Reversal of Obesity- and Diet-Induced Insulin Resistance with Salicylates or Targeted Disruption of Ikkβ
Yuan, Minsheng, Konstantopoulos, Nicky, Lee, Jongsoon, Hansen, Lone, Li, Zhi-Wei, Karin, Michael, Shoelson, Steven E.
Published in Science (American Association for the Advancement of Science) (31.08.2001)
Published in Science (American Association for the Advancement of Science) (31.08.2001)
Get full text
Journal Article
Crystal Structure of the Pleckstrin Homology-Phosphotyrosine Binding (PH-PTB) Targeting Region of Insulin Receptor Substrate 1
Dhe-Paganon, Sirano, Ottinger, Elizabeth A., Nolte, Robert T., Eck, Michael J., Shoelson, Steven E.
Published in Proceedings of the National Academy of Sciences - PNAS (20.07.1999)
Published in Proceedings of the National Academy of Sciences - PNAS (20.07.1999)
Get full text
Journal Article
Retinal not systemic oxidative and inflammatory stress correlated with VEGF expression in rodent models of insulin resistance and diabetes
Mima, Akira, Qi, Weier, Hiraoka-Yamomoto, Junko, Park, Kyoungmin, Matsumoto, Motonobu, Kitada, Munehiro, Li, Qian, Mizutani, Koji, Yu, Edward, Shimada, Takeshi, Lee, Jongsoon, Shoelson, Steven E, Jobin, Christian, Rask-Madsen, Christian, King, George L
Published in Investigative ophthalmology & visual science (19.12.2012)
Published in Investigative ophthalmology & visual science (19.12.2012)
Get full text
Journal Article
Muscle-specific inhibition of the classical nuclear factor-κB pathway is protective against diaphragmatic weakness in murine endotoxemia
Okazaki, Tatsuma, Liang, Feng, Li, Tong, Lemaire, Christian, Danialou, Gawiyou, Shoelson, Steven E, Petrof, Basil J
Published in Critical care medicine (01.07.2014)
Published in Critical care medicine (01.07.2014)
Get more information
Journal Article
Sustained NFκB inhibition improves insulin sensitivity but is detrimental to muscle health
Zhang, Ning, Valentine, Joseph M., Zhou, You, Li, Mengyao E., Zhang, Yiqiang, Bhattacharya, Arunabh, Walsh, Michael E., Fischer, Katherine E., Austad, Steven N., Osmulski, Pawel, Gaczynska, Maria, Shoelson, Steven E., Van Remmen, Holly, Chen, Hung I., Chen, Yidong, Liang, Hanyu, Musi, Nicolas
Published in Aging cell (01.08.2017)
Published in Aging cell (01.08.2017)
Get full text
Journal Article
NF-κB activation is required for the transition of pulmonary inflammation to muscle atrophy
Langen, Ramon C J, Haegens, Astrid, Vernooy, Juanita H J, Wouters, Emiel F M, de Winther, Menno P J, Carlsen, Harald, Steele, Chad, Shoelson, Steven E, Schols, Annemie M W J
Published in American journal of respiratory cell and molecular biology (01.09.2012)
Published in American journal of respiratory cell and molecular biology (01.09.2012)
Get full text
Journal Article
Targeting Inflammation Using Salsalate in Patients With Type 2 Diabetes: Effects on Flow-Mediated Dilation (TINSAL-FMD)
GOLDFINE, Allison B, STEWART BUCK, J, DESOUZA, Cyrus, FONSECA, Vivian, IDA CHEN, Yii-Der, SHOELSON, Steven E, JABLONSKI, Kathleen A, CREAGER, Mark A
Published in Diabetes care (01.12.2013)
Published in Diabetes care (01.12.2013)
Get full text
Journal Article
Multiple Binding Modes between HNF4α and the LXXLL Motifs of PGC-1α Lead to Full Activation
Rha, Geun Bae, Wu, Guangteng, Shoelson, Steven E., Chi, Young-In
Published in The Journal of biological chemistry (11.12.2009)
Published in The Journal of biological chemistry (11.12.2009)
Get full text
Journal Article
Effect of Targeting Inflammation With Salsalate: The TINSAL-CVD Randomized Clinical Trial on Progression of Coronary Plaque in Overweight and Obese Patients Using Statins
Hauser, Thomas H, Salastekar, Ninad, Schaefer, Ernst J, Desai, Tanvi, Goldfine, Harvey L, Fowler, Kristen M, Weber, Griffin M, Welty, Francine, Clouse, Melvin, Shoelson, Steven E, Goldfine, Allison B
Published in JAMA cardiology (01.07.2016)
Published in JAMA cardiology (01.07.2016)
Get more information
Journal Article
Prevention of fat-induced insulin resistance by salicylate
Kim, J K, Kim, Y J, Fillmore, J J, Chen, Y, Moore, I, Lee, J, Yuan, M, Li, Z W, Karin, M, Perret, P, Shoelson, S E, Shulman, G I
Published in The Journal of clinical investigation (01.08.2001)
Published in The Journal of clinical investigation (01.08.2001)
Get full text
Journal Article
NF-κB activation and polyubiquitin conjugation are required for pulmonary inflammation-induced diaphragm atrophy
Haegens, Astrid, Schols, Annemie M, Gorissen, Stefan H, van Essen, Anon L, Snepvangers, Frank, Gray, Douglas A, Shoelson, Steven E, Langen, Ramon C
Published in American journal of physiology. Lung cellular and molecular physiology (01.01.2012)
Published in American journal of physiology. Lung cellular and molecular physiology (01.01.2012)
Get full text
Journal Article
Response to comment on Goldfine et al. Targeting inflammation using salsalate in patients with type 2 diabetes: effects on flow-mediated dilation (TINSAL-FMD). Diabetes care 2013;36:4132-4139
Goldfine, Allison B, Jablonski, Kathleen A, Shoelson, Steven E, Creager, Mark A
Published in Diabetes care (01.05.2014)
Published in Diabetes care (01.05.2014)
Get full text
Journal Article
PPAR-γ is a major driver of the accumulation and phenotype of adipose tissue Treg cells
Cipolletta, Daniela, Feuerer, Markus, Li, Amy, Kamei, Nozomu, Lee, Jongsoon, Shoelson, Steven E., Benoist, Christophe, Mathis, Diane
Published in Nature (London) (28.06.2012)
Published in Nature (London) (28.06.2012)
Get full text
Journal Article
Hepatocyte-specific IKKβ expression aggravates atherosclerosis development in APOE3-Leiden mice
Wong, Man C, van Diepen, Janna A, Hu, Lihui, Guigas, Bruno, de Boer, Hetty C, van Puijvelde, Gijs H, Kuiper, Johan, van Zonneveld, Anton J, Shoelson, Steven E, Voshol, Peter J, Romijn, Johannes A, Havekes, Louis M, Tamsma, Jouke T, Rensen, Patrick C.N, Hiemstra, Pieter S, Berbée, Jimmy F.P
Published in Atherosclerosis (01.02.2012)
Published in Atherosclerosis (01.02.2012)
Get full text
Journal Article
Effects of the anti-inflammatory drug salsalate on bone turnover in type 2 diabetes mellitus
Rubin, Mishaela R., Goldfine, Allison B., McMahon, Donald J., Donovan, Daniel S., Cremers, Serge, Dworakowski, Elzbieta, Schaefer, Ernst J., Shoelson, Steven E., Silverberg, Shonni J.
Published in Endocrine (01.11.2015)
Published in Endocrine (01.11.2015)
Get full text
Journal Article
Dileucine-based sorting signals bind to the β chain of AP-1 at a site distinct and regulated differently from the tyrosine-based motif-binding site
Rapoport, Iris, Chen, Yu Chen, Cupers, Philippe, Shoelson, Steven E., Kirchhausen, Tomas
Published in The EMBO journal (15.04.1998)
Published in The EMBO journal (15.04.1998)
Get full text
Journal Article