Cellular function and molecular structure of ecto-nucleotidases
Zimmermann, Herbert, Zebisch, Matthias, Sträter, Norbert
Published in Purinergic signalling (01.09.2012)
Published in Purinergic signalling (01.09.2012)
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Insect-Derived Proline-Rich Antimicrobial Peptides Kill Bacteria by Inhibiting Bacterial Protein Translation at the 70S Ribosome
Krizsan, Andor, Volke, Daniela, Weinert, Stefanie, Straeter, Norbert, Knappe, Daniel, Hoffmann, Ralf
Published in Angewandte Chemie International Edition (03.11.2014)
Published in Angewandte Chemie International Edition (03.11.2014)
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Calcium-sensing receptor-mediated NLRP3 inflammasome response to calciprotein particles drives inflammation in rheumatoid arthritis
Jäger, Elisabeth, Murthy, Supriya, Schmidt, Caroline, Hahn, Magdalena, Strobel, Sarah, Peters, Anna, Stäubert, Claudia, Sungur, Pelin, Venus, Tom, Geisler, Mandy, Radusheva, Veselina, Raps, Stefanie, Rothe, Kathrin, Scholz, Roger, Jung, Sebastian, Wagner, Sylke, Pierer, Matthias, Seifert, Olga, Chang, Wenhan, Estrela-Lopis, Irina, Raulien, Nora, Krohn, Knut, Sträter, Norbert, Hoeppener, Stephanie, Schöneberg, Torsten, Rossol, Manuela, Wagner, Ulf
Published in Nature communications (25.08.2020)
Published in Nature communications (25.08.2020)
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Structural basis of the activation of PPARγ by the plasticizer metabolites MEHP and MINCH
Useini, Abibe, Engelberger, Felipe, Künze, Georg, Sträter, Norbert
Published in Environment international (01.03.2023)
Published in Environment international (01.03.2023)
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Discovery and Crystallographic Studies of Trisubstituted Piperazine Derivatives as Non-Covalent SARS-CoV‑2 Main Protease Inhibitors with High Target Specificity and Low Toxicity
Gao, Shenghua, Sylvester, Katharina, Song, Letian, Claff, Tobias, Jing, Lanlan, Woodson, Molly, Weiße, Renato H., Cheng, Yusen, Schäkel, Laura, Petry, Marvin, Gütschow, Michael, Schiedel, Anke C., Sträter, Norbert, Kang, Dongwei, Xu, Shujing, Toth, Karoly, Tavis, John, Tollefson, Ann E., Müller, Christa E., Liu, Xinyong, Zhan, Peng
Published in Journal of medicinal chemistry (13.10.2022)
Published in Journal of medicinal chemistry (13.10.2022)
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Analysis of double-emulsion droplets with ESI mass spectrometry for monitoring lipase-catalyzed ester hydrolysis at nanoliter scale
Heiligenthal, Laura, van der Loh, Marie, Polack, Matthias, Blaha, Maximilian E., Moschütz, Susanne, Keim, Antje, Sträter, Norbert, Belder, Detlev
Published in Analytical and bioanalytical chemistry (01.09.2022)
Published in Analytical and bioanalytical chemistry (01.09.2022)
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Structure and function of the metagenomic plastic-degrading polyester hydrolase PHL7 bound to its product
Richter, P Konstantin, Blázquez-Sánchez, Paula, Zhao, Ziyue, Engelberger, Felipe, Wiebeler, Christian, Künze, Georg, Frank, Ronny, Krinke, Dana, Frezzotti, Emanuele, Lihanova, Yuliia, Falkenstein, Patricia, Matysik, Jörg, Zimmermann, Wolfgang, Sträter, Norbert, Sonnendecker, Christian
Published in Nature communications (05.04.2023)
Published in Nature communications (05.04.2023)
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α,β-Methylene-ADP (AOPCP) Derivatives and Analogues: Development of Potent and Selective ecto-5′-Nucleotidase (CD73) Inhibitors
Bhattarai, Sanjay, Freundlieb, Marianne, Pippel, Jan, Meyer, Anne, Abdelrahman, Aliaa, Fiene, Amelie, Lee, Sang-Yong, Zimmermann, Herbert, Yegutkin, Gennady G, Sträter, Norbert, El-Tayeb, Ali, Müller, Christa E
Published in Journal of medicinal chemistry (13.08.2015)
Published in Journal of medicinal chemistry (13.08.2015)
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Journal Article
Discovery and Crystallographic Studies of Nonpeptidic Piperazine Derivatives as Covalent SARS-CoV‑2 Main Protease Inhibitors
Gao, Shenghua, Song, Letian, Claff, Tobias, Woodson, Molly, Sylvester, Katharina, Jing, Lanlan, Weiße, Renato H., Cheng, Yusen, Sträter, Norbert, Schäkel, Laura, Gütschow, Michael, Ye, Bing, Yang, Mianling, Zhang, Tao, Kang, Dongwei, Toth, Karoly, Tavis, John, Tollefson, Ann E., Müller, Christa E., Zhan, Peng, Liu, Xinyong
Published in Journal of medicinal chemistry (22.12.2022)
Published in Journal of medicinal chemistry (22.12.2022)
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Journal Article
2‑Substituted α,β-Methylene-ADP Derivatives: Potent Competitive Ecto-5′-nucleotidase (CD73) Inhibitors with Variable Binding Modes
Bhattarai, Sanjay, Pippel, Jan, Scaletti, Emma, Idris, Riham, Freundlieb, Marianne, Rolshoven, Georg, Renn, Christian, Lee, Sang-Yong, Abdelrahman, Aliaa, Zimmermann, Herbert, El-Tayeb, Ali, Müller, Christa E, Sträter, Norbert
Published in Journal of medicinal chemistry (26.03.2020)
Published in Journal of medicinal chemistry (26.03.2020)
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Journal Article
Discovery of AB680: A Potent and Selective Inhibitor of CD73
Lawson, Kenneth V, Kalisiak, Jaroslaw, Lindsey, Erick A, Newcomb, Eric T, Leleti, Manmohan Reddy, Debien, Laurent, Rosen, Brandon R, Miles, Dillon H, Sharif, Ehesan U, Jeffrey, Jenna L, Tan, Joanne B. L, Chen, Ada, Zhao, Sharon, Xu, Guifen, Fu, Lijuan, Jin, Lixia, Park, Tim W, Berry, Wade, Moschütz, Susanne, Scaletti, Emma, Sträter, Norbert, Walker, Nigel P, Young, Stephen W, Walters, Matthew J, Schindler, Uli, Powers, Jay P
Published in Journal of medicinal chemistry (22.10.2020)
Published in Journal of medicinal chemistry (22.10.2020)
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Journal Article
Design, Synthesis, and Biological Evaluation of Trisubstituted Piperazine Derivatives as Noncovalent Severe Acute Respiratory Syndrome Coronavirus 2 Main Protease Inhibitors with Improved Antiviral Activity and Favorable Druggability
Gao, Shenghua, Song, Letian, Sylvester, Katharina, Mercorelli, Beatrice, Loregian, Arianna, Toth, Karoly, Weiße, Renato H., Useini, Abibe, Sträter, Norbert, Yang, Mianling, Ye, Bing, Tollefson, Ann E., Müller, Christa E., Liu, Xinyong, Zhan, Peng
Published in Journal of medicinal chemistry (14.12.2023)
Published in Journal of medicinal chemistry (14.12.2023)
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Journal Article
Macrocyclic Azapeptide Nitriles: Structure-Based Discovery of Potent SARS-CoV‑2 Main Protease Inhibitors as Antiviral Drugs
Breidenbach, Julian, Voget, Rabea, Si, Yaoyao, Hingst, Alexandra, Claff, Tobias, Sylvester, Katharina, Wolf, Valentina, Krasniqi, Vesa, Useini, Abibe, Sträter, Norbert, Ogura, Yukino, Kawaguchi, Atsushi, Müller, Christa E., Gütschow, Michael
Published in Journal of medicinal chemistry (16.05.2024)
Published in Journal of medicinal chemistry (16.05.2024)
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Journal Article
Discovery of Potent and Selective Non-Nucleotide Small Molecule Inhibitors of CD73
Beatty, Joel W, Lindsey, Erick A, Thomas-Tran, Rhiannon, Debien, Laurent, Mandal, Debashis, Jeffrey, Jenna L, Tran, Anh T, Fournier, Jeremy, Jacob, Steven D, Yan, Xuelei, Drew, Samuel L, Ginn, Elaine, Chen, Ada, Pham, Amber T, Zhao, Sharon, Jin, Lixia, Young, Stephen W, Walker, Nigel P, Leleti, Manmohan Reddy, Moschütz, Susanne, Sträter, Norbert, Powers, Jay P, Lawson, Kenneth V
Published in Journal of medicinal chemistry (23.04.2020)
Published in Journal of medicinal chemistry (23.04.2020)
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Journal Article
Regulatory Function of Hexokinase 2 in Glucose Signaling in Saccharomyces cerevisiae
Kriegel, Thomas M., Kettner, Karina, Rödel, Gerhard, Sträter, Norbert
Published in The Journal of biological chemistry (05.08.2016)
Published in The Journal of biological chemistry (05.08.2016)
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Journal Article
Structure–Activity Relationship of 3‑Methylcytidine-5′-α,β-methylenediphosphates as CD73 Inhibitors
Scortichini, Mirko, Idris, Riham Mohammed, Moschütz, Susanne, Keim, Antje, Salmaso, Veronica, Dobelmann, Clemens, Oliva, Paola, Losenkova, Karolina, Irjala, Heikki, Vaittinen, Samuli, Sandholm, Jouko, Yegutkin, Gennady G, Sträter, Norbert, Junker, Anna, Müller, Christa E, Jacobson, Kenneth A
Published in Journal of medicinal chemistry (10.02.2022)
Published in Journal of medicinal chemistry (10.02.2022)
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Journal Article
Substrate binding modes of purine and pyrimidine nucleotides to human ecto-5′-nucleotidase (CD73) and inhibition by their bisphosphonic acid derivatives
Scaletti, Emma, Huschmann, Franziska U., Mueller, Uwe, Weiss, Manfred S., Sträter, Norbert
Published in Purinergic signalling (01.12.2021)
Published in Purinergic signalling (01.12.2021)
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