Synthesis of Nucleoside Phosphate and Phosphonate Prodrugs
Pradere, Ugo, Garnier-Amblard, Ethel C, Coats, Steven J, Amblard, Franck, Schinazi, Raymond F
Published in Chemical reviews (24.09.2014)
Published in Chemical reviews (24.09.2014)
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Antibody-Drug Conjugates: Future Directions in Clinical and Translational Strategies to Improve the Therapeutic Index
Coats, Steven, Williams, Marna, Kebble, Benjamin, Dixit, Rakesh, Tseng, Leo, Yao, Nai-Shun, Tice, David A, Soria, Jean-Charles
Published in Clinical cancer research (15.09.2019)
Published in Clinical cancer research (15.09.2019)
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A Biparatopic HER2-Targeting Antibody-Drug Conjugate Induces Tumor Regression in Primary Models Refractory to or Ineligible for HER2-Targeted Therapy
Li, John Y., Perry, Samuel R., Muniz-Medina, Vanessa, Wang, Xinzhong, Wetzel, Leslie K., Rebelatto, Marlon C., Hinrichs, Mary Jane Masson, Bezabeh, Binyam Z., Fleming, Ryan L., Dimasi, Nazzareno, Feng, Hui, Toader, Dorin, Yuan, Andy Q., Xu, Lan, Lin, Jia, Gao, Changshou, Wu, Herren, Dixit, Rakesh, Osbourn, Jane K., Coats, Steven R.
Published in Cancer cell (11.01.2016)
Published in Cancer cell (11.01.2016)
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HIV nucleoside reverse transcriptase inhibitors
Amblard, Franck, Patel, Dharmeshkumar, Michailidis, Eleftherios, Coats, Steven J., Kasthuri, Mahesh, Biteau, Nicolas, Tber, Zahira, Ehteshami, Maryam, Schinazi, Raymond F.
Published in European journal of medicinal chemistry (05.10.2022)
Published in European journal of medicinal chemistry (05.10.2022)
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HER2-targeted antibody-drug conjugate induces host immunity against cancer stem cells
Xia, Leiming, Wen, Lu, Qin, You, Dobson, Hannah E., Zhang, Tao, Comer, Frank I., Hinrichs, Mary Jane, Oberst, Michael D., Coats, Steven R., Chang, Alfred E., Liu, Yuanyuan, Bao, Yangyi, Dai, Fu, Wicha, Max S., Li, Qiao
Published in Cell chemical biology (20.05.2021)
Published in Cell chemical biology (20.05.2021)
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Journal Article
A Biparatopic HER2-Targeting Antibody-Drug Conjugate Induces Tumor Regression in Primary Models Refractory to or Ineligible for HER2-Targeted Therapy
Li, John Y., Perry, Samuel R., Muniz-Medina, Vanessa, Wang, Xinzhong, Wetzel, Leslie K., Rebelatto, Marlon C., Masson Hinrichs, Mary Jane, Bezabeh, Binyam Z., Fleming, Ryan L., Dimasi, Nazzareno, Feng, Hui, Toader, Dorin, Yuan, Andy Q., Xu, Lan, Lin, Jia, Gao, Changshou, Wu, Herren, Dixit, Rakesh, Osbourn, Jane K., Coats, Steven R.
Published in Cancer cell (10.06.2019)
Published in Cancer cell (10.06.2019)
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Synthesis and antiviral evaluation of novel heteroarylpyrimidines analogs as HBV capsid effectors
Boucle, Sebastien, Lu, Xiao, Bassit, Leda, Ozturk, Tugba, Russell, Olivia Ollinger, Amblard, Franck, Coats, Steven J., Schinazi, Raymond F.
Published in Bioorganic & medicinal chemistry letters (15.02.2017)
Published in Bioorganic & medicinal chemistry letters (15.02.2017)
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Journal Article
Synthesis and anti-HCV activity of β-d-2′-deoxy-2′-α-chloro-2′-β-fluoro and β-d-2′-deoxy-2′-α-bromo-2′-β-fluoro nucleosides and their phosphoramidate prodrugs
Ovadia, Reuben, Khalil, Ahmed, Li, Hao, De Schutter, Coralie, Mengshetti, Seema, Zhou, Shaoman, Bassit, Leda, Coats, Steven J., Amblard, Franck, Schinazi, Raymond F.
Published in Bioorganic & medicinal chemistry (15.02.2019)
Published in Bioorganic & medicinal chemistry (15.02.2019)
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Journal Article
2′-Chloro,2′-fluoro Ribonucleotide Prodrugs with Potent Pan-genotypic Activity against Hepatitis C Virus Replication in Culture
Zhou, Shaoman, Mahmoud, Sawsan, Liu, Peng, Zhou, Longhu, Ehteshami, Maryam, Bassit, Leda, Tao, Sijia, Domaoal, Robert A, Sari, Ozkan, Schutter, Coralie De, Amiralaei, Sheida, Khalil, Ahmed, Ollinger Russell, Olivia, McBrayer, Tamara, Whitaker, Tony, Abou-Taleb, Nageh, Amblard, Franck, Coats, Steven J, Schinazi, Raymond F
Published in Journal of medicinal chemistry (13.07.2017)
Published in Journal of medicinal chemistry (13.07.2017)
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Synthesis of carbocyclic nucleoside analogs with five-membered heterocyclic nucleobases
Cho, Jong hyun, Coats, Steven J., Schinazi, Raymond F.
Published in Tetrahedron letters (03.06.2015)
Published in Tetrahedron letters (03.06.2015)
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Asymmetric Binding to NS5A by Daclatasvir (BMS-790052) and Analogs Suggests Two Novel Modes of HCV Inhibition
Nettles, James H, Stanton, Richard A, Broyde, Joshua, Amblard, Franck, Zhang, Hongwang, Zhou, Longhu, Shi, Junxing, McBrayer, Tamara R, Whitaker, Tony, Coats, Steven J, Kohler, James J, Schinazi, Raymond F
Published in Journal of medicinal chemistry (11.12.2014)
Published in Journal of medicinal chemistry (11.12.2014)
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Azetidines and spiro azetidines as novel P2 units in hepatitis C virus NS3 protease inhibitors
Bondada, Lavanya, Rondla, Ramu, Pradere, Ugo, Liu, Peng, Li, Chengwei, Bobeck, Drew, McBrayer, Tamara, Tharnish, Philip, Courcambeck, Jerome, Halfon, Philippe, Whitaker, Tony, Amblard, Franck, Coats, Steven J., Schinazi, Raymond F.
Published in Bioorganic & medicinal chemistry letters (01.12.2013)
Published in Bioorganic & medicinal chemistry letters (01.12.2013)
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Synthesis and anti-HCV activity of a series of β-d-2′-deoxy-2′-dibromo nucleosides and their corresponding phosphoramidate prodrugs
Chen, Zhe, Cox, Bryan D., Garnier-Amblard, Ethel C., McBrayer, Tamara R., Coats, Steven J., Schinazi, Raymond F., Amblard, Franck
Published in Bioorganic & medicinal chemistry letters (01.12.2017)
Published in Bioorganic & medicinal chemistry letters (01.12.2017)
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Journal Article
Synthesis and antiviral evaluation of 2′,2′,3′,3′-tetrafluoro nucleoside analogs
Sari, Ozkan, Bassit, Leda, Gavegnano, Christina, McBrayer, Tamara R., McCormick, Louise, Cox, Bryan, Coats, Steven J., Amblard, Franck, Schinazi, Raymond F.
Published in Tetrahedron letters (15.02.2017)
Published in Tetrahedron letters (15.02.2017)
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Journal Article
A Therapeutic Uricase with Reduced Immunogenicity Risk and Improved Development Properties
Nyborg, Andrew C, Ward, Chris, Zacco, Anna, Chacko, Benoy, Grinberg, Luba, Geoghegan, James C, Bean, Ryan, Wendeler, Michaela, Bartnik, Frank, O'Connor, Ellen, Gruia, Flaviu, Iyer, Vidyashankara, Feng, Hui, Roy, Varnika, Berge, Mark, Miner, Jeffrey N, Wilson, David M, Zhou, Dongmei, Nicholson, Simone, Wilker, Clynn, Wu, Chi Y, Wilson, Susan, Jermutus, Lutz, Wu, Herren, Owen, David A, Osbourn, Jane, Coats, Steven, Baca, Manuel
Published in PloS one (21.12.2016)
Published in PloS one (21.12.2016)
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Journal Article
Discovery of a Series of 2′-α-Fluoro,2′-β-bromo-ribonucleosides and Their Phosphoramidate Prodrugs as Potent Pan-Genotypic Inhibitors of Hepatitis C Virus
Mengshetti, Seema, Zhou, Longhu, Sari, Ozkan, De Schutter, Coralie, Zhang, Hongwang, Cho, Jong Hyun, Tao, Sijia, Bassit, Leda C, Verma, Kiran, Domaoal, Robert A, Ehteshami, Maryam, Jiang, Yong, Ovadia, Reuben, Kasthuri, Mahesh, Ollinger Russell, Olivia, McBrayer, Tamara, Whitaker, Tony, Pattassery, Judy, Pascual, Maria Luz, Uher, Lothar, Lin, Biing Y, Lee, Sam, Amblard, Franck, Coats, Steven J, Schinazi, Raymond F
Published in Journal of medicinal chemistry (28.02.2019)
Published in Journal of medicinal chemistry (28.02.2019)
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Journal Article
Dual IGF-I/II-Neutralizing Antibody MEDI-573 Potently Inhibits IGF Signaling and Tumor Growth
JIN GAO, CHESEBROUGH, Jon W, COATS, Steven, BOSSLET, Klaus, CHANG, Yong S, CARTLIDGE, Susan A, RICKETTS, Sally-Ann, INCOGNITO, Leonard, VELDMAN-JONES, Margaret, BLAKEY, David C, TABRIZI, Mohammad, JALLAL, Bahija, TRAIL, Pamela A
Published in Cancer research (Chicago, Ill.) (01.02.2011)
Published in Cancer research (Chicago, Ill.) (01.02.2011)
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