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Ni(II) mixed-ligand chelates based on 2-hydroxy-1-naphthaldehyde as antimicrobial agents: Synthesis, characterization, and molecular modeling
Ismael, Mohamed, Abdel-Mawgoud, Abdel-Mawgoud M., Rabia, Mostafa K., Abdou, Aly
Published in Journal of molecular liquids (15.05.2021)
Published in Journal of molecular liquids (15.05.2021)
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Modulating the complement system through epitope-specific inhibition by complement C3 inhibitors
Chen, Zhidong, Wang, Mingshuang, Duan, Wenqian, Xia, Yi, Liu, Huiqin, Qian, Feng
Published in The Journal of biological chemistry (01.03.2025)
Published in The Journal of biological chemistry (01.03.2025)
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Discovery and optimization of a novel series of highly CNS penetrant M4 PAMs based on a 5,6-dimethyl-4-(piperidin-1-yl)thieno[2,3-d]pyrimidine core
Wood, Michael R., Noetzel, Meredith J., Engers, Julie L., Bollinger, Katrina A., Melancon, Bruce J., Tarr, James C., Han, Changho, West, Mary, Gregro, Alison R., Lamsal, Atin, Chang, Sichen, Ajmera, Sonia, Smith, Emery, Chase, Peter, Hodder, Peter S., Bubser, Michael, Jones, Carrie K., Hopkins, Corey R., Emmitte, Kyle A., Niswender, Colleen M., Wood, Michael W., Duggan, Mark E., Conn, P. Jeffrey, Bridges, Thomas M., Lindsley, Craig W.
Published in Bioorganic & medicinal chemistry letters (01.07.2016)
Published in Bioorganic & medicinal chemistry letters (01.07.2016)
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Structure-activity correlations for peptaibols obtained from clade Longibrachiatum of Trichoderma: A combined experimental and computational approach
Balázs, Dóra, Marik, Tamás, Szekeres, András, Vágvölgyi, Csaba, Kredics, László, Tyagi, Chetna
Published in Computational and structural biotechnology journal (01.01.2023)
Published in Computational and structural biotechnology journal (01.01.2023)
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Structure-activity-relationship (SAR) for in vitro antileishmanial activity of maesabalide (PX-6518) analogue natural products
Maes, L, Kuypers, K, Vermeersch, M, Cos, P, Pieters, L, Van Puyvelde, L
Published in Planta medica (24.08.2006)
Published in Planta medica (24.08.2006)
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Conference Proceeding
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Discovery and SAR of a novel series of potent, CNS penetrant M4 PAMs based on a non-enolizable ketone core: Challenges in disposition
Wood, Michael R., Noetzel, Meredith J., Tarr, James C., Rodriguez, Alice L., Lamsal, Atin, Chang, Sichen, Foster, Jarrett J., Smith, Emery, Chase, Peter, Hodder, Peter S., Engers, Darren W., Niswender, Colleen M., Brandon, Nicholas J., Wood, Michael W., Duggan, Mark E., Conn, P. Jeffrey, Bridges, Thomas M., Lindsley, Craig W.
Published in Bioorganic & medicinal chemistry letters (01.09.2016)
Published in Bioorganic & medicinal chemistry letters (01.09.2016)
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Discovery of Linagliptin for the Treatment of Type 2 Diabetes Mellitus
Eckhardt, Matthias, Klein, Thomas, Nar, Herbert, Thiemann, Sandra
Published in Successful Drug Discovery (23.01.2015)
Published in Successful Drug Discovery (23.01.2015)
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Book Chapter
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Tyrosinase inhibitory peptides: Structure-activity relationship study on peptide chemical properties, terminal preferences and intracellular regulation of melanogenesis signaling pathways
Yap, Pei-Gee, Gan, Chee-Yuen
Published in Biochimica et biophysica acta. General subjects (01.01.2024)
Published in Biochimica et biophysica acta. General subjects (01.01.2024)
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Allosteric inhibition of tRNA synthetase Gln4 by N-pyrimidinyl-β-thiophenylacrylamides exerts highly selective antifungal activity
Puumala, Emily, Sychantha, David, Lach, Elizabeth, Reeves, Shawn, Nabeela, Sunna, Fogal, Meea, Nigam, AkshatKumar, Johnson, Jarrod W., Aspuru-Guzik, Alán, Shapiro, Rebecca S., Uppuluri, Priya, Kalyaanamoorthy, Subha, Magolan, Jakob, Whitesell, Luke, Robbins, Nicole, Wright, Gerard D., Cowen, Leah E.
Published in Cell chemical biology (18.04.2024)
Published in Cell chemical biology (18.04.2024)
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An Insight into All Tested Small Molecules against Fusarium oxysporum f. sp. Albedinis: A Comparative Review
Kaddouri, Yassine, Benabbes, Redouane, Ouahhoud, Sabir, Abdellattif, Magda, Hammouti, Belkheir, Touzani, Rachid
Published in Molecules (Basel, Switzerland) (22.04.2022)
Published in Molecules (Basel, Switzerland) (22.04.2022)
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Design, Synthesis, and Optimization of Indole Acetic Acid Derivatives as Potent and Selective CRTH2 Receptor Antagonists: Discovery of ACT‐774312
Aissaoui, Hamed, Holdener, Martin, Gnerre, Carmela, Niggemann, Kerstin, Reber, Stefan, Richard, Sylvia, Siegrist, Romain, Boss, Christoph
Published in ChemMedChem (16.05.2023)
Published in ChemMedChem (16.05.2023)
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Chromodomain Ligand Optimization via Target-Class Directed Combinatorial Repurposing
Barnash, Kimberly D, Lamb, Kelsey N, Stuckey, Jacob I, Norris, Jacqueline L, Cholensky, Stephanie H, Kireev, Dmitri B, Frye, Stephen V, James, Lindsey I
Published in ACS chemical biology (16.09.2016)
Published in ACS chemical biology (16.09.2016)
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Discovery and characterization of an iminocoumarin scaffold as an inhibitor of MEKK2 (MAP3K2)
Ahmad, Syed, St. Hilaire, Valentine R., Dandepally, Srinivasa R., Johnson, Gary L., Williams, Alfred L., Scott, John E.
Published in Biochemical and biophysical research communications (29.01.2018)
Published in Biochemical and biophysical research communications (29.01.2018)
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A concise review on anti-breast cancer effectiveness of s-triazines through EGFR kinase inhibition
Tandel, Pooja, Upadhyay, Rachana, Patel, Amit B.
Published in Medicinal chemistry research (01.01.2024)
Published in Medicinal chemistry research (01.01.2024)
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Synthesis of 3,4-diaminobenzoyl derivatives as factor Xa inhibitors
Yang, Jiabin, Su, Guoqiang, Ren, Yu, Chen, Yang
Published in European journal of medicinal chemistry (28.08.2015)
Published in European journal of medicinal chemistry (28.08.2015)
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Rh Catalyzed Selective Hydrogenation of Nitroarenes under Mild Conditions: Understanding the Functional Groups Attached to the Nanoparticles
Tian, Haimeng, Zhou, Junjie, Li, Yunong, Wang, Yiming, Liu, Lei, Ai, Yongjian, Hu, Ze‐Nan, Li, Jifan, Guo, Rongxiu, Liu, Zhibo, Sun, Hong‐bin, Liang, Qionglin
Published in ChemCatChem (21.11.2019)
Published in ChemCatChem (21.11.2019)
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Coumarin-3-carboxylic acid derivatives as potentiators and inhibitors of recombinant and native N-methyl-d-aspartate receptors
Irvine, Mark W., Costa, Blaise M., Volianskis, Arturas, Fang, Guangyu, Ceolin, Laura, Collingridge, Graham L., Monaghan, Daniel T., Jane, David E.
Published in Neurochemistry international (01.09.2012)
Published in Neurochemistry international (01.09.2012)
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Discovery of 3‑({5-Chloro-1-[3-(methylsulfonyl)propyl]‑1H‑indol-2-yl}methyl)-1-(2,2,2-trifluoroethyl)-1,3-dihydro‑2H‑imidazo[4,5‑c]pyridin-2-one (JNJ-53718678), a Potent and Orally Bioavailable Fusion Inhibitor of Respiratory Syncytial Virus
Vendeville, Sandrine, Tahri, Abdellah, Hu, Lili, Demin, Samuel, Cooymans, Ludwig, Vos, Ann, Kwanten, Leen, Van den Berg, Joke, Battles, Michael B, McLellan, Jason S, Koul, Anil, Raboisson, Pierre, Roymans, Dirk, Jonckers, Tim H. M
Published in Journal of medicinal chemistry (13.08.2020)
Published in Journal of medicinal chemistry (13.08.2020)
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