The Gymnosperm Cytochrome P450 CYP750B1 Catalyzes Stereospecific Monoterpene Hydroxylation of (+)-Sabinene in Thujone Biosynthesis in Western Redcedar
Gesell, Andreas, Blaukopf, Markus, Madilao, Lina, Yuen, Macaire M.S., Withers, Stephen G., Mattsson, Jim, Russell, John H., Bohlmann, Jörg
Published in Plant physiology (Bethesda) (01.05.2015)
Published in Plant physiology (Bethesda) (01.05.2015)
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Journal Article
Fluorinated mechanism-based inhibitors: common themes and recent developments
Tysoe, Christina, Withers, Stephen G
Published in Current topics in medicinal chemistry (01.04.2014)
Published in Current topics in medicinal chemistry (01.04.2014)
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Journal Article
Toward Efficient Enzymes for the Generation of Universal Blood through Structure-Guided Directed Evolution
Kwan, David H, Constantinescu, Iren, Chapanian, Rafi, Higgins, Melanie A, Kötzler, Miriam P, Samain, Eric, Boraston, Alisdair B, Kizhakkedathu, Jayachandran N, Withers, Stephen G
Published in Journal of the American Chemical Society (06.05.2015)
Published in Journal of the American Chemical Society (06.05.2015)
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Journal Article
N -Alkylated Iminosugar Based Ligands: Synthesis and Inhibition of Human Lysosomal β-Glucocerebrosidase
Wolfsgruber, Andreas, Thonhofer, Martin, Weber, Patrick, Nasseri, Seyed A, Fischer, Roland, Schalli, Michael, Stütz, Arnold E, Withers, Stephen G, Wrodnigg, Tanja M
Published in Molecules (Basel, Switzerland) (11.10.2020)
Published in Molecules (Basel, Switzerland) (11.10.2020)
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Journal Article
Carbohydrate-active enzymes (CAZymes) in the gut microbiome
Wardman, Jacob F., Bains, Rajneesh K., Rahfeld, Peter, Withers, Stephen G.
Published in Nature reviews. Microbiology (01.09.2022)
Published in Nature reviews. Microbiology (01.09.2022)
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Journal Article
X-ray crystallographic structure of a bacterial polysialyltransferase provides insight into the biosynthesis of capsular polysialic acid
Lizak, Christian, Worrall, Liam J., Baumann, Lars, Pfleiderer, Moritz M., Volkers, Gesa, Sun, Tianjun, Sim, Lyann, Wakarchuk, Warren, Withers, Stephen G., Strynadka, Natalie C. J.
Published in Scientific reports (19.07.2017)
Published in Scientific reports (19.07.2017)
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Journal Article
Fluorescence Activated Cell Sorting as a General Ultra-High-Throughput Screening Method for Directed Evolution of Glycosyltransferases
Yang, Guangyu, Rich, Jamie R, Gilbert, Michel, Wakarchuk, Warren W, Feng, Yan, Withers, Stephen G
Published in Journal of the American Chemical Society (04.08.2010)
Published in Journal of the American Chemical Society (04.08.2010)
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Journal Article
Self-Immobilizing Fluorogenic Imaging Agents of Enzyme Activity
Kwan, David H., Chen, Hong-Ming, Ratananikom, Khakhanang, Hancock, Susan M., Watanabe, Yoichiro, Kongsaeree, Prachumporn T., Samuels, A. Lacey, Withers, Stephen G.
Published in Angewandte Chemie (International ed.) (03.01.2011)
Published in Angewandte Chemie (International ed.) (03.01.2011)
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Journal Article
The Structure of Clostridium perfringens NanI Sialidase and Its Catalytic Intermediates
Newstead, Simon L., Potter, Jane A., Wilson, Jennifer C., Xu, Guogang, Chien, Chin-Hsiang, Watts, Andrew G., Withers, Stephen G., Taylor, Garry L.
Published in The Journal of biological chemistry (04.04.2008)
Published in The Journal of biological chemistry (04.04.2008)
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Journal Article
High-throughput screening methodology for the directed evolution of glycosyltransferases
Withers, Stephen G, Aharoni, Amir, Thieme, Karena, Chiu, Cecilia P C, Buchini, Sabrina, Lairson, Luke L, Chen, Hongming, Strynadka, Natalie C J, Wakarchuk, Warren W
Published in Nature methods (01.08.2006)
Published in Nature methods (01.08.2006)
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Journal Article
Mechanistic Insights into the Chaperoning of Human Lysosomal-Galactosidase Activity: Highly Functionalized Aminocyclopentanes and C -5a-Substituted Derivatives of 4- epi -Isofagomine
Weber, Patrick, Thonhofer, Martin, Averill, Summer, Davies, Gideon J, Santana, Andres Gonzalez, Müller, Philipp, Nasseri, Seyed A, Offen, Wendy A, Pabst, Bettina M, Paschke, Eduard, Schalli, Michael, Torvisco, Ana, Tschernutter, Marion, Tysoe, Christina, Windischhofer, Werner, Withers, Stephen G, Wolfsgruber, Andreas, Wrodnigg, Tanja M, Stütz, Arnold E
Published in Molecules (Basel, Switzerland) (03.09.2020)
Published in Molecules (Basel, Switzerland) (03.09.2020)
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Journal Article
Periplasmic de-acylase helps bacteria don their biofilm coat
Kwan, David H., Withers, Stephen G.
Published in Proceedings of the National Academy of Sciences - PNAS (29.07.2014)
Published in Proceedings of the National Academy of Sciences - PNAS (29.07.2014)
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Journal Article
Mechanistic Investigations of Unsaturated Glucuronyl Hydrolase from Clostridium perfringens
Jongkees, Seino A.K., Yoo, Hayoung, Withers, Stephen G.
Published in The Journal of biological chemistry (18.04.2014)
Published in The Journal of biological chemistry (18.04.2014)
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Journal Article
The Staudinger/aza-Wittig/Grignard reaction as key step for the concise synthesis of 1-C-Alkyl-iminoalditol glycomimetics
Zoidl, Manuel, Gonzalez Santana, Andres, Torvisco, Ana, Tysoe, Christina, Siriwardena, Aloysius, Withers, Stephen G., Wrodnigg, Tanja M.
Published in Carbohydrate research (24.06.2016)
Published in Carbohydrate research (24.06.2016)
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Journal Article
Tuning Mechanism-Based Inactivators of Neuraminidases: Mechanistic and Structural Insights
Buchini, Sabrina, Gallat, François-Xavier, Greig, Ian R., Kim, Jin-Hyo, Wakatsuki, Soichi, Chavas, Leonard M. G., Withers, Stephen G.
Published in Angewandte Chemie (International ed.) (24.03.2014)
Published in Angewandte Chemie (International ed.) (24.03.2014)
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