A genome-wide association study of blood cell morphology identifies cellular proteins implicated in disease aetiology
Akbari, Parsa, Vuckovic, Dragana, Stefanucci, Luca, Jiang, Tao, Kundu, Kousik, Kreuzhuber, Roman, Bao, Erik L, Collins, Janine H, Downes, Kate, Grassi, Luigi, Guerrero, Jose A, Kaptoge, Stephen, Knight, Julian C, Meacham, Stuart, Sambrook, Jennifer, Seyres, Denis, Stegle, Oliver, Verboon, Jeffrey M, Walter, Klaudia, Watkins, Nicholas A, Danesh, John, Roberts, David J, Di Angelantonio, Emanuele, Sankaran, Vijay G, Frontini, Mattia, Burgess, Stephen, Kuijpers, Taco, Peters, James E, Butterworth, Adam S, Ouwehand, Willem H, Soranzo, Nicole, Astle, William J
Published in Nature communications (18.08.2023)
Published in Nature communications (18.08.2023)
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Maps of open chromatin guide the functional follow-up of genome-wide association signals: application to hematological traits
Paul, Dirk S, Nisbet, James P, Yang, Tsun-Po, Meacham, Stuart, Rendon, Augusto, Hautaviita, Katta, Tallila, Jonna, White, Jacqui, Tijssen, Marloes R, Sivapalaratnam, Suthesh, Basart, Hanneke, Trip, Mieke D, Göttgens, Berthold, Soranzo, Nicole, Ouwehand, Willem H, Deloukas, Panos
Published in PLoS genetics (01.06.2011)
Published in PLoS genetics (01.06.2011)
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The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease
Astle, William J., Elding, Heather, Jiang, Tao, Allen, Dave, Ruklisa, Dace, Mann, Alice L., Mead, Daniel, Bouman, Heleen, Riveros-Mckay, Fernando, Kostadima, Myrto A., Lambourne, John J., Sivapalaratnam, Suthesh, Downes, Kate, Kundu, Kousik, Bomba, Lorenzo, Berentsen, Kim, Bradley, John R., Daugherty, Louise C., Delaneau, Olivier, Freson, Kathleen, Garner, Stephen F., Grassi, Luigi, Guerrero, Jose, Haimel, Matthias, Janssen-Megens, Eva M., Kaan, Anita, Kamat, Mihir, Kim, Bowon, Mandoli, Amit, Marchini, Jonathan, Martens, Joost H.A., Meacham, Stuart, Megy, Karyn, O’Connell, Jared, Petersen, Romina, Sharifi, Nilofar, Sheard, Simon M., Staley, James R., Tuna, Salih, van der Ent, Martijn, Walter, Klaudia, Wang, Shuang-Yin, Wheeler, Eleanor, Wilder, Steven P., Iotchkova, Valentina, Moore, Carmel, Sambrook, Jennifer, Stunnenberg, Hendrik G., Di Angelantonio, Emanuele, Kaptoge, Stephen, Kuijpers, Taco W., Carrillo-de-Santa-Pau, Enrique, Juan, David, Rico, Daniel, Valencia, Alfonso, Chen, Lu, Ge, Bing, Vasquez, Louella, Kwan, Tony, Garrido-Martín, Diego, Watt, Stephen, Yang, Ying, Guigo, Roderic, Beck, Stephan, Paul, Dirk S., Pastinen, Tomi, Bujold, David, Bourque, Guillaume, Frontini, Mattia, Danesh, John, Roberts, David J., Ouwehand, Willem H., Butterworth, Adam S., Soranzo, Nicole
Published in Cell (17.11.2016)
Published in Cell (17.11.2016)
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Transcriptional diversity during lineage commitment of human blood progenitors
Chen, Lu, Kostadima, Myrto, Martens, Joost H. A., Canu, Giovanni, Garcia, Sara P., Turro, Ernest, Downes, Kate, Macaulay, Iain C., Bielczyk-Maczynska, Ewa, Coe, Sophia, Farrow, Samantha, Poudel, Pawan, Burden, Frances, Jansen, Sjoert B. G., Astle, William J., Attwood, Antony, Bariana, Tadbir, de Bono, Bernard, Breschi, Alessandra, Chambers, John C., Consortium, BRIDGE, Choudry, Fizzah A., Clarke, Laura, Coupland, Paul, van der Ent, Martijn, Erber, Wendy N., Jansen, Joop H., Favier, Rémi, Fenech, Matthew E., Foad, Nicola, Freson, Kathleen, van Geet, Chris, Gomez, Keith, Guigo, Roderic, Hampshire, Daniel, Kelly, Anne M., Kerstens, Hindrik H. D., Kooner, Jaspal S., Laffan, Michael, Lentaigne, Claire, Labalette, Charlotte, Martin, Tiphaine, Meacham, Stuart, Mumford, Andrew, Nürnberg, Sylvia, Palumbo, Emilio, van der Reijden, Bert A., Richardson, David, Sammut, Stephen J., Slodkowicz, Greg, Tamuri, Asif U., Vasquez, Louella, Voss, Katrin, Watt, Stephen, Westbury, Sarah, Flicek, Paul, Loos, Remco, Goldman, Nick, Bertone, Paul, Read, Randy J., Richardson, Sylvia, Cvejic, Ana, Soranzo, Nicole, Ouwehand, Willem H., Stunnenberg, Hendrik G., Frontini, Mattia, Rendon, Augusto
Published in Science (American Association for the Advancement of Science) (26.09.2014)
Published in Science (American Association for the Advancement of Science) (26.09.2014)
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Nbeal2 interacts with Dock7, Sec16a, and Vac14
Mayer, Louisa, Jasztal, Maria, Pardo, Mercedes, Aguera de Haro, Salvadora, Collins, Janine, Bariana, Tadbir K., Smethurst, Peter A., Grassi, Luigi, Petersen, Romina, Nurden, Paquita, Favier, Rémi, Yu, Lu, Meacham, Stuart, Astle, William J., Choudhary, Jyoti, Yue, Wyatt W., Ouwehand, Willem H., Guerrero, Jose A.
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Published in Blood (01.03.2018)
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Using EMBL‐EBI Services via Web Interface and Programmatically via Web Services
Madeira, Fábio, Madhusoodanan, Nandana, Lee, Joonheung, Eusebi, Alberto, Niewielska, Ania, Tivey, Adrian R. N., Meacham, Stuart, Lopez, Rodrigo, Butcher, Sarah
Published in Current protocols (01.06.2024)
Published in Current protocols (01.06.2024)
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Platelet function is modified by common sequence variation in megakaryocyte super enhancers
Petersen, Romina, Lambourne, John J, Javierre, Biola M, Grassi, Luigi, Kreuzhuber, Roman, Ruklisa, Dace, Rosa, Isabel M, Tomé, Ana R, Elding, Heather, van Geffen, Johanna P, Jiang, Tao, Farrow, Samantha, Cairns, Jonathan, Al-Subaie, Abeer M, Ashford, Sofie, Attwood, Antony, Batista, Joana, Bouman, Heleen, Burden, Frances, Choudry, Fizzah A, Clarke, Laura, Flicek, Paul, Garner, Stephen F, Haimel, Matthias, Kempster, Carly, Ladopoulos, Vasileios, Lenaerts, An-Sofie, Materek, Paulina M, McKinney, Harriet, Meacham, Stuart, Mead, Daniel, Nagy, Magdolna, Penkett, Christopher J, Rendon, Augusto, Seyres, Denis, Sun, Benjamin, Tuna, Salih, van der Weide, Marie-Elise, Wingett, Steven W, Martens, Joost H, Stegle, Oliver, Richardson, Sylvia, Vallier, Ludovic, Roberts, David J, Freson, Kathleen, Wernisch, Lorenz, Stunnenberg, Hendrik G, Danesh, John, Fraser, Peter, Soranzo, Nicole, Butterworth, Adam S, Heemskerk, Johan W, Turro, Ernest, Spivakov, Mikhail, Ouwehand, Willem H, Astle, William J, Downes, Kate, Kostadima, Myrto, Frontini, Mattia
Published in Nature communications (13.07.2017)
Published in Nature communications (13.07.2017)
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Human phenotype ontology annotation and cluster analysis to unravel genetic defects in 707 cases with unexplained bleeding and platelet disorders
Westbury, Sarah K, Turro, Ernest, Greene, Daniel, Lentaigne, Claire, Kelly, Anne M, Bariana, Tadbir K, Simeoni, Ilenia, Pillois, Xavier, Attwood, Antony, Austin, Steve, Jansen, Sjoert Bg, Bakchoul, Tamam, Crisp-Hihn, Abi, Erber, Wendy N, Favier, Rémi, Foad, Nicola, Gattens, Michael, Jolley, Jennifer D, Liesner, Ri, Meacham, Stuart, Millar, Carolyn M, Nurden, Alan T, Peerlinck, Kathelijne, Perry, David J, Poudel, Pawan, Schulman, Sol, Schulze, Harald, Stephens, Jonathan C, Furie, Bruce, Robinson, Peter N, van Geet, Chris, Rendon, Augusto, Gomez, Keith, Laffan, Michael A, Lambert, Michele P, Nurden, Paquita, Ouwehand, Willem H, Richardson, Sylvia, Mumford, Andrew D, Freson, Kathleen
Published in Genome medicine (09.04.2015)
Published in Genome medicine (09.04.2015)
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A synthesis approach of mouse studies to identify genes and proteins in arterial thrombosis and bleeding
Baaten, Constance C.F.M.J., Meacham, Stuart, de Witt, Susanne M., Feijge, Marion A.H., Adams, David J., Akkerman, Jan-Willem N., Cosemans, Judith M.E.M., Grassi, Luigi, Jupe, Steve, Kostadima, Myrto, Mattheij, Nadine J.A., Prins, Martin H., Ramirez-Solis, Ramiro, Soehnlein, Oliver, Swieringa, Frauke, Weber, Christian, White, Jacqueline K., Ouwehand, Willem H., Heemskerk, Johan W.M.
Published in Blood (13.12.2018)
Published in Blood (13.12.2018)
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Correction: Maps of Open Chromatin Guide the Functional Follow-Up of Genome-Wide Association Signals: Application to Hematological Traits
Dirk S. Paul, James P. Nisbet, Tsun-Po Yang, Stuart Meacham, Augusto Rendon, Katta Hautaviita, Jonna Tallila, Jacqui White, Marloes R. Tijssen, Suthesh Sivapalaratnam, Hanneke Basart, Mieke D. Trip, Berthold Göttgens, Nicole Soranzo, Willem H. Ouwehand, Panos Deloukas
Published in PLoS genetics (01.07.2011)
Published in PLoS genetics (01.07.2011)
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Correction: Maps of Open Chromatin Guide the Functional Follow-Up of Genome-Wide Association Signals: Application to Hematological Traits
Paul, Dirk S., Nisbet, James P., Yang, Tsun-Po, Meacham, Stuart, Rendon, Augusto, Hautaviita, Katta, Tallila, Jonna, White, Jacqui, Tijssen, Marloes R., Sivapalaratnam, Suthesh, Basart, Hanneke, Trip, Mieke D., Göttgens, Berthold, Soranzo, Nicole, Ouwehand, Willem H., Deloukas, Panos
Published in PLoS genetics (21.07.2011)
Published in PLoS genetics (21.07.2011)
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Maps of Open Chromatin Guide the Functional Follow-Up of Genome-Wide Association Signals: Application to Hematological Traits: e1002139
Paul, Dirk S, Nisbet, James P, Yang, Tsun-Po, Meacham, Stuart, Rendon, Augusto, Hautaviita, Katta, Tallila, Jonna, White, Jacqui, Tijssen, Marloes R, Sivapalaratnam, Suthesh, Basart, Hanneke, Trip, Mieke D, Göttgens, Berthold, Soranzo, Nicole, Ouwehand, Willem H, Deloukas, Panos, Cardiogenics, Consortium, MuTHER, Consortium
Published in PLoS genetics (01.06.2011)
Published in PLoS genetics (01.06.2011)
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