Common variants in MS4A4/MS4A6E, CD2uAP, CD33, and EPHA1 are associated with late-onset Alzheimer’s disease
Naj, Adam C, Jun, Gyungah, Beecham, Gary W, Wang, Li-San, Vardarajan, Badri Narayan, Buros, Jacqueline, Gallins, Paul J, Buxbaum, Joseph D, Jarvik, Gail P, Crane, Paul K, Larson, Eric B, Bird, Thomas D, Boeve, Bradley F, Graff-Radford, Neill R, De Jager, Philip L, Evans, Denis, Schneider, Julie A, Carrasquillo, Minerva M, Ertekin-Taner, Nilufer, Younkin, Steven G, Cruchaga, Carlos, Kauwe, John SK, Nowotny, Petra, Kramer, Patricia, Hardy, John, Huentelman, Matthew J, Myers, Amanda J, Barmada, Michael M, Demirci, F. Yesim, Baldwin, Clinton T, Green, Robert C, Rogaeva, Ekaterina, St George-Hyslop, Peter, Arnold, Steven E, Barber, Robert, Beach, Thomas, Bigio, Eileen H, Bowen, James D, Boxer, Adam, Burke, James R, Cairns, Nigel J, Carlson, Chris S, Carney, Regina M, Carroll, Steven L, Chui, Helena C, Clark, David G, Corneveaux, Jason, Cotman, Carl W, Cummings, Jeffrey L, DeCarli, Charles, DeKosky, Steven T, Diaz-Arrastia, Ramon, Dick, Malcolm, Dickson, Dennis W, Ellis, William G, Faber, Kelley M, Fallon, Kenneth B, Farlow, Martin R, Ferris, Steven, Frosch, Matthew P, Galasko, Douglas R, Ganguli, Mary, Gearing, Marla, Geschwind, Daniel H, Ghetti, Bernardino, Gilbert, John R, Gilman, Sid, Giordani, Bruno, Glass, Jonathan D, Growdon, John H, Hamilton, Ronald L, Harrell, Lindy E, Head, Elizabeth, Honig, Lawrence S, Hulette, Christine M, Hyman, Bradley T, Jicha, Gregory A, Jin, Lee-Way, Johnson, Nancy, Karlawish, Jason, Karydas, Anna, Kaye, Jeffrey A, Kim, Ronald, Koo, Edward H, Kowall, Neil W, Lah, James J, Levey, Allan I, Lieberman, Andrew P, Lopez, Oscar L, Mack, Wendy J, Marson, Daniel C, Martiniuk, Frank, Mash, Deborah C, Masliah, Eliezer, McCormick, Wayne C, McCurry, Susan M, McDavid, Andrew N, McKee, Ann C, Mesulam, Marsel, Miller, Bruce L
Published in Nature genetics (03.04.2011)
Published in Nature genetics (03.04.2011)
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Expression of β amyloid protein precursor mRNAs: Recognition of a novel alternatively spliced form and quantitation in alzheimer's disease using PCR
Golde, Todd E., Estus, Steven, Usiak, Marianne, Younkin, Linda H., Younkin, Steven G.
Published in Neuron (Cambridge, Mass.) (01.02.1990)
Published in Neuron (Cambridge, Mass.) (01.02.1990)
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Concordant Association of Insulin Degrading Enzyme Gene
Carrasquillo, Minerva M, Belbin, Olivia, Zou, Fanggeng, Allen, Mariet, Ertekin-Taner, Nilufer, Ansari, Morad, Wilcox, Samantha L, Kashino, Mariah R, Ma, Li, Younkin, Linda H, Younkin, Samuel G, Younkin, Curtis S, Dincman, Toros A, Howard, Melissa E, Howell, Chanley C, Stanton, Chloe M, Watson, Christopher M, Crump, Michael, Vitart, Veronique, Hayward, Caroline, Hastie, Nicholas D, Rudan, Igor, Campbell, Harry, Polasek, Ozren, Brown, Kristelle, Passmore, Peter, Craig, David, McGuinness, Bernadette, Todd, Stephen, Kehoe, Patrick G, Mann, David M, Smith, A. David, Beaumont, Helen, Warden, Donald, Holmes, Clive, Heun, Reinhard, Kölsch, Heike, Kalsheker, Noor, Pankratz, V. Shane, Dickson, Dennis W, Graff-Radford, Neill R, Petersen, Ronald C, Wright, Alan F, Younkin, Steven G, Morgan, Kevin
Published in PloS one (19.01.2010)
Published in PloS one (19.01.2010)
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Genetic Modification of the Phenotypes Produced by Amyloid Precursor Protein Overexpression in Transgenic Mice
Carlson, George A., Borchelt, David R., Dake, Angela, Turner, Sherry, Danielson, Valerie, Coffin, J. Douglas, Eckman, Chris, Meiners, James, Nilsen, Steven P., Younkin, Steven G., Hsiao, Karen K.
Published in Human molecular genetics (01.10.1997)
Published in Human molecular genetics (01.10.1997)
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P1‐058: Association of glyceraldehyde‐3‐phosphate dehydrogenase locus variant with late‐onset Alzheimer's disease
Allen, Mariet, Cox, Claire, Belbin, Olivia, Ma, Li, Bisceglio, Gina D., Wilcox, Samantha L., Howell, Chanley C., Hunter, Talisha A., Culley, Oliver, Walker, Louise P., Carrasquillo, Minerva M., Dickson, Dennis W., Petersen, Ronald C., Graff-Radford, Neill R., Younkin, Steven G., Ertekin-Taner, Nilufer
Published in Alzheimer's & dementia (01.07.2010)
Published in Alzheimer's & dementia (01.07.2010)
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O4‐01‐03: Genome‐Wide Association Study (GWAS) of plasma Aß levels in the dalmatian islands of Vis and korcula
Allen, Mariet, Ansari, Morad, Younkin, Linda, Hayward, Caroline, Vitart, Veronique, Campbell, Susan, Huffman, Jennifer, Morgan, Joanne, Polasek, Ozren, Hastie, Nicholas D., Rudan, Igor, Campbell, Harry, Younkin, Steven G., Wright, Alan
Published in Alzheimer's & dementia (01.07.2009)
Published in Alzheimer's & dementia (01.07.2009)
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P4‐128: Association of a missense cathepsin D (CTSD) SNP with risk of Alzheimer's disease
Burgess, Jeremy, Leissring, Malcolm A., Ma, Li, Younkin, Linda H., Reinstatler, Lael, Crook, Julia E., Pankratz, V. Shane, Dickson, Dennis W., Peterson, Ronald C., Graff‐Radford, Neill R., Younkin, Steven G., Ertekin‐Taner, Nilufer
Published in Alzheimer's & dementia (01.07.2009)
Published in Alzheimer's & dementia (01.07.2009)
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BRI2 (ITM2b) Inhibits A^b Deposition In Vivo
Kim, Jungsu, Miller, Victor M, Levites, Yona, West, Karen Jansen, Zwizinski, Craig W, Moore, Brenda D, Troendle, Fredrick J, Bann, Maralyssa, Verbeeck, Christophe, Price, Robert W, Smithson, Lisa, Sonoda, Leilani, Wagg, Kayleigh, Rangachari, Vijayaraghavan, Zou, Fanggeng, Younkin, Steven G, Graff-Radford, Neill, Dickson, Dennis, Rosenberry, Terrone, Golde, Todd E
Published in The Journal of neuroscience (04.06.2008)
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Published in The Journal of neuroscience (04.06.2008)
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Amyloid β protein (Aβ) removal by neuroglial cells in culture
Shaffer, Lillian M., Dority, Michael D., Gupta-Bansal, Rekha, Frederickson, Robert C.A., Younkin, Steven G., Brunden, Kurt R.
Published in Neurobiology of aging (01.09.1995)
Published in Neurobiology of aging (01.09.1995)
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Erratum: Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease
Harold, Denise, Abraham, Richard, Hollingworth, Paul, Sims, Rebecca, Gerrish, Amy, Hamshere, Marian L, Pahwa, Jaspreet Singh, Moskvina, Valentina, Dowzell, Kimberley, Williams, Amy, Jones, Nicola, Thomas, Charlene, Stretton, Alexandra, Morgan, Angharad R, Lovestone, Simon, Powell, John, Proitsi, Petroula, Lupton, Michelle K, Brayne, Carol, Rubinsztein, David C, Gill, Michael, Lawlor, Brian, Lynch, Aoibhinn, Morgan, Kevin, Brown, Kristelle S, Passmore, Peter A, Craig, David, McGuinness, Bernadette, Todd, Stephen, Holmes, Clive, Mann, David, Smith, A David, Love, Seth, Kehoe, Patrick G, Hardy, John, Mead, Simon, Fox, Nick, Rossor, Martin, Collinge, John, Maier, Wolfgang, Jessen, Frank, Schürmann, Britta, van den Bussche, Hendrik, Heuser, Isabella, Kornhuber, Johannes, Wiltfang, Jens, Dichgans, Martin, Frölich, Lutz, Hampel, Harald, Hüll, Michael, Rujescu, Dan, Goate, Alison M, Kauwe, John S K, Cruchaga, Carlos, Nowotny, Petra, Morris, John C, Mayo, Kevin, Sleegers, Kristel, Bettens, Karolien, Engelborghs, Sebastiaan, De Deyn, Peter P, Van Broeckhoven, Christine, Livingston, Gill, Bass, Nicholas J, Gurling, Hugh, McQuillin, Andrew, Gwilliam, Rhian, Deloukas, Panagiotis, Al-Chalabi, Ammar, Shaw, Christopher E, Tsolaki, Magda, Singleton, Andrew B, Guerreiro, Rita, Mühleisen, Thomas W, Nöthen, Markus M, Moebus, Susanne, Jöckel, Karl-Heinz, Klopp, Norman, Wichmann, H-Erich, Carrasquillo, Minerva M, Pankratz, V Shane, Younkin, Steven G, Holmans, Peter A, O'Donovan, Michael, Owen, Michael J, Williams, Julie
Published in Nature genetics (01.10.2009)
Published in Nature genetics (01.10.2009)
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Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease, and shows evidence for additional susceptibility genes
Harold, Denise, Abraham, Richard, Hollingworth, Paul, Sims, Rebecca, Gerrish, Amy, Hamshere, Marian, Singh Pahwa, Jaspreet, Moskvina, Valentina, Dowzell, Kimberley, Williams, Amy, Jones, Nicola, Thomas, Charlene, Stretton, Alexandra, Morgan, Angharad, Lovestone, Simon, Powell, John, Proitsi, Petroula, Lupton, Michelle K, Brayne, Carol, Rubinsztein, David C., Gill, Michael, Lawlor, Brian, Lynch, Aoibhinn, Morgan, Kevin, Brown, Kristelle, Passmore, Peter, Craig, David, McGuinness, Bernadette, Todd, Stephen, Holmes, Clive, Mann, David, Smith, A. David, Love, Seth, Kehoe, Patrick G., Hardy, John, Mead, Simon, Fox, Nick, Rossor, Martin, Collinge, John, Maier, Wolfgang, Jessen, Frank, Schürmann, Britta, van den Bussche, Hendrik, Heuser, Isabella, Kornhuber, Johannes, Wiltfang, Jens, Dichgans, Martin, Frölich, Lutz, Hampel, Harald, Hüll, Michael, Rujescu, Dan, Goate, Alison, Kauwe, John S.K., Cruchaga, Carlos, Nowotny, Petra, Morris, John C., Mayo, Kevin, Sleegers, Kristel, Bettens, Karolien, Engelborghs, Sebastiaan, De Deyn, Peter, van Broeckhoven, Christine, Livingston, Gill, Bass, Nicholas J., Gurling, Hugh, McQuillin, Andrew, Gwilliam, Rhian, Deloukas, Panagiotis, Al-Chalabi, Ammar, Shaw, Christopher E., Tsolaki, Magda, Singleton, Andrew, Guerreiro, Rita, Mühleisen, Thomas W., Nöthen, Markus M., Moebus, Susanne, Jöckel, Karl-Heinz, Klopp, Norman, Wichmann, H-Erich, Carrasquillo, Minerva M., Pankratz, V. Shane, Younkin, Steven G., Holmans, Peter, O'Donovan, Michael, Owen, Michael J., Williams, Julie
Published in Nature genetics (06.09.2009)
Published in Nature genetics (06.09.2009)
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Cyclooxygenase-2 inhibition improves amyloid-[beta]-mediated suppression of memory and synaptic plasticity
Kotilinek, Linda A, Westerman, Marcus A, Wang, Qinwen, Panizzon, Kimberly, Lim, Giselle P, Simonyi, Agnes, Lesne, Sylvain, Falinska, Agnieszka, Younkin, Linda H, Younkin, Steven G, Rowan, Michael, Cleary, James, Wallis, Roi Ann, Sun, Grace Y, Cole, Greg, Frautschy, Sally, Anwyl, Roger, Ashe, Karen H
Published in Brain (London, England : 1878) (01.03.2008)
Published in Brain (London, England : 1878) (01.03.2008)
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Association of a missense cathepsin D (CTSD) SNP with risk of Alzheimer's disease
Burgess, Jeremy, Leissring, Malcolm A, Ma, Li, Younkin, Linda H, Reinstatler, Lael, Crook, Julia E, Pankratz, V. Shane, Dickson, Dennis W, Peterson, Ronald C, Graff-Radford, Neill R, Younkin, Steven G, Ertekin-Taner, Nilufer
Published in Alzheimer's & dementia (2009)
Published in Alzheimer's & dementia (2009)
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P4‐130: Concordant association of functional IDE variant with IDE mRNA, Aß, and Alzheimer's disease
Belbin, Olivia, Carrasquillo, Minerva, Zou, Fanggeng, Allen, Mariet, Ertekin‐Taner, Nilufer, Brown, Kristelle, Passmore, Peter, Craig, David, McGuinness, Bernadette, Todd, Stephen, Kehoe, Patrick G., Mann, David M., Smith, A. David, Beaumont, Helen, Warden, Donald, Holmes, Clive, Heun, Reinhard, Kolsch, Heike, Pankratz, V. Shane, Dickson, Dennis W., Graff‐Radford, Neil, Peterson, Ronald C., Wright, Alan F., Younkin, Steven G., Morgan, Kevin
Published in Alzheimer's & dementia (01.07.2009)
Published in Alzheimer's & dementia (01.07.2009)
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O4‐01‐06: Genetic variation in PCDH11X is associated with susceptibility to late‐onset Alzheimer's disease
Carrasquillo, Minerva M., Zou, Fanggeng, Pankratz, V. Shane, Wilcox, Samantha L., Ma, Li, Walker, Louise P., Younkin, Samuel G., Younkin, Curtis S., Younkin, Linda H., Bisceglio, Gina D., Ertekin‐Taner, Nilufer, Crook, Julia E., Dickson, Dennis W., Petersen, Ronald C., Graff‐Radford, Neill R., Younkin, Steven G.
Published in Alzheimer's & dementia (01.07.2009)
Published in Alzheimer's & dementia (01.07.2009)
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Journal Article
BRI2 (ITM2b) Inhibits A{beta} Deposition In Vivo
Kim, Jungsu, Miller, Victor M, Levites, Yona, West, Karen Jansen, Zwizinski, Craig W, Moore, Brenda D, Troendle, Fredrick J, Bann, Maralyssa, Verbeeck, Christophe, Price, Robert W, Smithson, Lisa, Sonoda, Leilani, Wagg, Kayleigh, Rangachari, Vijayaraghavan, Zou, Fanggeng, Younkin, Steven G, Graff-Radford, Neill, Dickson, Dennis, Rosenberry, Terrone, Golde, Todd E
Published in The Journal of neuroscience (04.06.2008)
Published in The Journal of neuroscience (04.06.2008)
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Antisense‐Induced Reduction of Presenilin 1 Expression Selectively Increases the Production of Amyloid β42 in Transfected Cells
Refolo, Lawrence M., Eckman, Chris, Prada, Christian‐Mihail, Yager, Debora, Sambamurti, Kumar, Mehta, Nitin, Hardy, John, Younkin, Steven G.
Published in Journal of neurochemistry (01.12.1999)
Published in Journal of neurochemistry (01.12.1999)
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Brain Aβ amyloidosis in APPsw mice induces accumulation of presenilin-I and tau
TOMIDOKORO, Yasushi, HARIGAYA, Yasuo, MATSUBARA, Etsuro, IKEDA, Masaki, KAWARABAYASHI, Takeshi, SHIRAO, Tomoaki, ISHIGURO, Koichi, OKAMOTO, Koichi, YOUNKIN, Steven G, SHOJI, Mikio
Published in The Journal of pathology (01.08.2001)
Published in The Journal of pathology (01.08.2001)
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