Metabolite extraction from suspension-cultured mammalian cells for global metabolite profiling
Sellick, Christopher A, Hansen, Rasmus, Stephens, Gill M, Goodacre, Royston, Dickson, Alan J
Published in Nature protocols (01.08.2011)
Published in Nature protocols (01.08.2011)
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Journal Article
Asymmetric Reduction of Activated Alkenes by Pentaerythritol Tetranitrate Reductase: Specificity and Control of Stereochemical Outcome by Reaction Optimisation
Fryszkowska, Anna, Toogood, Helen, Sakuma, Michiyo, Gardiner, John M., Stephens, Gill M., Scrutton, Nigel S.
Published in Advanced synthesis & catalysis (01.11.2009)
Published in Advanced synthesis & catalysis (01.11.2009)
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Journal Article
Structure-Based Insight into the Asymmetric Bioreduction of the CC Double Bond of α,β-Unsaturated Nitroalkenes by Pentaerythritol Tetranitrate Reductase
Toogood, Helen S., Fryszkowska, Anna, Hare, Victoria, Fisher, Karl, Roujeinikova, Anna, Leys, David, Gardiner, John M., Stephens, Gill M., Scrutton, Nigel S.
Published in Advanced synthesis & catalysis (17.11.2008)
Published in Advanced synthesis & catalysis (17.11.2008)
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Focused Directed Evolution of Pentaerythritol Tetranitrate Reductase by Using Automated Anaerobic Kinetic Screening of Site‐Saturated Libraries
Hulley, Martyn E, Toogood, Helen S, Fryszkowska, Anna, Mansell, David, Stephens, Gill M, Gardiner, John M, Scrutton, Nigel S
Published in Chembiochem : a European journal of chemical biology (22.11.2010)
Published in Chembiochem : a European journal of chemical biology (22.11.2010)
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Journal Article
Metabolite profiling of CHO cells: Molecular reflections of bioprocessing effectiveness
Sellick, Christopher A, Croxford, Alexandra S, Maqsood, Arfa R, Stephens, Gill M, Westerhoff, Hans V, Goodacre, Royston, Dickson, Alan J
Published in Biotechnology journal (01.09.2015)
Published in Biotechnology journal (01.09.2015)
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A Site-Saturated Mutagenesis Study of Pentaerythritol Tetranitrate Reductase Reveals that Residues 181 and 184 Influence Ligand Binding, Stereochemistry and Reactivity
Toogood, Helen S., Fryszkowska, Anna, Hulley, Martyn, Sakuma, Michiyo, Mansell, David, Stephens, Gill M., Gardiner, John M., Scrutton, Nigel S.
Published in Chembiochem : a European journal of chemical biology (21.03.2011)
Published in Chembiochem : a European journal of chemical biology (21.03.2011)
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Journal Article
The challenge of applying Raman spectroscopy to monitor recombinant antibody production
Ashton, Lorna, Xu, Yun, Brewster, Victoria L, Cowcher, David P, Sellick, Christopher A, Dickson, Alan J, Stephens, Gill M, Goodacre, Royston
Published in Analyst (London) (21.11.2013)
Published in Analyst (London) (21.11.2013)
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Rapid monitoring of recombinant antibody production by mammalian cell cultures using fourier transform infrared spectroscopy and chemometrics
Sellick, Christopher A, Hansen, Rasmus, Jarvis, Roger M, Maqsood, Arfa R, Stephens, Gill M, Dickson, Alan J, Goodacre, Royston
Published in Biotechnology and bioengineering (15.06.2010)
Published in Biotechnology and bioengineering (15.06.2010)
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Journal Article
Evaluation of extraction processes for intracellular metabolite profiling of mammalian cells: matching extraction approaches to cell type and metabolite targets
Sellick, Christopher A, Knight, David, Croxford, Alexandra S, Maqsood, Arfa R, Stephens, Gill M, Goodacre, Royston, Dickson, Alan J
Published in Metabolomics (01.09.2010)
Published in Metabolomics (01.09.2010)
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Journal Article
Rapid characterization of N‐linked glycans from secreted and gel‐purified monoclonal antibodies using MALDI‐ToF mass spectrometry
Hansen, Rasmus, Dickson, Alan J, Goodacre, Royston, Stephens, Gill M, Sellick, Christopher A
Published in Biotechnology and bioengineering (01.12.2010)
Published in Biotechnology and bioengineering (01.12.2010)
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Journal Article
Active site modifications in pentaerythritol tetranitrate reductase can lead to improved product enantiopurity, decreased by-product formation and altered stereochemical outcome in reactions with α,β-unsaturated nitroolefins
Fryszkowska, Anna, Toogood, Helen, Sakuma, Michiyo, Stephens, Gill M., Gardiner, John M., Scrutton, Nigel S.
Published in Catalysis science & technology (01.01.2011)
Published in Catalysis science & technology (01.01.2011)
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Journal Article
Asymmetric Reduction of Activated Alkenes by Pentaerythritol Tetranitrate Reductase: Specificity and Control of Stereochemical Outcome by Reaction Optimisation
Fryszkowska, Anna, Toogood, Helen, Sakuma, Michiyo, Gardiner, John M., Stephens, Gill M., Scrutton, Nigel S.
Published in Advanced synthesis & catalysis (01.11.2009)
Published in Advanced synthesis & catalysis (01.11.2009)
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Journal Article
Inside Cover: Focused Directed Evolution of Pentaerythritol Tetranitrate Reductase by Using Automated Anaerobic Kinetic Screening of Site-Saturated Libraries (ChemBioChem 17/2010)
Hulley, Martyn E., Toogood, Helen S., Fryszkowska, Anna, Mansell, David, Stephens, Gill M., Gardiner, John M., Scrutton, Nigel S.
Published in Chembiochem : a European journal of chemical biology (22.11.2010)
Published in Chembiochem : a European journal of chemical biology (22.11.2010)
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Journal Article