Prospecting for microbial α-N-acetylgalactosaminidases yields a new class of GH31 O-glycanase
Rahfeld, Peter, Wardman, Jacob F., Mehr, Kevin, Huff, Drew, Morgan-Lang, Connor, Chen, Hong-Ming, Hallam, Steven J., Withers, Stephen G.
Published in The Journal of biological chemistry (01.11.2019)
Published in The Journal of biological chemistry (01.11.2019)
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Journal Article
Systematic Screening of Synthetic Gene-Encoded Enzymes for Synthesis of Modified Glycosides
Armstrong, Zachary, Liu, Feng, Chen, Hong-Ming, Hallam, Steven J, Withers, Stephen G
Published in ACS catalysis (05.04.2019)
Published in ACS catalysis (05.04.2019)
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Journal Article
Lipid-mimicking phosphorus-based glycosidase inactivators as pharmacological chaperones for the treatment of Gaucher's disease
Scherer, Manuel, Santana, Andrés G, Robinson, Kyle, Zhou, Steven, Overkleeft, Hermen S, Clarke, Lorne, Withers, Stephen G
Published in Chemical science (Cambridge) (27.10.2021)
Published in Chemical science (Cambridge) (27.10.2021)
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Journal Article
Metagenomics reveals functional synergy and novel polysaccharide utilization loci in the Castor canadensis fecal microbiome
Armstrong, Zachary, Mewis, Keith, Liu, Feng, Morgan-Lang, Connor, Scofield, Melanie, Durno, Evan, Chen, Hong Ming, Mehr, Kevin, Withers, Stephen G., Hallam, Steven J.
Published in The ISME Journal (01.11.2018)
Published in The ISME Journal (01.11.2018)
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Journal Article
Vinyl Halide‐Modified Unsaturated Cyclitols are Mechanism‐Based Glycosidase Inhibitors
Danby, Phillip M., Jeong, Andrew, Sim, Lyann, Sweeney, Ryan P., Wardman, Jacob F., Karimi, Ryan, Geissner, Andreas, Worrall, Liam J., Reid, Jolene. P., Strynadka, Natalie C. J., Withers, Stephen G.
Published in Angewandte Chemie International Edition (15.05.2023)
Published in Angewandte Chemie International Edition (15.05.2023)
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Journal Article
Synthesis and glycosidase inhibition of 3,4,5-trihydroxypiperidines using a one-pot amination-cyclisation cascade reaction
Dangerfield, Emma M., Meijlink, Michael A., Hunt-Painter, Alex A., Nasseri, Seyed A., Withers, Stephen G., Stocker, Bridget L., Timmer, Mattie S.M.
Published in Carbohydrate research (01.09.2024)
Published in Carbohydrate research (01.09.2024)
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Journal Article
The pK a values of the catalytic residues in the retaining glycoside hydrolase T26H mutant of T4 lysozyme
Brockerman, Jacob A, Okon, Mark, Withers, Stephen G, McIntosh, Lawrence P
Published in Protein science (01.03.2019)
Published in Protein science (01.03.2019)
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Journal Article
Attenuation of Polysialic Acid Biosynthesis in Cells by the Small Molecule Inhibitor 8‑Keto-sialic acid
Hunter, Carmanah, Gao, Zhizeng, Chen, Hong-Ming, Thompson, Nicole, Wakarchuk, Warren, Nitz, Mark, Withers, Stephen G., Willis, Lisa M.
Published in ACS chemical biology (20.01.2023)
Published in ACS chemical biology (20.01.2023)
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Journal Article
Synthesis of lipophilic 1-deoxygalactonojirimycin derivatives as D-galactosidase inhibitors
Schitter, Georg, Scheucher, Elisabeth, Steiner, Andreas J, Stütz, Arnold E, Thonhofer, Martin, Tarling, Chris A, Withers, Stephen G, Wicki, Jacqueline, Fantur, Katrin, Paschke, Eduard, Mahuran, Don J, Rigat, Brigitte A, Tropak, Michael, Wrodnigg, Tanja M
Published in Beilstein journal of organic chemistry (01.03.2010)
Published in Beilstein journal of organic chemistry (01.03.2010)
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Journal Article
Expansion of the glycosynthase repertoire to produce defined manno-oligosaccharides
Jahn, Michael, Stoll, Dominik, Warren, R Antony J, Szabó, Lóránd, Singh, Pritpal, Gilbert, Harry J, Ducros, Valérie M A, Davies, Gideon J, Withers, Stephen G
Published in Chemical communications (Cambridge, England) (01.01.2003)
Published in Chemical communications (Cambridge, England) (01.01.2003)
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Journal Article
Ligand-Directed Chemistry on Glycoside Hydrolases - A Proof of Concept Study
Prasch, Herwig, Wolfsgruber, Andreas, Thonhofer, Martin, Culum, Andre, Mandl, Christoph, Weber, Patrick, Zuendel, Melanie, Nasseri, Seyed A., Gonzalez Santana, Andres, Tegl, Gregor, Nidetzky, Bernd, Gruber, Karl, Stuetz, Arnold E., Withers, Stephen G., Wrodnigg, Tanja M.
Published in Chembiochem : a European journal of chemical biology (01.12.2023)
Published in Chembiochem : a European journal of chemical biology (01.12.2023)
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Journal Article
Structure of human ST8SiaIII sialyltransferase provides insight into cell-surface polysialylation
Volkers, Gesa, Worrall, Liam J, Kwan, David H, Yu, Ching-Ching, Baumann, Lars, Lameignere, Emilie, Wasney, Gregory A, Scott, Nichollas E, Wakarchuk, Warren, Foster, Leonard J, Withers, Stephen G, Strynadka, Natalie C J
Published in Nature structural & molecular biology (01.08.2015)
Published in Nature structural & molecular biology (01.08.2015)
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Journal Article
Development of an active site titration reagent for α-amylases
Sweeney, Ryan P, Danby, Phillip M, Geissner, Andreas, Karimi, Ryan, Brask, Jesper, Withers, Stephen G
Published in Chemical science (Cambridge) (03.11.2020)
Published in Chemical science (Cambridge) (03.11.2020)
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Journal Article
Directed evolution of bacterial polysialyltransferases
Janesch, Bettina, Baumann, Lars, Mark, Alison, Thompson, Nicole, Rahmani, Sadia, Sim, Lyann, Withers, Stephen G, Wakarchuk, Warren W
Published in Glycobiology (Oxford) (01.07.2019)
Published in Glycobiology (Oxford) (01.07.2019)
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Journal Article
Proteolytic Cleavage Driven by Glycosylation
Kötzler, Miriam P., Withers, Stephen G.
Published in The Journal of biological chemistry (01.01.2016)
Published in The Journal of biological chemistry (01.01.2016)
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