The mixing method used to formulate lipid nanoparticles affects mRNA delivery efficacy and organ tropism
Strelkova Petersen, Daria M., Chaudhary, Namit, Arral, Mariah L., Weiss, Ryan M., Whitehead, Kathryn A.
Published in European journal of pharmaceutics and biopharmaceutics (01.11.2023)
Published in European journal of pharmaceutics and biopharmaceutics (01.11.2023)
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Lipid nanoparticle structure and delivery route during pregnancy dictate mRNA potency, immunogenicity, and maternal and fetal outcomes
Chaudhary, Namit, Newby, Alexandra N, Arral, Mariah L, Yerneni, Saigopalakrishna S, LoPresti, Samuel T, Doerfler, Rose, Petersen, Daria M Strelkova, Montoya, Catalina, Kim, Julie S, Fox, Bethany, Coon, Tiffany, Malaney, Angela, Sadovsky, Yoel, Whitehead, Kathryn A
Published in Proceedings of the National Academy of Sciences - PNAS (12.03.2024)
Published in Proceedings of the National Academy of Sciences - PNAS (12.03.2024)
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Branched‐Tail Lipid Nanoparticles for Intravenous mRNA Delivery to Lung Immune, Endothelial, and Alveolar Cells in Mice
Petersen, Daria M. Strelkova, Weiss, Ryan M., Hajj, Khalid A., Yerneni, Saigopalakrishna S., Chaudhary, Namit, Newby, Alexandra N., Arral, Mariah L., Whitehead, Kathryn A.
Published in Advanced healthcare materials (01.09.2024)
Published in Advanced healthcare materials (01.09.2024)
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Amine headgroups in ionizable lipids drive immune responses to lipid nanoparticles by binding to the receptors TLR4 and CD1d
Chaudhary, Namit, Kasiewicz, Lisa N, Newby, Alexandra N, Arral, Mariah L, Yerneni, Saigopalakrishna S, Melamed, Jilian R, LoPresti, Samuel T, Fein, Katherine C, Strelkova Petersen, Daria M, Kumar, Sushant, Purwar, Rahul, Whitehead, Kathryn A
Published in Nature biomedical engineering (03.10.2024)
Published in Nature biomedical engineering (03.10.2024)
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