Functional Analysis of the Chromosome 9p21.3 Coronary Artery Disease Risk Locus
Jarinova, Olga, Stewart, Alexandre F.R, Roberts, Robert, Wells, George, Lau, Paulina, Naing, Thet, Buerki, Christine, McLean, Bradley W, Cook, Richard C, Parker, Joel S, McPherson, Ruth
Published in Arteriosclerosis, thrombosis, and vascular biology (01.10.2009)
Published in Arteriosclerosis, thrombosis, and vascular biology (01.10.2009)
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Somatic Mutations in the Connexin 40 Gene (GJA5) in Atrial Fibrillation
Gollob, Michael H, Jones, Douglas L, Krahn, Andrew D, Danis, Lynne, Gong, Xiang-Qun, Shao, Qing, Liu, Xiaoqin, Veinot, John P, Tang, Anthony S.L, Stewart, Alexandre F.R, Tesson, Frederique, Klein, George J, Yee, Raymond, Skanes, Allan C, Guiraudon, Gerard M, Ebihara, Lisa, Bai, Donglin
Published in The New England journal of medicine (22.06.2006)
Published in The New England journal of medicine (22.06.2006)
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Gene Dosage of the Common Variant 9p21 Predicts Severity of Coronary Artery Disease
Dandona, Sonny, MD, Stewart, Alexandre F.R., PhD, Chen, Li, MSc, Williams, Kathryn, MS, So, Derek, MD, O'Brien, Ed, MD, Glover, Christopher, MD, LeMay, Michel, MD, Assogba, Olivia, BA, Vo, Lan, MSc, Wang, Yan Qing, BS, Labinaz, Marino, MD, Wells, George A., PhD, McPherson, Ruth, MD, PhD, Roberts, Robert, MD
Published in Journal of the American College of Cardiology (03.08.2010)
Published in Journal of the American College of Cardiology (03.08.2010)
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A Genome-Wide Association Study for Coronary Artery Disease Identifies a Novel Susceptibility Locus in the Major Histocompatibility Complex
Davies, Robert W, Wells, George A, Stewart, Alexandre F.R, Erdmann, Jeanette, Shah, Svati H, Ferguson, Jane F, Hall, Alistair S, Anand, Sonia S, Burnett, Mary S, Epstein, Stephen E, Dandona, Sonny, Chen, Li, Nahrstaedt, Janja, Loley, Christina, König, Inke R, Kraus, William E, Granger, Christopher B, Engert, James C, Hengstenberg, Christian, Wichmann, H.-Erich, Schreiber, Stefan, Tang, W.H Wilson, Ellis, Stephen G, Rader, Daniel J, Hazen, Stanley L, Reilly, Muredach P, Samani, Nilesh J, Schunkert, Heribert, Roberts, Robert, McPherson, Ruth
Published in Circulation. Cardiovascular genetics (01.04.2012)
Published in Circulation. Cardiovascular genetics (01.04.2012)
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SPG7 Variant Escapes Phosphorylation-Regulated Processing by AFG3L2, Elevates Mitochondrial ROS, and Is Associated with Multiple Clinical Phenotypes
Almontashiri, Naif A.M., Chen, Hsiao-Huei, Mailloux, Ryan J., Tatsuta, Takashi, Teng, Allen C.T., Mahmoud, Ahmad B., Ho, Tiffany, Stewart, Nicolas A.S., Rippstein, Peter, Harper, Mary Ellen, Roberts, Robert, Willenborg, Christina, Erdmann, Jeanette, Pastore, Annalisa, McBride, Heidi M., Langer, Thomas, Stewart, Alexandre F.R.
Published in Cell reports (Cambridge) (08.05.2014)
Published in Cell reports (Cambridge) (08.05.2014)
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Angiotensin II and Stretch Activate NADPH Oxidase to Destabilize Cardiac Kv4.3 Channel mRNA
Zhou, Chaoming, Ziegler, Chandra, Birder, Lori A, Stewart, Alexandre F.R, Levitan, Edwin S
Published in Circulation research (28.04.2006)
Published in Circulation research (28.04.2006)
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Is atherosclerosis fundamental to human aging? Lessons from ancient mummies
Clarke, Emily M, Thompson, Randall C., MD, Allam, Adel H., MD, Wann, L. Samuel, MD, Lombardi, Guido P., PhD, Sutherland, M. Linda, MD, Sutherland, James D., MD, MS, Cox, Samantha L., MD, Soliman, Muhammad Al-Tohamy, PhD, Abd el-Maksoud, Gomaa, PhD, Badr, Ibrahem, PhD, Miyamoto, Michael I., MD, MBA, Frohlich, Bruno, PhD, Nur el-din, Abdel-Halim, PhD, Stewart, Alexandre F.R., PhD, Narula, Jagat, MD, PhD, Zink, Albert R., PhD, Finch, Caleb E., PhD, Michalik, David E., DO, Thomas, Gregory S., MD, MPH
Published in Journal of cardiology (01.05.2014)
Published in Journal of cardiology (01.05.2014)
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Journal Article
Genomics in coronary artery disease: Past, present and future
Dandona, Sonny, MD FRCPC, Stewart, Alexandre F.R., BScH MSc PhD, Roberts, Robert, MD MACC
Published in Canadian journal of cardiology (01.03.2010)
Published in Canadian journal of cardiology (01.03.2010)
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Comparative Genome-Wide Association Studies in Mice and Humans for Trimethylamine N-Oxide, a Proatherogenic Metabolite of Choline and L-Carnitine
Hartiala, Jaana, Bennett, Brian J, Tang, W.H Wilson, Wang, Zeneng, Stewart, Alexandre F.R, Roberts, Robert, McPherson, Ruth, Lusis, Aldons J, Hazen, Stanley L, Allayee, Hooman
Published in Arteriosclerosis, thrombosis, and vascular biology (01.06.2014)
Published in Arteriosclerosis, thrombosis, and vascular biology (01.06.2014)
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Clinical and Genetic Association of Serum Paraoxonase and Arylesterase Activities With Cardiovascular Risk
Tang, W.H Wilson, Hartiala, Jaana, Fan, Yiying, Wu, Yuping, Stewart, Alexandre F.R, Erdmann, Jeanette, Kathiresan, Sekar, Roberts, Robert, McPherson, Ruth, Allayee, Hooman, Hazen, Stanley L
Published in Arteriosclerosis, thrombosis, and vascular biology (01.11.2012)
Published in Arteriosclerosis, thrombosis, and vascular biology (01.11.2012)
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Ketamine's schizophrenia-like effects are prevented by targeting PTP1B
Qin, Zhaohong, Zhang, Li, Zasloff, Michael A., Stewart, Alexandre F.R., Chen, Hsiao-Huei
Published in Neurobiology of disease (01.07.2021)
Published in Neurobiology of disease (01.07.2021)
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Tyrosine phosphatase PTP1B impairs presynaptic NMDA receptor-mediated plasticity in a mouse model of Alzheimer's disease
Zhang, Li, Qin, Zhaohong, Sharmin, Fariba, Lin, Wei, Ricke, Konrad M., Zasloff, Michael A., Stewart, Alexandre F.R., Chen, Hsiao-Huei
Published in Neurobiology of disease (01.08.2021)
Published in Neurobiology of disease (01.08.2021)
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Chronic Stress Induces Anxiety via an Amygdalar Intracellular Cascade that Impairs Endocannabinoid Signaling
Qin, Zhaohong, Zhou, Xun, Pandey, Nihar R., Vecchiarelli, Haley A., Stewart, Chloe A., Zhang, Xia, Lagace, Diane C., Brunel, Jean Michel, Béïque, Jean-Claude, Stewart, Alexandre F.R., Hill, Matthew N., Chen, Hsiao-Huei
Published in Neuron (Cambridge, Mass.) (18.03.2015)
Published in Neuron (Cambridge, Mass.) (18.03.2015)
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Homocysteine and coronary heart disease: meta-analysis of MTHFR case-control studies, avoiding publication bias
Clarke, Robert, Bennett, Derrick A, Parish, Sarah, Verhoef, Petra, Dötsch-Klerk, Mariska, Lathrop, Mark, Xu, Peng, Nordestgaard, Børge G, Holm, Hilma, Hopewell, Jemma C, Saleheen, Danish, Tanaka, Toshihiro, Anand, Sonia S, Chambers, John C, Kleber, Marcus E, Ouwehand, Willem H, Yamada, Yoshiji, Elbers, Clara, Peters, Bas, Stewart, Alexandre F R, Reilly, Muredach M, Thorand, Barbara, Yusuf, Salim, Engert, James C, Assimes, Themistocles L, Kooner, Jaspal, Danesh, John, Watkins, Hugh, Samani, Nilesh J, Collins, Rory, Peto, Richard
Published in PLoS medicine (01.02.2012)
Published in PLoS medicine (01.02.2012)
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IRF2BP2 Reduces Macrophage Inflammation and Susceptibility to Atherosclerosis
Chen, Hsiao-Huei, Keyhanian, Kianoosh, Zhou, Xun, Vilmundarson, Ragnar O, Almontashiri, Naif A.M, Cruz, Shelly A, Pandey, Nihar R, Lerma Yap, Nida, Ho, Tiffany, Stewart, Chloe A, Huang, Hua, Hari, Aswin, Geoffrion, Michele, McPherson, Ruth, Rayner, Katey J, Stewart, Alexandre F.R
Published in Circulation research (25.09.2015)
Published in Circulation research (25.09.2015)
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Systems Genetics Analysis of Genome-Wide Association Study Reveals Novel Associations Between Key Biological Processes and Coronary Artery Disease
Ghosh, Sujoy, Vivar, Juan, Nelson, Christopher P, Willenborg, Christina, Segrè, Ayellet V, Mäkinen, Ville-Petteri, Nikpay, Majid, Erdmann, Jeannette, Blankenberg, Stefan, O’Donnell, Christopher, März, Winfried, Laaksonen, Reijo, Stewart, Alexandre F.R, Epstein, Stephen E, Shah, Svati H, Granger, Christopher B, Hazen, Stanley L, Kathiresan, Sekar, Reilly, Muredach P, Yang, Xia, Quertermous, Thomas, Samani, Nilesh J, Schunkert, Heribert, Assimes, Themistocles L, McPherson, Ruth
Published in Arteriosclerosis, thrombosis, and vascular biology (01.07.2015)
Published in Arteriosclerosis, thrombosis, and vascular biology (01.07.2015)
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Rare copy number variants contribute to congenital left-sided heart disease
Hitz, Marc-Phillip, Lemieux-Perreault, Louis-Philippe, Marshall, Christian, Feroz-Zada, Yassamin, Davies, Robbie, Yang, Shi Wei, Lionel, Anath Christopher, D'Amours, Guylaine, Lemyre, Emmanuelle, Cullum, Rebecca, Bigras, Jean-Luc, Thibeault, Maryse, Chetaille, Philippe, Montpetit, Alexandre, Khairy, Paul, Overduin, Bert, Klaassen, Sabine, Hoodless, Pamela, Awadalla, Philip, Hussin, Julie, Idaghdour, Youssef, Nemer, Mona, Stewart, Alexandre F R, Boerkoel, Cornelius, Scherer, Stephen W, Richter, Andrea, Dubé, Marie-Pierre, Andelfinger, Gregor
Published in PLoS genetics (01.09.2012)
Published in PLoS genetics (01.09.2012)
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Adiposity significantly modifies genetic risk for dyslipidemia[S]
Cole, Christopher B., Nikpay, Majid, Lau, Paulina, Stewart, Alexandre F.R., Davies, Robert W., Wells, George A., Dent, Robert, McPherson, Ruth
Published in Journal of lipid research (01.11.2014)
Published in Journal of lipid research (01.11.2014)
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