Effect of mutations at position E138 in HIV-1 reverse transcriptase on phenotypic susceptibility and virologic response to etravirine
Tambuyzer, Lotke, Nijs, Steven, Daems, Bjorn, Picchio, Gaston, Vingerhoets, Johan
Published in Journal of acquired immune deficiency syndromes (1999) (01.09.2011)
Published in Journal of acquired immune deficiency syndromes (1999) (01.09.2011)
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Resistance profile of etravirine: combined analysis of baseline genotypic and phenotypic data from the randomized, controlled Phase III clinical studies
VINGERHOETS, Johan, TAMBUYZER, Lotke, AZIJN, Hilde, HOOGSTOEL, Annemie, NIJS, Steven, PEETERS, Monika, DE BETHUNE, Marie-Pierre, DE SMEDT, Goedele, WOODFALL, Brian, PICCHIO, Gastón
Published in AIDS (London) (20.02.2010)
Published in AIDS (London) (20.02.2010)
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Connection Domain Mutations in HIV-1 Reverse Transcriptase Do Not Impact Etravirine Susceptibility and Virologic Responses to Etravirine-Containing Regimens
GUPTA, Soumi, VINGERHOETS, Johan, PETROPOULOS, Christos J, SCHAPIRO, Jonathan, WEI HUANG, PICCHIO, Gaston, FRANSEN, Signe, TAMBUYZER, Lotke, AZIJN, Hilde, FRANTZELL, Arne, PAREDES, Roger, COAKLEY, Eoin, NIJS, Steven, CLOTET, Bonaventura
Published in Antimicrobial Agents and Chemotherapy (01.06.2011)
Published in Antimicrobial Agents and Chemotherapy (01.06.2011)
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Pharmacokinetics of Etravirine Combined with Atazanavir/Ritonavir and a Nucleoside Reverse Transcriptase Inhibitor in Antiretroviral Treatment-Experienced, HIV-1-Infected Patients
Orrell, Catherine, Felizarta, Franco, Nell, André, Kakuda, Thomas N., Lavreys, Ludo, Nijs, Steven, Tambuyzer, Lotke, Van Solingen-Ristea, Rodica, Tomaka, Frank L.
Published in AIDS Research and Treatment (01.01.2015)
Published in AIDS Research and Treatment (01.01.2015)
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Evaluation of a mosaic HIV-1 vaccine in a multicentre, randomised, double-blind, placebo-controlled, phase 1/2a clinical trial (APPROACH) and in rhesus monkeys (NHP 13-19)
Barouch, Dan H, Tomaka, Frank L, Wegmann, Frank, Stieh, Daniel J, Alter, Galit, Robb, Merlin L, Michael, Nelson L, Peter, Lauren, Nkolola, Joseph P, Borducchi, Erica N, Chandrashekar, Abishek, Jetton, David, Stephenson, Kathryn E, Li, Wenjun, Korber, Bette, Tomaras, Georgia D, Montefiori, David C, Gray, Glenda, Frahm, Nicole, McElrath, M Juliana, Baden, Lindsey, Johnson, Jennifer, Hutter, Julia, Swann, Edith, Karita, Etienne, Kibuuka, Hannah, Mpendo, Juliet, Garrett, Nigel, Mngadi, Kathy, Chinyenze, Kundai, Priddy, Frances, Lazarus, Erica, Laher, Fatima, Nitayapan, Sorachai, Pitisuttithum, Punnee, Bart, Stephan, Campbell, Thomas, Feldman, Robert, Lucksinger, Gregg, Borremans, Caroline, Callewaert, Katleen, Roten, Raphaele, Sadoff, Jerald, Scheppler, Lorenz, Weijtens, Mo, Feddes-de Boer, Karin, van Manen, Daniëlle, Vreugdenhil, Jessica, Zahn, Roland, Lavreys, Ludo, Nijs, Steven, Tolboom, Jeroen, Hendriks, Jenny, Euler, Zelda, Pau, Maria G, Schuitemaker, Hanneke
Published in The Lancet (British edition) (21.07.2018)
Published in The Lancet (British edition) (21.07.2018)
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Safety and Immunogenicity of Ad26-Vectored HIV Vaccine With Mosaic Immunogens and a Novel Mosaic Envelope Protein in HIV-Uninfected Adults: A Phase 1/2a Study
Stieh, Daniel J, Barouch, Dan H, Comeaux, Christy, Sarnecki, Michal, Stephenson, Kathryn E, Walsh, Stephen R, Sawant, Sheetal, Heptinstall, Jack, Tomaras, Georgia D, Kublin, James G, McElrath, M Juliana, Cohen, Kristen W, De Rosa, Stephen C, Alter, Galit, Ferrari, Guido, Montefiori, David, Mann, Philipp, Nijs, Steven, Callewaert, Katleen, Goepfert, Paul A, Edupuganti, Srilatha, Karita, Etienne, Seaman, Michael S, Corey, Lawrence, Baden, Lindsey R, Pau, Maria G, Schuitemaker, Hanneke, Tomaka, Frank
Published in The Journal of infectious diseases (18.04.2023)
Published in The Journal of infectious diseases (18.04.2023)
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Mosaic HIV-1 vaccine regimen in southern African women (Imbokodo/HVTN 705/HPX2008): a randomised, double-blind, placebo-controlled, phase 2b trial
Gray, Glenda E, Mngadi, Kathryn, Lavreys, Ludo, Nijs, Steven, Gilbert, Peter B, Hural, John, Hyrien, Ollivier, Juraska, Michal, Luedtke, Alex, Mann, Philipp, McElrath, M Juliana, Odhiambo, Jackline A, Stieh, Daniel J, van Duijn, Janine, Takalani, Azwidihwi N, Willems, Wouter, Tapley, Asa, Tomaras, Georgia D, Van Hoof, Johan, Schuitemaker, Hanneke, Swann, Edith, Barouch, Dan H, Kublin, James G, Corey, Lawrence, Pau, Maria G, Buchbinder, Susan, Tomaka, Frank, Allagappen, Jon, Andriesen, Jessica, Ayres, Alison, Bekker, Linda-Gail, Borremans, Caroline, Brumskine, William, Chilengi, Roma, Dubula, Thozama, Garrett, Nigel, Gelderblom, Huub, Gill, Katherine, Hoosain, Zaheer, Hosseinipour, Mina, Hutter, Julia, Inambao, Mubiana, Innes, Craig, Kilembe, William, Kotze, Philippus, Kotze, Sheena, Laher, Fatima, Laszlo, Imre, Lazarus, Erica, Malahleha, Mookho, Mathebula, Matsontso, Matoga, Mitch, McClennen, Rachael, Mda, Pamela, Meerts, Peter, Naicker, Vimla, Naidoo, Logashvari, Philip, Tricia, Pitsi, Annah, Scheppler, Lorenz, Sopher, Carrie, Takuva, Simbarashe G., Viegas, Edna, Weijtens, Mo, Yuan, Olive
Published in The Lancet infectious diseases (01.11.2024)
Published in The Lancet infectious diseases (01.11.2024)
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Safety and immunogenicity of two heterologous HIV vaccine regimens in healthy, HIV-uninfected adults (TRAVERSE): a randomised, parallel-group, placebo-controlled, double-blind, phase 1/2a study
Baden, Lindsey R, Stieh, Daniel J, Sarnecki, Michal, Walsh, Stephen R, Tomaras, Georgia D, Kublin, James G, McElrath, M Juliana, Alter, Galit, Ferrari, Guido, Montefiori, David, Mann, Philipp, Nijs, Steven, Callewaert, Katleen, Goepfert, Paul, Edupuganti, Srilatha, Karita, Etienne, Langedijk, Johannes P, Wegmann, Frank, Corey, Lawrence, Pau, Maria G, Barouch, Dan H, Schuitemaker, Hanneke, Tomaka, Frank
Published in The lancet HIV (01.10.2020)
Published in The lancet HIV (01.10.2020)
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Pre-existing mutations in the rilpivirine Phase III trials ECHO and THRIVE: prevalence and impact on virological response
VINGERHOETS, Johan, RIMSKY, Laurence, VAN EYGEN, Veerle, NIJS, Steven, VANVEGGEL, Simon, BOVEN, Katia, PICCHIO, Gaston
Published in Antiviral therapy (01.01.2013)
Published in Antiviral therapy (01.01.2013)
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First-in-Human Randomized, Controlled Trial of Mosaic HIV-1 Immunogens Delivered via a Modified Vaccinia Ankara Vector
Baden, Lindsey R, Walsh, Stephen R, Seaman, Michael S, Cohen, Yehuda Z, Johnson, Jennifer A, Licona, J Humberto, Filter, Rachel D, Kleinjan, Jane A, Gothing, Jon A, Jennings, Julia, Peter, Lauren, Nkolola, Joseph, Abbink, Peter, Borducchi, Erica N, Kirilova, Marinela, Stephenson, Kathryn E, Pegu, Poonam, Eller, Michael A, Trinh, Hung V, Rao, Mangala, Ake, Julie A, Sarnecki, Michal, Nijs, Steven, Callewaert, Katleen, Schuitemaker, Hanneke, Hendriks, Jenny, Pau, Maria G, Tomaka, Frank, Korber, Bette T, Alter, Galit, Dolin, Raphael, Earl, Patricia L, Moss, Bernard, Michael, Nelson L, Robb, Merlin L, Barouch, Dan H
Published in The Journal of infectious diseases (13.07.2018)
Published in The Journal of infectious diseases (13.07.2018)
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Efficacy and safety of etravirine at week 96 in treatment-experienced HIV type-1-infected patients in the DUET-1 and DUET-2 trials
KATLAMA, Christine, CLOTET, Bonaventura, VHOODFALL, Brian, WITEK, James, MILLS, Anthony, TROTTIER, Benoit, MOLINA, Jean-Michel, GRINSZTEJN, Beatriz, TOWNER, William, HAUBRICH, Richard, NIJS, Steven, VINGERHOETS, Johan
Published in Antiviral therapy (01.01.2010)
Published in Antiviral therapy (01.01.2010)
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Immune correlates analysis of the Imbokodo (HVTN 705/HPX2008) efficacy trial of a mosaic HIV-1 vaccine regimen evaluated in Southern African people assigned female sex at birth: a two-phase case-control study
van Duijn, Janine, Dintwe, One, Heptinstall, Jack, Zhang, Lu, Mielke, Dieter, Khuzwayo, Sharon, Omar, Faatima Laher, Stanfield-Oakley, Sherry, Keyes, Taylor, Dunn, Brooke, Goodman, Derrick, Benkeser, David, Zou, Rodger, Hyrien, Ollivier, Giorgi, Elena E., Korber, Bette, Willems, Wouter, Swann, Edith, Kublin, James G., Pau, Maria G., Buchbinder, Susan, Tomaka, Frank, Nijs, Steven, Corey, Lawrence, Mngadi, Kathryn, Gray, Glenda E., Borducchi, Erica, Barouch, Dan H., Ferrari, Guido, De Rosa, Stephen C., Andersen-Nissen, Erica, Tomaras, Georgia D., Gilbert, Peter B., Allagappen, Jon, Andriesen, Jessica, Ayres, Alison, Baral, Saman, Bekker, Linda-Gail, Besethi, Asiphe, Borremans, Caroline, Braams, Esmee, Brackett, Caroline, Brumskine, William, Chilengi, Roma, Dubula, Thozama, Euler, Zelda, Everett, Sarah, Gelderblom, Huub, Goedhart, Dimitri, Goosmann, Erik, Grant, Shannon, Hands, Ellie, Haynes, Barton, Herringer, Bronwill, Hosseinipour, Mina, Hunidzarira, Portia, Inambao, Mubiana, Keyes, Taylor, Kilembe, William, Kotze, Philippus, Kotze, Sheena, Laszlo, Imre, Liao, Hua-Xin, Lin, Yong, Lu, Helen, Lucas, Judith, Malahleha, Mookho, McNair, Tara, Meerts, Peter, Mgaga, Zinhle, Mosito, Boitumelo, Moultrie, Andrew, Sarzotti-Kelsoe, Marcella, Mathebula, Matson Tso, Naidoo, Logashvari, Okkers, Cindy-Ann, Pasmans, Hella, Philip, Tricia, Ramos, Ornelia, Randhawa, April, Rohith, Shamiska, Rutten, Lucy, Sadoff, Jerald, Salinas, Gabriela, Scheppler, Lorenz, Schwedhelm, Katharine, Schuller, Nicolette, Sharak, Angelina, Stanfield-Oakley, Sherry, Sopher, Carrie, Tafatatha, Terence, Tang, Chan, Vandebosch, An, Viegas, Edna, Voillet, Valentin, Wegmann, Frank, Wilcox, Stephany, Williams, Anthony, Yu, Chenchen, Yu, Pei-Chun
Published in EBioMedicine (01.10.2024)
Published in EBioMedicine (01.10.2024)
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Assessment of etravirine resistance in HIV-1-infected paediatric patients using population and deep sequencing: final results of the PIANO study
Tambuyzer, Lotke, Thys, Kim, Hoogstoel, Annemie, Nijs, Steven, Tomaka, Frank, Opsomer, Magda, De Meyer, Sandra, Vingerhoets, Johan
Published in Antiviral therapy (01.01.2016)
Published in Antiviral therapy (01.01.2016)
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Pharmacokinetics and Pharmacokinetic/Pharmacodynamic Relationships of Etravirine in HIV-1-Infected, Treatment-Experienced Children and Adolescents in PIANO
Kakuda, Thomas N, Brochot, Anne, Green, Bruce, Nijs, Steven, Vis, Peter, Opsomer, Magda, Tomaka, Frank L, Hoetelmans, Richard M W
Published in Journal of clinical pharmacology (01.11.2016)
Published in Journal of clinical pharmacology (01.11.2016)
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Comparison of shortened mosaic HIV-1 vaccine schedules: a randomised, double-blind, placebo-controlled phase 1 trial (IPCAVD010/HPX1002) and a preclinical study in rhesus monkeys (NHP 17-22)
Stephenson, Kathryn E, Wegmann, Frank, Tomaka, Frank, Walsh, Stephen R, Tan, C Sabrina, Lavreys, Ludo, Ansel, Jessica L, Kanjilal, Diane G, Jaegle, Kate, Nkolola, Joseph P, Peter, Lauren, Fogel, Rachel, Bradshaw, Connor, Tyler, Anna, Makoni, Tatenda, Howe, Lisa, Quijada, Darla, Chandrashekar, Abishek, Bondzie, Esther A, Borducchi, Erica N, Yanosick, Katherine E, Hendriks, Jenny, Nijs, Steven, Truyers, Carla, Tolboom, Jeroen, Zahn, Roland C, Seaman, Michael S, Alter, Galit, Stieh, Daniel J, Pau, Maria Grazia, Schuitemaker, Hanneke, Barouch, Dan H
Published in The lancet HIV (01.06.2020)
Published in The lancet HIV (01.06.2020)
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Evaluation of a Mosaic HIV-1 Vaccine in a Randomized, Double-Blinded, Placebo-Controlled Phase I/IIa Clinical Trial and in Rhesus Monkeys
Barouch, Dan H., Tomaka, Frank L., Wegmann, Frank, Stieh, Daniel J., Alter, Galit, Robb, Merlin L., Michael, Nelson L., Peter, Lauren, Nkolola, Joseph P., Borducchi, Erica N., Chandrashekar, Abishek, Jetton, David, Stephenson, Kathryn E., Li, Wenjun, Korber, Bette, Tomaras, Georgia D., Montefiori, David C., Gray, Glenda, Frahm, Nicole, McElrath, M. Juliana, Baden, Lindsey, Johnson, Jennifer, Hutter, Julia, Swann, Edith, Karita, Etienne, Kibuuka, Hannah, Mpendo, Juliet, Garrett, Nigel, Mngadi, Kathy, Chinyenze, Kundai, Priddy, Frances, Lazarus, Erica, Laher, Fatima, Nitayapan, Sorachai, Pittisuttithum, Punnee, Bart, Stephan, Campbell, Thomas, Feldman, Robert, Lucksinger, Gregg, Borremans, Caroline, Callewaert, Katleen, Roten, Raphaele, Sadoff, Jerald, Scheppler, Lorenz, Weijtens, Mo, Feddes-de Boer, Karin, van Manen, Daniëlle, Vreugdenhil, Jessica, Zahn, Roland, Lavreys, Ludo, Nijs, Steven, Tolboom, Jeroen, Hendriks, Jenny, Euler, Zelda, Pau, Maria G., Schuitemaker, Hanneke
Published in The Lancet (British edition) (06.07.2018)
Published in The Lancet (British edition) (06.07.2018)
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Safety of etravirine in HIV-1/hepatitis B and/or C virus co-infected patients: pooled 96 week results from the Phase III DUET trials
Clotet, Bonaventura, Clumeck, Nathan, Katlama, Christine, Nijs, Steven, Witek, James
Published in Journal of antimicrobial chemotherapy (01.11.2010)
Published in Journal of antimicrobial chemotherapy (01.11.2010)
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Characterization of genotypic and phenotypic changes in HIV-1-infected patients with virologic failure on an etravirine-containing regimen in the DUET-1 and DUET-2 clinical studies
Tambuyzer, Lotke, Vingerhoets, Johan, Azijn, Hilde, Daems, Bjorn, Nijs, Steven, de Béthune, Marie-Pierre, Picchio, Gastón
Published in AIDS research and human retroviruses (01.11.2010)
Published in AIDS research and human retroviruses (01.11.2010)
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Pharmacokinetic interaction between etravirine or rilpivirine and telaprevir in healthy volunteers: A randomized, two-way crossover trial
Kakuda, Thomas N, Leopold, Lorant, Nijs, Steven, Vandevoorde, Ann, Crauwels, Herta M, Bertelsen, Kirk M, Stevens, Marita, Witek, James, van Delft, Yvon, Tomaka, Frank, Hoetelmans, Richard M W
Published in Journal of clinical pharmacology (01.05.2014)
Published in Journal of clinical pharmacology (01.05.2014)
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Similar predictions of etravirine sensitivity regardless of genotypic testing method used: comparison of available scoring systems
VINGERHOETS, Johan, NIJS, Steven, TAMBUYZER, Lotke, HOOGSTOEL, Annemie, ANDERSON, David, PICCHIO, Gaston
Published in Antiviral therapy (01.01.2012)
Published in Antiviral therapy (01.01.2012)
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