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Ferroptotic cell death triggered by conjugated linolenic acids is mediated by ACSL1
Beatty, Alexander, Singh, Tanu, Tyurina, Yulia Y., Tyurin, Vladimir A., Samovich, Svetlana, Nicolas, Emmanuelle, Maslar, Kristen, Zhou, Yan, Cai, Kathy Q., Tan, Yinfei, Doll, Sebastian, Conrad, Marcus, Subramanian, Aravind, Bayır, Hülya, Kagan, Valerian E., Rennefahrt, Ulrike, Peterson, Jeffrey R.
Published in Nature communications (14.04.2021)
Published in Nature communications (14.04.2021)
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Molecular signatures database (MSigDB) 3.0
Liberzon, Arthur, Subramanian, Aravind, Pinchback, Reid, Thorvaldsdóttir, Helga, Tamayo, Pablo, Mesirov, Jill P.
Published in Bioinformatics (Oxford, England) (15.06.2011)
Published in Bioinformatics (Oxford, England) (15.06.2011)
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The Drug Repurposing Hub: a next-generation drug library and information resource
Corsello, Steven M, Bittker, Joshua A, Liu, Zihan, Gould, Joshua, McCarren, Patrick, Hirschman, Jodi E, Johnston, Stephen E, Vrcic, Anita, Wong, Bang, Khan, Mariya, Asiedu, Jacob, Narayan, Rajiv, Mader, Christopher C, Subramanian, Aravind, Golub, Todd R
Published in Nature medicine (07.04.2017)
Published in Nature medicine (07.04.2017)
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GSEA-P: a desktop application for Gene Set Enrichment Analysis
Subramanian, Aravind, Kuehn, Heidi, Gould, Joshua, Tamayo, Pablo, Mesirov, Jill P.
Published in Bioinformatics (01.12.2007)
Published in Bioinformatics (01.12.2007)
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Evaluation of RNAi and CRISPR technologies by large-scale gene expression profiling in the Connectivity Map
Smith, Ian, Greenside, Peyton G., Natoli, Ted, Lahr, David L., Wadden, David, Tirosh, Itay, Narayan, Rajiv, Root, David E., Golub, Todd R., Subramanian, Aravind, Doench, John G.
Published in PLoS biology (30.11.2017)
Published in PLoS biology (30.11.2017)
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Molecular Liver Cancer Prevention in Cirrhosis by Organ Transcriptome Analysis and Lysophosphatidic Acid Pathway Inhibition
Nakagawa, Shigeki, Wei, Lan, Song, Won Min, Higashi, Takaaki, Ghoshal, Sarani, Kim, Rosa S., Bian, C. Billie, Yamada, Suguru, Sun, Xiaochen, Venkatesh, Anu, Goossens, Nicolas, Bain, Gretchen, Lauwers, Gregory Y., Koh, Anna P., El-Abtah, Mohamed, Ahmad, Noor B., Hoshida, Hiroki, Erstad, Derek J., Gunasekaran, Ganesh, Lee, Youngmin, Yu, Ming-Lung, Chuang, Wan-Long, Dai, Chia-Yen, Kobayashi, Masahiro, Kumada, Hiromitsu, Beppu, Toru, Baba, Hideo, Mahajan, Milind, Nair, Venugopalan D., Lanuti, Michael, Villanueva, Augusto, Sangiovanni, Angelo, Iavarone, Massimo, Colombo, Massimo, Llovet, Josep M., Subramanian, Aravind, Tager, Andrew M., Friedman, Scott L., Baumert, Thomas F., Schwarz, Myron E., Chung, Raymond T., Tanabe, Kenneth K., Zhang, Bin, Fuchs, Bryan C., Hoshida, Yujin
Published in Cancer cell (12.12.2016)
Published in Cancer cell (12.12.2016)
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Discovering the anticancer potential of non-oncology drugs by systematic viability profiling
Corsello, Steven M, Nagari, Rohith T, Spangler, Ryan D, Rossen, Jordan, Kocak, Mustafa, Bryan, Jordan G, Humeidi, Ranad, Peck, David, Wu, Xiaoyun, Tang, Andrew A, Wang, Vickie M, Bender, Samantha A, Lemire, Evan, Narayan, Rajiv, Montgomery, Philip, Ben-David, Uri, Garvie, Colin W, Chen, Yejia, Rees, Matthew G, Lyons, Nicholas J, McFarland, James M, Wong, Bang T, Wang, Li, Dumont, Nancy, O’Hearn, Patrick J, Stefan, Eric, Doench, John G, Harrington, Caitlin N, Greulich, Heidi, Meyerson, Matthew, Vazquez, Francisca, Subramanian, Aravind, Roth, Jennifer A, Bittker, Joshua A, Boehm, Jesse S, Mader, Christopher C, Tsherniak, Aviad, Golub, Todd R
Published in Nature cancer (01.02.2020)
Published in Nature cancer (01.02.2020)
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LINCS Canvas Browser: interactive web app to query, browse and interrogate LINCS L1000 gene expression signatures
Duan, Qiaonan, Flynn, Corey, Niepel, Mario, Hafner, Marc, Muhlich, Jeremy L., Fernandez, Nicolas F., Rouillard, Andrew D., Tan, Christopher M., Chen, Edward Y., Golub, Todd R., Sorger, Peter K., Subramanian, Aravind, Ma'ayan, Avi
Published in Nucleic acids research (01.07.2014)
Published in Nucleic acids research (01.07.2014)
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High-throughput Phenotyping of Lung Cancer Somatic Mutations
Berger, Alice H., Brooks, Angela N., Wu, Xiaoyun, Shrestha, Yashaswi, Chouinard, Candace, Piccioni, Federica, Bagul, Mukta, Kamburov, Atanas, Imielinski, Marcin, Hogstrom, Larson, Zhu, Cong, Yang, Xiaoping, Pantel, Sasha, Sakai, Ryo, Watson, Jacqueline, Kaplan, Nathan, Campbell, Joshua D., Singh, Shantanu, Root, David E., Narayan, Rajiv, Natoli, Ted, Lahr, David L., Tirosh, Itay, Tamayo, Pablo, Getz, Gad, Wong, Bang, Doench, John, Subramanian, Aravind, Golub, Todd R., Meyerson, Matthew, Boehm, Jesse S.
Published in Cancer cell (08.08.2016)
Published in Cancer cell (08.08.2016)
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Tight Coordination of Protein Translation and HSF1 Activation Supports the Anabolic Malignant State
Santagata, Sandro, Mendillo, Marc L., Tang, Yun-chi, Subramanian, Aravind, Perley, Casey C., Roche, Stéphane P., Wong, Bang, Narayan, Rajiv, Kwon, Hyoungtae, Koeva, Martina, Amon, Angelika, Golub, Todd R., Porco, John A., Whitesell, Luke, Lindquist, Susan
Published in Science (American Association for the Advancement of Science) (19.07.2013)
Published in Science (American Association for the Advancement of Science) (19.07.2013)
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On the Czochralski growth of SixGe1−x crystals as substrates for strained Ge quantum well heterostructures
Subramanian, Aravind N., Richter, Carsten, Gybin, Alexander, Kabukcuoglu, Merve P., Hamann, Elias, Zuber, Marcus, Oezkent, Maximilian, Guguschev, Christo, Juda, Uta, Schroeder, Thomas, Abrosimov, Nikolay V., Sumathi, R. Radhakrishnan, Gradwohl, Kevin-P.
Published in Journal of applied physics (14.02.2025)
Published in Journal of applied physics (14.02.2025)
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Common and cell-type specific responses to anti-cancer drugs revealed by high throughput transcript profiling
Niepel, Mario, Hafner, Marc, Duan, Qiaonan, Wang, Zichen, Paull, Evan O., Chung, Mirra, Lu, Xiaodong, Stuart, Joshua M., Golub, Todd R., Subramanian, Aravind, Ma’ayan, Avi, Sorger, Peter K.
Published in Nature communications (30.10.2017)
Published in Nature communications (30.10.2017)
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Selective killing of K-ras mutant cancer cells by small molecule inducers of oxidative stress
Shaw, Alice T, Winslow, Monte M, Magendantz, Margaret, Ouyang, Chensi, Dowdle, James, Subramanian, Aravind, Lewis, Timothy A, Maglathin, Rebecca L, Tolliday, Nicola, Jacks, Tyler
Published in Proceedings of the National Academy of Sciences - PNAS (24.05.2011)
Published in Proceedings of the National Academy of Sciences - PNAS (24.05.2011)
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Densely Interconnected Transcriptional Circuits Control Cell States in Human Hematopoiesis
Novershtern, Noa, Subramanian, Aravind, Lawton, Lee N., Mak, Raymond H., Haining, W. Nicholas, McConkey, Marie E., Habib, Naomi, Yosef, Nir, Chang, Cindy Y., Shay, Tal, Frampton, Garrett M., Drake, Adam C.B., Leskov, Ilya, Nilsson, Bjorn, Preffer, Fred, Dombkowski, David, Evans, John W., Liefeld, Ted, Smutko, John S., Chen, Jianzhu, Friedman, Nir, Young, Richard A., Golub, Todd R., Regev, Aviv, Ebert, Benjamin L.
Published in Cell (21.01.2011)
Published in Cell (21.01.2011)
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Drug and disease signature integration identifies synergistic combinations in glioblastoma
Stathias, Vasileios, Jermakowicz, Anna M., Maloof, Marie E., Forlin, Michele, Walters, Winston, Suter, Robert K., Durante, Michael A., Williams, Sion L., Harbour, J. William, Volmar, Claude-Henry, Lyons, Nicholas J., Wahlestedt, Claes, Graham, Regina M., Ivan, Michael E., Komotar, Ricardo J., Sarkaria, Jann N., Subramanian, Aravind, Golub, Todd R., Schürer, Stephan C., Ayad, Nagi G.
Published in Nature communications (14.12.2018)
Published in Nature communications (14.12.2018)
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SNP-based pathway enrichment analysis for genome-wide association studies
Weng, Lingjie, Macciardi, Fabio, Subramanian, Aravind, Guffanti, Guia, Potkin, Steven G, Yu, Zhaoxia, Xie, Xiaohui
Published in BMC bioinformatics (15.04.2011)
Published in BMC bioinformatics (15.04.2011)
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Gene Set Enrichment Analysis: A Knowledge-Based Approach for Interpreting Genome-Wide Expression Profiles
Subramanian, Aravind, Tamayo, Pablo, Mootha, Vamsi K., Mukherjee, Sayan, Benjamin L. Ebert, Michael A. Gillette, Amanda Paulovich, Pomeroy, Scott L., Golub, Todd R., Lander, Eric S., Mesirov, Jill P.
Published in Proceedings of the National Academy of Sciences - PNAS (25.10.2005)
Published in Proceedings of the National Academy of Sciences - PNAS (25.10.2005)
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