, Okamoto-Uchida, Yoshimi, Sugiyama, Emiko, Maekawa, Keiko, Takahashi, Yukitoshi, Furuya, Hirokazu, Yagami, Akiko, Matsukura, Setsuko, Ikezawa, Zenro, Matsunaga, Kayoko, Sotozono, Chie, Aihara, Michiko, Kinoshita, Shigeru, Saito, Yoshiro
Published in Allergology international (01.10.2015)
Published in Allergology international (01.10.2015)
Get full text
Journal Article
Substrate-Dependent Functional Alterations of Seven CYP2C9 Variants Found in Japanese Subjects
MAEKAWA, Keiko, HARAKAWA, Noriko, MIYATA, Toshiyuki, SAITO, Yoshiro, SAWADA, Jun-Ichi, SUGIYAMA, Emiko, TOHKIN, Masahiro, KIM, Su-Ryang, KANIWA, Nahoko, KATORI, Noriko, HASEGAWA, Ryuichi, YASUDA, Kazuki, KAMIDE, Kei
Published in Drug metabolism and disposition (01.09.2009)
Published in Drug metabolism and disposition (01.09.2009)
Get full text
Journal Article
Identification of a Predictive Biomarker for Hematologic Toxicities of Gemcitabine
MATSUBARA, Junichi, ONO, Masaya, SAWADA, Junichi, HONDA, Kazufumi, SAKUMA, Tomohiro, CHIBA, Tsutomu, SAIJO, Nagahiro, HIROHASHI, Setsuo, YAMADA, Tesshi, NEGISHI, Ayako, UENO, Hideki, OKUSAKA, Takuji, FURUSE, Junji, FURUTA, Koh, SUGIYAMA, Emiko, SAITO, Yoshiro, KANIWA, Nahoko
Published in Journal of clinical oncology (01.05.2009)
Published in Journal of clinical oncology (01.05.2009)
Get full text
Journal Article
Survival Prediction for Pancreatic Cancer Patients Receiving Gemcitabine Treatment
Matsubara, Junichi, Ono, Masaya, Honda, Kazufumi, Negishi, Ayako, Ueno, Hideki, Okusaka, Takuji, Furuse, Junji, Furuta, Koh, Sugiyama, Emiko, Saito, Yoshiro, Kaniwa, Nahoko, Sawada, Junichi, Shoji, Ayako, Sakuma, Tomohiro, Chiba, Tsutomu, Saijo, Nagahiro, Hirohashi, Setsuo, Yamada, Tesshi
Published in Molecular & cellular proteomics (01.04.2010)
Published in Molecular & cellular proteomics (01.04.2010)
Get full text
Journal Article
Ethnic Differences of two Non-synonymous Single Nucleotide Polymorphisms in CDA Gene
Sugiyama, Emiko, Lee, Su-Jun, Lee, Sang Seop, Kim, Woo-Young, Kim, Su-Ryang, Tohkin, Masahiro, Hasegawa, Ryuichi, Okuda, Haruhiro, Kawamoto, Manabu, Kamatani, Naoyuki, Sawada, Jun-ichi, Kaniwa, Nahoko, Saito, Yoshiro, Shin, Jae-Gook
Published in DRUG METABOLISM AND PHARMACOKINETICS (01.01.2009)
Published in DRUG METABOLISM AND PHARMACOKINETICS (01.01.2009)
Get full text
Journal Article
Twenty Novel Genetic Variations and Haplotype Structures of the DCK Gene Encoding Human Deoxycytidine Kinase (dCK)
Kim, Su-Ryang, Saito, Yoshiro, Maekawa, Keiko, Sugiyama, Emiko, Kaniwa, Nahoko, Ueno, Hideki, Okusaka, Takuji, Ikeda, Masafumi, Morizane, Chigusa, Yamamoto, Noboru, Yoshida, Teruhiko, Kamatani, Naoyuki, Furuse, Junji, Ishii, Hiroshi, Saijo, Nagahiro, Ozawa, Shogo, Sawada, Jun-ichi
Published in DRUG METABOLISM AND PHARMACOKINETICS (01.01.2008)
Published in DRUG METABOLISM AND PHARMACOKINETICS (01.01.2008)
Get full text
Journal Article
Thirty Novel Genetic Variations in the SLC29A1 Gene Encoding Human Equilibrative Nucleoside Transporter 1 (hENT1)
Kim, SuRyang, Saito, Yoshiro, Maekawa, Keiko, Sugiyama, Emiko, Kaniwa, Nahoko, Ueno, Hideki, Okusaka, Takuji, Morizane, Chigusa, Yamamoto, Noboru, Ikeda, Masafumi, Yoshida, Teruhiko, Minami, Hironobu, Furuse, Junji, Ishii, Hiroshi, Saijo, Nagahiro, Kamatani, Naoyuki, Ozawa, Shogo, Sawada, Junichi
Published in DRUG METABOLISM AND PHARMACOKINETICS (01.01.2006)
Published in DRUG METABOLISM AND PHARMACOKINETICS (01.01.2006)
Get full text
Journal Article
Genetic Polymorphisms of Copper-and Platinum Drug-efflux Transporters ATP7A and ATP7B in Japanese Cancer Patients
Fukushima-Uesaka, Hiromi, Saito, Yoshiro, Maekawa, Keiko, Kurose, Kouichi, Sugiyama, Emiko, Katori, Noriko, Kaniwa, Nahoko, Hasegawa, Ryuichi, Hamaguchi, Tetsuya, Eguchi-Nakajima, Takako, Kato, Ken, Yamada, Yasuhide, Shimada, Yasuhiro, Yoshida, Teruhiko, Yamamoto, Noboru, Nokihara, Hiroshi, Kunitoh, Hideo, Ohe, Yuichiro, Tamura, Tomohide, Ura, Takashi, Saito, Miyuki, Muro, Kei, Doi, Toshihiko, Fuse, Nozomu, Yoshino, Takayuki, Ohtsu, Atsushi, Saijo, Nagahiro, Matsumura, Yasuhiro, Okuda, Haruhiro, Sawada, Jun-ichi
Published in DRUG METABOLISM AND PHARMACOKINETICS (01.01.2009)
Published in DRUG METABOLISM AND PHARMACOKINETICS (01.01.2009)
Get full text
Journal Article
How is autonomic nervous system activity in subjects who are sleepy but are unable to sleep in the daytime?
MORISHIMA, Hiroko, SUGIYAMA, Emiko, MATSUSHITA, Masateru, URUHA, Shigehiko, ITO, Satoko, ABE, Yukari, NISHITANI, Momoko, WATANABE, Takuya, SUGANUMA, Nakamori, YAMAMURA, Schuhei, YANAGI, Kentarou, SHIGEDO, Yoshihisa, KUMANO-GO, Takayuki, ADACHI, Hiroyoshi, MIKAMI, Akira, SUGITA, Yoshiro, TAKEDA, Masatoshi
Published in Sleep and biological rhythms (01.01.2009)
Published in Sleep and biological rhythms (01.01.2009)
Get full text
Journal Article
Severe Drug Toxicity Associated with a Single-Nucleotide Polymorphism of the Cytidine Deaminase Gene in a Japanese Cancer Patient Treated with Gemcitabine plus Cisplatin
YONEMORI, Kan, UENO, Hideki, KIM, Su-Ryang, KIKURA-HANAJIRI, Ruri, HASEGAWA, Ryuichi, SAITO, Yoshiro, OZAWA, Shogo, KANIWA, Nahoko, SAWADA, Jun-Ichi, OKUSAKA, Takuji, YAMAMOTO, Noboru, IKEDA, Masafumi, SAIJO, Nagahiro, YOSHIDA, Teruhiko, ISHII, Hiroshi, FURUSE, Junji, SUGIYAMA, Emiko
Published in Clinical cancer research (01.04.2005)
Published in Clinical cancer research (01.04.2005)
Get full text
Journal Article
Independent strong association of HLA-A02:06 and HLA-B44:03 with cold medicine-related Stevens-Johnson syndrome with severe mucosal involvement
Ueta, Mayumi, Kaniwa, Nahoko, Sotozono, Chie, Tokunaga, Katsushi, Saito, Yoshiro, Sawai, Hiromi, Miyadera, Hiroko, Sugiyama, Emiko, Maekawa, Keiko, Nakamura, Ryosuke, Nagato, Masaki, Aihara, Michiko, Matsunaga, Kayoko, Takahashi, Yukitoshi, Furuya, Hirokazu, Muramatsu, Masaaki, Ikezawa, Zenrou, Kinoshita, Shigeru
Published in Scientific reports (30.04.2014)
Published in Scientific reports (30.04.2014)
Get full text
Journal Article
Structural significance of residues 158–160 in the H3N2 hemagglutnin globular head: A computational study with implications in viral evolution and infection
Cueno, Marni E., Shiotsu, Hayato, Nakano, Karin, Sugiyama, Emiko, Kikuta, Mari, Usui, Rikuya, Oya, Riku, Imai, Kenichi
Published in Journal of molecular graphics & modelling (01.06.2019)
Published in Journal of molecular graphics & modelling (01.06.2019)
Get full text
Journal Article
IKZF1 , a new susceptibility gene for cold medicine–related Stevens-Johnson syndrome/toxic epidermal necrolysis with severe mucosal involvement
Ueta, Mayumi, MD, PhD, Sawai, Hiromi, PhD, Sotozono, Chie, MD, PhD, Hitomi, Yuki, PhD, Kaniwa, Nahoko, PhD, Kim, Mee Kum, MD, PhD, Seo, Kyoung Yul, MD, PhD, Yoon, Kyung-Chul, MD, PhD, Joo, Choun-Ki, MD, PhD, Kannabiran, Chitra, PhD, Wakamatsu, Tais Hitomi, MD, PhD, Sangwan, Virender, MD, PhD, Rathi, Varsha, MD, PhD, Basu, Sayan, MD, PhD, Ozeki, Takeshi, PhD, Mushiroda, Taisei, PhD, Sugiyama, Emiko, PhD, Maekawa, Keiko, PhD, Nakamura, Ryosuke, PhD, Aihara, Michiko, MD, PhD, Matsunaga, Kayoko, MD, PhD, Sekine, Akihiro, PhD, Gomes, José Álvaro Pereira, MD, PhD, Hamuro, Junji, PhD, Saito, Yoshiro, PhD, Kubo, Michiaki, MD, PhD, Kinoshita, Shigeru, MD, PhD, Tokunaga, Katsushi, PhD
Published in Journal of allergy and clinical immunology (01.06.2015)
Published in Journal of allergy and clinical immunology (01.06.2015)
Get full text
Journal Article
Predictive Genomic Markers for Severe Adverse Drug Reactions
Saito, Yoshiro, Kodama, Susumu, Sugiyama, Emiko, Nakamura, Ryosuke
Published in YAKUGAKU ZASSHI (01.04.2015)
Published in YAKUGAKU ZASSHI (01.04.2015)
Get full text
Journal Article
Specific HLA types are associated with antiepileptic drug-induced Stevens-Johnson syndrome and toxic epidermal necrolysis in Japanese subjects
Kaniwa, Nahoko, Sugiyama, Emiko, Saito, Yoshiro, Kurose, Kouichi, Maekawa, Keiko, Hasegawa, Ryuichi, Furuya, Hirokazu, Ikeda, Hiroko, Takahashi, Yukitoshi, Muramatsu, Masaaki, Tohkin, Masahiro, Ozeki, Takeshi, Mushiroda, Taisei, Kubo, Michiaki, Kamatani, Naoyuki, Abe, Masamichi, Yagami, Akiko, Ueta, Mayumi, Sotozono, Chie, Kinoshita, Shigeru, Ikezawa, Zenro, Matsunaga, Kayoko, Aihara, Michiko
Published in Pharmacogenomics (01.11.2013)
Published in Pharmacogenomics (01.11.2013)
Get full text
Journal Article
Population Pharmacokinetics of Gemcitabine and Its Metabolite in Japanese Cancer Patients: Impact of Genetic Polymorphisms
Sugiyama, Emiko, Kaniwa, Nahoko, Kim, Su-Ryang, Hasegawa, Ryuichi, Saito, Yoshiro, Ueno, Hideki, Okusaka, Takuji, Ikeda, Masafumi, Morizane, Chigusa, Kondo, Shunsuke, Yamamoto, Noboru, Tamura, Tomohide, Furuse, Junji, Ishii, Hiroshi, Yoshida, Teruhiko, Saijo, Nagahiro, Sawada, Jun-Ichi
Published in Clinical pharmacokinetics (01.08.2010)
Published in Clinical pharmacokinetics (01.08.2010)
Get full text
Journal Article