A coiled-coil masking domain for selective activation of therapeutic antibodies
Trang, Vivian H, Zhang, Xinqun, Yumul, Roma C, Zeng, Weiping, Stone, Ivan J, Wo, Serena W, Dominguez, Melissa M, Cochran, Julia H, Simmons, Jessica K, Ryan, Maureen C, Lyon, Robert P, Senter, Peter D, Levengood, Matthew R
Published in Nature biotechnology (01.07.2019)
Published in Nature biotechnology (01.07.2019)
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Optimization of a PEGylated Glucuronide-Monomethylauristatin E Linker for Antibody-Drug Conjugates
Burke, Patrick J, Hamilton, Joseph Z, Jeffrey, Scott C, Hunter, Joshua H, Doronina, Svetlana O, Okeley, Nicole M, Miyamoto, Jamie B, Anderson, Martha E, Stone, Ivan J, Ulrich, Michelle L, Simmons, Jessica K, McKinney, Erica E, Senter, Peter D, Lyon, Robert P
Published in Molecular cancer therapeutics (01.01.2017)
Published in Molecular cancer therapeutics (01.01.2017)
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Development of Novel Quaternary Ammonium Linkers for Antibody-Drug Conjugates
Burke, Patrick J, Hamilton, Joseph Z, Pires, Thomas A, Setter, Jocelyn R, Hunter, Joshua H, Cochran, Julia H, Waight, Andrew B, Gordon, Kristine A, Toki, Brian E, Emmerton, Kim K, Zeng, Weiping, Stone, Ivan J, Senter, Peter D, Lyon, Robert P, Jeffrey, Scott C
Published in Molecular cancer therapeutics (01.05.2016)
Published in Molecular cancer therapeutics (01.05.2016)
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Potent Anticarcinoma Activity of the Humanized Anti-CD70 Antibody h1F6 Conjugated to the Tubulin Inhibitor Auristatin via an Uncleavable Linker
OFLAZOGLU, Ezogelin, STONE, Ivan J, GORDON, Kristine, WOOD, Christopher G, REPASKY, Elizabeth A, GREWAL, Iqbal S, LAW, Che-Leung, GERBERA, Hans-Peter
Published in Clinical cancer research (01.10.2008)
Published in Clinical cancer research (01.10.2008)
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Macrophages contribute to the antitumor activity of the anti-CD30 antibody SGN-30
Oflazoglu, Ezogelin, Stone, Ivan J., Gordon, Kristine A., Grewal, Iqbal S., van Rooijen, Nico, Law, Che-Leung, Gerber, Hans-Peter
Published in Blood (15.12.2007)
Published in Blood (15.12.2007)
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Tumor-Associated Macrophages Can Contribute to Antitumor Activity through FcγR-Mediated Processing of Antibody-Drug Conjugates
Li, Fu, Ulrich, Michelle, Jonas, Mechthild, Stone, Ivan J, Linares, Germein, Zhang, Xinqun, Westendorf, Lori, Benjamin, Dennis R, Law, Che-Leung
Published in Molecular cancer therapeutics (01.07.2017)
Published in Molecular cancer therapeutics (01.07.2017)
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A Potent Anti-CD70 Antibody–Drug Conjugate Combining a Dimeric Pyrrolobenzodiazepine Drug with Site-Specific Conjugation Technology
Jeffrey, Scott C, Burke, Patrick J, Lyon, Robert P, Meyer, David W, Sussman, Django, Anderson, Martha, Hunter, Joshua H, Leiske, Chris I, Miyamoto, Jamie B, Nicholas, Nicole D, Okeley, Nicole M, Sanderson, Russell J, Stone, Ivan J, Zeng, Weiping, Gregson, Stephen J, Masterson, Luke, Tiberghien, Arnaud C, Howard, Philip W, Thurston, David E, Law, Che-Leung, Senter, Peter D
Published in Bioconjugate chemistry (17.07.2013)
Published in Bioconjugate chemistry (17.07.2013)
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Journal Article
SGN-CD228A Is an Investigational CD228-Directed Antibody-Drug Conjugate with Potent Antitumor Activity across a Wide Spectrum of Preclinical Solid Tumor Models
Mazahreh, Rebecca, Mason, Marsha L, Gosink, John J, Olson, Devra J, Thurman, Robert, Hale, Christopher, Westendorf, Lori, Pires, Thomas A, Leiske, Christopher I, Carlson, Markus, Nguyen, Liem T, Cochran, Julia H, Okeley, Nicole M, Yumul, Roma, Jin, Steven, Stone, Ivan J, Sahetya, Disha, Nesterova, Albina, Allred, Sean, Hensley, Kelly M, Hu, Rachael, Lawrence, Robert, Lewis, Timothy S, Sandall, Sharsti
Published in Molecular cancer therapeutics (03.04.2023)
Published in Molecular cancer therapeutics (03.04.2023)
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Journal Article
Improving Antibody‐Tubulysin Conjugates through Linker Chemistry and Site‐Specific Conjugation
Hamilton, Joseph Z., Pires, Thomas A., Mitchell, Jamie A., Cochran, Julia H., Emmerton, Kim K., Zaval, Margo, Stone, Ivan J., Anderson, Martha E., Jin, Steven, Waight, Andrew B., Lyon, Robert P., Senter, Peter D., Jeffrey, Scott C., Burke, Patrick J.
Published in ChemMedChem (08.04.2021)
Published in ChemMedChem (08.04.2021)
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Characterization of SGN-CD123A, A Potent CD123-Directed Antibody-Drug Conjugate for Acute Myeloid Leukemia
Li, Fu, Sutherland, May Kung, Yu, Changpu, Walter, Roland B, Westendorf, Lori, Valliere-Douglass, John, Pan, Lucy, Cronkite, Ashley, Sussman, Django, Klussman, Kerry, Ulrich, Michelle, Anderson, Martha E, Stone, Ivan J, Zeng, Weiping, Jonas, Mechthild, Lewis, Timothy S, Goswami, Maitrayee, Wang, Sa A, Senter, Peter D, Law, Che-Leung, Feldman, Eric J, Benjamin, Dennis R
Published in Molecular cancer therapeutics (01.02.2018)
Published in Molecular cancer therapeutics (01.02.2018)
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Development and Properties of β-Glucuronide Linkers for Monoclonal Antibody−Drug Conjugates
Jeffrey, Scott C, Andreyka, Jamie B, Bernhardt, Starr X, Kissler, Kim M, Kline, Toni, Lenox, Joel S, Moser, Ruth F, Nguyen, Minh T, Okeley, Nicole M, Stone, Ivan J, Zhang, Xinqun, Senter, Peter D
Published in Bioconjugate chemistry (01.05.2006)
Published in Bioconjugate chemistry (01.05.2006)
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Journal Article
Abstract 750: Modular coiled-coil masking domains for tumor-specific antibody activation
Trang, Vivian H., Zhang, Xinqun, Dominguez, Melissa M., Zeng, Weiping, Cochran, Julia H., Stone, Ivan J., Senter, Peter D., Levengood, Matthew R.
Published in Cancer research (Chicago, Ill.) (01.07.2018)
Published in Cancer research (Chicago, Ill.) (01.07.2018)
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Journal Article
Front Cover: Improving Antibody‐Tubulysin Conjugates through Linker Chemistry and Site‐Specific Conjugation (ChemMedChem 7/2021)
Hamilton, Joseph Z., Pires, Thomas A., Mitchell, Jamie A., Cochran, Julia H., Emmerton, Kim K., Zaval, Margo, Stone, Ivan J., Anderson, Martha E., Jin, Steven, Waight, Andrew B., Lyon, Robert P., Senter, Peter D., Jeffrey, Scott C., Burke, Patrick J.
Published in ChemMedChem (08.04.2021)
Published in ChemMedChem (08.04.2021)
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Journal Article
Abstract 2647: SGN-CD70A, a novel and highly potent anti-CD70 ADC, induces double-strand DNA breaks and is active in models of MDR+ renal cell carcinoma (RCC) and non-Hodgkin lymphoma (NHL)
Sandall, Sharsti, Anderson, Martha, Jonas, Mechthild, Nesterova, Albina, Miyamoto, Jamie, Stone, Ivan J., Zeng, Weiping, Law, Che-Leung, Lewis, Timothy S.
Published in Cancer research (Chicago, Ill.) (01.10.2014)
Published in Cancer research (Chicago, Ill.) (01.10.2014)
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Preclinical Analysis of the Combined Activity of SGN-40, Anti-CD40 Monoclonal Antibody, with Rituximab in Non-Hodgkin Lymphoma
Lewis, Timothy S., McCormick, Renee S., McEarchern, Julie A., Kissler, Kim, Stone, Ivan J., Gerber, Hans-Peter, Drachman, Jonathan G., Grewal, Iqbal, Law, Che-Leung
Published in Blood (16.11.2008)
Published in Blood (16.11.2008)
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Constitutively active STAT6 predisposes toward a lymphoproliferative disorder
Kaplan, Mark H., Sehra, Sarita, Chang, Hua-Chen, O'Malley, John T., Mathur, Anubhav N., Bruns, Heather A.
Published in Blood (15.12.2007)
Published in Blood (15.12.2007)
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The Humanized Anti-CD40 Monoclonal Antibody, SGN-40, Potentiates Chemotherapy Regimens in NHL Xenograft Models Via Pro-Apoptotic Signaling
Lewis, Timothy S., McCormick, Renee S., Kissler, Kim, Stone, Ivan J., Jonas, Mechthild, Sutherland, May S.K., Gerber, Hans-Peter, Drachman, Jonathan G., Grewal, Iqbal S., Law, Che-Leung
Published in Blood (16.11.2007)
Published in Blood (16.11.2007)
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SEMICONDUCTOR WAFER FRONT SIDE PROTECTION
KRYWANCZYK TIMOTHY C, ABRAMS ALLAN D, BROUILLETTE DONALD W, DANAHER JOSEPH D, STONE IVAN J, WHALEN MATTHEW R, LAMOTHE RENE A
Year of Publication 13.03.2008
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Year of Publication 13.03.2008
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