A concise synthesis of the molecular framework of pleuromutilin
Liu, Junjia, Lotesta, Stephen D., Sorensen, Erik J.
Published in Chemical communications (Cambridge, England) (01.01.2011)
Published in Chemical communications (Cambridge, England) (01.01.2011)
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Spirodiepoxide Strategy to the C Ring of Pectenotoxin 4: Synthesis of the C1−C19 Sector
Joyasawal, Sipak, Lotesta, Stephen D, Akhmedov, N. G, Williams, Lawrence J
Published in Organic letters (05.03.2010)
Published in Organic letters (05.03.2010)
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Identification of spirooxindole and dibenzoxazepine motifs as potent mineralocorticoid receptor antagonists
Lotesta, Stephen D., Marcus, Andrew P., Zheng, Yajun, Leftheris, Katerina, Noto, Paul B., Meng, Shi, Kandpal, Geeta, Chen, Guozhou, Zhou, Jing, McKeever, Brian, Bukhtiyarov, Yuri, Zhao, Yi, Lala, Deepak S., Singh, Suresh B., McGeehan, Gerard M.
Published in Bioorganic & medicinal chemistry (15.03.2016)
Published in Bioorganic & medicinal chemistry (15.03.2016)
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Discovery of a Novel, Orally Efficacious Liver X Receptor (LXR) β Agonist
Zheng, Yajun, Zhuang, Linghang, Fan, Kristi Yi, Tice, Colin M, Zhao, Wei, Dong, Chengguo, Lotesta, Stephen D, Leftheris, Katerina, Lindblom, Peter R, Liu, Zhijie, Shimada, Jun, Noto, Paul B, Meng, Shi, Hardy, Andrew, Howard, Lamont, Krosky, Paula, Guo, Joan, Lipinski, Kerri, Kandpal, Geeta, Bukhtiyarov, Yuri, Zhao, Yi, Lala, Deepak, Van Orden, Rebecca, Zhou, Jing, Chen, Guozhou, Wu, Zhongren, McKeever, Brian M, McGeehan, Gerard M, Gregg, Richard E, Claremon, David A, Singh, Suresh B
Published in Journal of medicinal chemistry (14.04.2016)
Published in Journal of medicinal chemistry (14.04.2016)
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Spirodiepoxide Reaction with Cuprates
Ghosh, Partha, Lotesta, Stephen D, Williams, Lawrence J
Published in Journal of the American Chemical Society (07.03.2007)
Published in Journal of the American Chemical Society (07.03.2007)
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Brain penetrant liver X receptor (LXR) modulators based on a 2,4,5,6-tetrahydropyrrolo[3,4-c]pyrazole core
Tice, Colin M., Noto, Paul B., Fan, Kristi Yi, Zhao, Wei, Lotesta, Stephen D., Dong, Chengguo, Marcus, Andrew P., Zheng, Ya-Jun, Chen, Guozhou, Wu, Zhongren, Van Orden, Rebecca, Zhou, Jing, Bukhtiyarov, Yuri, Zhao, Yi, Lipinski, Kerri, Howard, Lamont, Guo, Joan, Kandpal, Geeta, Meng, Shi, Hardy, Andrew, Krosky, Paula, Gregg, Richard E., Leftheris, Katerina, McKeever, Brian M., Singh, Suresh B., Lala, Deepak, McGeehan, Gerard M., Zhuang, Linghang, Claremon, David A.
Published in Bioorganic & medicinal chemistry letters (15.10.2016)
Published in Bioorganic & medicinal chemistry letters (15.10.2016)
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Spirodiepoxides in Total Synthesis: Epoxomicin
Katukojvala, Sreenivas, Barlett, Kristin N, Lotesta, Stephen D, Williams, Lawrence J
Published in Journal of the American Chemical Society (01.12.2004)
Published in Journal of the American Chemical Society (01.12.2004)
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INHIBITORS OF MENIN-MLL INTERACTION
DAVID A CLAREMON, SURESH B SINGH, SALVACION CACATIAN, ANDREW MARCUS, ANGEL MORALES-RAMOS, STEPHEN D LOTESTA, ZHENG YAJUN, ZHUANG LINGHANG, JIA LANQI, TRAVIS L HOUSTON, YI FAN, SHANKAR VENKATRAMAN, YUAN JING, DONG CHENGGUO, STEPHAN D PARENT, LAWRENCE WAYNE DILLARD
Year of Publication 02.04.2024
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Year of Publication 02.04.2024
Patent
BENZIMIDAZOLE DERIVATIVES AS MODULATORS OF ROR-GAMMA
DAVID A CLAREMON, SINGH SURESH B, LAWRENCE WAYNE DILLARD, STEPHEN D LOTESTA, ZHAO WEI, ZHUANG LINGHANG, TICE COLIN M, FAN YI
Year of Publication 23.12.2021
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Year of Publication 23.12.2021
Patent
A concise synthesis of the molecular framework of pleuromutilinElectronic supplementary information (ESI) available: Experimental procedures, characterization of new compounds and spectra. CCDC 798052 (13) and 798053 (31). For ESI and crystallographic data in CIF or other electronic format see DOI: 10.1039/c0cc04077k
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Journal Article
Identification of spirooxindole and dibenzoxazepine motifs as potent mineralocorticoid receptor antagonists
Lotesta, Stephen D., Marcus, Andrew P., Zheng, Yajun, Leftheris, Katerina, Noto, Paul B., Meng, Shi, Kandpal, Geeta, Chen, Guozhou, Zhou, Jing, McKeever, Brian, Bukhtiyarov, Yuri, Zhao, Yi, Lala, Deepak S., Singh, Suresh B., McGeehan, Gerard M.
Published in Bioorganic & medicinal chemistry (01.03.2016)
Published in Bioorganic & medicinal chemistry (01.03.2016)
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Journal Article
Spirodiepoxideso: Heterocycle synthesis and mechanistic insight
Lotesta, Stephen D., Kiren, Sezgin, Sauers, Ronald R., Williams, Lawrence J.
Published in Angewandte Chemie International Edition (01.01.2007)
Published in Angewandte Chemie International Edition (01.01.2007)
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Structure and reactivity of a chiral cyclononadienone
Zhang, Yue, Lotesta, Stephen D., Emge, Thomas J., Williams, Lawrence J.
Published in Tetrahedron letters (29.04.2009)
Published in Tetrahedron letters (29.04.2009)
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Journal Article
INHIBITORS OF THE MENIN-MLL INTERACTION
DONG, Chengguo, LOTESTA, Stephen D, CACATIAN, Salvacion, ZHUANG, Linghang, JIA, Lanqi, CLAREMON, David A, VENKATRAMAN, Shankar, FAN, Yi, ZHENG, Yajun, YUAN, Jing, SINGH, Suresh B
Year of Publication 18.04.2024
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Year of Publication 18.04.2024
Patent
BENZIMIDAZOLE DERIVATIVES AS MODULATORS OF ROR-GAMMA
CLAREMON, David, A, ZHUANG, Linghang, LOTESTA, Stephen, D, TICE, Colin, M, DILLARD, Lawrence, Wayne, ZHAO, Wei, FAN, Yi, SINGH, Suresh, B
Year of Publication 06.12.2023
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Year of Publication 06.12.2023
Patent
INHIBITORS OF THE MENIN-MLL INTERACTION
DONG, Chengguo, LOTESTA, Stephen D, CACATIAN, Salvacion, ZHUANG, Linghang, JIA, Lanqi, CLAREMON, David A, VENKATRAMAN, Shankar, FAN, Yi, ZHENG, Yajun, YUAN, Jing, SINGH, Suresh B
Year of Publication 15.11.2023
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Year of Publication 15.11.2023
Patent
INHIBITORS OF THE MENIN-MLL INTERACTION
VENKATRAMAN, SHANKAR, CLAREMON, DAVID A, LOTESTA, STEPHEN D, ZHENG, YAJUN, FAN, YI, YUAN, JING, ZHUANG, LINGHANG, JIA, LANQI, SINGH, SURESH B, DONG, CHENGGUO, CACATIAN, SALVACION
Year of Publication 09.10.2023
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Year of Publication 09.10.2023
Patent