Search Results - "Sugimoto, Masahiro"

Salivary metabolomics for cancer detection by Sugimoto, Masahiro

“…: Saliva is an ideal biofluid that can be collected in a noninvasive manner, enabling safe and frequent screening of various diseases. Recent studies have…”

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Editorial of Special Issue “Metabolomic Analysis in Health and Diseases” by Sugimoto, Masahiro

“…Metabolomics, a quantitative omics technology that simultaneously profiles hundreds of metabolites, has been used to explore new biomarkers and elucidate the…”

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Existence of SARS-CoV-2 Entry Molecules in the Oral Cavity by Sakaguchi, Wakako, Kubota, Nobuhisa, Shimizu, Tomoko, Saruta, Juri, Fuchida, Shinya, Kawata, Akira, Yamamoto, Yuko, Sugimoto, Masahiro, Yakeishi, Mayumi, Tsukinoki, Keiichi

“…The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) receptor, angiotensin-converting enzyme 2 (ACE2), transmembrane protease serine 2 (TMPRSS2),…”

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Electrical properties of α-Ir2O3/α-Ga2O3 pn heterojunction diode and band alignment of the heterostructure by Kan, Shin-ichi, Takemoto, Shu, Kaneko, Kentaro, Takahashi, Isao, Sugimoto, Masahiro, Shinohe, Takashi, Fujita, Shizuo

“…Corundum-structured iridium oxide (α-Ir2O3), showing p-type conductivity, is a strong candidate to form high-quality pn heterojunctions with α-Ga2O3. We…”

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Biomarkers for Alzheimer’s Disease in the Current State: A Narrative Review by Gunes, Serafettin, Aizawa, Yumi, Sugashi, Takuma, Sugimoto, Masahiro, Rodrigues, Pedro Pereira

“…Alzheimer’s disease (AD) has become a problem, owing to its high prevalence in an aging society with no treatment available after onset. However, early…”

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Mathematical simulation of tumour angiogenesis: angiopoietin balance is a key factor in vessel growth and regression by Yanagisawa, Hayato, Sugimoto, Masahiro, Miyashita, Tomoyuki

“…Excessive tumour growth results in a hypoxic environment around cancer cells, thus inducing tumour angiogenesis, which refers to the generation of new blood…”

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Robust volcano plot: identification of differential metabolites in the presence of outliers by Kumar, Nishith, Hoque, Md. Aminul, Sugimoto, Masahiro

“…The identification of differential metabolites in metabolomics is still a big challenge and plays a prominent role in metabolomics data analyses. Metabolomics…”

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Global metabolic reprogramming of colorectal cancer occurs at adenoma stage and is induced by MYC by Satoh, Kiyotoshi, Yachida, Shinichi, Sugimoto, Masahiro, Oshima, Minoru, Nakagawa, Toshitaka, Akamoto, Shintaro, Tabata, Sho, Saitoh, Kaori, Kato, Keiko, Sato, Saya, Igarashi, Kaori, Aizawa, Yumi, Kajino-Sakamoto, Rie, Kojima, Yasushi, Fujishita, Teruaki, Enomoto, Ayame, Hirayama, Akiyoshi, Ishikawa, Takamasa, Taketo, Makoto Mark, Kushida, Yoshio, Haba, Reiji, Okano, Keiichi, Tomita, Masaru, Suzuki, Yasuyuki, Fukuda, Shinji, Aoki, Masahiro, Soga, Tomoyoshi

“…Cancer cells alter their metabolism for the production of precursors of macromolecules. However, the control mechanisms underlying this reprogramming are…”

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Salivary metabolomic biomarkers for non‐invasive lung cancer detection by Kajiwara, Naohiro, Kakihana, Masatoshi, Maeda, Junichi, Kaneko, Miku, Ota, Sana, Enomoto, Ayame, Ikeda, Norihiko, Sugimoto, Masahiro

“…Identifying novel biomarkers for early detection of lung cancer is crucial. Non‐invasively available saliva is an ideal biofluid for biomarker exploration;…”

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Salivary metabolites as novel independent predictors of radiation pneumonitis by Shiraishi, Sachika, Sugimoto, Masahiro, Tokuuye, Koichi

“…Purpose Radiotherapy is an integral treatment for non-small cell lung cancer (NSCLC); however, radiation-induced toxicities such as radiation pneumonitis (RP)…”

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Capillary electrophoresis mass spectrometry-based saliva metabolomics identified oral, breast and pancreatic cancer-specific profiles by Sugimoto, Masahiro, Wong, David T, Hirayama, Akiyoshi, Soga, Tomoyoshi, Tomita, Masaru

“…Saliva is a readily accessible and informative biofluid, making it ideal for the early detection of a wide range of diseases including cardiovascular, renal,…”

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Urinary charged metabolite profiling of colorectal cancer using capillary electrophoresis-mass spectrometry by Udo, Ryutaro, Katsumata, Kenji, Kuwabara, Hiroshi, Enomoto, Masanobu, Ishizaki, Tetsuo, Sunamura, Makoto, Nagakawa, Yuichi, Soya, Ryoko, Sugimoto, Masahiro, Tsuchida, Akihiko

“…Colorectal cancer (CRC) has increasing global prevalence and poor prognostic outcomes, and the development of low- or less invasive screening tests is urgently…”

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Discrimination of oral squamous cell carcinoma from oral lichen planus by salivary metabolomics by Ishikawa, Shigeo, Sugimoto, Masahiro, Edamatsu, Kaoru, Sugano, Ayako, Kitabatake, Kenichiro, Iino, Mitsuyoshi

“…Objective This study was conducted to distinguish salivary metabolites in oral squamous cell carcinoma (OSCC) from those in oral lichen planus (OLP) to…”

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High-throughput screening of salivary polyamine markers for discrimination of colorectal cancer by multisegment injection capillary electrophoresis tandem mass spectrometry by Igarashi, Kaori, Ota, Sana, Kaneko, Miku, Hirayama, Akiyoshi, Enomoto, Masanobu, Katumata, Kenji, Sugimoto, Masahiro, Soga, Tomoyoshi

“…•High-throughput screening salivary polyamines by MSI-CE-MS/MS was developed.•The choice of BGE and its spacer volume affected peak resolution among…”

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Kernel weighted least square approach for imputing missing values of metabolomics data by Kumar, Nishith, Hoque, Md. Aminul, Sugimoto, Masahiro

“…Mass spectrometry is a modern and sophisticated high-throughput analytical technique that enables large-scale metabolomic analyses. It yields a…”

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Discovery of lipid profiles in plasma‐derived extracellular vesicles as biomarkers for breast cancer diagnosis by Liu, Lin, Kawashima, Masahiro, Sugimoto, Masahiro, Sonomura, Kazuhiro, Pu, Fengling, Li, Wei, Takeda, Masashi, Goto, Takayuki, Kawaguchi, Kosuke, Sato, Taka‐Aki, Toi, Masakazu

“…Lipids are a major component of extracellular vesicles; however, their significance in tumorigenesis and progression has not been well elucidated. As we…”

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Identification of salivary metabolomic biomarkers for oral cancer screening by Ishikawa, Shigeo, Sugimoto, Masahiro, Kitabatake, Kenichiro, Sugano, Ayako, Nakamura, Marina, Kaneko, Miku, Ota, Sana, Hiwatari, Kana, Enomoto, Ayame, Soga, Tomoyoshi, Tomita, Masaru, Iino, Mitsuyoshi

“…The objective of this study was to explore salivary metabolite biomarkers by profiling both saliva and tumor tissue samples for oral cancer screening. Paired…”

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Computational simulation of liver fibrosis dynamics by Yoshizawa, Misa, Sugimoto, Masahiro, Tanaka, Minoru, Sakai, Yusuyuki, Nishikawa, Masaki

“…Liver fibrosis is a result of homeostasis breakdown caused by repetitive injury. The accumulation of collagens disrupts liver structure and function, which…”

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Salivary metabolomic biomarkers for esophageal and gastric cancers by liquid chromatography–mass spectrometry by Nakane, Kosuke, Yagi, Koichi, Yajima, Sho, Nomura, Sachiyo, Sugimoto, Masahiro, Seto, Yasuyuki

“…Early detection of esophageal and gastric cancers is essential for patients' prognosis; however, optimal noninvasive screening tests are currently not…”

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Quantitative Metabolome Profiling of Colon and Stomach Cancer Microenvironment by Capillary Electrophoresis Time-of-Flight Mass Spectrometry by Hirayama, Akiyoshi, Kami, Kenjiro, Sugimoto, Masahiro, Sugawara, Maki, Toki, Naoko, Onozuka, Hiroko, Kinoshita, Taira, Saito, Norio, Ochiai, Atsushi, Tomita, Masaru, Esumi, Hiroyasu, Soga, Tomoyoshi

“…Most cancer cells predominantly produce energy by glycolysis rather than oxidative phosphorylation via the tricarboxylic acid (TCA) cycle, even in the presence…”

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