Utilizing the BiTE (bispecific T-cell engager) platform for immunotherapy of cancer
Stieglmaier, Julia, Benjamin, Jonathan, Nagorsen, Dirk
Published in Expert opinion on biological therapy (03.08.2015)
Published in Expert opinion on biological therapy (03.08.2015)
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Journal Article
International reference analysis of outcomes in adults with B-precursor Ph-negative relapsed/refractory acute lymphoblastic leukemia
Gökbuget, Nicola, Dombret, Hervè, Ribera, Jose-Maria, Fielding, Adele K, Advani, Anjali, Bassan, Renato, Chia, Victoria, Doubek, Michael, Giebel, Sebastian, Hoelzer, Dieter, Ifrah, Norbert, Katz, Aaron, Kelsh, Michael, Martinelli, Giovanni, Morgades, Mireia, O'Brien, Susan, Rowe, Jacob M, Stieglmaier, Julia, Wadleigh, Martha, Kantarjian, Hagop
Published in Haematologica (Roma) (01.12.2016)
Published in Haematologica (Roma) (01.12.2016)
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Journal Article
Minimal residual disease level predicts outcome in adults with Ph-negative B-precursor acute lymphoblastic leukemia
Gökbuget, Nicola, Dombret, Hervé, Giebel, Sebastian, Bruggemann, Monika, Doubek, Michael, Foà, Robin, Hoelzer, Dieter, Kim, Christopher, Martinelli, Giovanni, Parovichnikova, Elena, Rambaldi, Alessandro, Ribera, Josep-Maria, Schoonen, Marieke, Stieglmaier, Julia M., Zugmaier, Gerhard, Bassan, Renato
Published in Hematology (Luxembourg) (01.01.2019)
Published in Hematology (Luxembourg) (01.01.2019)
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Journal Article
Blinatumomab for minimal residual disease in adults with B-cell precursor acute lymphoblastic leukemia
Gökbuget, Nicola, Dombret, Hervé, Bonifacio, Massimiliano, Reichle, Albrecht, Graux, Carlos, Faul, Christoph, Diedrich, Helmut, Topp, Max S., Brüggemann, Monika, Horst, Heinz-August, Havelange, Violaine, Stieglmaier, Julia, Wessels, Hendrik, Haddad, Vincent, Benjamin, Jonathan E., Zugmaier, Gerhard, Nagorsen, Dirk, Bargou, Ralf C.
Published in Blood (05.04.2018)
Published in Blood (05.04.2018)
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Journal Article
Phase 2 study of the bispecific T-cell engager (BiTE) antibody blinatumomab in relapsed/refractory diffuse large B-cell lymphoma
Viardot, Andreas, Goebeler, Marie-Elisabeth, Hess, Georg, Neumann, Svenja, Pfreundschuh, Michael, Adrian, Nicole, Zettl, Florian, Libicher, Martin, Sayehli, Cyrus, Stieglmaier, Julia, Zhang, Alicia, Nagorsen, Dirk, Bargou, Ralf C.
Published in Blood (17.03.2016)
Published in Blood (17.03.2016)
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Journal Article
STEAP1–4 (Six-Transmembrane Epithelial Antigen of the Prostate 1–4) and Their Clinical Implications for Prostate Cancer
Xu, Michael, Evans, Latese, Bizzaro, Candice L, Quaglia, Fabio, Verrillo, Cecilia E, Li, Li, Stieglmaier, Julia, Schiewer, Matthew J, Languino, Lucia R, Kelly, William K
Published in Cancers (01.08.2022)
Published in Cancers (01.08.2022)
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A phase 1 study of AMG 509 in patients (pts) with metastatic castration-resistant prostate cancer (mCRPC)
Danila, Daniel Costin, Waterhouse, David Michael, Appleman, Leonard Joseph, Pook, David William, Matsubara, Nobuaki, Dorff, Tanya B., Lee, Jae-Lyun, Armstrong, Andrew J., Kim, Miso, Horvath, Lisa, Sumey, Christopher Joseph, Cooner, Freda, Salvati, Mark, Stieglmaier, Julia, Kelly, William Kevin
Published in Journal of clinical oncology (01.06.2022)
Published in Journal of clinical oncology (01.06.2022)
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Journal Article
AMG 509 (Xaluritamig), an Anti-STEAP1 XmAb 2+1 T-cell Redirecting Immune Therapy with Avidity-Dependent Activity against Prostate Cancer
Nolan-Stevaux, Olivier, Li, Cong, Liang, Lingming, Zhan, Jinghui, Estrada, Juan, Osgood, Tao, Li, Fei, Zhang, Hanzhi, Case, Ryan, Murawsky, Christopher M, Estes, Bram, Moore, Gregory L, Bernett, Matthew J, Muchhal, Umesh, Desjarlais, John R, Staley, Binnaz K, Stevens, Jennitte, Cooke, Keegan S, Aeffner, Famke, Thomas, Oliver, Stieglmaier, Julia, Lee, Jae-Lyun, Coxon, Angela, Bailis, Julie M
Published in Cancer discovery (12.01.2024)
Published in Cancer discovery (12.01.2024)
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Journal Article
Phase I study of AMG 509, a STEAP1 x CD3 T-cell recruiting XmAb 2+1 immune therapy, in patients with metastatic castration-resistant prostate cancer (mCRPC)
Kelly, William Kevin, Pook, David William, Appleman, Leonard Joseph, Waterhouse, David Michael, Horvath, Lisa, Edenfield, William Jeffery, Matsubara, Nobuaki, Danila, Daniel Costin, Aggarwal, Rahul Raj, Petrylak, Daniel Peter, Sartor, A. Oliver, Sumey, Christopher Joseph, Adra, Nabil, Armstrong, Andrew J., Cheng, Fu-Chih, Stieglmaier, Julia, Kouros-Mehr, Hosein, Dorff, Tanya B.
Published in Journal of clinical oncology (20.02.2021)
Published in Journal of clinical oncology (20.02.2021)
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Journal Article
Xaluritamig, a STEAP1 × CD3 XmAb 2+1 Immune Therapy for Metastatic Castration-Resistant Prostate Cancer: Results from Dose Exploration in a First-in-Human Study
Kelly, William K, Danila, Daniel C, Lin, Chia-Chi, Lee, Jae-Lyun, Matsubara, Nobuaki, Ward, Patrick J, Armstrong, Andrew J, Pook, David, Kim, Miso, Dorff, Tanya B, Fischer, Stefanie, Lin, Yung-Chang, Horvath, Lisa G, Sumey, Christopher, Yang, Zhao, Jurida, Gabor, Smith, Kristen M, Connarn, Jamie N, Penny, Hweixian L, Stieglmaier, Julia, Appleman, Leonard J
Published in Cancer discovery (12.01.2024)
Published in Cancer discovery (12.01.2024)
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Journal Article
Treatment of Relapsed/Refractory Diffuse Large B-Cell Lymphoma with the Bispecific T-Cell Engager (BiTE®) Antibody Construct Blinatumomab: Primary Analysis Results from an Open-Label, Phase 2 Study
Viardot, Andreas, Goebeler, Mariele, Hess, Georg, Neumann, Svenja, Pfreundschuh, Michael, Adrian, Nicole, Zettl, Florian, Libicher, Martin, Degenhard, Evelyn, Stieglmaier, Julia, Zhang, Alicia, Nagorsen, Dirk, Bargou, Ralf C.
Published in Blood (06.12.2014)
Published in Blood (06.12.2014)
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Journal Article
Long-Term Outcomes after Blinatumomab Treatment: Follow-up of a Phase 2 Study in Patients (Pts) with Minimal Residual Disease (MRD) Positive B-Cell Precursor Acute Lymphoblastic Leukemia (ALL)
Gökbuget, Nicola, Dombret, Hervé, Bonifacio, Massimiliano, Reichle, Albrecht, Graux, Carlos, Faul, Christoph, Diedrich, Helmut, Topp, Max S., Brüggemann, Monika, Horst, Heinz A., Stieglmaier, Julia, Wessels, Hendrik, Haddad, Vincent, Zugmaier, Gerhard, Nagorsen, Dirk, Bargou, Ralf C
Published in Blood (03.12.2015)
Published in Blood (03.12.2015)
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Journal Article
BLAST: A Confirmatory, Single-Arm, Phase 2 Study of Blinatumomab, a Bispecific T-Cell Engager (BiTE®) Antibody Construct, in Patients with Minimal Residual Disease B-Precursor Acute Lymphoblastic Leukemia (ALL)
Goekbuget, Nicola, Dombret, Hervé, Bonifacio, Massimiliano, Reichle, Albrecht, Graux, Carlos, Havelange, Violaine, Buss, Eike C., Faul, Christoph, Bruggemann, Monika, Ganser, Arnold, Stieglmaier, Julia, Wessels, Hendrik, Haddad, Vincent, Zugmaier, Gerhard, Nagorsen, Dirk, Bargou, Ralf C.
Published in Blood (06.12.2014)
Published in Blood (06.12.2014)
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Journal Article
Open-Label Phase 2 Study Of The Bispecific T-Cell Engager (BiTE®) Blinatumomab In Patients With Relapsed/Refractory Diffuse Large B-Cell Lymphoma
Viardot, Andreas, Goebeler, Mariele, Pfreundschuh, Michael, Adrian, Nicole, Libicher, Martin, Degenhard, Evelyn, Stieglmaier, Julia, Zhang, Alicia, Nagorsen, Dirk, Bargou, Ralf C.
Published in Blood (15.11.2013)
Published in Blood (15.11.2013)
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Journal Article
A novel CD19-directed recombinant bispecific antibody derivative with enhanced immune effector functions for human leukemic cells
Kellner, Christian, Bruenke, Joerg, Stieglmaier, Julia, Schwemmlein, Michael, Schwenkert, Michael, Singer, Heiko, Mentz, Kristin, Peipp, Matthias, Lang, Peter, Oduncu, Fuat, Stockmeyer, Bernhard, Fey, Georg H
Published in Journal of immunotherapy (1997) (01.11.2008)
Published in Journal of immunotherapy (1997) (01.11.2008)
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Journal Article
Selective induction of apoptosis in leukemic B-lymphoid cells by a CD19-specific TRAIL fusion protein
Stieglmaier, Julia, Bremer, Edwin, Kellner, Christian, Liebig, Tanja M., ten Cate, Bram, Peipp, Matthias, Schulze-Koops, Hendrik, Pfeiffer, Matthias, Bühring, Hans-Jörg, Greil, Johann, Oduncu, Fuat, Emmerich, Bertold, Fey, Georg H., Helfrich, Wijnand
Published in Cancer Immunology, Immunotherapy (01.02.2008)
Published in Cancer Immunology, Immunotherapy (01.02.2008)
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Journal Article
Superior Activity of Fusion Protein scFvRit:sFasL over Cotreatment with Rituximab and Fas Agonists
BREMER, Edwin, CATE, Bram Ten, HELFRICH, Wijnand, SAMPLONIUS, Douwe F, MUELLER, Nicole, WAJANT, Harald, STEL, Alja J, CHAMULEAU, Martine, VAN DE LOOSDRECHT, Arjan A, STIEGLMAIER, Julia, FEY, Georg H
Published in Cancer research (Chicago, Ill.) (15.01.2008)
Published in Cancer research (Chicago, Ill.) (15.01.2008)
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