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Published in PloS one (23.09.2010)
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Pyrazolopyridine inhibitors of B-RafV600E. Part 4: Rational design and kinase selectivity profile of cell potent type II inhibitors
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Published in Bioorganic & medicinal chemistry letters (01.10.2012)
Published in Bioorganic & medicinal chemistry letters (01.10.2012)
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Pyrazolopyridine inhibitors of B-RafV600E. Part 2: Structure–activity relationships
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Published in Bioorganic & medicinal chemistry letters (15.09.2011)
Published in Bioorganic & medicinal chemistry letters (15.09.2011)
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Pyrazolopyridine inhibitors of B-Raf(V600E). Part 4: Rational design and kinase selectivity profile of cell potent type II inhibitors
Wenglowsky, Steve, Moreno, David, Laird, Ellen R., Gloor, Susan L., Ren, Li, Risom, Tyler, Rudolph, Joachim, Sturgis, Hillary L., Voegtli, Walter C.
Published in Bioorganic & medicinal chemistry letters (01.10.2012)
Published in Bioorganic & medicinal chemistry letters (01.10.2012)
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Discovery of 2‑Pyridylureas as Glucokinase Activators
Hinklin, Ronald J, Aicher, Thomas D, Anderson, Deborah A, Baer, Brian R, Boyd, Steven A, Condroski, Kevin R, DeWolf, Walter E, Kraser, Christopher F, McVean, Maralee, Rhodes, Susan P, Sturgis, Hillary L, Voegtli, Walter C, Williams, Lance, Houze, Jonathan B
Published in Journal of medicinal chemistry (09.10.2014)
Published in Journal of medicinal chemistry (09.10.2014)
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Highly potent and selective 3-N-methylquinazoline-4(3H)-one based inhibitors of B-Raf(V600E) kinase
Wenglowsky, Steve, Ren, Li, Grina, Jonas, Hansen, Joshua D, Laird, Ellen R, Moreno, David, Dinkel, Victoria, Gloor, Susan L, Hastings, Gregg, Rana, Sumeet, Rasor, Kevin, Sturgis, Hillary L, Voegtli, Walter C, Vigers, Guy, Willis, Brandon, Mathieu, Simon, Rudolph, Joachim
Published in Bioorganic & medicinal chemistry letters (15.04.2014)
Published in Bioorganic & medicinal chemistry letters (15.04.2014)
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Pyrazolopyridine Inhibitors of B-Raf(V600E). Part 1: The Development of Selective, Orally Bioavailable, and Efficacious Inhibitors
Wenglowsky, Steve, Ren, Li, Ahrendt, Kateri A, Laird, Ellen R, Aliagas, Ignacio, Alicke, Bruno, Buckmelter, Alex J, Choo, Edna F, Dinkel, Victoria, Feng, Bainian, Gloor, Susan L, Gould, Stephen E, Gross, Stefan, Gunzner-Toste, Janet, Hansen, Joshua D, Hatzivassiliou, Georgia, Liu, Bonnie, Malesky, Kim, Mathieu, Simon, Newhouse, Brad, Raddatz, Nicholas J, Ran, Yingqing, Rana, Sumeet, Randolph, Nikole, Risom, Tyler, Rudolph, Joachim, Savage, Scott, Selby, LeAnn T, Shrag, Michael, Song, Kyung, Sturgis, Hillary L, Voegtli, Walter C, Wen, Zhaoyang, Willis, Brandon S, Woessner, Richard D, Wu, Wen-I, Young, Wendy B, Grina, Jonas
Published in ACS medicinal chemistry letters (12.05.2011)
Published in ACS medicinal chemistry letters (12.05.2011)
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The discovery of potent and selective pyridopyrimidin-7-one based inhibitors of B-RafV600E kinase
Ren, Li, Ahrendt, Kateri A., Grina, Jonas, Laird, Ellen R., Buckmelter, Alex J., Hansen, Joshua D., Newhouse, Brad, Moreno, David, Wenglowsky, Steve, Dinkel, Victoria, Gloor, Susan L., Hastings, Gregg, Rana, Sumeet, Rasor, Kevin, Risom, Tyler, Sturgis, Hillary L., Voegtli, Walter C., Mathieu, Simon
Published in Bioorganic & medicinal chemistry letters (15.05.2012)
Published in Bioorganic & medicinal chemistry letters (15.05.2012)
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Highly potent and selective 3-N-methylquinazoline-4(3H)-one based inhibitors of B-RafV600E kinase
Wenglowsky, Steve, Ren, Li, Grina, Jonas, Hansen, Joshua D., Laird, Ellen R., Moreno, David, Dinkel, Victoria, Gloor, Susan L., Hastings, Gregg, Rana, Sumeet, Rasor, Kevin, Sturgis, Hillary L., Voegtli, Walter C., Vigers, Guy, Willis, Brandon, Mathieu, Simon, Rudolph, Joachim
Published in Bioorganic & medicinal chemistry letters (01.04.2014)
Published in Bioorganic & medicinal chemistry letters (01.04.2014)
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Highly potent and selective 3-N-methylquinazoline-4(3H)-one based inhibitors of B-Raf super(V600E) kinase
Wenglowsky, Steve, Ren, Li, Grina, Jonas, Hansen, Joshua D, Laird, Ellen R, Moreno, David, Dinkel, Victoria, Gloor, Susan L, Hastings, Gregg, Rana, Sumeet, Rasor, Kevin, Sturgis, Hillary L, Voegtli, Walter C, Vigers, Guy, Willis, Brandon, Mathieu, Simon, Rudolph, Joachim
Published in Bioorganic & medicinal chemistry letters (01.04.2014)
Published in Bioorganic & medicinal chemistry letters (01.04.2014)
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Pyrazolopyridine inhibitors of B-Raf super(V600E. Part 2: Structure-activity relationships)
Wenglowsky, Steve, Ahrendt, Kateri A, Buckmelter, Alex J, Feng, Bainian, Gloor, Susan L, Gradl, Stefan, Grina, Jonas, Hansen, Joshua D, Laird, Ellen R, Lunghofer, Paul, Mathieu, Simon, Moreno, David, Newhouse, Brad, Ren, Li, Risom, Tyler, Rudolph, Joachim, Seo, Jeongbeob, Sturgis, Hillary L, Voegtli, Walter C, Wen, Zhaoyang
Published in Bioorganic & medicinal chemistry letters (15.09.2011)
Published in Bioorganic & medicinal chemistry letters (15.09.2011)
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Journal Article
Pyrazolopyridine Inhibitors of B-Raf V600E . Part 1: The Development of Selective, Orally Bioavailable, and Efficacious Inhibitors
Wenglowsky, Steve, Ren, Li, Ahrendt, Kateri A., Laird, Ellen R., Aliagas, Ignacio, Alicke, Bruno, Buckmelter, Alex J., Choo, Edna F., Dinkel, Victoria, Feng, Bainian, Gloor, Susan L., Gould, Stephen E., Gross, Stefan, Gunzner-Toste, Janet, Hansen, Joshua D., Hatzivassiliou, Georgia, Liu, Bonnie, Malesky, Kim, Mathieu, Simon, Newhouse, Brad, Raddatz, Nicholas J., Ran, Yingqing, Rana, Sumeet, Randolph, Nikole, Risom, Tyler, Rudolph, Joachim, Savage, Scott, Selby, LeAnn T., Shrag, Michael, Song, Kyung, Sturgis, Hillary L., Voegtli, Walter C., Wen, Zhaoyang, Willis, Brandon S., Woessner, Richard D., Wu, Wen-I, Young, Wendy B., Grina, Jonas
Published in ACS medicinal chemistry letters (12.05.2011)
Published in ACS medicinal chemistry letters (12.05.2011)
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Journal Article
Pyrazolopyridine Inhibitors of B-RafV600E. Part 1: The Development of Selective, Orally Bioavailable, and Efficacious Inhibitors
Wenglowsky, Steve, Ren, Li, Ahrendt, Kateri A, Laird, Ellen R, Aliagas, Ignacio, Alicke, Bruno, Buckmelter, Alex J, Choo, Edna F, Dinkel, Victoria, Feng, Bainian, Gloor, Susan L, Gould, Stephen E, Gross, Stefan, Gunzner-Toste, Janet, Hansen, Joshua D, Hatzivassiliou, Georgia, Liu, Bonnie, Malesky, Kim, Mathieu, Simon, Newhouse, Brad, Raddatz, Nicholas J, Ran, Yingqing, Rana, Sumeet, Randolph, Nikole, Risom, Tyler, Rudolph, Joachim, Savage, Scott, Selby, LeAnn T, Shrag, Michael, Song, Kyung, Sturgis, Hillary L, Voegtli, Walter C, Wen, Zhaoyang, Willis, Brandon S, Woessner, Richard D, Wu, Wen-I, Young, Wendy B, Grina, Jonas
Published in ACS medicinal chemistry letters (08.03.2011)
Published in ACS medicinal chemistry letters (08.03.2011)
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