HPMA copolymer-doxorubicin conjugates: The effects of molecular weight and architecture on biodistribution and in vivo activity
Etrych, Tomáš, Šubr, Vladimír, Strohalm, Jiří, Šírová, Milada, Říhová, Blanka, Ulbrich, Karel
Published in Journal of controlled release (28.12.2012)
Published in Journal of controlled release (28.12.2012)
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Polymer conjugates of doxorubicin bound through an amide and hydrazone bond: Impact of the carrier structure onto synergistic action in the treatment of solid tumours
Etrych, Tomáš, Šubr, Vladimír, Laga, Richard, Říhová, Blanka, Ulbrich, Karel
Published in European journal of pharmaceutical sciences (16.07.2014)
Published in European journal of pharmaceutical sciences (16.07.2014)
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Journal Article
N-(2-Hydroxypropyl)methacrylamide-based polymer conjugates with pH-controlled activation of doxorubicin for cell-specific or passive tumour targeting. Synthesis by RAFT polymerisation and physicochemical characterisation
Chytil, Petr, Etrych, Tomáš, Kříž, Jaroslav, Šubr, Vladimír, Ulbrich, Karel
Published in European journal of pharmaceutical sciences (20.11.2010)
Published in European journal of pharmaceutical sciences (20.11.2010)
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Journal Article
N‑(2-Hydroxypropyl)methacrylamide-Based Linear, Diblock, and Starlike Polymer Drug Carriers: Advanced Process for Their Simple Production
Koziolová, Eva, Kostka, Libor, Kotrchová, Lenka, Šubr, Vladimír, Konefal, Rafal, Nottelet, Benjamin, Etrych, Tomáš
Published in Biomacromolecules (08.10.2018)
Published in Biomacromolecules (08.10.2018)
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The development of a high-affinity conformation-sensitive antibody mimetic using a biocompatible copolymer carrier (iBody)
Blažková, Kristyna, Beranová, Jana, Hradilek, Martin, Kostka, Libor, Šubr, Vladimír, Etrych, Tomáš, Šácha, Pavel, Konvalinka, Jan
Published in The Journal of biological chemistry (01.11.2021)
Published in The Journal of biological chemistry (01.11.2021)
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Journal Article
Highly Effective Synthetic Polymer-Based Blockers of Non-Specific Interactions in Immunochemical Analyses
Šubr, Vladimír, Kostka, Libor, Plicka, Jan, Sedláček, Ondřej, Etrych, Tomáš
Published in Polymers (01.03.2024)
Published in Polymers (01.03.2024)
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Journal Article
Simultaneous Delivery of Doxorubicin and Protease Inhibitor Derivative to Solid Tumors via Star-Shaped Polymer Nanomedicines Overcomes P‑gp- and STAT3-Mediated Chemoresistance
Kostka, Libor, Sivák, Ladislav, Šubr, Vladimír, Kovářová, Jiřina, Šírová, Milada, Říhová, Blanka, Sedlacek, Radislav, Etrych, Tomáš, Kovář, Marek
Published in Biomacromolecules (13.06.2022)
Published in Biomacromolecules (13.06.2022)
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Unraveling the role of Intralipid in suppressing off-target delivery and augmenting the therapeutic effects of anticancer nanomedicines
Islam, Rayhanul, Gao, Shanghui, Islam, Waliul, Šubr, Vladimír, Zhou, Jian-Rong, Yokomizo, Kazumi, Etrych, Tomáš, Maeda, Hiroshi, Fang, Jun
Published in Acta biomaterialia (01.05.2021)
Published in Acta biomaterialia (01.05.2021)
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Journal Article
N-(2-hydroxypropyl)methacrylamide polymer conjugated pyropheophorbide-a, a promising tumor-targeted theranostic probe for photodynamic therapy and imaging
Fang, Jun, Šubr, Vladimír, Islam, Waliul, Hackbarth, Steffen, Islam, Rayhanul, Etrych, Tomáš, Ulbrich, Karel, Maeda, Hiroshi
Published in European journal of pharmaceutics and biopharmaceutics (01.09.2018)
Published in European journal of pharmaceutics and biopharmaceutics (01.09.2018)
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Journal Article
Traceless bioresponsive shielding of adenovirus hexon with HPMA copolymers maintains transduction capacity in vitro and in vivo
Prill, Jan-Michael, Subr, Vladimír, Pasquarelli, Noemi, Engler, Tatjana, Hoffmeister, Andrea, Kochanek, Stefan, Ulbrich, Karel, Kreppel, Florian
Published in PloS one (27.01.2014)
Published in PloS one (27.01.2014)
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Journal Article
HPMA-based star polymer biomaterials with tuneable structure and biodegradability tailored for advanced drug delivery to solid tumours
Kostka, Libor, Kotrchová, Lenka, Šubr, Vladimír, Libánská, Alena, Ferreira, Carolina A., Malátová, Iva, Lee, Hye Jin, Barnhart, Todd E., Engle, Jonathan W., Cai, Weibo, Šírová, Milada, Etrych, Tomáš
Published in Biomaterials (01.03.2020)
Published in Biomaterials (01.03.2020)
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Journal Article
The role of the biotin linker in polymer antibody mimetics, iBodies, in biochemical assays
Šubr, Vladimír, Ormsby, Tereza, Šácha, Pavel, Konvalinka, Jan, Etrych, Tomáš, Kostka, Libor
Published in Polymer chemistry (26.10.2021)
Published in Polymer chemistry (26.10.2021)
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Journal Article
HPMA copolymer conjugated 5-aminolevulinic acid exhibits superior efficacy for photodynamic therapy with tumor-responsive and targeting properties
Islam, Rayhanul, Kotalík, Kevin, Šubr, Vladimír, Gao, Shanghui, Zhou, Jian-Rong, Yokomizo, Kazumi, Etrych, Tomáš, Fang, Jun
Published in Nanomedicine (01.02.2023)
Published in Nanomedicine (01.02.2023)
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Journal Article
Inhibitor-Decorated Polymer Conjugates Targeting Fibroblast Activation Protein
Dvořáková, Petra, Bušek, Petr, Knedlík, Tomáš, Schimer, Jiří, Etrych, Tomáš, Kostka, Libor, Stollinová Šromová, Lucie, Šubr, Vladimír, Šácha, Pavel, Šedo, Aleksi, Konvalinka, Jan
Published in Journal of medicinal chemistry (26.10.2017)
Published in Journal of medicinal chemistry (26.10.2017)
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Journal Article
iBodies: Modular Synthetic Antibody Mimetics Based on Hydrophilic Polymers Decorated with Functional Moieties
Šácha, Pavel, Knedlík, Tomáš, Schimer, Jiří, Tykvart, Jan, Parolek, Jan, Navrátil, Václav, Dvořáková, Petra, Sedlák, František, Ulbrich, Karel, Strohalm, Jiří, Majer, Pavel, Šubr, Vladimír, Konvalinka, Jan
Published in Angewandte Chemie International Edition (12.02.2016)
Published in Angewandte Chemie International Edition (12.02.2016)
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Journal Article
Enhanced Tumor Uptake and Penetration of Virotherapy Using Polymer Stealthing and Focused Ultrasound
CARLISLE, Robert, CHOI, James, BAZAN-PEREGRINO, Miriam, LAGA, Richard, SUBR, Vladimir, KOSTKA, Libor, ULBRICH, Karel, COUSSIOS, Constantin-C, SEYMOUR, Leonard W
Published in JNCI : Journal of the National Cancer Institute (20.11.2013)
Published in JNCI : Journal of the National Cancer Institute (20.11.2013)
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Journal Article
Tumor-specific targeting of polymer drug delivery systems with recombinant proteins bound via tris(nitrilotriacetic acid)
Pechar, Michal, Král, Vlastimil, Kracíková, Lucie, Androvič, Ladislav, Hrdá, Eliška, Pola, Robert, Pytlíková, Sára, Studenovský, Martin, Kostka, Libor, Šubr, Vladimír, Etrych, Tomáš, Kočková, Olga, Marianne Ferreira Mendes, Jessica, Fábry, Milan, Laga, Richard
Published in International journal of pharmaceutics (15.12.2023)
Published in International journal of pharmaceutics (15.12.2023)
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