Biologically active metabolites in drug discovery
Sun, Shaoyi, Wesolowski, Steven S.
Published in Bioorganic & medicinal chemistry letters (15.09.2021)
Published in Bioorganic & medicinal chemistry letters (15.09.2021)
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Journal Article
Synthesis of a Tetrahydronaphthyridine Spiropyrimidinetrione DNA Gyrase Inhibiting Antibacterial Agent - Differential Substitution at all Five Carbon Atoms of Pyridine
Basarab, Gregory S., Galullo, Vincent, DeGrace, Nancy, Hauck, Sheila, Joubran, Camil, Wesolowski, Steven S.
Published in Organic letters (19.12.2014)
Published in Organic letters (19.12.2014)
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Journal Article
Differential Pharmacology and Binding of mGlu2 Receptor Allosteric Modulators
O’Brien, Daniel E., Shaw, Douglas M., Cho, Hyekyung P., Cross, Alan J., Wesolowski, Steven S., Felts, Andrew S., Bergare, Jonas, Elmore, Charles S., Lindsley, Craig W., Niswender, Colleen M., Conn, P. Jeffrey
Published in Molecular pharmacology (01.05.2018)
Published in Molecular pharmacology (01.05.2018)
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Identification of CNS-Penetrant Aryl Sulfonamides as Isoform-Selective NaV1.6 Inhibitors with Efficacy in Mouse Models of Epilepsy
Focken, Thilo, Burford, Kristen, Grimwood, Michael E, Zenova, Alla, Andrez, Jean-Christophe, Gong, Wei, Wilson, Michael, Taron, Matt, Decker, Shannon, Lofstrand, Verner, Chowdhury, Sultan, Shuart, Noah, Lin, Sophia, Goodchild, Samuel J, Young, Clint, Soriano, Maegan, Tari, Parisa K, Waldbrook, Matthew, Nelkenbrecher, Karen, Kwan, Rainbow, Lindgren, Andrea, de Boer, Gina, Lee, Stephanie, Sojo, Luis, DeVita, Robert J, Cohen, Charles J, Wesolowski, Steven S, Johnson, J. P, Dehnhardt, Christoph M, Empfield, James R
Published in Journal of medicinal chemistry (14.11.2019)
Published in Journal of medicinal chemistry (14.11.2019)
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Journal Article
Novel inhibitors of As(III) S-adenosylmethionine methyltransferase (AS3MT) identified by virtual screening
Bürli, Roland W., Wei, Huijun, Ernst, Glen, Mariga, Abigail, Hardern, Ian M., Herlihy, Kara, Cross, Alan J., Wesolowski, Steven S., Chen, Hongming, McKay, Ronald D.G., Weinberger, Daniel R., Brandon, Nicholas J., Barrow, James C.
Published in Bioorganic & medicinal chemistry letters (15.10.2018)
Published in Bioorganic & medicinal chemistry letters (15.10.2018)
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Journal Article
Identification of CNS-Penetrant Aryl Sulfonamides as Isoform-Selective Na V 1.6 Inhibitors with Efficacy in Mouse Models of Epilepsy
Focken, Thilo, Burford, Kristen, Grimwood, Michael E, Zenova, Alla, Andrez, Jean-Christophe, Gong, Wei, Wilson, Michael, Taron, Matt, Decker, Shannon, Lofstrand, Verner, Chowdhury, Sultan, Shuart, Noah, Lin, Sophia, Goodchild, Samuel J, Young, Clint, Soriano, Maegan, Tari, Parisa K, Waldbrook, Matthew, Nelkenbrecher, Karen, Kwan, Rainbow, Lindgren, Andrea, de Boer, Gina, Lee, Stephanie, Sojo, Luis, DeVita, Robert J, Cohen, Charles J, Wesolowski, Steven S, Johnson, Jr, J P, Dehnhardt, Christoph M, Empfield, James R
Published in Journal of medicinal chemistry (14.11.2019)
Published in Journal of medicinal chemistry (14.11.2019)
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Journal Article
Differential Pharmacology and Binding of mGlu 2 Receptor Allosteric Modulators
O'Brien, Daniel E, Shaw, Douglas M, Cho, Hyekyung P, Cross, Alan J, Wesolowski, Steven S, Felts, Andrew S, Bergare, Jonas, Elmore, Charles S, Lindsley, Craig W, Niswender, Colleen M, Conn, P Jeffrey
Published in Molecular pharmacology (01.05.2018)
Published in Molecular pharmacology (01.05.2018)
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Journal Article
Quantification of the interrelationships of receptor pharmacologies within a tricyclic privileged structural scaffold through application of modified forward selection
Wood, Michael W., Wesolowski, Steven S., Widzowski, Daniel V., Cross, Alan J.
Published in Neuropharmacology (01.02.2014)
Published in Neuropharmacology (01.02.2014)
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Journal Article
Cytoplasmic Relocalization of TAR DNA-Binding Protein 43 Is Not Sufficient to Reproduce Cellular Pathologies Associated with ALS In vitro
Wobst, Heike J, Wesolowski, Steven S, Chadchankar, Jayashree, Delsing, Louise, Jacobsen, Steven, Mukherjee, Jayanta, Deeb, Tarek Z, Dunlop, John, Brandon, Nicholas J, Moss, Stephen J
Published in Frontiers in molecular neuroscience (24.02.2017)
Published in Frontiers in molecular neuroscience (24.02.2017)
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Journal Article
Electron Affinities of the DNA and RNA Bases
Wesolowski, Steven S, Leininger, Matthew L, Pentchev, Plamen N, Schaefer, Henry F
Published in Journal of the American Chemical Society (02.05.2001)
Published in Journal of the American Chemical Society (02.05.2001)
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Journal Article
Structures and Rotational Barriers of a Diiodobinorsnoutane: Energetic Preference for Gauche Conformation
Herres, Joseph P., Moran, Caitlin A., Forman, Mark A., Hall, James E., McCauley, John P., Pivonka, Don E., Wesolowski, Steven S.
Published in Journal of organic chemistry (05.08.2016)
Published in Journal of organic chemistry (05.08.2016)
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Journal Article
Synthetic Analogues of Huwentoxin-IV Spider Peptide With Altered Human NaV1.7/NaV1.6 Selectivity Ratios
Lopez, Ludivine, Montnach, Jérôme, Oliveira-Mendes, Barbara, Khakh, Kuldip, Thomas, Baptiste, Lin, Sophia, Caumes, Cécile, Wesolowski, Steven, Nicolas, Sébastien, Servent, Denis, Cohen, Charles, Béroud, Rémy, Benoit, Evelyne, De Waard, Michel
Published in Frontiers in cell and developmental biology (20.12.2021)
Published in Frontiers in cell and developmental biology (20.12.2021)
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Journal Article
Synthesis and SAR of aminothiazole fused benzazepines as selective dopamine D₂ partial agonists
Urbanek, Rebecca A, Xiong, Hui, Wu, Ye, Blackwell, William, Steelman, Gary, Rosamond, Jim, Wesolowski, Steven S, Campbell, James B, Zhang, Minli, Brockel, Becky, Widzowski, Daniel V
Published in Bioorganic & medicinal chemistry letters (15.01.2013)
Published in Bioorganic & medicinal chemistry letters (15.01.2013)
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Journal Article
Discovery and Preclinical Validation of [11C]AZ13153556, a Novel Probe for the Histamine Type 3 Receptor
Schou, Magnus, Varnäs, Katarina, Jureus, Anders, Ahlgren, Charlotte, Malmquist, Jonas, Häggkvist, Jenny, Tari, Lenke, Wesolowski, Steven S, Throner, Scott R, Brown, Dean G, Nilsson, Maria, Johnström, Peter, Finnema, Sjoerd J, Nakao, Ryuji, Amini, Nahid, Takano, Akihiro, Farde, Lars
Published in ACS chemical neuroscience (17.02.2016)
Published in ACS chemical neuroscience (17.02.2016)
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Journal Article
Developing dual functional allosteric modulators of GABA(A) receptors
Liu, Xiaodong F, Chang, Hui-Fang, Schmiesing, Richard Jon, Wesolowski, Steven S, Knappenberger, Katharine S, Arriza, Jeffrey L, Chapdelaine, Marc J
Published in Bioorganic & medicinal chemistry (01.12.2010)
Published in Bioorganic & medicinal chemistry (01.12.2010)
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Journal Article
Developing dual functional allosteric modulators of GABAA receptors
Liu, Xiaodong F., Chang, Hui-Fang, Schmiesing, Richard Jon, Wesolowski, Steven S., Knappenberger, Katharine S., Arriza, Jeffrey L., Chapdelaine, Marc J.
Published in Bioorganic & medicinal chemistry (01.12.2010)
Published in Bioorganic & medicinal chemistry (01.12.2010)
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