AKR-501 (YM477) a novel orally-active thrombopoietin receptor agonist
Fukushima-Shintani, Mari, Suzuki, Ken-ichi, Iwatsuki, Yoshiyuki, Abe, Masaki, Sugasawa, Keizo, Hirayama, Fukushi, Kawasaki, Tomihisa, Nakahata, Tatsutoshi
Published in European journal of haematology (01.04.2009)
Published in European journal of haematology (01.04.2009)
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Journal Article
Synthesis and structure-activity relationships of a series of benzazepine derivatives as 5-HT2C receptor agonists
SHIMADA, Itsuro, MAENO, Kyoichi, TSUKAMOTO, Shin-Ichi, KONDOH, Yutaka, KAKU, Hidetaka, SUGASAWA, Keizo, KIMURA, Yasuharu, HATANAKA, Ken-Ichi, NAITOU, Yuki, WANIBUCHI, Fumikazu, SAKAMOTO, Shuichi
Published in Bioorganic & medicinal chemistry (15.03.2008)
Published in Bioorganic & medicinal chemistry (15.03.2008)
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Journal Article
Solution structures of a monodentate chiral lithium amide in the presence of lithium halide
Sugasawa, Keizo, Shindo, Mitsuru, Noguchi, Hiroshi, Koga, Kenji
Published in Tetrahedron letters (07.10.1996)
Published in Tetrahedron letters (07.10.1996)
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Journal Article
Stereoselective Reactions. XXXIV.1) Enantioselective Deprotonation of Prochiral 4-Substituted Cyclohexanones Using Chiral Bidentate Lithium Amides Having a Bulky Group Instead of a Phenyl Group on the Chiral Carbon
TORIYAMA, Masaharu, SUGASAWA, Keizo, MOTOHASHI, Shigeyasu, TOKUTAKE, Norio, KOGA, Kenji
Published in Chemical & pharmaceutical bulletin (2001)
Published in Chemical & pharmaceutical bulletin (2001)
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Journal Article
Novel strategy to boost oral anticoagulant activity of blood coagulation enzyme inhibitors based on biotransformation into hydrophilic conjugates
Ishihara, Tsukasa, Koga, Yuji, Mori, Kenichi, Sugasawa, Keizo, Iwatsuki, Yoshiyuki, Hirayama, Fukushi
Published in Bioorganic & medicinal chemistry (15.11.2014)
Published in Bioorganic & medicinal chemistry (15.11.2014)
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Journal Article
Direct Modulation of Microtubule Stability Contributes to Anthracene General Anesthesia
Emerson, Daniel J, Weiser, Brian P, Psonis, John, Liao, Zhengzheng, Taratula, Olena, Fiamengo, Ashley, Wang, Xiaozhao, Sugasawa, Keizo, Smith, Amos B, Eckenhoff, Roderic G, Dmochowski, Ivan J
Published in Journal of the American Chemical Society (10.04.2013)
Published in Journal of the American Chemical Society (10.04.2013)
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Journal Article
Improved Dose-Response Relationship of (+)-Discodermolide-Taxol Hybrid Congeners
Nadaradjane, Celine, Yang, Chia-Ping Huang, Rodriguez-Gabin, Alicia, Ye, Kenny, Sugasawa, Keizo, Atasoylu, Onur, Smith, Amos B, Horwitz, Susan Band, McDaid, Hayley M
Published in Journal of natural products (Washington, D.C.) (23.03.2018)
Published in Journal of natural products (Washington, D.C.) (23.03.2018)
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Journal Article
Discovery of N-[2-Hydroxy-6-(4-methoxybenzamido)phenyl]-4- (4-methyl-1,4-diazepan-1-yl)benzamide (Darexaban, YM150) as a Potent and Orally Available Factor Xa Inhibitor
Hirayama, Fukushi, Koshio, Hiroyuki, Ishihara, Tsukasa, Hachiya, Shunichiro, Sugasawa, Keizo, Koga, Yuji, Seki, Norio, Shiraki, Ryouta, Shigenaga, Takeshi, Iwatsuki, Yoshiyuki, Moritani, Yumiko, Mori, Kenichi, Kadokura, Takeshi, Kawasaki, Tomihisa, Matsumoto, Yuzo, Sakamoto, Shuichi, Tsukamoto, Shin-ichi
Published in Journal of medicinal chemistry (08.12.2011)
Published in Journal of medicinal chemistry (08.12.2011)
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Journal Article
Abstract 2789: Interaction of (+)-discodermolide-Taxol hybrids with microtubules
Yang, Chia-Ping H., Sugasawa, Keizo, Atasoylu, Onur, Smith, Amos B., Horwitz, Susan B.
Published in Cancer research (Chicago, Ill.) (15.04.2012)
Published in Cancer research (Chicago, Ill.) (15.04.2012)
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Journal Article
Pharmacological profile of AS1670542, a novel orally-active human thrombopoietin receptor agonist
Abe, Masaki, Suzuki, Ken-ichi, Sakata, Chinatsu, Sugasawa, Keizo, Hirayama, Fukushi, Koga, Yuji, Kawasaki, Tomihisa, Naganuma, Shin, Itoh, Hiroyuki
Published in European journal of pharmacology (10.01.2011)
Published in European journal of pharmacology (10.01.2011)
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Journal Article
피페라진 유도체
HOSOGAI NAOMI, TANABE DAISUKE, MIHARA HISASHI, MORITOMO HIROYUKI, YAMASHITA DAISUKE, YONETOKU YASUHIRO, OSODA KAZUHIKO, ASAI NORIO, SUGANE TAKASHI, MAENO KYOICHI, SUGASAWA KEIZO, SHIMIZU TAKAFUMI, MAKINO TAKUYA
Year of Publication 30.03.2018
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Year of Publication 30.03.2018
Patent
PIPERAZINE DERIVATIVE
SUGASAWA, Keizo, MAENO, Kyoichi, MIHARA, Hisashi, MAKINO, Takuya, OSODA, Kazuhiko, MORITOMO, Hiroyuki, HOSOGAI, Naomi, ASAI, Norio, YONETOKU, Yasuhiro, SHIMIZU, Takafumi, SUGANE, Takashi, YAMASHITA, Daisuke, TANABE, Daisuke
Year of Publication 09.02.2017
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Year of Publication 09.02.2017
Patent
Synthesis and structure–activity relationships of a series of benzazepine derivatives as 5-HT 2C receptor agonists
Shimada, Itsuro, Maeno, Kyoichi, Kondoh, Yutaka, Kaku, Hidetaka, Sugasawa, Keizo, Kimura, Yasuharu, Hatanaka, Ken-ichi, Naitou, Yuki, Wanibuchi, Fumikazu, Sakamoto, Shuichi, Tsukamoto, Shin-ichi
Published in Bioorganic & medicinal chemistry (2008)
Published in Bioorganic & medicinal chemistry (2008)
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Journal Article
YM477, a Novel Orally-Active Thrombopoietin Receptor Agonist
Suzuki, Ken-ichi, Abe, Masaki, Fukushima-Shintani, Mari, Sugasawa, Keizo, Hirayama, Fukushi, Kawasaki, Tomihisa, Hiramatsu, Hidefumi, Nakahata, Tatsutoshi
Published in Blood (16.11.2005)
Published in Blood (16.11.2005)
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Journal Article
AZOLECARBOXAMIDE COMPOUND OR SALT THEREOF
MATSUMOTO SHUNICHIRO, SHIN TAKASHI, SUGASAWA KEIZO, SUGA AKIRA, WATANABE TORU, KAWAGUCHI KENICHI, NOMURA TAKAHO, AZAMI HIDENORI, TANAHASHI MASAYUKI, SEO RYUSHI, ABE TOMOAKI
Year of Publication 28.06.2010
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Year of Publication 28.06.2010
Patent