Rational design of α-helical tandem repeat proteins with closed architectures
Doyle, Lindsey, Hallinan, Jazmine, Bolduc, Jill, Parmeggiani, Fabio, Baker, David, Stoddard, Barry L., Bradley, Philip
Published in Nature (London) (24.12.2015)
Published in Nature (London) (24.12.2015)
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Biocontainment of genetically modified organisms by synthetic protein design
Mandell, Daniel J., Lajoie, Marc J., Mee, Michael T., Takeuchi, Ryo, Kuznetsov, Gleb, Norville, Julie E., Gregg, Christopher J., Stoddard, Barry L., Church, George M.
Published in Nature (London) (05.02.2015)
Published in Nature (London) (05.02.2015)
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A synthetic sex ratio distortion system for the control of the human malaria mosquito
Galizi, Roberto, Doyle, Lindsey A., Menichelli, Miriam, Bernardini, Federica, Deredec, Anne, Burt, Austin, Stoddard, Barry L., Windbichler, Nikolai, Crisanti, Andrea
Published in Nature communications (10.06.2014)
Published in Nature communications (10.06.2014)
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Journal Article
De novo design of a fluorescence-activating β-barrel
Dou, Jiayi, Vorobieva, Anastassia A., Sheffler, William, Doyle, Lindsey A., Park, Hahnbeom, Bick, Matthew J., Mao, Binchen, Foight, Glenna W., Lee, Min Yen, Gagnon, Lauren A., Carter, Lauren, Sankaran, Banumathi, Ovchinnikov, Sergey, Marcos, Enrique, Huang, Po-Ssu, Vaughan, Joshua C., Stoddard, Barry L., Baker, David
Published in Nature (London) (27.09.2018)
Published in Nature (London) (27.09.2018)
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Identification and characterization of the WYL BrxR protein and its gene as separable regulatory elements of a BREX phage restriction system
Luyten, Yvette A, Hausman, Deanna E, Young, Juliana C, Doyle, Lindsey A, Higashi, Kerilyn M, Ubilla-Rodriguez, Natalia C, Lambert, Abigail R, Arroyo, Corina S, Forsberg, Kevin J, Morgan, Richard D, Stoddard, Barry L, Kaiser, Brett K
Published in Nucleic acids research (20.05.2022)
Published in Nucleic acids research (20.05.2022)
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The structural basis of mRNA recognition and binding by yeast pseudouridine synthase PUS1
Grünberg, Sebastian, Doyle, Lindsey A, Wolf, Eric J, Dai, Nan, Corrêa, Jr, Ivan R, Yigit, Erbay, Stoddard, Barry L
Published in PloS one (08.11.2023)
Published in PloS one (08.11.2023)
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Increased Diels-Alderase activity through backbone remodeling guided by Foldit players
Eiben, Christopher B, Siegel, Justin B, Bale, Jacob B, Cooper, Seth, Khatib, Firas, Shen, Betty W, Players, Foldit, Stoddard, Barry L, Popovic, Zoran, Baker, David
Published in Nature biotechnology (01.02.2012)
Published in Nature biotechnology (01.02.2012)
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Computational Design of an Enzyme Catalyst for a Stereoselective Bimolecular Diels-Alder Reaction
Siegel, Justin B, Zanghellini, Alexandre, Lovick, Helena M, Kiss, Gert, Lambert, Abigail R, St.Clair, Jennifer L, Gallaher, Jasmine L, Hilvert, Donald, Gelb, Michael H, Stoddard, Barry L, Houk, Kendall N, Michael, Forrest E, Baker, David
Published in Science (American Association for the Advancement of Science) (16.07.2010)
Published in Science (American Association for the Advancement of Science) (16.07.2010)
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Computational design of ligand-binding proteins with high affinity and selectivity
Tinberg, Christine E., Khare, Sagar D., Dou, Jiayi, Doyle, Lindsey, Nelson, Jorgen W., Schena, Alberto, Jankowski, Wojciech, Kalodimos, Charalampos G., Johnsson, Kai, Stoddard, Barry L., Baker, David
Published in Nature (London) (12.09.2013)
Published in Nature (London) (12.09.2013)
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Journal Article
Computational protein design enables a novel one-carbon assimilation pathway
Siegel, Justin B., Lee Smith, Amanda, Poust, Sean, Wargacki, Adam J., Bar-Even, Arren, Louw, Catherine, Shen, Betty W., Eiben, Christopher B., Tran, Huu M., Noor, Elad, Gallaher, Jasmine L., Bale, Jacob, Yoshikuni, Yasuo, Gelb, Michael H., Keasling, Jay D., Stoddard, Barry L., Lidstrom, Mary E., Baker, David
Published in Proceedings of the National Academy of Sciences - PNAS (24.03.2015)
Published in Proceedings of the National Academy of Sciences - PNAS (24.03.2015)
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A Computationally Designed Inhibitor of an Epstein-Barr Viral Bcl-2 Protein Induces Apoptosis in Infected Cells
Procko, Erik, Berguig, Geoffrey Y., Shen, Betty W., Song, Yifan, Frayo, Shani, Convertine, Anthony J., Margineantu, Daciana, Booth, Garrett, Correia, Bruno E., Cheng, Yuanhua, Schief, William R., Hockenbery, David M., Press, Oliver W., Stoddard, Barry L., Stayton, Patrick S., Baker, David
Published in Cell (19.06.2014)
Published in Cell (19.06.2014)
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Journal Article
Control of repeat-protein curvature by computational protein design
Park, Keunwan, Shen, Betty W, Parmeggiani, Fabio, Huang, Po-Ssu, Stoddard, Barry L, Baker, David
Published in Nature structural & molecular biology (01.02.2015)
Published in Nature structural & molecular biology (01.02.2015)
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