Constitutive activation of RANK disrupts mammary cell fate leading to tumorigenesis
Pellegrini, Pasquale, Cordero, Alex, Gallego, Marta Ines, Dougall, William C., Purificación, Muñoz, Pujana, Miguel Angel, Gonzalez‐Suarez, Eva
Published in Stem cells (Dayton, Ohio) (01.09.2013)
Published in Stem cells (Dayton, Ohio) (01.09.2013)
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RANK is a poor prognosis marker and a therapeutic target in ER‐negative postmenopausal breast cancer
Ciscar, Marina, Trinidad, Eva M, Perez‐Chacon, Gema, Alsaleem, Mansour, Jimenez, Maria, Jimenez‐Santos, Maria J, Perez‐Montoyo, Hector, Sanz‐Moreno, Adrian, Vethencourt, Andrea, Toss, Michael, Petit, Anna, Soler‐Monso, Maria T, Lopez, Victor, Gomez‐Miragaya, Jorge, Gomez‐Aleza, Clara, Dobrolecki, Lacey E, Lewis, Michael T, Bruna, Alejandra, Mouron, Silvana, Quintela‐Fandino, Miguel, Al‐Shahrour, Fatima, Martinez‐Aranda, Antonio, Sierra, Angels, Green, Andrew R, Rakha, Emad, Gonzalez‐Suarez, Eva
Published in EMBO molecular medicine (11.04.2023)
Published in EMBO molecular medicine (11.04.2023)
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Journal Article
Linkage of DNA Methylation Quantitative Trait Loci to Human Cancer Risk
Heyn, Holger, Sayols, Sergi, Moutinho, Catia, Vidal, Enrique, Sanchez-Mut, Jose V., Stefansson, Olafur A., Nadal, Ernest, Moran, Sebastian, Eyfjord, Jorunn E., Gonzalez-Suarez, Eva, Pujana, Miguel Angel, Esteller, Manel
Published in Cell reports (Cambridge) (24.04.2014)
Published in Cell reports (Cambridge) (24.04.2014)
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Bromodomain inhibition shows antitumoral activity in mice and human luminal breast cancer
Pérez-Salvia, Montserrat, Simó-Riudalbas, Laia, Llinàs-Arias, Pere, Roa, Laura, Setien, Fernando, Soler, Marta, de Moura, Manuel Castro, Bradner, James E, Gonzalez-Suarez, Eva, Moutinho, Catia, Esteller, Manel
Published in Oncotarget (01.08.2017)
Published in Oncotarget (01.08.2017)
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RANKL/RANK control Brca1 mutation-driven mammary tumors
Sigl, Verena, Owusu-Boaitey, Kwadwo, Joshi, Purna A, Kavirayani, Anoop, Wirnsberger, Gerald, Novatchkova, Maria, Kozieradzki, Ivona, Schramek, Daniel, Edokobi, Nnamdi, Hersl, Jerome, Sampson, Aishia, Odai-Afotey, Ashley, Lazaro, Conxi, Gonzalez-Suarez, Eva, Pujana, Miguel A, CIMBA, for, Heyn, Holger, Vidal, Enrique, Cruickshank, Jennifer, Berman, Hal, Sarao, Renu, Ticevic, Melita, Uribesalgo, Iris, Tortola, Luigi, Rao, Shuan, Tan, Yen, Pfeiler, Georg, Lee, Eva YHP, Bago-Horvath, Zsuzsanna, Kenner, Lukas, Popper, Helmuth, Singer, Christian, Khokha, Rama, Jones, Laundette P, Penninger, Josef M
Published in Cell research (01.07.2016)
Published in Cell research (01.07.2016)
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Journal Article
BRCA1 CpG island hypermethylation predicts sensitivity to poly(adenosine diphosphate)-ribose polymerase inhibitors
Veeck, Jurgen, Ropero, Santiago, Setien, Fernando, Gonzalez-Suarez, Eva, Osorio, Ana, Benitez, Javier, Herman, James G, Esteller, Manel
Published in Journal of clinical oncology (10.10.2010)
Published in Journal of clinical oncology (10.10.2010)
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Journal Article
Cancer cell plasticity defines response to immunotherapy in cutaneous squamous cell carcinoma
Lorenzo-Sanz, Laura, Lopez-Cerda, Marta, da Silva-Diz, Victoria, Artés, Marta H., Llop, Sandra, Penin, Rosa M., Bermejo, Josep Oriol, Gonzalez-Suarez, Eva, Esteller, Manel, Viñals, Francesc, Espinosa, Enrique, Oliva, Marc, Piulats, Josep M., Martin-Liberal, Juan, Muñoz, Purificación
Published in Nature communications (24.06.2024)
Published in Nature communications (24.06.2024)
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Journal Article
RANK signaling increases after anti-HER2 therapy contributing to the emergence of resistance in HER2-positive breast cancer
Sanz-Moreno, Adrián, Palomeras, Sonia, Pedersen, Kim, Morancho, Beatriz, Pascual, Tomas, Galván, Patricia, Benítez, Sandra, Gomez-Miragaya, Jorge, Ciscar, Marina, Jimenez, Maria, Pernas, Sonia, Petit, Anna, Soler-Monsó, María Teresa, Viñas, Gemma, Alsaleem, Mansour, Rakha, Emad A, Green, Andrew R, Santamaria, Patricia G, Mulder, Celine, Lemeer, Simone, Arribas, Joaquin, Prat, Aleix, Puig, Teresa, Gonzalez-Suarez, Eva
Published in Breast cancer research : BCR (30.03.2021)
Published in Breast cancer research : BCR (30.03.2021)
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Journal Article
Co-targeting RANK pathway treats and prevents acquired resistance to CDK4/6 inhibitors in luminal breast cancer
Gomes, Inês, Gallego-Paez, Lina M., Jiménez, Maria, Santamaria, Patricia G., Mansinho, André, Sousa, Rita, Abreu, Catarina, Suárez, Eva González, Costa, Luis, Casimiro, Sandra
Published in Cell reports. Medicine (15.08.2023)
Published in Cell reports. Medicine (15.08.2023)
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Journal Article
European Network of Breast Development and Cancer turned 10 years: a growing family of mammary gland researchers
Koledova, Zuzana, Howard, Beatrice A, Englund, Johanna, Bach, Karsten, Bentires-Alj, Mohammed, Gonzalez-Suarez, Eva
Published in Breast cancer research : BCR (04.09.2018)
Published in Breast cancer research : BCR (04.09.2018)
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Journal Article
Conference Proceeding
RANK Overexpression in Transgenic Mice with Mouse Mammary Tumor Virus Promoter-Controlled RANK Increases Proliferation and Impairs Alveolar Differentiation in the Mammary Epithelia and Disrupts Lumen Formation in Cultured Epithelial Acini
Gonzalez-Suarez, Eva, Branstetter, Daniel, Armstrong, Allison, Dinh, Huyen, Blumberg, Hal, Dougall, William C.
Published in Molecular and Cellular Biology (01.02.2007)
Published in Molecular and Cellular Biology (01.02.2007)
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Journal Article
BTNL2, a Butyrophilin/B7-Like Molecule, Is a Negative Costimulatory Molecule Modulated in Intestinal Inflammation
Arnett, Heather A, Escobar, Sabine S, Gonzalez-Suarez, Eva, Budelsky, Alison L, Steffen, Lori A, Boiani, Norman, Zhang, Ming, Siu, Gerald, Brewer, Avery W, Viney, Joanne L
Published in The Journal of immunology (1950) (01.02.2007)
Published in The Journal of immunology (1950) (01.02.2007)
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Journal Article
RANK Induces Epithelial―Mesenchymal Transition and Stemness in Human Mammary Epithelial Cells and Promotes Tumorigenesis and Metastasis
PALAFOX, Marta, FERRER, Irene, TOMETSKO, Mark, BRANSTETTER, Dan, DOUGALL, William C, GONZALEZ-SUAREZ, Eva, PELLEGRINI, Pasquale, VILA, Sergi, HERNANDEZ-ORTEGA, Sara, URRUTICOECHEA, Ander, CLIMEN, Fina, SOLER, Maria Teresa, MUNOZ, Purificación, VINALS, Francesc
Published in Cancer research (Chicago, Ill.) (01.06.2012)
Published in Cancer research (Chicago, Ill.) (01.06.2012)
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Journal Article
Luminal Rank loss decreases cell fitness leading to basal cell bipotency in parous mammary glands
Rocha, Ana Sofia, Collado-Solé, Alejandro, Graña-Castro, Osvaldo, Redondo-Pedraza, Jaime, Soria-Alcaide, Gonzalo, Cordero, Alex, Santamaría, Patricia G., González-Suárez, Eva
Published in Nature communications (09.10.2023)
Published in Nature communications (09.10.2023)
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Journal Article
Dual fatty acid synthase and HER2 signaling blockade shows marked antitumor activity against breast cancer models resistant to anti-HER2 drugs
Blancafort, Adriana, Giró-Perafita, Ariadna, Oliveras, Glòria, Palomeras, Sònia, Turrado, Carlos, Campuzano, Òscar, Carrión-Salip, Dolors, Massaguer, Anna, Brugada, Ramon, Palafox, Marta, Gómez-Miragaya, Jorge, González-Suárez, Eva, Puig, Teresa
Published in PloS one (24.06.2015)
Published in PloS one (24.06.2015)
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Journal Article
Resistance to Taxanes in Triple-Negative Breast Cancer Associates with the Dynamics of a CD49f+ Tumor-Initiating Population
Gómez-Miragaya, Jorge, Palafox, Marta, Paré, Laia, Yoldi, Guillermo, Ferrer, Irene, Vila, Sergi, Galván, Patricia, Pellegrini, Pasquale, Pérez-Montoyo, Hector, Igea, Ana, Muñoz, Purificación, Esteller, Manel, Nebreda, Angel R., Urruticoechea, Ander, Morilla, Idoia, Pernas, Sonia, Climent, Fina, Soler-Monso, María Teresa, Petit, Ana, Serra, Violeta, Prat, Aleix, González-Suárez, Eva
Published in Stem cell reports (09.05.2017)
Published in Stem cell reports (09.05.2017)
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Journal Article
RANK ligand mediates progestin-induced mammary epithelial proliferation and carcinogenesis
Branstetter, Dan, Pinkas, Jan, Dougall, William C, Erwert, Ryan, Miller, Robert, Jacob, Allison P, Jones, Jon, Gonzalez-Suarez, Eva, Roudier-Meyer, Martine P
Published in Nature (London) (04.11.2010)
Published in Nature (London) (04.11.2010)
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Interrogating open issues in cancer precision medicine with patient-derived xenografts
Byrne, Annette T., Alférez, Denis G., Amant, Frédéric, Annibali, Daniela, Arribas, Joaquín, Biankin, Andrew V., Bruna, Alejandra, Budinská, Eva, Caldas, Carlos, Chang, David K., Clarke, Robert B., Clevers, Hans, Coukos, George, Dangles-Marie, Virginie, Eckhardt, S. Gail, Gonzalez-Suarez, Eva, Hermans, Els, Hidalgo, Manuel, Jarzabek, Monika A., de Jong, Steven, Jonkers, Jos, Kemper, Kristel, Lanfrancone, Luisa, Mælandsmo, Gunhild Mari, Marangoni, Elisabetta, Marine, Jean-Christophe, Medico, Enzo, Norum, Jens Henrik, Palmer, Héctor G., Peeper, Daniel S., Pelicci, Pier Giuseppe, Piris-Gimenez, Alejandro, Roman-Roman, Sergio, Rueda, Oscar M., Seoane, Joan, Serra, Violeta, Soucek, Laura, Vanhecke, Dominique, Villanueva, Alberto, Vinolo, Emilie, Bertotti, Andrea, Trusolino, Livio
Published in Nature reviews. Cancer (01.04.2017)
Published in Nature reviews. Cancer (01.04.2017)
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