Role of proton-coupled folate transporter in pemetrexed resistance of mesothelioma: clinical evidence and new pharmacological tools
Giovannetti, E., Zucali, P.A., Assaraf, Y.G., Funel, N., Gemelli, M., Stark, M., Thunnissen, E., Hou, Z., Muller, I.B., Struys, E.A., Perrino, M., Jansen, G., Matherly, L.H., Peters, G.J.
Published in Annals of oncology (01.11.2017)
Published in Annals of oncology (01.11.2017)
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Journal Article
Pyridoxine-dependent epilepsy (PDE): Diagnostic and therapeutic queries
Lunsing, R.J, van Spronsen, F.J, Bok, L.A, Struys, E.A, van Karnebeek, C.D
Published in European journal of paediatric neurology (01.06.2017)
Published in European journal of paediatric neurology (01.06.2017)
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Journal Article
Pyridoxine responsive epilepsy caused by a novel homozygous PNPO mutation
Jaeger, B., Abeling, N.G., Salomons, G.S., Struys, E.A., Simas-Mendes, M., Geukers, V.G., Poll-The, B.T.
Published in Molecular genetics and metabolism reports (01.03.2016)
Published in Molecular genetics and metabolism reports (01.03.2016)
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Journal Article
Pyridoxine dependent epilepsy: Is late onset a predictor for favorable outcome?
Bok, L.A, de Rooy, R.L.P, Halbertsma, F.J, Struys, E.A, van Spronsen, F.J, Lunsing, R.J, Schippers, H.M, van Hasselt, P.M, Plecko, B, Wohlrab, G, Wahlen, S, Benoist, J.F, Valence, S
Published in European journal of paediatric neurology (01.06.2017)
Published in European journal of paediatric neurology (01.06.2017)
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Journal Article
Accumulation of thymidine-derived sugars in thymidine phosphorylase overexpressing cells
Bijnsdorp, I.V., Azijli, K., Jansen, E.E., Wamelink, M.M., Jakobs, C., Struys, E.A., Fukushima, M., Kruyt, F.A.E., Peters, G.J.
Published in Biochemical pharmacology (15.09.2010)
Published in Biochemical pharmacology (15.09.2010)
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Journal Article
Validation of a new LC-MS/MS method of the quantification of methotrexate polyglutamates in peripheral blood mononuclear cells
Sundaresan, J., Lin, M., Jansen, G., Hebing, R.C.F., Bulatović-Ćalasan, M., De Jonge, R., Struys, E.A., De Rotte, M.C.F.J.
Published in Clinica chimica acta (01.05.2024)
Published in Clinica chimica acta (01.05.2024)
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Journal Article
An accurate stable isotope dilution gas chromatographic–mass spectrometric approach to the diagnosis of guanidinoacetate methyltransferase deficiency
Struys, E.A., Jansen, E.E.W., ten Brink, H.J., Verhoeven, N.M., van der Knaap, M.S., Jakobs, C.
Published in Journal of pharmaceutical and biomedical analysis (01.12.1998)
Published in Journal of pharmaceutical and biomedical analysis (01.12.1998)
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Journal Article
Conference Proceeding
Quantification of 3-hydroxyglutaric acid in urine, plasma, cerebrospinal fluid and amniotic fluid by stable-isotope dilution negative chemical ionization gas chromatography–mass spectrometry
Schor, D.S.M, Verhoeven, N.M, Struys, E.A, ten Brink, H.J, Jakobs, C
Published in Journal of chromatography. B, Analytical technologies in the biomedical and life sciences (15.11.2002)
Published in Journal of chromatography. B, Analytical technologies in the biomedical and life sciences (15.11.2002)
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Journal Article
Enantiomer-specific and paracrine leukemogenicity of mutant IDH metabolite 2-hydroxyglutarate
Chaturvedi, A, Araujo Cruz, M M, Jyotsana, N, Sharma, A, Goparaju, R, Schwarzer, A, Görlich, K, Schottmann, R, Struys, E A, Jansen, E E, Rohde, C, Müller-Tidow, C, Geffers, R, Göhring, G, Ganser, A, Thol, F, Heuser, M
Published in Leukemia (01.08.2016)
Published in Leukemia (01.08.2016)
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Journal Article
AB0236 Development and validation of a sensitive lc-ms/ms-based method for analysis of enzymatic activity of folylpolyglutamate synthetase and methotrexate polyglutamates in peripheral blood mononuclear cells of rheumatoid arthritis patients
Muller, I.B., Heydari, P., Lin, M., Struys, E.A., Hebing, R., van der Laken, C.J., van Schaardenburg, D., Nurmohamed, M.T., Lems, W.F., Cloos, J., Jansen, G., de Jonge, R.
Published in Annals of the rheumatic diseases (01.06.2018)
Published in Annals of the rheumatic diseases (01.06.2018)
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Journal Article
Analysis of pristanic acid beta-oxidation intermediates in plasma from healthy controls and patients affected with peroxisomal disorders by stable isotope dilution gas chromatography mass spectrometry
Verhoeven, N M, Schor, D S, Struys, E A, Jansen, E E, ten Brink HJ, Wanders, R J, Jakobs, C
Published in Journal of lipid research (01.02.1999)
Published in Journal of lipid research (01.02.1999)
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Journal Article
Direct comparison of quantitative digital PCR and 2-hydroxyglutarate enantiomeric ratio for IDH mutant allele frequency assessment in myeloid malignancy
Wiseman, D H, Struys, E A, Wilks, D P, Clark, C I, Dennis, M W, Jansen, E E W, Salomons, G S, Somervaille, T C P
Published in Leukemia (01.12.2015)
Published in Leukemia (01.12.2015)
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Journal Article
A lymphoblast model for IDH2 gain-of-function activity in d-2-hydroxyglutaric aciduria type II: Novel avenues for biochemical and therapeutic studies
Kranendijk, M., Salomons, G.S., Gibson, K.M., Van Schaftingen, E., Jakobs, C., Struys, E.A.
Published in Biochimica et biophysica acta (01.11.2011)
Published in Biochimica et biophysica acta (01.11.2011)
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Journal Article
Elevated concentrations of sedoheptulose in bloodspots of patients with cystinosis caused by the 57-kb deletion: Implications for diagnostics and neonatal screening
Wamelink, M.M.C., Struys, E.A., Jansen, E.E.W., Blom, H.J., Vilboux, T., Gahl, W.A., Kömhoff, M., Jakobs, C., Levtchenko, E.N.
Published in Molecular genetics and metabolism (01.03.2011)
Published in Molecular genetics and metabolism (01.03.2011)
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Journal Article
d-2-Hydroxyglutaric aciduria in three patients with proven SSADH deficiency: Genetic coincidence or a related biochemical epiphenomenon?
Struys, E.A., Verhoeven, N.M., Salomons, G.S., Berthelot, J., Vianay-Saban, C., Chabrier, S., Thomas, J.A., Tsai, A. Chun-Hui, Gibson, K.M., Jakobs, C.
Published in Molecular genetics and metabolism (01.05.2006)
Published in Molecular genetics and metabolism (01.05.2006)
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Journal Article
Quantitative analysis of urinary acylglycines for the diagnosis of β-oxidation defects using GC-NCI-MS
Costa, C.G., Guérand, W.S., Struys, E.A., Holwerda, U., ten Brink, H.J., Tavares de Almeida, I., Duran, M., Jakobs, C.
Published in Journal of pharmaceutical and biomedical analysis (2000)
Published in Journal of pharmaceutical and biomedical analysis (2000)
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Journal Article
033 Polyols and a novel leukoencephalopathy
Van Der Knaap, M.S., Wevers, R.A., Struys, E.A., Verhoeven, N.M., Pouwels, P.J.W., Jakobs, C.
Published in European journal of paediatric neurology (1999)
Published in European journal of paediatric neurology (1999)
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Journal Article
Combined method for the determination of γ-aminobutyric and β-alanine in cerebrospinal fluid by stable isotope dilution mass spectrometry
Struys, E.A, Guérand, W.S, ten Brink, H.J, Jakobs, C
Published in Journal of chromatography. B, Biomedical sciences and applications (10.09.1999)
Published in Journal of chromatography. B, Biomedical sciences and applications (10.09.1999)
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Journal Article