AAV-mediated gene transfer of a checkpoint inhibitor in combination with HER2-targeted CAR-NK cells as experimental therapy for glioblastoma
Strecker, M.I., Wlotzka, K., Strassheimer, F., Roller, B., Ludmirski, G., König, S., Röder, J., Opitz, C., Alekseeva, T., Reul, J., Sevenich, L., Tonn, T., Wels, W.S., Steinbach, J.P., Buchholz, C.J., Burger, M.C.
Published in Oncoimmunology (31.12.2022)
Published in Oncoimmunology (31.12.2022)
Get full text
Journal Article
P12.04.A CAR-ENGINEERED PRIMARY NK CELLS SHOW PROMISING EFFECTS AS TARGETED THERAPY AGAINST EGFR-POSITIVE GLIOBLASTOMA
Roller, B, Reindl, L, Strassheimer, F, Ziegener, L, Elleringmann, P, Kiefer, A, Röder, J, Steinbach, J, Wels, W, Ullrich, E, Burger, M
Published in Neuro-oncology (Charlottesville, Va.) (17.10.2024)
Published in Neuro-oncology (Charlottesville, Va.) (17.10.2024)
Get full text
Journal Article
P06.10.A CAR-ENGINEERED PRIMARY NK CELLS SHOW PROMISING EFFECTS AS TARGETED THERAPY AGAINST EGFR-POSITIVE GLIOBLASTOMA
Roller, B, Reindl, L M, Strassheimer, F, Ludmirski, G, Elleringmann, P, Kiefer, A, Röder, J, Steinbach, J P, Wels, W S, Ullrich, E, Burger, M C
Published in Neuro-oncology (Charlottesville, Va.) (08.09.2023)
Published in Neuro-oncology (Charlottesville, Va.) (08.09.2023)
Get full text
Journal Article
P06.06.B PD-1 CHECKPOINT INHIBITION IN CONJUNCTION WITH NK-92/5.28.Z CELLS IS EFFECTIVE IN AN ADVANCED-STAGE GLIOBLASTOMA MOUSE MODEL AND INDUCES A CD4-ENRICHED T CELL RESPONSE
Strassheimer, F, Roller, B, Mildenberger, I C, Macas, J, Alekseeva, T, Tonn, T, Sevenich, L, Reiss, Y, Weber, K J, Plate, K H, Weigert, A, Wels, W S, Steinbach, J P, Burger, M C
Published in Neuro-oncology (Charlottesville, Va.) (08.09.2023)
Published in Neuro-oncology (Charlottesville, Va.) (08.09.2023)
Get full text
Journal Article
OS06.2A Local immunotherapy of glioblastoma via AAV-mediated gene transfer of checkpoint inhibitors in combination with CAR-NK cells
Strecker, M I, Wlotzka, K, Strassheimer, F, Reul, J, Harter, P N, Tonn, T, Steinbach, J P, Wels, W S, Buchholz, C J, Burger, M C
Published in Neuro-oncology (Charlottesville, Va.) (09.09.2021)
Published in Neuro-oncology (Charlottesville, Va.) (09.09.2021)
Get full text
Journal Article
KS05.5.A REPETITIVE INTRACRANIAL INJECTION OF NATURAL KILLER CELLS ENGINEERED WITH A HER2-TARGETED CHIMERIC ANTIGEN RECEPTOR ALONE AND IN COMBINATION WITH SYSTEMIC ANTI-PD-1 CHECKPOINT INHIBITION IN PATIENTS WITH RECURRENT GLIOBLASTOMA
Burger, M C, Ehrend, E, Straßheimer, F, Cakmak, P, Krenzlin, H, Elleringmann, P, Zeiner, P S, Herkt, S C, Poschke, I, Macas, J, Weber, K J, Schupp, J, Lun, J H, Opitz, C, Roller, B, Manns, P, Klinsing, S, Breuer, S, Hehlgans, S, Lee, S, Mildenberger, I C, Ludmirski, G, Hermann, J, Müller, E, Schmitz, M, Mehlitz, M, Senft, C, Harter, P N, Rieger, M A, Rödel, F, Czabanka, M, Ratliff, M, Platten, M, Herold-Mende, C, Ringel, F, Herrmann, E, Hattingen, E, Reiss, Y, Bunse, L, Bonig, H, Plate, K H, Forster, M, Tonn, T, Wels, W S, Steinbach, J P
Published in Neuro-oncology (Charlottesville, Va.) (17.10.2024)
Published in Neuro-oncology (Charlottesville, Va.) (17.10.2024)
Get full text
Journal Article
OS12.6.A Combination therapy of CAR-NK-cells and anti-PD-1 results in high efficacy against advanced-stage glioblastoma in a syngeneic mouse model and induces protective anti-tumor immunity in vivo
Strassheimer, F, Strecker, M I, Alekseeva, T, Macas, J, Demes, M C, Mildenberger, I C, Tonn, T, Wild, P J, Sevenich, L, Reiss, Y, Harter, P N, Plate, K H, Wels, W S, Steinbach, J P, Burger, M C
Published in Neuro-oncology (Charlottesville, Va.) (09.09.2021)
Published in Neuro-oncology (Charlottesville, Va.) (09.09.2021)
Get full text
Journal Article
P12.04 Synergistic effects of combination therapy of CAR-NK cells and anti-PD-1 antibody result in high efficacy against advanced stage orthotopic glioblastoma grafts in a syngeneic mouse model and induce protective anti-tumor immunity in vivo
Strassheimer, F, Strecker, M I, Zhang, C, Mildenberger, I C, Harter, P N, Tonn, T, Steinbach, J P, Wels, W S, Burger, M C
Published in Neuro-oncology (Charlottesville, Va.) (06.09.2019)
Published in Neuro-oncology (Charlottesville, Va.) (06.09.2019)
Get full text
Journal Article
P04.21 Combination therapy of CAR-NK cells and anti-PD-1 antibody displays potent efficacy against late-stage Glioblastoma and induces protective antitumor immunity
Strassheimer, F, Zhang, C, Mildenberger, I C, Harter, P N, Tonn, T, Steinbach, J P, Wels, W S, Burger, M C
Published in Neuro-oncology (Charlottesville, Va.) (19.09.2018)
Published in Neuro-oncology (Charlottesville, Va.) (19.09.2018)
Get full text
Journal Article
P06.13 A novel local treatment approach? Targeted immunotherapy of glioblastoma via AAV-mediated gene transfer of checkpoint inhibitors through locally administered HER2-AAVs in combination with CAR-NK cells
Strecker, MI, Strassheimer, F, Reul, J, Harter, P N, Tonn, T, Steinbach, J P, Wels, W S, Buchholz, C J, Burger, M C
Published in Journal for immunotherapy of cancer (01.10.2020)
Published in Journal for immunotherapy of cancer (01.10.2020)
Get full text
Journal Article
P06.12 Combination therapy of CAR-NK-cells and anti-PD-1 antibody results in high efficacy against advanced-stage glioblastoma in a syngeneic mouse model and induces protective anti-tumor immunity in vivo
Strassheimer, F, Strecker, MI, Alekseeva, T, Macas, J, Demes, M C, Mildenberger, I C, Tonn, T, Wild, P J, Sevenich, L, Reiss, Y, Harter, P N, Plate, KH, Wels, W S, Steinbach, J P, Burger, M C
Published in Journal for immunotherapy of cancer (01.10.2020)
Published in Journal for immunotherapy of cancer (01.10.2020)
Get full text
Journal Article