Paralog-selective Hsp90 inhibitors define tumor-specific regulation of HER2
Patel, Pallav D, Yan, Pengrong, Seidler, Paul M, Patel, Hardik J, Sun, Weilin, Yang, Chenghua, Que, Nanette S, Taldone, Tony, Finotti, Paola, Stephani, Ralph A, Gewirth, Daniel T, Chiosis, Gabriela
Published in Nature chemical biology (01.11.2013)
Published in Nature chemical biology (01.11.2013)
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Journal Article
Synthesis of N-1′, N-3′-disubstituted spirohydantoins and their anticonvulsant activities in pilocarpine model of temporal lobe epilepsy
Yang, Chen, Schanne, Francis A.X., Yoganathan, Sabesan, Stephani, Ralph A.
Published in Bioorganic & medicinal chemistry letters (15.06.2016)
Published in Bioorganic & medicinal chemistry letters (15.06.2016)
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Journal Article
Synthesis, resolution and anticonvulsant activity of chiral N-1′-ethyl,N-3′-(1-phenylethyl)-(R,S)-2′H,3H,5′H-spiro-(2-benzofuran-1,4′-imidazolidine)-2′,3,5′-trione diastereomers
Sadarangani, Ishwar R., Bhatia, Souful, Amarante, Daniel, Lengyel, Istvan, Stephani, Ralph A.
Published in Bioorganic & medicinal chemistry letters (01.04.2012)
Published in Bioorganic & medicinal chemistry letters (01.04.2012)
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Journal Article
N , N -Dimethylacetamide Regulates the Proinflammatory Response Associated with Endotoxin and Prevents Preterm Birth
Sundaram, Sruthi, Ashby, Charles R, Pekson, Ryan, Sampat, Vaishali, Sitapara, Ravikumar, Mantell, Lin, Chen, Chih-Hung, Yen, Haoting, Abhichandani, Khushboo, Munnangi, Swapna, Khadtare, Nikhil, Stephani, Ralph A, Reznik, Sandra E
Published in The American journal of pathology (01.08.2013)
Published in The American journal of pathology (01.08.2013)
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Journal Article
The novel ETA receptor antagonist HJP-272 prevents cerebral microvascular hemorrhage in cerebral malaria and synergistically improves survival in combination with an artemisinin derivative
Dai, Minxian, Freeman, Brandi, Bruno, Fernando P., Shikani, Henry J., Tanowitz, Herbert B., Weiss, Louis M., Reznik, Sandra E., Stephani, Ralph A., Desruisseaux, Mahalia S.
Published in Life sciences (1973) (15.10.2012)
Published in Life sciences (1973) (15.10.2012)
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Journal Article
An Efficient Copper-Catalyzed Microwave-Assisted S-Arylation towards the Synthesis of 8-Arylsulfanyl Adenines
Sun, Weilin, Patel, Pallav D., Stephani, Ralph A., Chiosis, Gabriela
Published in Synlett (01.12.2011)
Published in Synlett (01.12.2011)
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Journal Article
Synthesis and pharmacological activity of 1,3,6-trisubstituted-4-oxo-1,4-dihydroquinoline-2-carboxylic acids as selective ETA antagonists
Patel, Hardik J., Olgun, Nicole, Lengyel, István, Reznik, Sandra, Stephani, Ralph A.
Published in Bioorganic & medicinal chemistry letters (15.11.2010)
Published in Bioorganic & medicinal chemistry letters (15.11.2010)
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Journal Article
Synthesis and anticonvulsant activity of new N-1′,N-3′-disubstituted-2′H,3H,5′H-spiro-(2-benzofuran-1,4′-imidazolidine)-2′,3,5′-triones
Patel, Hardik J., Sarra, Joe, Caruso, Francesco, Rossi, Miriam, Doshi, Utkarsh, Stephani, Ralph A.
Published in Bioorganic & medicinal chemistry letters (01.09.2006)
Published in Bioorganic & medicinal chemistry letters (01.09.2006)
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Journal Article
Synthesis, resolution and anticonvulsant activity of chiral N-1'-ethyl,N-3'-(1-phenylethyl)-(R,S)-2'H,3H,5'H-spiro-(2-benzofuran-1,4'-imidazolidine)-2',3,5'-trione diastereomers
SADARANGANI, Ishwar R, BHATIA, Souful, AMARANTE, Daniel, LENGYEL, Istvan, STEPHANI, Ralph A
Published in Bioorganic & medicinal chemistry letters (01.04.2012)
Published in Bioorganic & medicinal chemistry letters (01.04.2012)
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Journal Article
Synthesis and anticonvulsant activity of new N-1',N-3'-disubstituted-2'H,3H,5'H-spiro-(2-benzofuran-1,4'-imidazolidine)-2',3,5'-triones
Patel, Hardik J, Sarra, Joe, Caruso, Francesco, Rossi, Miriam, Doshi, Utkarsh, Stephani, Ralph A
Published in Bioorganic & medicinal chemistry letters (01.09.2006)
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Published in Bioorganic & medicinal chemistry letters (01.09.2006)
Journal Article
Synthesis and anticonvulsant activity of new N-1',N-3'-disubstituted- 2'H,3H,5'H-spiro-(2-benzofuran-1,4'-imidazolidine)-2',3,5'-trio nes
Patel, Hardik J, Sarra, Joe, Caruso, Francesco, Rossi, Miriam, Doshi, Utkarsh, Stephani, Ralph A
Published in Bioorganic & medicinal chemistry letters (01.09.2006)
Published in Bioorganic & medicinal chemistry letters (01.09.2006)
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Journal Article
Synthesis and anticonvulsant activity of new N-1',N-31-disubstituted-2'H,3H,5'H-spiro-(2-benzofuran-1,4'-imidazolidine)-2',3,5'-triones
PATEL, Hardik J, SARRA, Joe, CARUSO, Francesco, ROSSI, Miriam, DOSHI, Utkarsh, STEPHANI, Ralph A
Published in Bioorganic & medicinal chemistry letters (2006)
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Published in Bioorganic & medicinal chemistry letters (2006)
Journal Article
Synthesis and anticonvulsant activity of new N-1′,N-3′-disubstituted-2′ H,3 H,5′ H-spiro-(2-benzofuran-1,4′-imidazolidine)-2′,3,5′-triones
Patel, Hardik J., Sarra, Joe, Caruso, Francesco, Rossi, Miriam, Doshi, Utkarsh, Stephani, Ralph A.
Published in Bioorganic & medicinal chemistry letters (2006)
Published in Bioorganic & medicinal chemistry letters (2006)
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Journal Article
Synthesis and pharmacological activity of 1,3,6-trisubstituted-4-oxo-1,4-dihydroquinoline-2-carboxylic acids as selective ET(A) antagonists
Patel, Hardik J, Olgun, Nicole, Lengyel, István, Reznik, Sandra, Stephani, Ralph A
Published in Bioorganic & medicinal chemistry letters (15.11.2010)
Published in Bioorganic & medicinal chemistry letters (15.11.2010)
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Journal Article
Accumulation of 5-Oxoproline in Mouse Tissues after Inhibition of 5-Oxoprolinase and Administration of Amino Acids: Evidence for Function of the γ -Glutamyl Cycle
Van Der Werf, Paul, Stephani, Ralph A., Meister, Alton
Published in Proceedings of the National Academy of Sciences - PNAS (01.04.1974)
Published in Proceedings of the National Academy of Sciences - PNAS (01.04.1974)
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Journal Article
Inhibition of 5-oxoprolinase by 2-imidazolidone-4-carboxylic Acid
Van Der Werf, Paul, Stephani, Ralph A., Orlowski, Marian, Meister, Alton
Published in Proceedings of the National Academy of Sciences - PNAS (01.03.1973)
Published in Proceedings of the National Academy of Sciences - PNAS (01.03.1973)
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