Identification of novel mutational drivers reveals oncogene dependencies in multiple myeloma
Walker, Brian A., Mavrommatis, Konstantinos, Wardell, Christopher P., Ashby, T. Cody, Bauer, Michael, Davies, Faith E., Rosenthal, Adam, Wang, Hongwei, Qu, Pingping, Hoering, Antje, Samur, Mehmet, Towfic, Fadi, Ortiz, Maria, Flynt, Erin, Yu, Zhinuan, Yang, Zhihong, Rozelle, Dan, Obenauer, John, Trotter, Matthew, Auclair, Daniel, Keats, Jonathan, Bolli, Niccolo, Fulciniti, Mariateresa, Szalat, Raphael, Moreau, Philippe, Durie, Brian, Stewart, A. Keith, Goldschmidt, Hartmut, Raab, Marc S., Einsele, Hermann, Sonneveld, Pieter, San Miguel, Jesus, Lonial, Sagar, Jackson, Graham H., Anderson, Kenneth C., Avet-Loiseau, Herve, Munshi, Nikhil, Thakurta, Anjan, Morgan, Gareth J.
Published in Blood (09.08.2018)
Published in Blood (09.08.2018)
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How Thalidomide Works Against Cancer
Stewart, A. Keith
Published in Science (American Association for the Advancement of Science) (17.01.2014)
Published in Science (American Association for the Advancement of Science) (17.01.2014)
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Journal Article
Xbp1s-Negative Tumor B Cells and Pre-Plasmablasts Mediate Therapeutic Proteasome Inhibitor Resistance in Multiple Myeloma
Leung-Hagesteijn, Chungyee, Erdmann, Natalie, Cheung, Grace, Keats, Jonathan J., Stewart, A. Keith, Reece, Donna E., Chung, Kim Chan, Tiedemann, Rodger E.
Published in Cancer cell (09.09.2013)
Published in Cancer cell (09.09.2013)
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Cereblon expression is required for the antimyeloma activity of lenalidomide and pomalidomide
Zhu, Yuan Xiao, Braggio, Esteban, Shi, Chang-Xin, Bruins, Laura A., Schmidt, Jessica E., Van Wier, Scott, Chang, Xiu-Bao, Bjorklund, Chad C., Fonseca, Rafael, Bergsagel, P. Leif, Orlowski, Robert Z., Stewart, A. Keith
Published in Blood (03.11.2011)
Published in Blood (03.11.2011)
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Journal Article
International Myeloma Working Group Consensus Statement for the Management, Treatment, and Supportive Care of Patients With Myeloma Not Eligible for Standard Autologous Stem-Cell Transplantation
PALUMBO, Antonio, VINCENT RAJKUMAR, S, DIMOPOULOS, Meletios A, RICHARDSON, Paul G, CAVO, Michele, SPENCER, Andrew, KEITH STEWART, A, SHIMIZU, Kazuyuki, LONIAL, Sagar, SONNEVELD, Pieter, DURIE, Brian G. M, MOREAU, Philippe, SAN MIGUEL, Jesus F, ORLOWSKI, Robert Z, LAROCCA, Alessandra, NIESVIZKY, Ruben, MORGAN, Gareth, LANDGREN, Ola, HAJEK, Roman, EINSELE, Hermann, ANDERSON, Kenneth C
Published in Journal of clinical oncology (20.02.2014)
Published in Journal of clinical oncology (20.02.2014)
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Journal Article
A high-risk, Double-Hit, group of newly diagnosed myeloma identified by genomic analysis
Walker, Brian A., Mavrommatis, Konstantinos, Wardell, Christopher P., Ashby, T. Cody, Bauer, Michael, Davies, Faith, Rosenthal, Adam, Wang, Hongwei, Qu, Pingping, Hoering, Antje, Samur, Mehmet, Towfic, Fadi, Ortiz, Maria, Flynt, Erin, Yu, Zhinuan, Yang, Zhihong, Rozelle, Dan, Obenauer, John, Trotter, Matthew, Auclair, Daniel, Keats, Jonathan, Bolli, Niccolo, Fulciniti, Mariateresa, Szalat, Raphael, Moreau, Phillipe, Durie, Brian, Stewart, A. Keith, Goldschmidt, Hartmut, Raab, Marc S., Einsele, Hermann, Sonneveld, Pieter, San Miguel, Jesus, Lonial, Sagar, Jackson, Graham H., Anderson, Kenneth C., Avet-Loiseau, Herve, Munshi, Nikhil, Thakurta, Anjan, Morgan, Gareth
Published in Leukemia (01.01.2019)
Published in Leukemia (01.01.2019)
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Journal Article
A phase 2 study of single-agent carfilzomib (PX-171-003-A1) in patients with relapsed and refractory multiple myeloma
Siegel, David S., Martin, Thomas, Wang, Michael, Vij, Ravi, Jakubowiak, Andrzej J., Lonial, Sagar, Trudel, Suzanne, Kukreti, Vishal, Bahlis, Nizar, Alsina, Melissa, Chanan-Khan, Asher, Buadi, Francis, Reu, Frederic J., Somlo, George, Zonder, Jeffrey, Song, Kevin, Stewart, A. Keith, Stadtmauer, Edward, Kunkel, Lori, Wear, Sandra, Wong, Alvin F., Orlowski, Robert Z., Jagannath, Sundar
Published in Blood (04.10.2012)
Published in Blood (04.10.2012)
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Journal Article
Alu-dependent RNA editing of GLI1 promotes malignant regeneration in multiple myeloma
Lazzari, Elisa, Mondala, Phoebe K., Santos, Nathaniel Delos, Miller, Amber C., Pineda, Gabriel, Jiang, Qingfei, Leu, Heather, Ali, Shawn A., Ganesan, Anusha-Preethi, Wu, Christina N., Costello, Caitlin, Minden, Mark, Chiaramonte, Raffaella, Stewart, A. Keith, Crews, Leslie A., Jamieson, Catriona H. M.
Published in Nature communications (04.12.2017)
Published in Nature communications (04.12.2017)
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Journal Article
Geriatric assessment predicts survival and toxicities in elderly myeloma patients: an International Myeloma Working Group report
Palumbo, Antonio, Bringhen, Sara, Mateos, Maria-Victoria, Larocca, Alessandra, Facon, Thierry, Kumar, Shaji K., Offidani, Massimo, McCarthy, Philip, Evangelista, Andrea, Lonial, Sagar, Zweegman, Sonja, Musto, Pellegrino, Terpos, Evangelos, Belch, Andrew, Hajek, Roman, Ludwig, Heinz, Stewart, A. Keith, Moreau, Philippe, Anderson, Kenneth, Einsele, Hermann, Durie, Brian.G.M., Dimopoulos, Meletios A., Landgren, Ola, San Miguel, Jesus F., Richardson, Paul, Sonneveld, Pieter, Rajkumar, S. Vincent
Published in Blood (26.03.2015)
Published in Blood (26.03.2015)
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Journal Article
Carfilzomib, Lenalidomide, and Dexamethasone for Relapsed Multiple Myeloma
Stewart, A. Keith, Rajkumar, S. Vincent, Dimopoulos, Meletios A, Masszi, Tamás, Špička, Ivan, Oriol, Albert, Hájek, Roman, Rosiñol, Laura, Siegel, David S, Mihaylov, Georgi G, Goranova-Marinova, Vesselina, Rajnics, Péter, Suvorov, Aleksandr, Niesvizky, Ruben, Jakubowiak, Andrzej J, San-Miguel, Jesus F, Ludwig, Heinz, Wang, Michael, Maisnar, Vladimír, Minarik, Jiri, Bensinger, William I, Mateos, Maria-Victoria, Ben-Yehuda, Dina, Kukreti, Vishal, Zojwalla, Naseem, Tonda, Margaret E, Yang, Xinqun, Xing, Biao, Moreau, Philippe, Palumbo, Antonio
Published in The New England journal of medicine (08.01.2015)
Published in The New England journal of medicine (08.01.2015)
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Journal Article
Cyclophosphamide-bortezomib-dexamethasone (CyBorD) produces rapid and complete hematologic response in patients with AL amyloidosis
Mikhael, Joseph R., Schuster, Steven R., Jimenez-Zepeda, Victor H., Bello, Nancy, Spong, Jacy, Reeder, Craig B., Stewart, A. Keith, Bergsagel, P. Leif, Fonseca, Rafael
Published in Blood (10.05.2012)
Published in Blood (10.05.2012)
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Journal Article
Selective Inhibition of Nuclear Export With Oral Selinexor for Treatment of Relapsed or Refractory Multiple Myeloma
Vogl, Dan T, Dingli, David, Cornell, Robert Frank, Huff, Carol Ann, Jagannath, Sundar, Bhutani, Divaya, Zonder, Jeffrey, Baz, Rachid, Nooka, Ajay, Richter, Joshua, Cole, Craig, Vij, Ravi, Jakubowiak, Andrzej, Abonour, Rafat, Schiller, Gary, Parker, Terri L, Costa, Luciano J, Kaminetzky, David, Hoffman, James E, Yee, Andrew J, Chari, Ajai, Siegel, David, Fonseca, Rafael, Van Wier, Scott, Ahmann, Gregory, Lopez, Ilsel, Kauffman, Michael, Shacham, Sharon, Saint-Martin, Jean-Richard, Picklesimer, Carla D, Choe-Juliak, Cassandra, Stewart, A Keith
Published in Journal of clinical oncology (20.03.2018)
Published in Journal of clinical oncology (20.03.2018)
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Journal Article
Targeted sequencing of refractory myeloma reveals a high incidence of mutations in CRBN and Ras pathway genes
Kortüm, K.Martin, Mai, Elias K., Hanafiah, Nur H., Shi, Chang-Xi, Zhu, Yuan-Xiao, Bruins, Laura, Barrio, Santiago, Jedlowski, Patrick, Merz, Maximilian, Xu, Jing, Stewart, Robert A., Andrulis, Mindaugas, Jauch, Anna, Hillengass, Jens, Goldschmidt, Hartmut, Bergsagel, P.Leif, Braggio, Esteban, Stewart, A.Keith, Raab, Marc S.
Published in Blood (01.09.2016)
Published in Blood (01.09.2016)
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Journal Article
Consensus recommendations for risk stratification in multiple myeloma: report of the International Myeloma Workshop Consensus Panel 2
Munshi, Nikhil C., Anderson, Kenneth C., Bergsagel, P. Leif, Shaughnessy, John, Palumbo, Antonio, Durie, Brian, Fonseca, Rafael, Stewart, A. Keith, Harousseau, Jean-Luc, Dimopoulos, Meletios, Jagannath, Sundar, Hajek, Roman, Sezer, Orhan, Kyle, Robert, Sonneveld, Pieter, Cavo, Michele, Rajkumar, S. Vincent, San Miguel, Jesus, Crowley, John, Avet-Loiseau, Hervé
Published in Blood (05.05.2011)
Published in Blood (05.05.2011)
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Journal Article
Conference Proceeding
Randomized, multicenter, phase 2 study (EVOLUTION) of combinations of bortezomib, dexamethasone, cyclophosphamide, and lenalidomide in previously untreated multiple myeloma
Kumar, Shaji, Flinn, Ian, Richardson, Paul G., Hari, Parameswaran, Callander, Natalie, Noga, Stephen J., Stewart, A. Keith, Turturro, Francesco, Rifkin, Robert, Wolf, Jeffrey, Estevam, Jose, Mulligan, George, Shi, Hongliang, Webb, Iain J., Rajkumar, S. Vincent
Published in Blood (10.05.2012)
Published in Blood (10.05.2012)
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Journal Article
Genome-Wide Analysis Uncovers Novel Recurrent Alterations in Primary Central Nervous System Lymphomas
Braggio, Esteban, Van Wier, Scott, Ojha, Juhi, McPhail, Ellen, Asmann, Yan W, Egan, Jan, da Silva, Jackline Ayres, Schiff, David, Lopes, M Beatriz, Decker, Paul A, Valdez, Riccardo, Tibes, Raoul, Eckloff, Bruce, Witzig, Thomas E, Stewart, A Keith, Fonseca, Rafael, O'Neill, Brian Patrick
Published in Clinical cancer research (01.09.2015)
Published in Clinical cancer research (01.09.2015)
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Journal Article
Whole-genome sequencing of multiple myeloma from diagnosis to plasma cell leukemia reveals genomic initiating events, evolution, and clonal tides
Egan, Jan B., Shi, Chang-Xin, Tembe, Waibhav, Christoforides, Alexis, Kurdoglu, Ahmet, Sinari, Shripad, Middha, Sumit, Asmann, Yan, Schmidt, Jessica, Braggio, Esteban, Keats, Jonathan J., Fonseca, Rafael, Bergsagel, P. Leif, Craig, David W., Carpten, John D., Stewart, A. Keith
Published in Blood (02.08.2012)
Published in Blood (02.08.2012)
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Journal Article
Safety and tolerability of ixazomib, an oral proteasome inhibitor, in combination with lenalidomide and dexamethasone in patients with previously untreated multiple myeloma: an open-label phase 1/2 study
Kumar, Shaji K, Prof, Berdeja, Jesus G, MD, Niesvizky, Ruben, Prof, Lonial, Sagar, Prof, Laubach, Jacob P, MD, Hamadani, Mehdi, MD, Stewart, A Keith, Prof, Hari, Parameswaran, Prof, Roy, Vivek, MD, Vescio, Robert, MD, Kaufman, Jonathan L, MD, Berg, Deborah, MSN, Liao, Eileen, PhD, Di Bacco, Alessandra, PhD, Estevam, Jose, BSc, Gupta, Neeraj, PhD, Hui, Ai-Min, MD, Rajkumar, Vincent, Prof, Richardson, Paul G, Prof
Published in The lancet oncology (01.12.2014)
Published in The lancet oncology (01.12.2014)
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