Variations of Subunit ε of the Mycobacterium tuberculosis F1Fo ATP Synthase and a Novel Model for Mechanism of Action of the Tuberculosis Drug TMC207
BIUKOVIC, Goran, BASAK, Sandip, SUBRAMANIAN MANIMEKALAI, Malathy Sony, RISHIKESAN, Sankaranarayanan, ROESSLE, Manfred, DICK, Thomas, RAO, Srinivasa P. S, HUNKE, Cornelia, GRÜBER, Gerhard
Published in Antimicrobial Agents and Chemotherapy (01.01.2013)
Published in Antimicrobial Agents and Chemotherapy (01.01.2013)
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Journal Article
AhpC of the mycobacterial antioxidant defense system and its interaction with its reducing partner Thioredoxin-C
Wong, Chui Fann, Shin, Joon, Subramanian Manimekalai, Malathy Sony, Saw, Wuan Geok, Yin, Zhan, Bhushan, Shashi, Kumar, Arvind, Ragunathan, Priya, Grüber, Gerhard
Published in Scientific reports (11.07.2017)
Published in Scientific reports (11.07.2017)
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Journal Article
ATP synthases from archaea: The beauty of a molecular motor
Grüber, Gerhard, Manimekalai, Malathy Sony Subramanian, Mayer, Florian, Müller, Volker
Published in Biochimica et biophysica acta (01.06.2014)
Published in Biochimica et biophysica acta (01.06.2014)
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Journal Article
Structural features of Zika virus non-structural proteins 3 and -5 and its individual domains in solution as well as insights into NS3 inhibition
Saw, Wuan Geok, Pan, Ankita, Subramanian Manimekalai, Malathy Sony, Grüber, Gerhard
Published in Antiviral research (01.05.2017)
Published in Antiviral research (01.05.2017)
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Journal Article
The uniqueness of subunit α of mycobacterial F-ATP synthases: An evolutionary variant for niche adaptation
Ragunathan, Priya, Sielaff, Hendrik, Sundararaman, Lavanya, Biuković, Goran, Subramanian Manimekalai, Malathy Sony, Singh, Dhirendra, Kundu, Subhashri, Wohland, Thorsten, Frasch, Wayne, Dick, Thomas, Grüber, Gerhard
Published in The Journal of biological chemistry (07.07.2017)
Published in The Journal of biological chemistry (07.07.2017)
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Journal Article
Atomic structure of, and valine binding to the regulatory ACT domain of the Mycobacterium tuberculosis Rel protein
Shin, Joon, Singal, Bharti, Sony Subramanian Manimekalai, Malathy, Wei Chen, Ming, Ragunathan, Priya, Grüber, Gerhard
Published in The FEBS journal (01.04.2021)
Published in The FEBS journal (01.04.2021)
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Journal Article
Mycobacterium tuberculosis PanD Structure–Function Analysis and Identification of a Potent Pyrazinoic Acid-Derived Enzyme Inhibitor
Ragunathan, Priya, Cole, Malcolm, Latka, Chitra, Aragaw, Wassihun Wedajo, Hegde, Pooja, Shin, Joon, Subramanian Manimekalai, Malathy Sony, Rishikesan, Sankaranarayanan, Aldrich, Courtney C, Dick, Thomas, Grüber, Gerhard
Published in ACS chemical biology (18.06.2021)
Published in ACS chemical biology (18.06.2021)
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Journal Article
Structure and flexibility of non-structural proteins 3 and -5 of Dengue- and Zika viruses in solution
Saw, Wuan Geok, Pan, Ankita, Subramanian Manimekalai, Malathy Sony, Grüber, Ardina, Grüber, Gerhard
Published in Progress in biophysics and molecular biology (01.05.2019)
Published in Progress in biophysics and molecular biology (01.05.2019)
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Journal Article
Identification of the critical linker residues conferring differences in the compactness of NS5 from Dengue virus serotype 4 and NS5 from Dengue virus serotypes 1-3
Subramanian Manimekalai, Malathy Sony, Saw, Wuan Geok, Pan, Ankita, Grüber, Ardina, Grüber, Gerhard
Published in Acta crystallographica. Section D, Structural biology (01.06.2016)
Published in Acta crystallographica. Section D, Structural biology (01.06.2016)
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Journal Article
Structural features of NS3 of Dengue virus serotypes 2 and 4 in solution and insight into RNA binding and the inhibitory role of quercetin
Pan, Ankita, Saw, Wuan Geok, Subramanian Manimekalai, Malathy Sony, Grüber, Ardina, Joon, Shin, Matsui, Tsutomu, Weiss, Thomas M, Grüber, Gerhard
Published in Acta crystallographica. Section D, Biological crystallography. (01.05.2017)
Published in Acta crystallographica. Section D, Biological crystallography. (01.05.2017)
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Journal Article
Structure, mechanism and ensemble formation of the alkylhydroperoxide reductase subunits AhpC and AhpF from Escherichia coli
Dip, Phat Vinh, Kamariah, Neelagandan, Subramanian Manimekalai, Malathy Sony, Nartey, Wilson, Balakrishna, Asha Manikkoth, Eisenhaber, Frank, Eisenhaber, Birgit, Grüber, Gerhard
Published in Acta crystallographica. Section D, Biological crystallography. (01.11.2014)
Published in Acta crystallographica. Section D, Biological crystallography. (01.11.2014)
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Journal Article
Nucleotide Binding States of Subunit A of the A-ATP Synthase and the Implication of P-Loop Switch in Evolution
Kumar, Anil, Manimekalai, Malathy Sony Subramanian, Balakrishna, Asha Manikkoth, Jeyakanthan, Jeyaraman, Grüber, Gerhard
Published in Journal of molecular biology (19.02.2010)
Published in Journal of molecular biology (19.02.2010)
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Journal Article
Crystal and solution structure of the C-terminal part of the Methanocaldococcus jannaschii A₁AO ATP synthase subunit E revealed by X-ray diffraction and small-angle X-ray scattering
Balakrishna, Asha Manikkoth, Manimekalai, Malathy Sony Subramanian, Hunke, Cornelia, Gayen, Shovanlal, Rössle, Manfred, Jeyakanthan, Jeyaraman, Grüber, Gerhard
Published in Journal of bioenergetics and biomembranes (01.08.2010)
Published in Journal of bioenergetics and biomembranes (01.08.2010)
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Journal Article
Crystal Structure of Subunits D and F in Complex Gives Insight into Energy Transmission of the Eukaryotic V-ATPase from Saccharomyces cerevisiae
Balakrishna, Asha Manikkoth, Basak, Sandip, Manimekalai, Malathy Sony Subramanian, Grüber, Gerhard
Published in The Journal of biological chemistry (06.02.2015)
Published in The Journal of biological chemistry (06.02.2015)
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Journal Article
Crystallographic and solution structure of the N‐terminal domain of the Rel protein from Mycobacterium tuberculosis
Singal, Bharti, Balakrishna, Asha Manikkoth, Nartey, Wilson, Manimekalai, Malathy Sony Subramanian, Jeyakanthan, Jeyaraman, Grüber, Gerhard
Published in FEBS letters (01.08.2017)
Published in FEBS letters (01.08.2017)
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Journal Article
Redox chemistry of Mycobacterium tuberculosis alkylhydroperoxide reductase E (AhpE): Structural and mechanistic insight into a mycoredoxin-1 independent reductive pathway of AhpE via mycothiol
Kumar, Arvind, Balakrishna, Asha Manikkoth, Nartey, Wilson, Manimekalai, Malathy Sony Subramanian, Grüber, Gerhard
Published in Free radical biology & medicine (01.08.2016)
Published in Free radical biology & medicine (01.08.2016)
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Journal Article