Small nucleoli are a cellular hallmark of longevity
Tiku, Varnesh, Jain, Chirag, Raz, Yotam, Nakamura, Shuhei, Heestand, Bree, Liu, Wei, Späth, Martin, Suchiman, H. Eka. D., Müller, Roman-Ulrich, Slagboom, P. Eline, Partridge, Linda, Antebi, Adam
Published in Nature communications (30.08.2017)
Published in Nature communications (30.08.2017)
Get full text
Journal Article
Genetic and environmental influences interact with age and sex in shaping the human methylome
van Dongen, Jenny, Nivard, Michel G., Willemsen, Gonneke, Hottenga, Jouke-Jan, Helmer, Quinta, Dolan, Conor V., Ehli, Erik A., Davies, Gareth E., van Iterson, Maarten, Breeze, Charles E., Beck, Stephan, Suchiman, H. Eka, Jansen, Rick, van Meurs, Joyce B., Heijmans, Bastiaan T., Slagboom, P. Eline, Boomsma, Dorret I.
Published in Nature communications (07.04.2016)
Published in Nature communications (07.04.2016)
Get full text
Journal Article
DNA Methylation Landscapes of Human Fetal Development
Slieker, Roderick C, Roost, Matthias S, van Iperen, Liesbeth, Suchiman, H Eka D, Tobi, Elmar W, Carlotti, Françoise, de Koning, Eelco J P, Slagboom, P Eline, Heijmans, Bastiaan T, Chuva de Sousa Lopes, Susana M
Published in PLoS genetics (01.10.2015)
Published in PLoS genetics (01.10.2015)
Get full text
Journal Article
RNA sequencing data integration reveals an miRNA interactome of osteoarthritis cartilage
Coutinho de Almeida, Rodrigo, Ramos, Yolande F M, Mahfouz, Ahmed, den Hollander, Wouter, Lakenberg, Nico, Houtman, Evelyn, van Hoolwerff, Marcella, Suchiman, H Eka D, Rodríguez Ruiz, Alejandro, Slagboom, P Eline, Mei, Hailiang, Kiełbasa, Szymon M, Nelissen, Rob G H H, Reinders, Marcel, Meulenbelt, Ingrid
Published in Annals of the rheumatic diseases (01.02.2019)
Published in Annals of the rheumatic diseases (01.02.2019)
Get full text
Journal Article
Elucidating mechano-pathology of osteoarthritis: transcriptome-wide differences in mechanically stressed aged human cartilage explants
Houtman, Evelyn, Tuerlings, Margo, Riechelman, Janne, Suchiman, Eka H. E. D, van der Wal, Robert J. P, Nelissen, Rob G. H. H, Mei, Hailiang, Ramos, Yolande F. M, Coutinho de Almeida, Rodrigo, Meulenbelt, Ingrid
Published in Arthritis research & therapy (16.08.2021)
Published in Arthritis research & therapy (16.08.2021)
Get full text
Journal Article
DNA methylation and transcriptional trajectories during human development and reprogramming of isogenic pluripotent stem cells
Roost, Matthias S., Slieker, Roderick C., Bialecka, Monika, van Iperen, Liesbeth, Gomes Fernandes, Maria M., He, Nannan, Suchiman, H. Eka D., Szuhai, Karoly, Carlotti, Françoise, de Koning, Eelco J. P., Mummery, Christine L., Heijmans, Bastiaan T., Chuva de Sousa Lopes, Susana M.
Published in Nature communications (13.10.2017)
Published in Nature communications (13.10.2017)
Get full text
Journal Article
TCTEX1D1 is a genetic modifier of disease progression in Duchenne muscular dystrophy
Spitali, Pietro, Zaharieva, Irina, Bohringer, Stefan, Hiller, Monika, Chaouch, Amina, Roos, Andreas, Scotton, Chiara, Claustres, Mireille, Bello, Luca, McDonald, Craig M, Hoffman, Eric P, Koeks, Zaida, Eka Suchiman, H, Cirak, Sebahattin, Scoto, Mariacristina, Reza, Mojgan, 't Hoen, Peter A C, Niks, Erik H, Tuffery-Giraud, Sylvie, Lochmüller, Hanns, Ferlini, Alessandra, Muntoni, Francesco, Aartsma-Rus, Annemieke
Published in European journal of human genetics : EJHG (01.06.2020)
Published in European journal of human genetics : EJHG (01.06.2020)
Get full text
Journal Article
Epigenetic variation during the adult lifespan: cross‐sectional and longitudinal data on monozygotic twin pairs
Talens, Rudolf P., Christensen, Kaare, Putter, Hein, Willemsen, Gonneke, Christiansen, Lene, Kremer, Dennis, Suchiman, H. Eka D., Slagboom, P. Eline, Boomsma, Dorret I., Heijmans, Bastiaan T.
Published in Aging cell (01.08.2012)
Published in Aging cell (01.08.2012)
Get full text
Journal Article
Early gestation as the critical time-window for changes in the prenatal environment to affect the adult human blood methylome
Tobi, Elmar W, Slieker, Roderick C, Stein, Aryeh D, Suchiman, H Eka D, Slagboom, P Eline, van Zwet, Erik W, Heijmans, Bastiaan T, Lumey, L H
Published in International journal of epidemiology (01.08.2015)
Published in International journal of epidemiology (01.08.2015)
Get full text
Journal Article
Leukocyte telomere length associates with prospective mortality independent of immune-related parameters and known genetic markers
DEELEN, Joris, BEEKMAN, Marian, UITTERLINDEN, André G, HOFMAN, Albert, DE CRAEN, Anton J. M, METSPALU, Andres, PEDERSEN, Nancy L, VAN DUIJN, Cornelia M, WOUTER JUKEMA, J, HOUWING-DUISTERMAAT, Jeanine J, SAMANI, Nilesh J, SLAGBOOM, P. Eline, CODD, Veryan, TROMPET, Stella, BROER, Linda, HÄGG, Sara, FISCHER, Krista, THIJSSEN, Peter E, SUCHIMAN, H. Eka D, POSTMUS, Iris
Published in International journal of epidemiology (01.06.2014)
Published in International journal of epidemiology (01.06.2014)
Get full text
Journal Article
Elucidating Epigenetic Regulation by Identifying Functional cis‐Acting Long Noncoding RNAs and Their Targets in Osteoarthritic Articular Cartilage
Hoolwerff, Marcella, Metselaar, Paula I., Tuerlings, Margo, Suchiman, H. Eka D., Lakenberg, Nico, Ramos, Yolande F.M., Cats, Davy, Nelissen, Rob G.H.H., Broekhuis, Demiën, Mei, Hailiang, Almeida, Rodrigo Coutinho, Meulenbelt, Ingrid
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.11.2020)
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.11.2020)
Get full text
Journal Article
Systemic Age-Associated DNA Hypermethylation of ELOVL2 Gene: In Vivo and In Vitro Evidences of a Cell Replication Process
Bacalini, Maria Giulia, Deelen, Joris, Pirazzini, Chiara, De Cecco, Marco, Giuliani, Cristina, Lanzarini, Catia, Ravaioli, Francesco, Marasco, Elena, van Heemst, Diana, Suchiman, H Eka D, Slieker, Roderick, Giampieri, Enrico, Recchioni, Rina, Marcheselli, Fiorella, Salvioli, Stefano, Vitale, Giovanni, Olivieri, Fabiola, Spijkerman, Annemieke M W, Dollé, Martijn E T, Sedivy, John M, Castellani, Gastone, Franceschi, Claudio, Slagboom, Pieternella E, Garagnani, Paolo
Published in The journals of gerontology. Series A, Biological sciences and medical sciences (01.08.2017)
Published in The journals of gerontology. Series A, Biological sciences and medical sciences (01.08.2017)
Get more information
Journal Article
RNA Sequencing Reveals Interacting Key Determinants of Osteoarthritis Acting in Subchondral Bone and Articular Cartilage: Identification of IL11 and CHADL as Attractive Treatment Targets
Tuerlings, Margo, Hoolwerff, Marcella, Houtman, Evelyn, Suchiman, Eka H. E. D., Lakenberg, Nico, Mei, Hailiang, Linden, Enrike H. M. J., Nelissen, Rob R. G. H. H., Ramos, Yolande Y. F. M., Coutinho de Almeida, Rodrigo, Meulenbelt, Ingrid
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.05.2021)
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.05.2021)
Get full text
Journal Article
Identification and systematic annotation of tissue-specific differentially methylated regions using the Illumina 450k array
Slieker, Roderick C, Bos, Steffan D, Goeman, Jelle J, Bovée, Judith Vmg, Talens, Rudolf P, van der Breggen, Ruud, Suchiman, H Eka D, Lameijer, Eric-Wubbo, Putter, Hein, van den Akker, Erik B, Zhang, Yanju, Jukema, J Wouter, Slagboom, P Eline, Meulenbelt, Ingrid, Heijmans, Bastiaan T
Published in Epigenetics & chromatin (06.08.2013)
Published in Epigenetics & chromatin (06.08.2013)
Get full text
Journal Article
The Adult Netherlands Twin Register: Twenty-Five Years of Survey and Biological Data Collection
Willemsen, Gonneke, Vink, Jacqueline M., Abdellaoui, Abdel, den Braber, Anouk, van Beek, Jenny H. D. A., Draisma, Harmen H. M., van Dongen, Jenny, van ‘t Ent, Dennis, Geels, Lot M., van Lien, Rene, Ligthart, Lannie, Kattenberg, Mathijs, Mbarek, Hamdi, de Moor, Marleen H. M., Neijts, Melanie, Pool, Rene, Stroo, Natascha, Kluft, Cornelis, Suchiman, H. Eka D., Slagboom, P. Eline, de Geus, Eco J. C., Boomsma, Dorret I.
Published in Twin research and human genetics (01.02.2013)
Published in Twin research and human genetics (01.02.2013)
Get full text
Journal Article
Author Correction: Heritability estimates for 361 blood metabolites across 40 genome-wide association studies
Hagenbeek, Fiona A., Pool, René, van Dongen, Jenny, Draisma, H. M., Jan Hottenga, Jouke, Willemsen, Gonneke, Abdellaoui, Abdel, Fedko, Iryna O., den Braber, Anouk, Visser, Pieter Jelle, de Geus, Eco J. C. N., Willems van Dijk, Ko, Verhoeven, Aswin, Suchiman, H. Eka, Beekman, Marian, Slagboom, P. Eline, van Duijn, Cornelia M., Harms, Amy C., Hankemeier, Thomas, Bartels, Meike, Nivard, Michel G., Boomsma, Dorret I.
Published in Nature communications (31.03.2020)
Published in Nature communications (31.03.2020)
Get full text
Journal Article
Design, measurement and processing of region-specific DNA methylation assays: the mass spectrometry-based method EpiTYPER
Suchiman, H Eka D, Slieker, Roderick C, Kremer, Dennis, Slagboom, P Eline, Heijmans, Bastiaan T, Tobi, Elmar W
Published in Frontiers in genetics (17.09.2015)
Published in Frontiers in genetics (17.09.2015)
Get full text
Journal Article
Genome-wide association study (GWAS)-identified disease risk alleles do not compromise human longevity
Beekman, Marian, Nederstigt, Christa, Suchiman, H. Eka D., Kremer, Dennis, van der Breggen, Ruud, Lakenberg, Nico, Alemayehu, Wendimagegn Ghidey, de Craen, Anton J. M., Westendorp, Rudi G. J., Boomsma, Dorret I., de Geus, Eco J. C., Houwing-Duistermaat, Jeanine J., Heijmans, Bastiaan T., Slagboom, P. Eline, Cantor, Charles R.
Published in Proceedings of the National Academy of Sciences - PNAS (19.10.2010)
Published in Proceedings of the National Academy of Sciences - PNAS (19.10.2010)
Get full text
Journal Article
Repeat UVA exposure of human skin fibroblasts induces both a transitionary and recovery DNA methylation response
Tilburg, Julia, Slieker, Roderick C, Suchiman, H Eka D, Heath, Alan, Heemst, Diana van, Slagboom, P Eline, de Gruijl, Frank R, Gunn, David A, Heijmans, Bastiaan T
Published in Epigenomics (01.04.2020)
Published in Epigenomics (01.04.2020)
Get full text
Journal Article
Transcriptional Associations of Osteoarthritis‐Mediated Loss of Epigenetic Control in Articular Cartilage
den Hollander, Wouter, Ramos, Yolande F. M., Bomer, Nils, Elzinga, Stefan, van der Breggen, Ruud, Lakenberg, Nico, de Dijcker, Wesley J., Suchiman, H. Eka D., Duijnisveld, Bouke J., Houwing‐Duistermaat, Jeanine J., Slagboom, P. Eline, Bos, Steffan D., Nelissen, Rob G. H. H., Meulenbelt, Ingrid
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.05.2015)
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.05.2015)
Get full text
Journal Article