Multiple Roles of Cyclin-Dependent Kinase 4/6 Inhibitors in Cancer Therapy
ROBERTS, Patrick J, BISI, John E, STRUM, Jay C, COMBEST, Austin J, DARR, David B, USARY, Jerry E, ZAMBONI, William C, WONG, Kwok-Kin, PEROU, Charles M, SHARPLESS, Norman E
Published in JNCI : Journal of the National Cancer Institute (21.03.2012)
Published in JNCI : Journal of the National Cancer Institute (21.03.2012)
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Journal Article
MicroRNA 132 Regulates Nutritional Stress-Induced Chemokine Production through Repression of SirT1
Strum, Jay C, Johnson, Jennifer H, Ward, James, Xie, Hongbo, Feild, John, Hester, Austin, Alford, Alexander, Waters, K. Michelle
Published in Molecular endocrinology (Baltimore, Md.) (01.11.2009)
Published in Molecular endocrinology (Baltimore, Md.) (01.11.2009)
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Journal Article
Adipose Mitochondrial Biogenesis Is Suppressed in db/db and High-Fat Diet–Fed Mice and Improved by Rosiglitazone
RONG, James X, YANG QIU, STRUM, Jay C, RYAN, Terence E, HANSEN, Michael K, LEI ZHU, ZHANG, Vivian, MI XIE, OKAMOTO, Yuji, MATTIE, Michael D, HIGASHIYAMA, Hiroyuki, ASANO, Satoshi
Published in Diabetes (New York, N.Y.) (01.07.2007)
Published in Diabetes (New York, N.Y.) (01.07.2007)
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Journal Article
Activation of Peroxisome Proliferator–Activated Receptor (PPAR)δ Promotes Reversal of Multiple Metabolic Abnormalities, Reduces Oxidative Stress, and Increases Fatty Acid Oxidation in Moderately Obese Men
RISERUS, Ulf, SPRECHER, Dennis, STRUM, Jay C, BASU, Samar, CHEESEMAN, Jane, FIELDING, Barbara A, HUMPHREYS, Sandy M, DANOFF, Theodore, MOORE, Niall R, MURGATROYD, Peter, O'RAHILLY, Stephen, SUTTON, Pauline, JOHNSON, Tony, WILLSON, Tim, HASSALL, David, FRAYN, Keith N, KARPE, Fredrik, OLSON, Eric, HIRSCHBERG, Sandra, AIXUE LIU, ZEKE FANG, HEGDE, Priti, RICHARDS, Duncan, SAROV-BLAT, Leli
Published in Diabetes (New York, N.Y.) (01.02.2008)
Published in Diabetes (New York, N.Y.) (01.02.2008)
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Journal Article
The Orphan G Protein-coupled Receptors GPR41 and GPR43 Are Activated by Propionate and Other Short Chain Carboxylic Acids
Brown, Andrew J, Goldsworthy, Susan M, Barnes, Ashley A, Eilert, Michelle M, Tcheang, Lili, Daniels, Dion, Muir, Alison I, Wigglesworth, Mark J, Kinghorn, Ian, Fraser, Neil J, Pike, Nicholas B, Strum, Jay C, Steplewski, Klaudia M, Murdock, Paul R, Holder, Julie C, Marshall, Fiona H, Szekeres, Philip G, Wilson, Shelagh, Ignar, Diane M, Foord, Steve M, Wise, Alan, Dowell, Simon J
Published in The Journal of biological chemistry (28.03.2003)
Published in The Journal of biological chemistry (28.03.2003)
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Journal Article
The Orphan G Protein-coupled Receptor GPR40 Is Activated by Medium and Long Chain Fatty Acids
Briscoe, Celia P, Tadayyon, Mohammad, Andrews, John L, Benson, William G, Chambers, Jon K, Eilert, Michelle M, Ellis, Catherine, Elshourbagy, Nabil A, Goetz, Aaron S, Minnick, Dana T, Murdock, Paul R, Sauls, Jr, Howard R, Shabon, Usman, Spinage, Lisa D, Strum, Jay C, Szekeres, Philip G, Tan, Kong B, Way, James M, Ignar, Diane M, Wilson, Shelagh, Muir, Alison I
Published in The Journal of biological chemistry (28.03.2003)
Published in The Journal of biological chemistry (28.03.2003)
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Journal Article
CDK4/6 Therapeutic Intervention and Viable Alternative to Taxanes in CRPC
Stice, James P, Wardell, Suzanne E, Norris, John D, Yllanes, Alexander P, Alley, Holly M, Haney, Victoria O, White, Hannah S, Safi, Rachid, Winter, Peter S, Cocce, Kimberly J, Kishton, Rigel J, Lawrence, Scott A, Strum, Jay C, McDonnell, Donald P
Published in Molecular cancer research (01.06.2017)
Published in Molecular cancer research (01.06.2017)
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Journal Article
CDK4/6 Inhibition Augments Antitumor Immunity by Enhancing T-cell Activation
Deng, Jiehui, Wang, Eric S, Jenkins, Russell W, Li, Shuai, Dries, Ruben, Yates, Kathleen, Chhabra, Sandeep, Huang, Wei, Liu, Hongye, Aref, Amir R, Ivanova, Elena, Paweletz, Cloud P, Bowden, Michaela, Zhou, Chensheng W, Herter-Sprie, Grit S, Sorrentino, Jessica A, Bisi, John E, Lizotte, Patrick H, Merlino, Ashley A, Quinn, Max M, Bufe, Lauren E, Yang, Annan, Zhang, Yanxi, Zhang, Hua, Gao, Peng, Chen, Ting, Cavanaugh, Megan E, Rode, Amanda J, Haines, Eric, Roberts, Patrick J, Strum, Jay C, Richards, William G, Lorch, Jochen H, Parangi, Sareh, Gunda, Viswanath, Boland, Genevieve M, Bueno, Raphael, Palakurthi, Sangeetha, Freeman, Gordon J, Ritz, Jerome, Haining, W Nicholas, Sharpless, Norman E, Arthanari, Haribabu, Shapiro, Geoffrey I, Barbie, David A, Gray, Nathanael S, Wong, Kwok-Kin
Published in Cancer discovery (01.02.2018)
Published in Cancer discovery (01.02.2018)
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Journal Article
Transient CDK4/6 inhibition protects hematopoietic stem cells from chemotherapy-induced exhaustion
He, Shenghui, Roberts, Patrick J, Sorrentino, Jessica A, Bisi, John E, Storrie-White, Hannah, Tiessen, Renger G, Makhuli, Karenann M, Wargin, William A, Tadema, Henko, van Hoogdalem, Ewoud-Jan, Strum, Jay C, Malik, Rajesh, Sharpless, Norman E
Published in Science translational medicine (26.04.2017)
Published in Science translational medicine (26.04.2017)
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Journal Article
Rosiglitazone Induces Mitochondrial Biogenesis in Differentiated Murine 3T3-L1 and C3H/10T1/2 Adipocytes
Kashatus, Jennifer A., Remlinger, Katja S., Bing, Nan, Crosby, Renae M., Jackson, Tymissha K., Witherspoon, Sam M., Moore, John T., Ryan, Terence E., Neill, Sue D., Strum, Jay C., Rong, James X., Zhang, Vivian, Waters, K. Michelle, Johnson, Jennifer H., Klein, Jean-Louis D., Qiu, Yang, Xie, Mi
Published in PPAR Research (01.01.2011)
Published in PPAR Research (01.01.2011)
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Journal Article
G1T48, an oral selective estrogen receptor degrader, and the CDK4/6 inhibitor lerociclib inhibit tumor growth in animal models of endocrine-resistant breast cancer
Andreano, Kaitlyn J., Wardell, Suzanne E., Baker, Jennifer G., Desautels, Taylor K., Baldi, Robert, Chao, Christina A., Heetderks, Kendall A., Bae, Yeeun, Xiong, Rui, Tonetti, Debra A., Gutgesell, Lauren M., Zhao, Jiong, Sorrentino, Jessica A., Thompson, Delita A., Bisi, John E., Strum, Jay C., Thatcher, Gregory R. J., Norris, John D.
Published in Breast cancer research and treatment (01.04.2020)
Published in Breast cancer research and treatment (01.04.2020)
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Journal Article
CDK4/6 inhibition enhances antitumor efficacy of chemotherapy and immune checkpoint inhibitor combinations in preclinical models and enhances T-cell activation in patients with SCLC receiving chemotherapy
Lai, Anne Y, Sorrentino, Jessica A, Dragnev, Konstantin H, Weiss, Jared M, Owonikoko, Taofeek K, Rytlewski, Julie A, Hood, Jill, Yang, Zhao, Malik, Rajesh K, Strum, Jay C, Roberts, Patrick J
Published in Journal for immunotherapy of cancer (01.10.2020)
Published in Journal for immunotherapy of cancer (01.10.2020)
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Journal Article
Preclinical development of G1T38: A novel, potent and selective inhibitor of cyclin dependent kinases 4/6 for use as an oral antineoplastic in patients with CDK4/6 sensitive tumors
Bisi, John E, Sorrentino, Jessica A, Jordan, Jamie L, Darr, David D, Roberts, Patrick J, Tavares, Francis X, Strum, Jay C
Published in Oncotarget (27.06.2017)
Published in Oncotarget (27.06.2017)
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Journal Article
Rosiglitazone Induces Mitochondrial Biogenesis in Mouse Brain
Strum, Jay C., Shehee, Ron, Virley, David, Richardson, Jill, Mattie, Michael, Selley, Paula, Ghosh, Sujoy, Nock, Christina, Saunders, Ann, Roses, Allen
Published in Journal of Alzheimer's disease (01.03.2007)
Published in Journal of Alzheimer's disease (01.03.2007)
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Journal Article
PRESERVATION OF IMMUNE RESPONSE DURING CHEMOTHERAPY REGIMENS
LAI ANNE Y, SORRENTINO JESSICA A, STRUM JAY C, ROBERTS PATRICK JOSEPH
Year of Publication 23.02.2024
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Year of Publication 23.02.2024
Patent
PRESERVATION OF IMMUNE RESPONSE DURING CHEMOTHERAPY REGIMENS
LAI ANNE Y, SORRENTINO JESSICA A, STRUM JAY C, ROBERTS PATRICK JOSEPH
Year of Publication 22.02.2024
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Year of Publication 22.02.2024
Patent
PRESERVATION OF IMMUNE RESPONSE DURING CHEMOTHERAPY REGIMENS
LAI ANNE Y, SORRENTINO JESSICA A, STRUM JAY C, ROBERTS PATRICK JOSEPH
Year of Publication 22.02.2024
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Year of Publication 22.02.2024
Patent