NLRP3 inflammasome assembly is regulated by phosphorylation of the pyrin domain
Stutz, Andrea, Kolbe, Carl-Christian, Stahl, Rainer, Horvath, Gabor L, Franklin, Bernardo S, van Ray, Olivia, Brinkschulte, Rebecca, Geyer, Matthias, Meissner, Felix, Latz, Eicke
Published in The Journal of experimental medicine (05.06.2017)
Published in The Journal of experimental medicine (05.06.2017)
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NLRP3 is activated in Alzheimer’s disease and contributes to pathology in APP/PS1 mice
Heneka, Michael T., Kummer, Markus P., Stutz, Andrea, Delekate, Andrea, Schwartz, Stephanie, Vieira-Saecker, Ana, Griep, Angelika, Axt, Daisy, Remus, Anita, Tzeng, Te-Chen, Gelpi, Ellen, Halle, Annett, Korte, Martin, Latz, Eicke, Golenbock, Douglas T.
Published in Nature (London) (31.01.2013)
Published in Nature (London) (31.01.2013)
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Journal Article
Human NACHT, LRR, and PYD domain–containing protein 3 (NLRP3) inflammasome activity is regulated by and potentially targetable through Bruton tyrosine kinase
Liu, Xiao, MSc, Pichulik, Tica, MSc, PhD, Wolz, Olaf-Oliver, MSc, PhD, Dang, Truong-Minh, MSc, PhD, Stutz, Andrea, MSc, Dillen, Carly, MSc, PhD, Delmiro Garcia, Magno, MSc, Kraus, Helene, MD, Dickhöfer, Sabine, MTA, Daiber, Ellen, MSc, Münzenmayer, Lisa, MSc, Wahl, Silke, MSc, PhD, Rieber, Nikolaus, MD, Kümmerle-Deschner, Jasmin, MD, Yazdi, Amir, MD, Franz-Wachtel, Mirita, MSc, PhD, Macek, Boris, MSc, PhD, Radsak, Markus, MD, Vogel, Sebastian, MD, Schulte, Berit, MD, Walz, Juliane Sarah, MD, Hartl, Dominik, MD, PhD, Latz, Eicke, MD, PhD, Stilgenbauer, Stephan, MD, PhD, Grimbacher, Bodo, MD, PhD, Miller, Lloyd, MD, PhD, Brunner, Cornelia, MSc, PhD, Wolz, Christiane, MSc, PhD, Weber, Alexander N.R., MPhil, PhD
Published in Journal of allergy and clinical immunology (01.10.2017)
Published in Journal of allergy and clinical immunology (01.10.2017)
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Journal Article
A small-molecule inhibitor of the NLRP3 inflammasome for the treatment of inflammatory diseases
Coll, Rebecca C, Robertson, Avril A B, Chae, Jae Jin, Higgins, Sarah C, Muñoz-Planillo, Raúl, Inserra, Marco C, Vetter, Irina, Dungan, Lara S, Monks, Brian G, Stutz, Andrea, Croker, Daniel E, Butler, Mark S, Haneklaus, Moritz, Sutton, Caroline E, Núñez, Gabriel, Latz, Eicke, Kastner, Daniel L, Mills, Kingston H G, Masters, Seth L, Schroder, Kate, Cooper, Matthew A, O'Neill, Luke A J
Published in Nature medicine (01.03.2015)
Published in Nature medicine (01.03.2015)
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Journal Article
Activation of the NLRP3 inflammasome by IAV virulence protein PB1-F2 contributes to severe pathophysiology and disease
McAuley, Julie L, Tate, Michelle D, MacKenzie-Kludas, Charley J, Pinar, Anita, Zeng, Weiguang, Stutz, Andrea, Latz, Eicke, Brown, Lorena E, Mansell, Ashley
Published in PLoS pathogens (01.05.2013)
Published in PLoS pathogens (01.05.2013)
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Journal Article
Dual Engagement of the NLRP3 and AIM2 Inflammasomes by Plasmodium-Derived Hemozoin and DNA during Malaria
Kalantari, Parisa, DeOliveira, Rosane B., Chan, Jennie, Corbett, Yolanda, Rathinam, Vijay, Stutz, Andrea, Latz, Eicke, Gazzinelli, Ricardo T., Golenbock, Douglas T., Fitzgerald, Katherine A.
Published in Cell reports (Cambridge) (01.01.2014)
Published in Cell reports (Cambridge) (01.01.2014)
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Journal Article
Inflammasomes: too big to miss
Stutz, Andrea, Golenbock, Douglas T, Latz, Eicke
Published in The Journal of clinical investigation (01.12.2009)
Published in The Journal of clinical investigation (01.12.2009)
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Journal Article
Cutting Edge: NF-κB Activating Pattern Recognition and Cytokine Receptors License NLRP3 Inflammasome Activation by Regulating NLRP3 Expression
Bauernfeind, Franz G., Horvath, Gabor, Stutz, Andrea, Alnemri, Emad S., MacDonald, Kelly, Speert, David, Fernandes-Alnemri, Teresa, Wu, Jianghong, Monks, Brian G., Fitzgerald, Katherine A., Hornung, Veit, Latz, Eicke
Published in The Journal of immunology (1950) (15.07.2009)
Published in The Journal of immunology (1950) (15.07.2009)
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Journal Article
The adaptor ASC has extracellular and 'prionoid' activities that propagate inflammation
Franklin, Bernardo S, Bossaller, Lukas, De Nardo, Dominic, Ratter, Jacqueline M, Stutz, Andrea, Engels, Gudrun, Brenker, Christoph, Nordhoff, Mark, Mirandola, Sandra R, Al-Amoudi, Ashraf, Mangan, Matthew S, Zimmer, Sebastian, Monks, Brian G, Fricke, Martin, Schmidt, Reinhold E, Espevik, Terje, Jones, Bernadette, Jarnicki, Andrew G, Hansbro, Philip M, Busto, Patricia, Marshak-Rothstein, Ann, Hornemann, Simone, Aguzzi, Adriano, Kastenmüller, Wolfgang, Latz, Eicke
Published in Nature immunology (01.08.2014)
Published in Nature immunology (01.08.2014)
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Journal Article
Chemical genetics reveals a kinase-independent role for protein kinase R in pyroptosis
Hett, Erik C, Slater, Louise H, Mark, Kevin G, Kawate, Tomohiko, Monks, Brian G, Stutz, Andrea, Latz, Eicke, Hung, Deborah T
Published in Nature chemical biology (01.06.2013)
Published in Nature chemical biology (01.06.2013)
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Journal Article
177: The NLRP3 inflammasome is regulated by phosphorylation and ubiquitinylation
Stutz, Andrea, Horvath, Gabor L., Stahl, Rainer, Franklin, Bernardo S., Kolbe, Carl-Christian L., Geyer, Matthias, Meissner, Felix, Latz, Eicke
Published in Cytokine (Philadelphia, Pa.) (01.11.2014)
Published in Cytokine (Philadelphia, Pa.) (01.11.2014)
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Journal Article
177
Stutz, Andrea, Horvath, Gabor L., Stahl, Rainer, Franklin, Bernardo S., Kolbe, Carl-Christian L., Geyer, Matthias, Meissner, Felix, Latz, Eicke
Published in Cytokine (Philadelphia, Pa.) (01.11.2014)
Published in Cytokine (Philadelphia, Pa.) (01.11.2014)
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Journal Article
Erratum: Chemical genetics reveals a kinase-independent role for protein kinase R in pyroptosis
Hett, Erik C, Slater, Louise H, Mark, Kevin G, Kawate, Tomohiko, Monks, Brian G, Stutz, Andrea, Latz, Eicke, Hung, Deborah T
Published in Nature chemical biology (17.06.2013)
Published in Nature chemical biology (17.06.2013)
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Journal Article
A small molecule inhibitior of the NLRP3 inflammasome is a potential therapeutic for inflammatory diseases
Coll, Rebecca C., Robertson, Avril A. B., Chae, Jae Jin, Higgins, Sarah C., Muñoz-Planillo, Raúl, Inserra, Marco C., Vetter, Irina, Dungan, Lara S., Monks, Brian G., Stutz, Andrea, Croker, Daniel E., Butler, Mark S., Haneklaus, Moritz, Sutton, Caroline E., Núñez, Gabriel, Latz, Eicke, Kastner, Daniel L., Mills, Kingston H. G., Masters, Seth L., Schroder, Kate, Cooper, Matthew A., O’Neill, Luke A. J.
Published in Nature medicine (16.02.2015)
Published in Nature medicine (16.02.2015)
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Journal Article
Activation of the NLRP3 Inflammasome by IAV Virulence Protein PB1-F2 Contributes to Severe Pathophysiology and Disease: e1003392
McAuley, Julie L, Tate, Michelle D, MacKenzie-Kludas, Charley J, Pinar, Anita, Zeng, Weiguang, Stutz, Andrea, Latz, Eicke, Brown, Lorena E, Mansell, Ashley
Published in PLoS pathogens (01.05.2013)
Published in PLoS pathogens (01.05.2013)
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Journal Article
ASC has extracellular and prionoid activities that propagate inflammation
Franklin, Bernardo S., Bossaller, Lukas, De Nardo, Dominic, Ratter, Jacqueline M., Stutz, Andrea, Engels, Gudrun, Brenker, Christoph, Nordhoff, Mark, Mirandola, Sandra R., Al-Amoudi, Ashraf, Mangan, Matthew, Zimmer, Sebastian, Monks, Brian, Fricke, Martin, Schmidt, Reinhold E., Espevik, Terje, Jones, Bernadette, Jarnicki, Andrew G., Hansbro, Philip M., Busto, Patricia, Marshak-Rothstein, Ann, Hornemann, Simone, Aguzzi, Adriano, Kastenmüller, Wolfgang, Latz, Eicke
Published in Nature immunology (22.06.2014)
Published in Nature immunology (22.06.2014)
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Journal Article
Innate immune receptors for nucleic acids
Stutz, Andrea, Bertheloot, Damien, Latz, Eicke
Published in Methods in molecular biology (Clifton, N.J.) (01.01.2011)
Published in Methods in molecular biology (Clifton, N.J.) (01.01.2011)
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