Synthesis and evaluation of alpha-(((2-haloethyl)amino)methyl)-2- nitro-1H-imidazole-1-ethanols as prodrugs of alpha-((1-aziridinyl)methyl)-2- nitro-1H-imidazole-1-ethanol (RSU-1069) and its analogues which are radiosensitizers and bioreductively activated cytotoxins
Jenkins, T.C., Naylor, M.A., O'Neill, P., Threadgill, M.D., Cole, S., Stratford, I.J., Adams, G.E., Fielden, E.M., Suto, M.J., Stier, M.A.
Published in Journal of medicinal chemistry (01.09.1990)
Published in Journal of medicinal chemistry (01.09.1990)
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Journal Article
Pharmacologic/pharmacokinetic evaluation of emesis induced by analogs of RSU 1069 and its control by antiemetic agents
Sebolt-Leopold, J.S., Vincent, P.W., Beningo, K.A., Elliott, W.L., Leopold, W.R., Heffner, T.G., Wiley, J.N., Stier, M.A., Suto, M.J.
Published in International journal of radiation oncology, biology, physics (1992)
Published in International journal of radiation oncology, biology, physics (1992)
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Conference Proceeding
A new class of analogues of the bifunctional radiosensitizer α-(1-aziridinylmethyl)-2-nitro-1H-imidazole-1-ethanol (RSU 1069) : the cycloalkylaziridines
SUTO, M. J, STIER, M. A, WERBEL, L. M, ARUNDEL-SUTO, C. M, LEOPOLD, W. R, ELLIOTT, W. E, SEBOLT-LEOPOLD, J. S
Published in Journal of medicinal chemistry (01.08.1991)
Published in Journal of medicinal chemistry (01.08.1991)
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