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Isoforms of RNA-Editing Enzyme ADAR1 Independently Control Nucleic Acid Sensor MDA5-Driven Autoimmunity and Multi-organ Development
Pestal, Kathleen, Funk, Cory C., Snyder, Jessica M., Price, Nathan D., Treuting, Piper M., Stetson, Daniel B.
Published in Immunity (Cambridge, Mass.) (17.11.2015)
Published in Immunity (Cambridge, Mass.) (17.11.2015)
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ABCC1 transporter exports the immunostimulatory cyclic dinucleotide cGAMP
Maltbaek, Joanna H., Cambier, Stephanie, Snyder, Jessica M., Stetson, Daniel B.
Published in Immunity (Cambridge, Mass.) (11.10.2022)
Published in Immunity (Cambridge, Mass.) (11.10.2022)
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Tight nuclear tethering of cGAS is essential for preventing autoreactivity
Volkman, Hannah E, Cambier, Stephanie, Gray, Elizabeth E, Stetson, Daniel B
Published in eLife (06.12.2019)
Published in eLife (06.12.2019)
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Autoimmunity Initiates in Nonhematopoietic Cells and Progresses via Lymphocytes in an Interferon-Dependent Autoimmune Disease
Gall, Alevtina, Treuting, Piper, Elkon, Keith B., Loo, Yueh-Ming, Gale, Michael, Barber, Glen N., Stetson, Daniel B.
Published in Immunity (Cambridge, Mass.) (27.01.2012)
Published in Immunity (Cambridge, Mass.) (27.01.2012)
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Protein kinase R and the integrated stress response drive immunopathology caused by mutations in the RNA deaminase ADAR1
Maurano, Megan, Snyder, Jessica M., Connelly, Caitlin, Henao-Mejia, Jorge, Sidrauski, Carmela, Stetson, Daniel B.
Published in Immunity (Cambridge, Mass.) (14.09.2021)
Published in Immunity (Cambridge, Mass.) (14.09.2021)
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Intracellular Nucleic Acid Detection in Autoimmunity
Crowl, John T, Gray, Elizabeth E, Pestal, Kathleen, Volkman, Hannah E, Stetson, Daniel B
Published in Annual review of immunology (26.04.2017)
Published in Annual review of immunology (26.04.2017)
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The SKIV2L RNA exosome limits activation of the RIG-I-like receptors
Eckard, Sterling C, Rice, Gillian I, Fabre, Alexandre, Badens, Catherine, Gray, Elizabeth E, Hartley, Jane L, Crow, Yanick J, Stetson, Daniel B
Published in Nature immunology (01.09.2014)
Published in Nature immunology (01.09.2014)
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Limiting Cholesterol Biosynthetic Flux Spontaneously Engages Type I IFN Signaling
York, Autumn G., Williams, Kevin J., Argus, Joseph P., Zhou, Quan D., Brar, Gurpreet, Vergnes, Laurent, Gray, Elizabeth E., Zhen, Anjie, Wu, Nicholas C., Yamada, Douglas H., Cunningham, Cameron R., Tarling, Elizabeth J., Wilks, Moses Q., Casero, David, Gray, David H., Yu, Amy K., Wang, Eric S., Brooks, David G., Sun, Ren, Kitchen, Scott G., Wu, Ting-Ting, Reue, Karen, Stetson, Daniel B., Bensinger, Steven J.
Published in Cell (17.12.2015)
Published in Cell (17.12.2015)
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Computational design of constitutively active cGAS
Dowling, Quinton M., Volkman, Hannah E., Gray, Elizabeth E., Ovchinnikov, Sergey, Cambier, Stephanie, Bera, Asim K., Sankaran, Banumathi, Johnson, Max R., Bick, Matthew J., Kang, Alex, Stetson, Daniel B., King, Neil P.
Published in Nature structural & molecular biology (01.01.2023)
Published in Nature structural & molecular biology (01.01.2023)
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New frontiers in the cGAS-STING intracellular DNA-sensing pathway
Dvorkin, Steve, Cambier, Stephanie, Volkman, Hannah E., Stetson, Daniel B.
Published in Immunity (Cambridge, Mass.) (09.04.2024)
Published in Immunity (Cambridge, Mass.) (09.04.2024)
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ADAR1 mutation causes ZBP1-dependent immunopathology
Hubbard, Nicholas W., Ames, Joshua M., Maurano, Megan, Chu, Lan H., Somfleth, Kim Y., Gokhale, Nandan S., Werner, Margo, Snyder, Jessica M., Lichauco, Katrina, Savan, Ram, Stetson, Daniel B., Oberst, Andrew
Published in Nature (London) (28.07.2022)
Published in Nature (London) (28.07.2022)
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